Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cck (cholecystokinin) Mus musculus
Analyze
Symbol: Cck
Name: cholecystokinin
Description: This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Homozygous knockout mice for this gene exhibit impaired insulin secretion, enhanced insulin sensitivity, and resistance to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Orthologs:
Homo sapiens (human) : CCK (cholecystokinin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cck (cholecystokinin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cck (cholecystokinin)
Pan paniscus (bonobo/pygmy chimpanzee) : CCK (cholecystokinin)
Canis lupus familiaris (dog) : CCK (cholecystokinin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cck (cholecystokinin)
Sus scrofa (pig) : CCK (cholecystokinin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389121,489,824 - 121,495,694 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379121,398,942 - 121,404,807 (-)NCBIGRCm37mm9NCBIm37
MGSCv369121,338,523 - 121,344,360 (-)NCBImm8
Celera9121,960,523 - 121,966,362 (-)NCBICelera
Cytogenetic Map9 F4NCBI
cM Map972.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cck
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10298
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-01
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.