Dpp10 (dipeptidyl peptidase like 10) - Rat Genome Database

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Gene: Dpp10 (dipeptidyl peptidase like 10) Rattus norvegicus
Analyze
Symbol: Dpp10
Name: dipeptidyl peptidase like 10
RGD ID: 1306427
Description: Predicted to enable potassium channel regulator activity and transmembrane transporter binding activity. Predicted to be involved in positive regulation of protein localization to plasma membrane; protein localization to plasma membrane; and regulation of potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in plasma membrane. Biomarker of asthma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human DPP10 (dipeptidyl peptidase like 10); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dipeptidyl peptidase X; dipeptidylpeptidase 10; DPP X; DPPY; inactive dipeptidyl peptidase 10; Kv4 potassium channel auxiliary subunit; LOC363972
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21334,584,420 - 36,269,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1334,595,868 - 36,269,292 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1337,192,650 - 38,846,282 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01338,480,595 - 40,134,245 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01335,751,900 - 37,419,756 (-)NCBIRnor_WKY
Rnor_6.01339,430,590 - 41,173,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1339,434,217 - 39,643,361 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01344,555,443 - 46,284,894 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41335,536,212 - 37,304,931 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11335,550,178 - 36,224,524 (-)NCBI
Celera1334,424,493 - 36,082,282 (-)NCBICelera
Cytogenetic Map13q11-q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Allen M, etal., Nat Genet. 2003 Nov;35(3):258-63. Epub 2003 Oct 19.
2. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
3. Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population. Gao J, etal., Respiration. 2010;79(1):17-24. Epub 2009 Aug 11.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties. Jerng HH, etal., J Physiol. 2005 Nov 1;568(Pt 3):767-88. Epub 2005 Aug 25.
7. Unifying candidate gene and GWAS Approaches in Asthma. Michel S, etal., PLoS One. 2010 Nov 12;5(11):e13894.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. Schade J, etal., J Histochem Cytochem. 2008 Feb;56(2):147-55. Epub 2007 Oct 29.
13. Analyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese population. Zhou H, etal., BMC Med Genet. 2009 Dec 1;10:123.
Additional References at PubMed
PMID:12662155   PMID:15671030   PMID:15911355   PMID:16899223   PMID:17475505   PMID:19713751   PMID:22311982   PMID:25355692   PMID:27198182  


Genomics

Comparative Map Data
Dpp10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21334,584,420 - 36,269,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1334,595,868 - 36,269,292 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1337,192,650 - 38,846,282 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01338,480,595 - 40,134,245 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01335,751,900 - 37,419,756 (-)NCBIRnor_WKY
Rnor_6.01339,430,590 - 41,173,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1339,434,217 - 39,643,361 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01344,555,443 - 46,284,894 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41335,536,212 - 37,304,931 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11335,550,178 - 36,224,524 (-)NCBI
Celera1334,424,493 - 36,082,282 (-)NCBICelera
Cytogenetic Map13q11-q12NCBI
DPP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382114,442,641 - 115,845,780 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2114,442,299 - 115,845,780 (+)EnsemblGRCh38hg38GRCh38
GRCh372115,200,218 - 116,603,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362114,916,369 - 116,318,406 (+)NCBINCBI36Build 36hg18NCBI36
Build 342114,916,128 - 116,318,166NCBI
Celera2108,522,610 - 109,924,481 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2107,520,402 - 108,923,697 (+)NCBIHuRef
CHM1_12115,203,968 - 116,606,429 (+)NCBICHM1_1
T2T-CHM13v2.02114,868,138 - 116,270,550 (+)NCBIT2T-CHM13v2.0
Dpp10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391123,259,871 - 124,773,774 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1123,249,200 - 124,773,776 (-)EnsemblGRCm39 Ensembl
GRCm381123,332,138 - 124,845,815 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1123,321,471 - 124,846,039 (-)EnsemblGRCm38mm10GRCm38
MGSCv371125,228,715 - 125,942,136 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361125,159,688 - 125,873,098 (-)NCBIMGSCv36mm8
Celera1125,992,842 - 126,709,471 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
Dpp10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545913,453,491 - 14,109,194 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545913,456,765 - 14,767,495 (-)NCBIChiLan1.0ChiLan1.0
DPP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B17,182,763 - 17,858,283 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B1,373,640 - 2,775,574 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B114,920,031 - 116,366,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B114,920,488 - 116,362,960 (+)Ensemblpanpan1.1panPan2
DPP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11933,432,091 - 34,707,133 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1933,434,154 - 34,706,758 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1933,715,851 - 33,791,831 (-)NCBIDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha1933,926,232 - 34,250,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01934,868,027 - 36,137,400 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1934,867,763 - 36,136,971 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11933,496,490 - 34,102,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01933,671,202 - 34,944,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01934,897,773 - 36,174,297 (-)NCBIUU_Cfam_GSD_1.0
Dpp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530386,415,799 - 87,669,110 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646953,948,570 - 54,548,747 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493646953,950,034 - 54,548,724 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1520,619,441 - 22,011,994 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11521,365,700 - 22,011,989 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21525,169,920 - 25,353,483 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DPP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11014,434,244 - 15,822,419 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660616,733,336 - 8,137,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dpp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473229,386,401 - 30,042,127 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473229,385,895 - 30,748,424 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dpp10
12759 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000003527
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61453Pur1Proteinuria QTL 118.06urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133453521837415726Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
2292232Pur16Proteinuria QTL 1617.2urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133615572341961389Rat

Markers in Region
D13Rat94  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21336,260,806 - 36,261,020 (+)MAPPERmRatBN7.2
Rnor_6.01341,165,325 - 41,165,538NCBIRnor6.0
Rnor_5.01346,276,513 - 46,276,726UniSTSRnor5.0
RGSC_v3.41337,296,447 - 37,296,659RGDRGSC3.4
RGSC_v3.41337,296,446 - 37,296,659UniSTSRGSC3.4
RGSC_v3.11337,310,412 - 37,310,624RGD
Celera1336,073,799 - 36,074,012UniSTS
RH 2.0 Map13260.5RGD
SHRSP x BN Map138.0099RGD
FHH x ACI Map139.0799RGD
Cytogenetic Map13q11UniSTS
D13Rat115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21334,778,619 - 34,778,759 (+)MAPPERmRatBN7.2
Rnor_6.01339,639,775 - 39,639,912NCBIRnor6.0
Rnor_5.01344,763,184 - 44,763,321UniSTSRnor5.0
RGSC_v3.41335,719,010 - 35,719,148RGDRGSC3.4
RGSC_v3.41335,719,011 - 35,719,148UniSTSRGSC3.4
RGSC_v3.11335,732,698 - 35,733,174RGD
Celera1334,603,625 - 34,603,762UniSTS
RH 2.0 Map13281.2RGD
SHRSP x BN Map137.9399RGD
Cytogenetic Map13q11UniSTS
D13Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,344,325 - 35,344,477 (+)MAPPERmRatBN7.2
Rnor_6.01340,231,399 - 40,231,550NCBIRnor6.0
Rnor_5.01345,348,495 - 45,348,646UniSTSRnor5.0
RGSC_v3.41336,303,945 - 36,304,094RGDRGSC3.4
RGSC_v3.41336,303,946 - 36,304,097UniSTSRGSC3.4
RGSC_v3.11336,317,910 - 36,318,059RGD
Celera1335,161,214 - 35,161,365UniSTS
SHRSP x BN Map138.0099RGD
SHRSP x BN Map138.0099UniSTS
Cytogenetic Map13q11UniSTS
D13Got109  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21334,634,779 - 34,634,906 (+)MAPPERmRatBN7.2
Rnor_6.01339,472,624 - 39,472,750NCBIRnor6.0
Rnor_5.01344,593,852 - 44,593,978UniSTSRnor5.0
RGSC_v3.41335,574,614 - 35,574,740RGDRGSC3.4
RGSC_v3.41335,574,615 - 35,574,741UniSTSRGSC3.4
RGSC_v3.11335,588,579 - 35,588,705RGD
Celera1334,462,877 - 34,463,003UniSTS
RH 2.0 Map13186.6RGD
Cytogenetic Map13q11UniSTS
D13Got8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21336,155,723 - 36,155,834 (+)MAPPERmRatBN7.2
Rnor_6.01341,060,057 - 41,060,167NCBIRnor6.0
Rnor_5.01346,171,139 - 46,171,249UniSTSRnor5.0
RGSC_v3.41337,191,203 - 37,191,314RGDRGSC3.4
RGSC_v3.41337,191,204 - 37,191,314UniSTSRGSC3.4
RGSC_v3.11337,205,168 - 37,205,279RGD
RH 2.0 Map13206.1RGD
Cytogenetic Map13q11UniSTS
D13Got1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21336,139,191 - 36,139,409 (+)MAPPERmRatBN7.2
Rnor_6.01341,043,527 - 41,043,742NCBIRnor6.0
Rnor_5.01346,154,609 - 46,154,824UniSTSRnor5.0
RGSC_v3.41337,174,673 - 37,174,889RGDRGSC3.4
RGSC_v3.41337,174,674 - 37,174,889UniSTSRGSC3.4
RGSC_v3.11337,188,638 - 37,188,854RGD
Celera1335,953,479 - 35,953,694UniSTS
RH 2.0 Map13272.8RGD
Cytogenetic Map13q11UniSTS
D13Hmgc86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,407,990 - 35,408,317 (+)MAPPERmRatBN7.2
Rnor_6.01340,295,163 - 40,295,487NCBIRnor6.0
Rnor_5.01345,412,259 - 45,412,583UniSTSRnor5.0
RGSC_v3.41336,367,611 - 36,367,935UniSTSRGSC3.4
Celera1335,224,872 - 35,225,196UniSTS
Cytogenetic Map13q11UniSTS
D13Got236  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,391,098 - 35,391,279 (+)MAPPERmRatBN7.2
Rnor_6.01340,278,361 - 40,278,541NCBIRnor6.0
Rnor_5.01345,395,457 - 45,395,637UniSTSRnor5.0
RGSC_v3.41336,350,720 - 36,350,900UniSTSRGSC3.4
Celera1335,207,979 - 35,208,161UniSTS
Cytogenetic Map13q11UniSTS
D13Got260  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21334,926,908 - 34,927,163 (+)MAPPERmRatBN7.2
Rnor_6.01339,798,995 - 39,799,249NCBIRnor6.0
Rnor_5.01344,921,115 - 44,921,369UniSTSRnor5.0
RGSC_v3.41336,032,154 - 36,032,408UniSTSRGSC3.4
Celera1334,751,718 - 34,751,972UniSTS
Cytogenetic Map13q11UniSTS
RH132186  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,414,832 - 35,415,014 (+)MAPPERmRatBN7.2
Rnor_6.01340,302,184 - 40,302,365NCBIRnor6.0
Rnor_5.01345,419,280 - 45,419,461UniSTSRnor5.0
RGSC_v3.41336,374,451 - 36,374,632UniSTSRGSC3.4
Celera1335,231,739 - 35,231,920UniSTS
Cytogenetic Map13q11UniSTS
RH144136  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,637,760 - 35,637,865 (+)MAPPERmRatBN7.2
Rnor_6.01340,534,741 - 40,534,845NCBIRnor6.0
Rnor_5.01345,651,288 - 45,651,392UniSTSRnor5.0
RGSC_v3.41336,599,568 - 36,599,672UniSTSRGSC3.4
Celera1335,455,260 - 35,455,364UniSTS
Cytogenetic Map13q11UniSTS
AU048090  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,595,527 - 35,595,742 (+)MAPPERmRatBN7.2
Rnor_6.01340,493,048 - 40,493,262NCBIRnor6.0
Rnor_5.01345,609,509 - 45,609,723UniSTSRnor5.0
RGSC_v3.41336,556,748 - 36,556,962UniSTSRGSC3.4
Celera1335,413,031 - 35,413,245UniSTS
Cytogenetic Map13q11UniSTS
AU047695  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,400,392 - 35,400,556 (+)MAPPERmRatBN7.2
Rnor_6.01340,287,566 - 40,287,729NCBIRnor6.0
Rnor_5.01345,404,662 - 45,404,825UniSTSRnor5.0
RGSC_v3.41336,360,014 - 36,360,177UniSTSRGSC3.4
Celera1335,217,275 - 35,217,438UniSTS
Cytogenetic Map13q11UniSTS
AU047542  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01345,387,371 - 45,387,509NCBIRnor5.0
RGSC_v3.41336,342,630 - 36,342,774UniSTSRGSC3.4
Celera1335,199,889 - 35,200,033UniSTS
Cytogenetic Map13q11UniSTS
AU048615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21335,397,995 - 35,398,176 (+)MAPPERmRatBN7.2
Rnor_6.01340,285,258 - 40,285,438NCBIRnor6.0
Rnor_5.01345,402,354 - 45,402,534UniSTSRnor5.0
RGSC_v3.41336,357,617 - 36,357,797UniSTSRGSC3.4
Celera1335,214,878 - 35,215,058UniSTS
Cytogenetic Map13q11UniSTS
AU049248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21334,612,197 - 34,612,367 (+)MAPPERmRatBN7.2
Rnor_6.01339,450,042 - 39,450,211NCBIRnor6.0
Rnor_5.01344,571,270 - 44,571,439UniSTSRnor5.0
RGSC_v3.41335,552,033 - 35,552,202UniSTSRGSC3.4
Celera1334,440,294 - 34,440,461UniSTS
Cytogenetic Map13q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 60
Low 3 10 1 18 1 8 23 31 1
Below cutoff 30 22 15 1 15 8 8 6 12 7 8 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003527   ⟹   ENSRNOP00000003527
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1334,595,868 - 34,782,208 (-)Ensembl
Rnor_6.0 Ensembl1339,434,217 - 39,643,361 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103258   ⟹   ENSRNOP00000084617
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1334,595,868 - 35,413,631 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112799   ⟹   ENSRNOP00000083925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1334,595,868 - 36,269,292 (-)Ensembl
RefSeq Acc Id: NM_001012205   ⟹   NP_001012205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,596,378 - 36,269,292 (-)NCBI
Rnor_6.01339,434,215 - 41,173,706 (-)NCBI
Rnor_5.01344,555,443 - 46,284,894 (-)NCBI
RGSC_v3.41335,536,212 - 37,304,931 (-)RGD
Celera1334,424,493 - 36,082,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598873   ⟹   XP_017454362
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,584,420 - 35,413,483 (-)NCBI
Rnor_6.01339,430,590 - 40,300,186 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598874   ⟹   XP_017454363
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,584,420 - 35,412,790 (-)NCBI
Rnor_6.01339,430,590 - 40,299,971 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090946   ⟹   XP_038946874
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,584,420 - 36,269,619 (-)NCBI
RefSeq Acc Id: XM_039090947   ⟹   XP_038946875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,584,420 - 34,793,411 (-)NCBI
RefSeq Acc Id: XM_039090948   ⟹   XP_038946876
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21334,671,142 - 35,413,486 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001012205   ⟸   NM_001012205
- UniProtKB: Q6Q629 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017454362   ⟸   XM_017598873
- Peptide Label: isoform X1
- UniProtKB: Q0GLB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454363   ⟸   XM_017598874
- Peptide Label: isoform X3
- UniProtKB: Q0GLB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003527   ⟸   ENSRNOT00000003527
RefSeq Acc Id: XP_038946874   ⟸   XM_039090946
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946875   ⟸   XM_039090947
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038946876   ⟸   XM_039090948
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000083925   ⟸   ENSRNOT00000112799
RefSeq Acc Id: ENSRNOP00000084617   ⟸   ENSRNOT00000103258
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6Q629-F1-model_v2 AlphaFold Q6Q629 1-796 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306427 AgrOrtholog
BioCyc Gene G2FUF-18477 BioCyc
Ensembl Genes ENSRNOG00000002595 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003527 ENTREZGENE
  ENSRNOP00000003527.6 UniProtKB/TrEMBL
  ENSRNOP00000083925 ENTREZGENE
  ENSRNOP00000083925.1 UniProtKB/Swiss-Prot
  ENSRNOP00000084617 ENTREZGENE
  ENSRNOP00000084617.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003527 ENTREZGENE
  ENSRNOT00000003527.6 UniProtKB/TrEMBL
  ENSRNOT00000103258 ENTREZGENE
  ENSRNOT00000103258.1 UniProtKB/TrEMBL
  ENSRNOT00000112799 ENTREZGENE
  ENSRNOT00000112799.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dipeptidylpeptidase IV, N-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9B_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:363972 UniProtKB/Swiss-Prot
NCBI Gene 363972 ENTREZGENE
PANTHER INACTIVE DIPEPTIDYL PEPTIDASE 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DPPIV_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dpp10 PhenoGen
Superfamily-SCOP DPP6 N-terminal domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DPP10_RAT UniProtKB/Swiss-Prot
  F1LPW1_RAT UniProtKB/TrEMBL
  Q0GLB5 ENTREZGENE, UniProtKB/TrEMBL
  Q0GLB6 ENTREZGENE, UniProtKB/TrEMBL
  Q6Q629 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Dpp10  dipeptidyl peptidase like 10  Dpp10  dipeptidylpeptidase 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Dpp10  dipeptidylpeptidase 10  Dpp10_predicted  dipeptidylpeptidase 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dpp10_predicted  dipeptidylpeptidase 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED