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Gene: Chmp4b (charged multivesicular body protein 4B) Rattus norvegicus
Symbol: Chmp4b
Name: charged multivesicular body protein 4B
RGD ID: 1309846
Description: Predicted to have protein homodimerization activity. Predicted to be involved in several processes, including midbody abscission; mitotic nuclear division; and regulation of organelle organization. Predicted to localize to several cellular components, including ESCRT III complex; cytoplasmic side of plasma membrane; and midbody. Human ortholog(s) of this gene implicated in cataract 31 multiple types. Orthologous to human CHMP4B (charged multivesicular body protein 4B); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2-methoxyethanol; bisphenol A; 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: chromatin modifying protein 4B; LOC100359642; LOC312254; rCG27912; rCG37275-like; RGD1309846; RGD1565889; similar to RIKEN cDNA 2010012F05
Homo sapiens (human) : CHMP4B (charged multivesicular body protein 4B)  HGNC  Alliance
Mus musculus (house mouse) : Chmp4b (charged multivesicular body protein 4B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chmp4b (charged multivesicular body protein 4B)
Pan paniscus (bonobo/pygmy chimpanzee) : CHMP4B (charged multivesicular body protein 4B)
Canis lupus familiaris (dog) : CHMP4B (charged multivesicular body protein 4B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chmp4b (charged multivesicular body protein 4B)
Sus scrofa (pig) : CHMP4B (charged multivesicular body protein 4B)
Chlorocebus sabaeus (African green monkey) : CHMP4B (charged multivesicular body protein 4B)
Heterocephalus glaber (naked mole-rat) : Chmp4b (charged multivesicular body protein 4B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03150,188,275 - 150,227,453 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,188,455 - 150,227,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03156,559,302 - 156,597,243 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,138,905 - 145,176,471 (+)NCBIRGSC3.4rn4RGSC3.4
Celera3141,903,054 - 141,940,133 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Chmp4b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309846
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.