Gene: KCND2 (potassium voltage-gated channel subfamily D member 2) Homo sapiens
Symbol: KCND2
Name: potassium voltage-gated channel subfamily D member 2
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA1044; KV4.2; MGC119702; MGC119703; OTTHUMP00000211253; potassium channel, voltage gated Shal related subfamily D, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; RK5; voltage-gated potassium channel Kv4.2; voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387120,273,638 - 120,750,333 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377119,913,689 - 120,390,387 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367119,700,958 - 120,177,623 (+)NCBINCBI36hg18NCBI36
Build 347119,507,672 - 119,984,338NCBI
Celera7114,723,245 - 115,199,902 (+)NCBI
Cytogenetic Map7q31.31NCBI
HuRef7114,276,961 - 114,753,560 (+)NCBIHuRef
CHM1_17119,847,044 - 120,323,690 (+)NCBICHM1_1
CRA_TCAGchr7v27119,308,832 - 119,785,474 (+)NCBI
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Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

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Nomenclature History
More on KCND2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
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RGD Object Information
RGD ID: 68574
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-02-05
Status: ACTIVE