CCK (cholecystokinin) - Rat Genome Database

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Gene: CCK (cholecystokinin) Homo sapiens
Analyze
Symbol: CCK
Name: cholecystokinin
RGD ID: 737505
HGNC Page HGNC:1569
Description: Enables peptide hormone receptor binding activity. Predicted to be involved in several processes, including cholecystokinin signaling pathway; generation of neurons; and positive regulation of glutamate secretion. Predicted to be located in extracellular region. Predicted to be active in GABA-ergic synapse; axon; and extracellular space. Biomarker of morbid obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cholecystokinin triacontatriapeptide; MGC117187; prepro-cholecystokinin
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,257,826 - 42,266,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,257,825 - 42,266,185 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,299,318 - 42,307,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,274,322 - 42,281,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,274,321 - 42,281,399NCBI
Celera342,238,692 - 42,247,029 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,342,652 - 42,351,001 (-)NCBIHuRef
CHM1_1342,250,425 - 42,258,774 (-)NCBICHM1_1
T2T-CHM13v2.0342,275,821 - 42,284,183 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-acetamidofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-acetyldeoxynivalenol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP)
ammonium chloride  (ISO)
apomorphine  (ISO)
arsenite(3-)  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
bromosulfophthalein  (EXP)
butanal  (EXP)
butyric acid  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
capsaicin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (EXP)
chlorpyrifos  (ISO)
clozapine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
Cuprizon  (ISO)
cylindrospermopsin  (EXP)
deoxynivalenol  (ISO)
devazepide  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diiodine  (ISO)
dinophysistoxin 1  (EXP)
disulfiram  (EXP,ISO)
dizocilpine maleate  (ISO)
dorsomorphin  (EXP)
ethanol  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fenamidone  (ISO)
fluoxetine  (ISO)
folic acid  (ISO)
Fusarenone X  (ISO)
genistein  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (EXP)
irinotecan  (ISO)
kainic acid  (ISO)
ketoconazole  (ISO)
L-365260  (ISO)
malathion  (ISO)
maneb  (ISO)
melatonin  (ISO)
methamphetamine  (ISO)
methotrexate  (EXP)
methylmercury chloride  (EXP)
methylseleninic acid  (EXP)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (EXP)
naloxone  (ISO)
nicotine  (ISO)
nitrendipine  (ISO)
nitrobenzenes  (ISO)
Nivalenol  (ISO)
octreotide  (EXP)
orlistat  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
parathion  (ISO)
parathion-methyl  (ISO)
PCB138  (ISO)
pentanal  (EXP)
perfluorohexanesulfonic acid  (ISO)
progesterone  (ISO)
propanal  (EXP)
resveratrol  (ISO)
rotenone  (EXP)
ruthenium red  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
sodium fluoride  (ISO)
Sodium oleate  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triphenylphosphane oxide  (ISO)
U-73122  (ISO)
valproic acid  (EXP)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Postprandial cholecystokinin release and gastric emptying in patients with bulimia nervosa. Devlin MJ, etal., Am J Clin Nutr. 1997 Jan;65(1):114-20.
2. Association between polymorphism of the cholecystokinin gene and idiopathic Parkinson's disease. Fujii C, etal., Clin Genet. 1999 Nov;56(5):394-9.
3. An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Garvey MJ, etal., Psychiatry Res 1998 Aug 17;80(2):149-53.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. The antagonism of cholecystokinin octapeptide-8 to the peroxynitrite oxidation on a diabetic cataractal rat model. Hao LN, etal., Chin Med J (Engl). 2006 Sep 5;119(17):1451-7.
6. Cholecystokinin octapeptide: a potential growth factor for pancreatic beta cells in diabetic rats. Kuntz E, etal., JOP. 2004 Nov 10;5(6):464-75.
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Peripheral participation of cholecystokinin in the morphine-induced peripheral antinociceptive effect in non-diabetic and diabetic rats. Torres-Lopez JE, etal., Neuropharmacology. 2007 Mar;52(3):788-95. Epub 2006 Dec 6.
9. Cholecystokinin, cholecystokinin-A receptor and cholecystokinin-B receptor gene polymorphisms in Parkinson's disease. Wang J, etal., Pharmacogenetics. 2003 Jun;13(6):365-9.
10. Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance. Xie JY, etal., J Neurosci. 2005 Jan 12;25(2):409-16.
11. Basal and postprandial plasma levels of PPY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome. Zwirska-Korczala K, etal., J Physiol Pharmacol. 2007 Mar;58 Suppl 1:13-35.
Additional References at PubMed
PMID:1370477   PMID:3011648   PMID:3582983   PMID:3856870   PMID:6288173   PMID:6529856   PMID:7681836   PMID:8804068   PMID:9006937   PMID:9275097   PMID:9399627   PMID:9603948  
PMID:10320330   PMID:10400673   PMID:10438490   PMID:10595537   PMID:11025367   PMID:11076522   PMID:11140838   PMID:11232009   PMID:11278902   PMID:11300760   PMID:11368834   PMID:11443535  
PMID:11509018   PMID:11713976   PMID:11713982   PMID:11713985   PMID:11724786   PMID:11803530   PMID:12065614   PMID:12116180   PMID:12116188   PMID:12198366   PMID:12477932   PMID:12479974  
PMID:12572876   PMID:12627463   PMID:12695525   PMID:12789687   PMID:12915664   PMID:12920059   PMID:14764444   PMID:15001692   PMID:15068617   PMID:15100163   PMID:15152034   PMID:15313848  
PMID:15328192   PMID:15354400   PMID:15374756   PMID:15489334   PMID:15520004   PMID:15533776   PMID:15624269   PMID:15682471   PMID:15740988   PMID:15743365   PMID:15837012   PMID:16185316  
PMID:16712791   PMID:16754659   PMID:17192493   PMID:17208296   PMID:17332474   PMID:17365745   PMID:17438102   PMID:17964616   PMID:18066654   PMID:18154642   PMID:18234641   PMID:18396340  
PMID:18423848   PMID:18555802   PMID:18577758   PMID:18996102   PMID:19058789   PMID:19086053   PMID:19339394   PMID:19497313   PMID:19741117   PMID:19760980   PMID:19874574   PMID:19914303  
PMID:20023595   PMID:20036221   PMID:20424473   PMID:20457200   PMID:20468064   PMID:20602615   PMID:20732371   PMID:20734064   PMID:20930049   PMID:21154912   PMID:21186400   PMID:21506165  
PMID:21542221   PMID:21753024   PMID:21873635   PMID:21985915   PMID:22188045   PMID:22344221   PMID:23064014   PMID:23233532   PMID:23349895   PMID:23399917   PMID:23564449   PMID:23597562  
PMID:23975326   PMID:24001751   PMID:24177032   PMID:24252886   PMID:24348519   PMID:24692543   PMID:24914377   PMID:25331205   PMID:25627687   PMID:25984632   PMID:26429068   PMID:26454231  
PMID:26762368   PMID:26878472   PMID:27084212   PMID:27875537   PMID:29381655   PMID:29729168   PMID:30121362   PMID:30902899   PMID:31541684   PMID:32296183   PMID:32814053   PMID:33961781  
PMID:35830620   PMID:36495169   PMID:37258205   PMID:37931511   PMID:38047304  


Genomics

Comparative Map Data
CCK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,257,826 - 42,266,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,257,825 - 42,266,185 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,299,318 - 42,307,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,274,322 - 42,281,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,274,321 - 42,281,399NCBI
Celera342,238,692 - 42,247,029 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,342,652 - 42,351,001 (-)NCBIHuRef
CHM1_1342,250,425 - 42,258,774 (-)NCBICHM1_1
T2T-CHM13v2.0342,275,821 - 42,284,183 (-)NCBIT2T-CHM13v2.0
Cck
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,318,890 - 121,324,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,318,890 - 121,324,760 (-)EnsemblGRCm39 Ensembl
GRCm389121,489,824 - 121,495,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,489,824 - 121,495,694 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,398,942 - 121,404,807 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369121,338,523 - 121,344,360 (-)NCBIMGSCv36mm8
Celera9121,960,523 - 121,966,357 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.43NCBI
Cck
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,031,012 - 130,037,702 (-)NCBIGRCr8
mRatBN7.28121,153,499 - 121,160,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,153,500 - 121,160,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8126,751,677 - 126,758,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08124,950,740 - 124,957,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,780,342 - 122,786,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,120,525 - 130,127,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,120,523 - 130,127,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,312,785 - 129,319,582 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,492,636 - 126,499,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18126,512,372 - 126,518,954 (-)NCBI
Celera8120,288,523 - 120,295,093 (-)NCBICelera
RH 3.4 Map81254.7RGD
RH 3.4 Map81282.1RGD
Cytogenetic Map8q32NCBI
Cck
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,438,806 - 28,443,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542028,438,806 - 28,443,458 (+)NCBIChiLan1.0ChiLan1.0
CCK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,225,061 - 42,233,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,229,822 - 42,238,192 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,168,012 - 42,176,358 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,431,021 - 42,439,396 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,431,022 - 42,439,396 (-)Ensemblpanpan1.1panPan2
CCK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,414,254 - 11,419,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,414,249 - 11,454,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,451,726 - 11,457,488 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02311,701,990 - 11,707,749 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,701,991 - 11,707,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,504,111 - 11,509,872 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,646,349 - 11,652,103 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,650,493 - 11,656,260 (-)NCBIUU_Cfam_GSD_1.0
Cck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,424,409 - 200,429,945 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,776,831 - 2,782,061 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,776,705 - 2,782,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,937,645 - 25,945,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,940,674 - 25,945,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,610,211 - 28,615,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,698,192 - 3,705,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,698,173 - 3,704,956 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041163,500,609 - 163,507,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cck
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473077,309,633 - 77,314,384 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473077,310,080 - 77,314,258 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCK
5 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p22.1(chr3:41880503-42550279)x3 copy number gain See cases [RCV000051465] Chr3:41880503..42550279 [GRCh38]
Chr3:41921995..42591771 [GRCh37]
Chr3:41896999..42566775 [NCBI36]
Chr3:3p22.1
uncertain significance
GRCh38/hg38 3p22.1(chr3:41896597-42336619)x3 copy number gain See cases [RCV000051466] Chr3:41896597..42336619 [GRCh38]
Chr3:41938089..42378111 [GRCh37]
Chr3:41913093..42353115 [NCBI36]
Chr3:3p22.1
uncertain significance
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31
likely pathogenic
GRCh37/hg19 3p22.1-21.31(chr3:41104508-44636698)x1 copy number loss See cases [RCV000240302] Chr3:41104508..44636698 [GRCh37]
Chr3:3p22.1-21.31
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3 copy number gain not provided [RCV000682249] Chr3:16923595..45249923 [GRCh37]
Chr3:3p24.3-21.31
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p22.1(chr3:42008472-42610176)x3 copy number gain not provided [RCV001259688] Chr3:42008472..42610176 [GRCh37]
Chr3:3p22.1
uncertain significance
NC_000003.11:g.(?_40924962)_(43760024_?)dup duplication Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 8 [RCV001979130] Chr3:40924962..43760024 [GRCh37]
Chr3:3p22.1-21.33
uncertain significance
NM_000729.6(CCK):c.104G>A (p.Arg35Gln) single nucleotide variant Inborn genetic diseases [RCV002737248] Chr3:42263527 [GRCh38]
Chr3:42305019 [GRCh37]
Chr3:3p22.1
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:575
Count of miRNA genes:242
Interacting mature miRNAs:254
Transcripts:ENST00000334681, ENST00000396169, ENST00000434608, ENST00000484359
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
GDB:181198  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37342,299,415 - 42,299,697UniSTSGRCh37
Build 36342,274,419 - 42,274,701RGDNCBI36
Celera342,238,789 - 42,239,071RGD
Cytogenetic Map3p22.1UniSTS
HuRef342,342,749 - 42,343,031UniSTS
PMC311033P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37342,306,273 - 42,306,351UniSTSGRCh37
Build 36342,281,277 - 42,281,355RGDNCBI36
Celera342,245,640 - 42,245,718RGD
Cytogenetic Map3p22.1UniSTS
HuRef342,349,612 - 42,349,690UniSTS
SHGC-76858  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37342,299,394 - 42,299,562UniSTSGRCh37
Build 36342,274,398 - 42,274,566RGDNCBI36
Celera342,238,768 - 42,238,936RGD
Cytogenetic Map3p22.1UniSTS
HuRef342,342,728 - 42,342,896UniSTS
TNG Radiation Hybrid Map325775.0UniSTS
GeneMap99-GB4 RH Map3139.71UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High 1 1 2
Medium 159 181 3 20 3 3 26 1696 212 69 1 1 1
Low 1605 91 385 52 121 30 755 801 1070 31 556 597 31 1 143 317 3
Below cutoff 517 1516 769 333 561 217 2554 975 651 129 380 639 121 734 1758

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_000729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC018358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF274749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY514491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC111026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI756101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM544754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB154424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB961869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD250282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR542226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY140623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000334681   ⟹   ENSP00000335657
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl342,257,825 - 42,264,903 (-)Ensembl
RefSeq Acc Id: ENST00000396169   ⟹   ENSP00000379472
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl342,257,826 - 42,266,185 (-)Ensembl
RefSeq Acc Id: ENST00000434608   ⟹   ENSP00000409124
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl342,257,826 - 42,263,947 (-)Ensembl
RefSeq Acc Id: ENST00000484359
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl342,262,984 - 42,264,765 (-)Ensembl
RefSeq Acc Id: NM_000729   ⟹   NP_000720
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38342,257,826 - 42,266,185 (-)NCBI
GRCh37342,299,315 - 42,307,662 (-)NCBI
Build 36342,274,322 - 42,281,399 (-)NCBI Archive
HuRef342,342,652 - 42,351,001 (-)ENTREZGENE
CHM1_1342,250,423 - 42,258,799 (-)NCBI
T2T-CHM13v2.0342,275,821 - 42,284,183 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174138   ⟹   NP_001167609
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38342,257,826 - 42,263,947 (-)NCBI
GRCh37342,299,315 - 42,307,662 (-)NCBI
HuRef342,342,652 - 42,351,001 (-)ENTREZGENE
CHM1_1342,250,423 - 42,256,551 (-)NCBI
T2T-CHM13v2.0342,275,821 - 42,281,946 (-)NCBI
Sequence:
RefSeq Acc Id: NP_000720   ⟸   NM_000729
- Peptide Label: preproprotein
- UniProtKB: P06307 (UniProtKB/Swiss-Prot),   Q6FG82 (UniProtKB/TrEMBL),   A0A024R2P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001167609   ⟸   NM_001174138
- Peptide Label: preproprotein
- UniProtKB: P06307 (UniProtKB/Swiss-Prot),   Q6FG82 (UniProtKB/TrEMBL),   A0A024R2P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000335657   ⟸   ENST00000334681
RefSeq Acc Id: ENSP00000409124   ⟸   ENST00000434608
RefSeq Acc Id: ENSP00000379472   ⟸   ENST00000396169
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06307-F1-model_v2 AlphaFold P06307 1-115 view protein structure

Promoters
RGD ID:6864048
Promoter ID:EPDNEW_H5189
Type:initiation region
Name:CCK_1
Description:cholecystokinin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38342,264,763 - 42,264,823EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1569 AgrOrtholog
COSMIC CCK COSMIC
Ensembl Genes ENSG00000187094 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000334681.9 UniProtKB/Swiss-Prot
  ENST00000396169 ENTREZGENE
  ENST00000396169.7 UniProtKB/Swiss-Prot
  ENST00000434608 ENTREZGENE
  ENST00000434608.1 UniProtKB/Swiss-Prot
GTEx ENSG00000187094 GTEx
HGNC ID HGNC:1569 ENTREZGENE
Human Proteome Map CCK Human Proteome Map
InterPro CCK-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/CCK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/cholecystokinin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:885 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 885 ENTREZGENE
OMIM 118440 OMIM
PANTHER CHOLECYSTOKININ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10786 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Gastrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26141 PharmGKB
PROSITE GASTRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GASTRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R2P8 ENTREZGENE
  CCKN_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6FG82 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A024R2P8 UniProtKB/TrEMBL