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Gene: Psmb4 (proteasome 20S subunit beta 4) Rattus norvegicus
Symbol: Psmb4
Name: proteasome 20S subunit beta 4
RGD ID: 61877
Description: Predicted to have endopeptidase activity and lipopolysaccharide binding activity. Predicted to be involved in negative regulation of inflammatory response to antigenic stimulus; proteasomal ubiquitin-independent protein catabolic process; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to several cellular components, including ciliary basal body; nucleus; and proteasome core complex, beta-subunit complex. Orthologous to human PSMB4 (proteasome 20S subunit beta 4); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: macropain beta chain; multicatalytic endopeptidase complex beta chain; proteasome (prosome macropain) subunit beta type 4; proteasome (prosome, macropain) subunit, beta type 4; proteasome beta 4 subunit; proteasome beta chain; proteasome chain 3; proteasome subunit beta 4; proteasome subunit beta type-4; RN3
Homo sapiens (human) : PSMB4 (proteasome 20S subunit beta 4)  HGNC  Alliance
Mus musculus (house mouse) : Psmb4 (proteasome (prosome, macropain) subunit, beta type 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psmb4 (proteasome 20S subunit beta 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PSMB4 (proteasome 20S subunit beta 4)
Canis lupus familiaris (dog) : PSMB4 (proteasome 20S subunit beta 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psmb4 (proteasome 20S subunit beta 4)
Sus scrofa (pig) : PSMB4 (proteasome 20S subunit beta 4)
Chlorocebus sabaeus (African green monkey) : PSMB4 (proteasome 20S subunit beta 4)
Heterocephalus glaber (naked mole-rat) : Psmb4 (proteasome 20S subunit beta 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02196,043,546 - 196,046,320 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,043,618 - 196,046,311 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,536,945 - 215,539,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,778,476 - 189,781,169 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12189,732,542 - 189,735,229 (-)NCBI
Celera2174,986,061 - 174,988,835 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Psmb4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61877
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.