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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737505
Species: Homo sapiens
RGD Object: Gene
Symbol: CCK
Name: cholecystokinin
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCKdecreases expressionISOCck (Rattus norvegicus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCK protein alternative formPMID:10919282
CCKmultiple interactionsISOCck (Rattus norvegicus)6480464CTD[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CCK protein alternative form; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran] results in decreased expression of CCK protein alternative formPMID:10919282
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