Exhibits neuropeptide hormone activity. Involved in several processes, including learning or memory; positive regulation of cellular protein metabolic process; and regulation of behavioral fear response. Localizes to several cellular components, including the axon; dendrite; and perikaryon. Used to study cataract. Orthologous to human CCK (cholecystokinin); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.
Tetrachlorodibenzodioxin results in decreased expression of CCK mRNA, Tetrachlorodibenzodioxin results in decreased expression of CCK protein alternative form
Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein], Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]
Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK mRNA], Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK protein]
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]], CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]
[[orlistat results in decreased abundance of Fatty Acids, Nonesterified] which results in decreased secretion of CCK protein] which results in decreased secretion of PNLIP protein more ...
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCK mRNA
[NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCK mRNA
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
over-lapped AP-2- and NF-kB-responsive elements within the 17-base pair sequence between 2149 and 2134 of the distal 5 flanking region||several cis-elements, important in transcriptional control, identified within the first 119 bp of the 59 flanking regio
Gene-Chemical Interaction Annotations
