Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of TRIM35 mRNA | CTD | PMID:24763279 | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TRIM35 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of TRIM35 mRNA | CTD | PMID:26682919 | 1,2-dichloroethane | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TRIM35 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TRIM35 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TRIM35 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRIM35 mRNA | CTD | PMID:17942748 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TRIM35 mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRIM35 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of TRIM35 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TRIM35 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of TRIM35 mRNA | CTD | PMID:30807115 | aflatoxin B1 | decreases methylation | ISO | TRIM35 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TRIM35 intron | CTD | PMID:30157460 | allethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRIM35 protein | CTD | PMID:34896426 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TRIM35 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TRIM35 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TRIM35 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TRIM35 mRNA | CTD | PMID:20106945 more ... | benzo[b]fluoranthene | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TRIM35 mRNA | CTD | PMID:27858113 | bisphenol A | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TRIM35 mRNA | CTD | PMID:26063408 | bisphenol A | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRIM35 mRNA | CTD | PMID:28628672 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TRIM35 mRNA | CTD | PMID:25181051 | carbon nanotube | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM35 mRNA | CTD | PMID:20938992 | chrysene | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | chrysene results in decreased expression of TRIM35 mRNA | CTD | PMID:26377693 | chrysene | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TRIM35 mRNA | CTD | PMID:27858113 | cisplatin | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TRIM35 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TRIM35 mRNA | CTD | PMID:27392435 and PMID:27594783 | clobetasol | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | Clobetasol results in increased expression of TRIM35 mRNA | CTD | PMID:27462272 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of TRIM35 mRNA | CTD | PMID:24386269 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of TRIM35 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of TRIM35 mRNA | CTD | PMID:30556269 | crocidolite asbestos | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of TRIM35 mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TRIM35 mRNA | CTD | PMID:20106945 and PMID:25562108 | cyhalothrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRIM35 protein | CTD | PMID:34896426 | cypermethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRIM35 protein | CTD | PMID:34896426 | dexamethasone | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRIM35 mRNA | CTD | PMID:28628672 | dibutyl phthalate | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of TRIM35 mRNA | CTD | PMID:21266533 | disodium selenite | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of TRIM35 mRNA | CTD | PMID:18175754 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of TRIM35 mRNA | CTD | PMID:29391264 | ethanol | affects splicing | ISO | Trim35 (Mus musculus) | 6480464 | Ethanol affects the splicing of TRIM35 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TRIM35 mRNA | CTD | PMID:23649840 | fenvalerate | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRIM35 protein | CTD | PMID:34896426 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TRIM35 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM35 mRNA | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TRIM35 mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TRIM35 mRNA | CTD | PMID:23649840 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TRIM35 mRNA | CTD | PMID:26194646 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TRIM35 mRNA | CTD | PMID:22061828 | indometacin | multiple interactions | ISO | TRIM35 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRIM35 mRNA | CTD | PMID:28628672 | L-methionine | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM35 mRNA | CTD | PMID:20938992 | lead diacetate | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | lead acetate results in increased expression of TRIM35 mRNA | CTD | PMID:25270620 | malathion | decreases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Malathion results in decreased expression of TRIM35 mRNA | CTD | PMID:32069766 | manganese(II) chloride | decreases expression | EXP | | 6480464 | manganese chloride results in decreased expression of TRIM35 mRNA | CTD | PMID:28801915 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of TRIM35 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TRIM35 mRNA | CTD | PMID:23649840 | miconazole | increases expression | ISO | Trim35 (Mus musculus) | 6480464 | Miconazole results in increased expression of TRIM35 mRNA | CTD | PMID:27462272 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of TRIM35 mRNA | CTD | PMID:19638242 | ozone | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of TRIM35 mRNA | CTD | PMID:27106289 | paracetamol | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TRIM35 mRNA | CTD | PMID:21420995 and PMID:26690555 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TRIM35 mRNA | CTD | PMID:33387578 | pyrethrins | decreases expression | EXP | | 6480464 | Pyrethrins results in decreased expression of TRIM35 protein | CTD | PMID:34896426 | sodium arsenate | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of TRIM35 mRNA | CTD | PMID:30953684 | sunitinib | decreases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TRIM35 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | Testosterone results in decreased expression of TRIM35 mRNA | CTD | PMID:20403060 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TRIM35 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TRIM35 mRNA | CTD | PMID:31150632 | tetraphene | decreases expression | ISO | Trim35 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of TRIM35 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | ISO | Trim35 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TRIM35 mRNA | CTD | PMID:27858113 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TRIM35 mRNA | CTD | PMID:34492290 | urethane | decreases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TRIM35 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | TRIM35 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TRIM35 mRNA | CTD | PMID:23179753 and PMID:29154799 | valproic acid | decreases methylation | ISO | TRIM35 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TRIM35 gene | CTD | PMID:29154799 | |