Sptan1 (spectrin, alpha, non-erythrocytic 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sptan1 (spectrin, alpha, non-erythrocytic 1) Rattus norvegicus
Analyze
Symbol: Sptan1
Name: spectrin, alpha, non-erythrocytic 1
RGD ID: 621714
Description: Enables syntaxin binding activity. Involved in actin cytoskeleton reorganization. Located in plasma membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 5. Orthologous to human SPTAN1 (spectrin alpha, non-erythrocytic 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: a--fodrin; A2a; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin 2; brain alpha-spectrin; fodrin alpha chain; inhibitory protein factor; IPF; noerythroid alpha-spectrin 2; nonerythroid alpha-spectrin 2; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spna2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2313,241,164 - 13,306,047 (+)NCBI
Rnor_6.0 Ensembl38,534,440 - 8,599,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.038,534,437 - 8,599,259 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0313,878,433 - 13,950,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.438,956,380 - 9,021,831 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.138,956,679 - 9,022,131 (+)NCBI
Celera38,018,277 - 8,083,081 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one  (ISO)
(S)-colchicine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,5-hexanedione  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-nitrofluorene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
aconitine  (EXP)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
Brodifacoum  (EXP)
butan-1-ol  (ISO)
Calcimycin  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
Calpeptin  (ISO)
carbon nanotube  (ISO)
chelerythrine  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
Dehydroeburicoic acid  (ISO)
depsipeptide  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethyl fumarate  (ISO)
diethyl maleate  (ISO)
dimethyl maleate  (ISO)
dobutamine  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethylenediaminetetraacetic acid  (EXP)
flutamide  (EXP)
fumonisin B1  (ISO)
furan  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
kainic acid  (EXP)
lactacystin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
methylseleninic acid  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nitroprusside  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium dichromate  (ISO)
staurosporine  (ISO)
styrene oxide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
Tributyltin oxide  (ISO)
triptonide  (ISO)
tungsten  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vitamin E  (ISO)
Z-Val-Phe-H  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. Amano T, etal., Epilepsy Res 2002 Sep;51(1-2):81-91.
2. Bockers TM, etal., J Biol Chem 2001 Oct 26;276(43):40104-12.
3. Cestra G, etal., Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1731-6. Epub 2005 Jan 19.
4. Creighton J, etal., J Cell Sci. 2008 Jan 1;121(Pt 1):110-9. Epub 2007 Dec 11.
5. GOA data from the GO Consortium
6. Hong WJ and Doyle D, J Biol Chem 1989 Aug 5;264(22):12758-64.
7. Kontrogianni-Konstantopoulos A, etal., J Biol Chem. 2001 Jun 8;276(23):20679-87. Epub 2001 Mar 23.
8. Lehtonen S, etal., Am J Pathol. 2004 Sep;165(3):923-36.
9. Lehtonen S, etal., Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9814-9. Epub 2005 Jul 1.
10. Leto TL, etal., Mol Cell Biol 1988 Jan;8(1):1-9.
11. Liu L, etal., Mol Biol Cell. 2006 Oct;17(10):4249-56. Epub 2006 Jul 26.
12. NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Noda Y, etal., Biochem Biophys Res Commun. 2005 May 20;330(4):1041-7.
14. OMIM Disease Annotation Pipeline
15. Ozkan ED, etal., Proc Natl Acad Sci U S A 1997 Apr 15;94(8):4137-42.
16. Papal S, etal., Hum Mol Genet. 2013 Sep 15;22(18):3773-88. doi: 10.1093/hmg/ddt228. Epub 2013 May 23.
17. RGD automated data pipeline
18. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. RGD automated import pipeline for gene-chemical interactions
20. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
21. Tamura Y, etal., J Neurochem 2001 Feb;76(4):1153-64.
Additional References at PubMed
PMID:9670010   PMID:11971983   PMID:12473194   PMID:14593108   PMID:14688621   PMID:15247274   PMID:15673434   PMID:16025302   PMID:16336193   PMID:16396499   PMID:16481394   PMID:16551741  
PMID:16641100   PMID:16882358   PMID:16943668   PMID:17276456   PMID:17634366   PMID:18723693   PMID:18796539   PMID:19292454   PMID:19524114   PMID:20114050   PMID:20131911   PMID:20458337  
PMID:20598904   PMID:22723836   PMID:22871113   PMID:23897824   PMID:24625528   PMID:24769233   PMID:25468996   PMID:28235806   PMID:29337302   PMID:29476059   PMID:29720258   PMID:31859439  


Genomics

Comparative Map Data
Sptan1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2313,241,164 - 13,306,047 (+)NCBI
Rnor_6.0 Ensembl38,534,440 - 8,599,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.038,534,437 - 8,599,259 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0313,878,433 - 13,950,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.438,956,380 - 9,021,831 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.138,956,679 - 9,022,131 (+)NCBI
Celera38,018,277 - 8,083,081 (+)NCBICelera
Cytogenetic Map3p12NCBI
SPTAN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9128,552,558 - 128,633,662 (+)EnsemblGRCh38hg38GRCh38
GRCh389128,552,564 - 128,633,662 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379131,314,866 - 131,395,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,354,687 - 130,435,762 (+)NCBINCBI36hg18NCBI36
Build 349128,394,439 - 128,475,426NCBI
Celera9101,965,660 - 102,046,740 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,926,750 - 101,007,765 (+)NCBIHuRef
CHM1_19131,465,810 - 131,546,871 (+)NCBICHM1_1
Sptan1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,855,572 - 29,921,463 (+)NCBIGRCm39mm39
GRCm39 Ensembl229,855,572 - 29,921,463 (+)Ensembl
GRCm38229,965,560 - 30,031,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl229,965,560 - 30,031,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv37229,821,080 - 29,886,971 (+)NCBIGRCm37mm9NCBIm37
MGSCv36229,787,569 - 29,853,460 (+)NCBImm8
Celera229,669,500 - 29,735,203 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map220.93NCBI
Sptan1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,016,510 - 1,076,499 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,016,510 - 1,076,499 (+)NCBIChiLan1.0ChiLan1.0
SPTAN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19128,341,739 - 128,422,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,341,739 - 128,422,971 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0999,674,819 - 99,755,973 (+)NCBIMhudiblu_PPA_v0panPan3
SPTAN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,953,751 - 55,015,475 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,953,747 - 55,015,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,149,445 - 54,211,133 (-)NCBI
ROS_Cfam_1.0955,876,077 - 55,937,766 (-)NCBI
UMICH_Zoey_3.1954,635,563 - 54,694,357 (-)NCBI
UNSW_CanFamBas_1.0954,949,366 - 55,011,369 (-)NCBI
UU_Cfam_GSD_1.0955,041,985 - 55,103,647 (-)NCBI
Sptan1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,302,505 - 196,374,135 (+)NCBI
SpeTri2.0NW_00493648716,071,043 - 16,142,662 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPTAN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,936,025 - 269,002,261 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,936,120 - 269,002,261 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,959,613 - 303,025,990 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPTAN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,503,752 - 9,585,297 (-)NCBI
ChlSab1.1 Ensembl129,503,367 - 9,585,268 (-)Ensembl
Vero_WHO_p1.0NW_0236660796,662,808 - 6,746,597 (+)NCBI
Sptan1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247606,331,554 - 6,388,953 (-)NCBI

Position Markers
BF390992  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,296,991 - 13,297,171 (+)MAPPER
Rnor_6.038,590,204 - 8,590,383NCBIRnor6.0
Rnor_5.0313,941,916 - 13,942,095UniSTSRnor5.0
RGSC_v3.439,012,777 - 9,012,956UniSTSRGSC3.4
Celera38,074,027 - 8,074,206UniSTS
RH 3.4 Map352.6UniSTS
Cytogenetic Map3p12UniSTS
RH133209  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,306,136 - 13,306,335 (+)MAPPER
Rnor_6.038,599,349 - 8,599,547NCBIRnor6.0
Rnor_5.0313,951,061 - 13,951,259UniSTSRnor5.0
RGSC_v3.439,021,922 - 9,022,120UniSTSRGSC3.4
Celera38,083,172 - 8,083,370UniSTS
RH 3.4 Map335.9UniSTS
Cytogenetic Map3p12UniSTS
RH134500  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,305,800 - 13,305,983 (+)MAPPER
Rnor_6.038,599,013 - 8,599,195NCBIRnor6.0
Rnor_5.0313,950,725 - 13,950,907UniSTSRnor5.0
RGSC_v3.439,021,586 - 9,021,768UniSTSRGSC3.4
Celera38,082,836 - 8,083,018UniSTS
Cytogenetic Map3p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3125786001Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3128136884Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3128500807Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3132972944Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3137891710Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3139773425Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3195176874Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3263142133477544Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3263142148562146Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3328592928136884Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3328592928136884Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)3565463925105730Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)3600074851687917Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)3600074851687917Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)3600086634394121Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)3600086634394121Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)3600086634394121Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:254
Count of miRNA genes:167
Interacting mature miRNAs:176
Transcripts:ENSRNOT00000045827
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_171983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF084186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ502182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M19726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045827   ⟹   ENSRNOP00000042382
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl38,534,440 - 8,599,258 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079108   ⟹   ENSRNOP00000071811
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl38,547,349 - 8,598,917 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079640   ⟹   ENSRNOP00000070932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl38,537,350 - 8,599,060 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082672   ⟹   ENSRNOP00000068710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl38,534,476 - 8,599,260 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091697   ⟹   ENSRNOP00000072038
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl38,547,349 - 8,598,918 (+)Ensembl
RefSeq Acc Id: NM_171983   ⟹   NP_741984
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,241,217 - 13,306,046 (+)NCBI
Rnor_6.038,534,440 - 8,599,258 (+)NCBI
Rnor_5.0313,878,433 - 13,950,970 (+)NCBI
RGSC_v3.438,956,380 - 9,021,831 (+)RGD
Celera38,018,277 - 8,083,081 (+)RGD
Sequence:
RefSeq Acc Id: XM_008761673   ⟹   XP_008759895
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,241,164 - 13,306,047 (+)NCBI
Rnor_6.038,534,437 - 8,599,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008761678   ⟹   XP_008759900
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,241,164 - 13,306,047 (+)NCBI
Rnor_6.038,534,437 - 8,599,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105782   ⟹   XP_038961710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,254,126 - 13,306,047 (+)NCBI
RefSeq Acc Id: XM_039105783   ⟹   XP_038961711
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,254,126 - 13,306,047 (+)NCBI
RefSeq Acc Id: XM_039105784   ⟹   XP_038961712
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,254,126 - 13,306,047 (+)NCBI
RefSeq Acc Id: XM_039105785   ⟹   XP_038961713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,254,126 - 13,306,047 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_741984   ⟸   NM_171983
- Sequence:
RefSeq Acc Id: XP_008759895   ⟸   XM_008761673
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K1Y8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759900   ⟸   XM_008761678
- Peptide Label: isoform X6
- UniProtKB: Q6IRK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068710   ⟸   ENSRNOT00000082672
RefSeq Acc Id: ENSRNOP00000042382   ⟸   ENSRNOT00000045827
RefSeq Acc Id: ENSRNOP00000071811   ⟸   ENSRNOT00000079108
RefSeq Acc Id: ENSRNOP00000070932   ⟸   ENSRNOT00000079640
RefSeq Acc Id: ENSRNOP00000072038   ⟸   ENSRNOT00000091697
RefSeq Acc Id: XP_038961712   ⟸   XM_039105784
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038961710   ⟸   XM_039105782
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961711   ⟸   XM_039105783
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961713   ⟸   XM_039105785
- Peptide Label: isoform X5
Protein Domains
EF-hand   SH3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691948
Promoter ID:EPDNEW_R2473
Type:single initiation site
Name:Sptan1_1
Description:spectrin, alpha, non-erythrocytic 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.038,534,436 - 8,534,496EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621714 AgrOrtholog
Ensembl Genes ENSRNOG00000015396 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042382 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000068710 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000070932 UniProtKB/TrEMBL
  ENSRNOP00000071811 UniProtKB/TrEMBL
  ENSRNOP00000072038 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045827 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079108 UniProtKB/TrEMBL
  ENSRNOT00000079640 UniProtKB/TrEMBL
  ENSRNOT00000082672 UniProtKB/TrEMBL
  ENSRNOT00000091697 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7098134 IMAGE-MGC_LOAD
InterPro Alpha_Spectrin_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_Ca_insen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64159 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91394 IMAGE-MGC_LOAD
NCBI Gene 64159 ENTREZGENE
Pfam EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFhand_Ca_insen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sptan1 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZ69_RAT UniProtKB/TrEMBL
  A0A0G2K1E7_RAT UniProtKB/TrEMBL
  A0A0G2K1Y8 ENTREZGENE, UniProtKB/TrEMBL
  P16086 ENTREZGENE
  Q6IRK8 ENTREZGENE, UniProtKB/TrEMBL
  SPTN1_RAT UniProtKB/Swiss-Prot
UniProt Secondary O88663 UniProtKB/Swiss-Prot
  P70477 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-01-05 Sptan1  spectrin, alpha, non-erythrocytic 1  Sptan1  spectrin, alpha, non-erythrocytic 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Spna2  alpha-spectrin 2      Symbol and Name updated 629477 APPROVED
2003-03-12 Spna2  alpha-spectrin 2  A2a  alpha-fodrin  Data Merged 628472 PROVISIONAL
2002-08-07 Spna2  noerythroid alpha-spectrin 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 A2a  alpha-fodrin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains binds to actin (beta-subunit) and calmodulin (alpha-subunit) 628460
gene_expression expressed in liver, kidney, brain, heart, intestine, lung, testis, stomach, spleen, and muscle  
gene_expression expressed in the hippocampus and cerebellum; present in the neuronal dendritic compartment and with strong enrichment toward dendritic spines and postsynaptic densities 628460
gene_function may act as the precursor to inhibitory protein factor (IPF), which inhibits synaptic vesicle uptake of glutamine and GABA 634094
gene_physical_interaction binds to actin (beta-subunit) and calmodulin (alpha-subunit) 628460
gene_physical_interaction interacts with the N-terminal ankyrin repeats of Shank1 and -3 628460
gene_process may play a role in the organization and reorganization of spines and synapses in the central nervous system 628460
gene_protein 260 kDa 628460
gene_regulation calpain protease-mediated degradation is caused by the high Ca++ and induces an increase in the glutamate binding sites 628460