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Gene: Ptger3 (prostaglandin E receptor 3) Rattus norvegicus
Symbol: Ptger3
Name: prostaglandin E receptor 3
Description: Exhibits prostaglandin E receptor activity. Involved in several processes, including negative regulation of transport; positive regulation of smooth muscle contraction; and regulation of G protein-coupled receptor signaling pathway. Localizes to several cellular components, including brush border membrane; nuclear membrane; and proximal neuron projection. Used to study asthma and withdrawal disorder. Biomarker of colon cancer; membranous glomerulonephritis; and renovascular hypertension. Orthologous to human PTGER3 (prostaglandin E receptor 3); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
Also known as: EP3; EP3R; PGE receptor EP3 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP3 subtype; prostaglandin E receptor 3 ( subtype EP3); prostaglandin E receptor 3 (subtype EP3); prostaglandin E2 receptor EP3 subtype; prostanoid EP3 receptor; rat kidney prostaglandin Ep3 receptor; Rat kidney prostaglandin EP3 receptor (alternative splicing results in two different receptors EP3a and EP3b); Rep3; rEP3a; rEP3b
Homo sapiens (human) : PTGER3 (prostaglandin E receptor 3)  HGNC  Alliance
Mus musculus (house mouse) : Ptger3 (prostaglandin E receptor 3 (subtype EP3))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptger3 (prostaglandin E receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGER3 (prostaglandin E receptor 3)
Canis lupus familiaris (dog) : PTGER3 (prostaglandin E receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptger3 (prostaglandin E receptor 3)
Sus scrofa (pig) : PTGER3 (prostaglandin E receptor 3)
Chlorocebus sabaeus (African green monkey) : PTGER3 (prostaglandin E receptor 3)
Heterocephalus glaber (naked mole-rat) : Ptger3 (prostaglandin E receptor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02263,895,093 - 263,979,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2263,895,241 - 263,979,698 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02282,614,936 - 282,760,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42255,680,691 - 255,759,202 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12255,695,297 - 255,773,809 (+)NCBI
Celera2238,415,230 - 238,493,209 (+)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ptger3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3435
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.