Gene: Kcnd2 (potassium voltage-gated channel subfamily D member 2) Rattus norvegicus
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Symbol: Kcnd2
Name: potassium voltage-gated channel subfamily D member 2
Description: ENCODES a protein that exhibits A-type (transient outward) potassium channel activity; ion channel activity; potassium channel activity; INVOLVED IN action potential; cardiac muscle cell action potential; cellular response to drug; PARTICIPATES IN excitatory synaptic transmission pathway; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; ASSOCIATED WITH early myoclonic encephalopathy (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN caveola; dendrite; dendritic spine; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Exhibits A-type (transient outward) potassium channel activity, protein heterodimerization activity, and voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential; involved in several processes, including cardiac muscle cell action potential, cellular response to drug, and cellular response to hypoxia; localizes to several cellular components, including the T-tubule, caveola, and intrinsic component of plasma membrane; orthologous to human KCND2 (potassium voltage-gated channel subfamily D member 2).
Merged Description: Exhibits A-type (transient outward) potassium channel activity, protein heterodimerization activity, and voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential; involved in several processes, including cardiac muscle cell action potential, cellular response to drug, and cellular response to hypoxia; localizes to several cellular components, including the T-tubule, caveola, and intrinsic component of plasma membrane; orthologous to human KCND2 (potassium voltage-gated channel subfamily D member 2); PARTICIPATES IN excitatory synaptic transmission pathway; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Kv4.2; potassium channel, voltage-gated Shal-related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; RK5; Shal1; voltage-gated potassium channel subunit Kv4.2
Orthologs:
Homo sapiens (human) : KCND2 (potassium voltage-gated channel subfamily D member 2)  HGNC  Alliance
Mus musculus (house mouse) : Kcnd2 (potassium voltage-gated channel, Shal-related family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kcnd2 (potassium voltage-gated channel subfamily D member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KCND2 (potassium voltage-gated channel subfamily D member 2)
Canis lupus familiaris (dog) : LOC607881 (potassium voltage-gated channel subfamily D member 2-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kcnd2 (potassium voltage-gated channel subfamily D member 2)
Sus scrofa (pig) : KCND2 (potassium voltage-gated channel subfamily D member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0448,309,283 - 48,816,804 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0448,099,455 - 48,609,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4447,541,787 - 48,047,924 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1447,772,679 - 48,277,046 (+)NCBI
Celera444,984,114 - 45,483,230 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Kcnd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 68393
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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