SKAP2 (src kinase associated phosphoprotein 2) - Rat Genome Database

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Gene: SKAP2 (src kinase associated phosphoprotein 2) Chlorocebus sabaeus
Analyze
Symbol: SKAP2
Name: src kinase associated phosphoprotein 2
RGD ID: 18342457
Description: INVOLVED IN negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: src kinase-associated phosphoprotein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,499,084 - 31,698,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604273,035,780 - 73,237,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SKAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,499,084 - 31,698,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604273,035,780 - 73,237,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SKAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38726,654,770 - 26,864,590 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl726,667,068 - 26,995,239 (-)EnsemblGRCh38hg38GRCh38
GRCh37726,706,687 - 26,904,209 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36726,673,212 - 26,870,866 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,479,928 - 26,677,581NCBI
Celera726,695,659 - 26,893,221 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef726,587,650 - 26,785,497 (-)NCBIHuRef
CHM1_1726,706,403 - 26,904,093 (-)NCBICHM1_1
T2T-CHM13v2.0726,790,493 - 27,000,391 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2726,757,875 - 26,955,499 (-)NCBI
Skap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39651,836,145 - 51,989,529 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl651,834,402 - 51,989,529 (-)EnsemblGRCm39 Ensembl
GRCm38651,859,165 - 52,012,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl651,857,422 - 52,012,549 (-)EnsemblGRCm38mm10GRCm38
MGSCv37651,809,164 - 51,962,548 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36651,788,748 - 51,942,132 (-)NCBIMGSCv36mm8
Celera652,378,898 - 52,532,331 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.35NCBI
Skap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,281,221 - 82,431,664 (-)NCBIGRCr8
mRatBN7.2480,948,832 - 81,100,900 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl480,950,580 - 81,100,891 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,172,672 - 86,322,749 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0481,948,069 - 82,098,144 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,375,899 - 80,525,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0481,816,778 - 81,968,832 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,818,569 - 81,968,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04146,483,609 - 146,635,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,149,846 - 80,300,111 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,425,975 - 80,576,241 (-)NCBI
Celera475,843,093 - 75,993,070 (-)NCBICelera
Cytogenetic Map4q24NCBI
Skap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,446,070 - 28,618,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,447,073 - 28,618,450 (-)NCBIChiLan1.0ChiLan1.0
SKAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,493,712 - 31,690,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1779,818,438 - 80,014,919 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,309,599 - 27,505,842 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1726,910,341 - 27,106,680 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl726,911,734 - 27,106,285 (-)Ensemblpanpan1.1panPan2
SKAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11439,914,285 - 40,261,782 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1439,916,343 - 40,092,188 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,410,666 - 39,484,230 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01439,853,120 - 40,031,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1439,853,128 - 40,031,292 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11439,967,512 - 40,145,669 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01439,654,150 - 39,832,319 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,011,247 - 40,189,175 (-)NCBIUU_Cfam_GSD_1.0
Skap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,181,694 - 84,408,048 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,393,493 - 3,566,264 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,393,425 - 3,566,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SKAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,637,360 - 45,790,259 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,636,929 - 45,813,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_007981821   ⟹   XP_007980012
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12131,499,084 - 31,698,663 (+)NCBI
Vero_WHO_p1.0NW_02366604273,035,780 - 73,237,316 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038004762   ⟹   XP_037860690
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604273,035,780 - 73,237,316 (-)NCBI
RefSeq Acc Id: XM_038004763   ⟹   XP_037860691
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604273,035,780 - 73,124,788 (-)NCBI
RefSeq Acc Id: XM_038004764   ⟹   XP_037860692
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604273,035,780 - 73,229,608 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007980012 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860690 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860691 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010336.1
Reference Protein Sequences
RefSeq Acc Id: XP_007980012   ⟸   XM_007981821
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037860690   ⟸   XM_038004762
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037860692   ⟸   XM_038004764
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037860691   ⟸   XM_038004763
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RNZ7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014230 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012295.1 UniProtKB/TrEMBL
Gene3D-CATH Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SKAP_fam UniProtKB/TrEMBL
NCBI Gene SKAP2 ENTREZGENE
PANTHER SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 UniProtKB/TrEMBL
  SRC-ASSOCIATED ADAPTOR PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SH3-domain UniProtKB/TrEMBL
UniProt A0A0D9RNZ7 ENTREZGENE, UniProtKB/TrEMBL