Mtmr2 (myotubularin related protein 2)

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Gene: Mtmr2 (myotubularin related protein 2) Rattus norvegicus

Analyze

Symbol:

Mtmr2

Name:

myotubularin related protein 2

RGD ID:

1311865

Description:

Predicted to enable identical protein binding activity; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; and phosphatidylinositol-3-phosphate phosphatase activity. Involved in several processes, including dendritic spine maintenance; negative regulation of excitatory postsynaptic potential; and regulation of vesicle-mediated transport. Located in several cellular components, including dendritic spine; postsynaptic density; and synaptic vesicle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Orthologous to human MTMR2 (myotubularin related protein 2); INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC315422; myotubularin-related protein 2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MTMR2 (myotubularin related protein 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mtmr2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mtmr2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MTMR2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MTMR2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mtmr2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MTMR2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MTMR2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mtmr2 (myotubularin related protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MTMR1 (myotubularin related protein 1)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	MTMR2 (myotubularin related protein 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mtmr2 (myotubularin related protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mtmr2 (myotubularin related protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mtm-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YMR1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	mtm	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	10,617,993 - 10,670,724 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	10,617,993 - 10,668,172 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	14,604,331 - 14,654,971 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	8	12,902,057 - 12,952,697 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	8	10,878,541 - 10,929,074 (+)	NCBI	Rnor_WKY
Rnor_6.0	8	12,283,471 - 12,334,014 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	12,284,528 - 12,333,316 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	12,233,710 - 12,284,290 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	10,556,644 - 10,606,844 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	10,557,636 - 10,605,951 (+)	NCBI
Celera	8	12,118,312 - 12,168,683 (+)	NCBI		Celera
Cytogenetic Map	8	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ataxia telangiectasia (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type 4 (ISO)

Charcot-Marie-Tooth disease type 4B1 (ISO)

genetic disease (ISO)

intellectual disability (ISO)

mosaic variegated aneuploidy syndrome 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-nitropyrene (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

4-amino-2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (EXP)

bisphenol A (EXP,ISO)

butanal (ISO)

caffeine (ISO)

camptothecin (ISO)

coumarin (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

fenvalerate (EXP)

flutamide (EXP)

folic acid (ISO)

ivermectin (ISO)

methidathion (ISO)

methotrexate (ISO)

rotenone (ISO)

sarin (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

tamoxifen (ISO)

thioacetamide (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dendritic spine maintenance (IMP)

dephosphorylation (ISO)

myelin assembly (ISO)

myelination (ISO)

negative regulation of endocytosis (IMP)

negative regulation of excitatory postsynaptic potential (IMP)

negative regulation of myelination (ISO)

negative regulation of receptor catabolic process (IMP)

negative regulation of receptor internalization (IMP)

neuron development (ISO)

phosphatidylinositol dephosphorylation (ISO)

phosphatidylinositol metabolic process (ISO)

positive regulation of early endosome to late endosome transport (IMP)

regulation of phosphatidylinositol dephosphorylation (ISO)

Cellular Component

axon (IDA)

cytoplasm (ISO)

cytosol (IDA,ISO)

dendrite (IDA)

dendritic spine (IDA)

intracellular membrane-bounded organelle (ISO)

nucleus (ISO)

postsynaptic density (IDA)

synaptic membrane (IDA)

synaptic vesicle (IDA)

vacuolar membrane (ISO)

Molecular Function

identical protein binding (ISO)

phosphatidylinositol phosphate phosphatase activity (ISO)

phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity (IBA,ISO)

phosphatidylinositol-3-phosphate phosphatase activity (ISO)

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	The phosphoinositide 3-phosphatase MTMR2 interacts with PSD-95 and maintains excitatory synapses by modulating endosomal traffic.	Lee HW, etal., J Neurosci. 2010 Apr 21;30(16):5508-18. doi: 10.1523/JNEUROSCI.4283-09.2010.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12668758	PMID:12837694	PMID:16399794	PMID:16778019	PMID:16787938	PMID:18570454	PMID:19587293	PMID:21510942	PMID:22028665

Genomics

Comparative Map Data

Mtmr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	10,617,993 - 10,670,724 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	10,617,993 - 10,668,172 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	14,604,331 - 14,654,971 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	8	12,902,057 - 12,952,697 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	8	10,878,541 - 10,929,074 (+)	NCBI	Rnor_WKY
Rnor_6.0	8	12,283,471 - 12,334,014 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	12,284,528 - 12,333,316 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	12,233,710 - 12,284,290 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	10,556,644 - 10,606,844 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	10,557,636 - 10,605,951 (+)	NCBI
Celera	8	12,118,312 - 12,168,683 (+)	NCBI		Celera
Cytogenetic Map	8	q12	NCBI

MTMR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	95,832,880 - 95,924,107 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	11	95,821,766 - 95,925,315 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	95,566,044 - 95,657,271 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	95,205,694 - 95,296,920 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	95,205,693 - 95,296,920	NCBI
Celera	11	92,864,432 - 92,955,746 (-)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI
HuRef	11	91,631,843 - 91,723,157 (-)	NCBI		HuRef
CHM1_1	11	95,449,060 - 95,540,399 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	95,840,305 - 95,931,520 (-)	NCBI		T2T-CHM13v2.0

Mtmr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	13,660,397 - 13,720,192 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	13,659,706 - 13,717,777 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	13,747,260 - 13,808,896 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	13,748,410 - 13,806,481 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	13,553,625 - 13,610,925 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	13,498,807 - 13,556,194 (+)	NCBI		MGSCv36	mm8
Celera	9	11,027,704 - 11,084,917 (+)	NCBI		Celera
Cytogenetic Map	9	A1	NCBI

Mtmr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	693,743 - 750,154 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	693,743 - 764,377 (-)	NCBI	ChiLan1.0	ChiLan1.0

MTMR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	94,367,038 - 94,457,138 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	94,367,038 - 94,457,138 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	90,839,577 - 90,929,731 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

MTMR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	5,194,772 - 5,316,441 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	5,194,604 - 5,315,375 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	5,205,909 - 5,327,596 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	5,366,974 - 5,491,223 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	5,366,812 - 5,491,187 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	5,164,226 - 5,285,897 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	5,225,833 - 5,347,545 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	5,273,521 - 5,395,231 (+)	NCBI		UU_Cfam_GSD_1.0

Mtmr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	80,672,667 - 80,755,065 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936700	1,790,064 - 1,873,034 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936700	1,790,592 - 1,873,019 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTMR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	27,854,491 - 27,974,423 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	27,864,335 - 27,974,448 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	31,847,124 - 31,938,450 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTMR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	87,090,401 - 87,181,057 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	87,087,191 - 87,180,497 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	38,639,598 - 38,727,631 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mtmr2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	40,673,156 - 40,770,693 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mtmr2
218 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	81
Count of miRNA genes:	78
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000008566
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590084	Insglur5	Insulin/glucose ratio QTL 5	18.54	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	8	1	24597739	Rat
2317882	Alcrsp24	Alcohol response QTL 24	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	8	1	25902202	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2097640	47097640	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2097640	47097640	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2097640	47097640	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2097640	47097640	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat

Markers in Region

RH128887

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	10,667,902 - 10,668,088 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	12,333,745 - 12,333,930	NCBI	Rnor6.0
Rnor_5.0	8	12,284,021 - 12,284,206	UniSTS	Rnor5.0
RGSC_v3.4	8	10,606,577 - 10,606,762	UniSTS	RGSC3.4
Celera	8	12,168,416 - 12,168,601	UniSTS
RH 3.4 Map	14	153.87	UniSTS
Cytogenetic Map	8	q11	UniSTS

RH129185

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	10,667,908 - 10,668,092 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	12,333,751 - 12,333,934	NCBI	Rnor6.0
Rnor_5.0	8	12,284,027 - 12,284,210	UniSTS	Rnor5.0
RGSC_v3.4	8	10,606,583 - 10,606,766	UniSTS	RGSC3.4
Celera	8	12,168,422 - 12,168,605	UniSTS
RH 3.4 Map	8	54.9	UniSTS
Cytogenetic Map	8	q11	UniSTS

RH129330

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	10,667,910 - 10,668,092 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	12,333,753 - 12,333,934	NCBI	Rnor6.0
Rnor_5.0	8	12,284,029 - 12,284,210	UniSTS	Rnor5.0
RGSC_v3.4	8	10,606,585 - 10,606,766	UniSTS	RGSC3.4
Celera	8	12,168,424 - 12,168,605	UniSTS
RH 3.4 Map	9	797.7	UniSTS
Cytogenetic Map	8	q11	UniSTS

RH129379

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	10,667,985 - 10,668,142 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	12,333,828 - 12,333,984	NCBI	Rnor6.0
Rnor_5.0	8	12,284,104 - 12,284,260	UniSTS	Rnor5.0
RGSC_v3.4	8	10,606,660 - 10,606,816	UniSTS	RGSC3.4
Celera	8	12,168,499 - 12,168,655	UniSTS
Cytogenetic Map	8	q11	UniSTS

RH129424

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	10,667,993 - 10,668,145 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	12,333,836 - 12,333,987	NCBI	Rnor6.0
Rnor_5.0	8	12,284,112 - 12,284,263	UniSTS	Rnor5.0
RGSC_v3.4	8	10,606,668 - 10,606,819	UniSTS	RGSC3.4
Celera	8	12,168,507 - 12,168,658	UniSTS
RH 3.4 Map	8	72.58	UniSTS
Cytogenetic Map	8	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ760741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000008566 ⟹ ENSRNOP00000008566

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	10,618,767 - 10,668,172 (+)	Ensembl
Rnor_6.0 Ensembl	8	12,284,528 - 12,333,316 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096205 ⟹ ENSRNOP00000082304

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	10,617,993 - 10,668,170 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000098206 ⟹ ENSRNOP00000080784

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	10,619,215 - 10,668,172 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106341 ⟹ ENSRNOP00000090683

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	10,617,993 - 10,668,170 (+)	Ensembl

RefSeq Acc Id:

NM_001108123 ⟹ NP_001101593

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	10,617,993 - 10,668,170 (+)	NCBI
Rnor_6.0	8	12,283,675 - 12,334,012 (+)	NCBI
Rnor_5.0	8	12,233,710 - 12,284,290 (+)	NCBI
RGSC_v3.4	8	10,556,644 - 10,606,844 (+)	RGD
Celera	8	12,118,312 - 12,168,683 (+)	RGD

Sequence:

show sequence

TCTTTTATGAGTTTAACAGATTCTTCCTCTTTCTCACTTCAATACTTAGTACGCCTTACAGGGT
GGTGTCAAAGTGCTTATCAGTTACAGACACACTTCCCGGCCACTTTAACCCATACTCTTGTCAC
AGGAGGCCTGAAAACTTCAACTCCATTCTCACTTTCCTTTGTATAACGCTGTTTAGAGGTGTAA
ACATTAGAAATGTAATTTTCAGCGTTTTCCCTCCCCTCCCCCGGTGGGTGTTATTACCTTTCTC
CTACCAACTACTTGTTAATGGTCTGCCATCCTTTAGTTTTCTTTCTTTAACAGTAACCATTTAT
TAAATTTGTTAGGTTGTTTATATATGCGCACCCATTGACTACAGCCTGAGCGCTTCTTAAGCAG
GCATTGCTTTAGGCATTTTACATTTATCAACACATTCTGTGATGCTAACACACGTACACAGAAG
GAAGCAAATGTAAACGCAAGGTAACTGGAGGCCGTGGAATCTGAATCTGCTTATCTTCACTGTG
ACCTCTACAAAATAGGTTCTCACATCACGTATGACATACGTTTCACTATTTCTAACCTCATCCT
TAAATACTTTTACTCCTTAATCTCCCACCTCACCCCCTCATCCCATAGGCCGCCCACATTCCTC
TCATTTCCCTCGAGTCAGCCGCTTCCAAGCCTTCACATCTTGTCTCTTTTCTTTGACGTACTGG
TGTCCTCTTCCTTATGAAGGCTTTCCTTGTAGCTGAAAGTATCCACCAGACTCTTAGGCTGCCT
CTCACTGGGTGGCCAGGGCGCGTGCGCACCGCACCGCTTTGTAGAGCCAAGGGGGCCCGACTCC
CAACAGCCCCCGCGCGCAGTGCAGGCTGGGGGAACATGGCCGCTTCCGGTCTCGCAGTCTTCCT
GGCGAGGGGTTGACAGCGGCTGCGGCCCTGCGCGCTCCTCCCTCTGCATCTCGCGCCGGCGGCC
GCGGAGGGCGCAGCGGCCTCCTGTTCTCGCGCCATGGAGAAGAGCTCGAGCTGCGAGAGTCTTG
GCGCGCAGCTCCCGGCGGCAAGGCTTCCCAGCGAGGACTCACTGTCCAGTGCTTCCACTTCTCA
TTCAGAGAACTCGGTTCATACCAAATCAGTTTCTGCTATATCATCAGATTCTATTTCAACCTCT
GCAGACAACTTCTCTCCTGATCTGAGGGTCCTGAGGGAGGCAAACAAATTAGCAGAAATGGAGG
AACCAGCCCTGCTTCCAGGAGAGAACATCAAAGATATGGCCAAAGATGTGACTTACATATGTCC
GTTCACTGGTGCTGTACGAGGGACGCTGACTGTCACAAATTACAGATTATATTTCAAGAGCATG
GAACGGGACCCTCCGTTTGTTCTAGATGCTTCTCTTGGGGTGATAAGTAGAGTAGAAAAAATCG
GTGGTGCATCTAGCCGTGGTGAAAATTCTTATGGCCTGGAAACGGTGTGCAAGGATATCAGGAA
TTTACGATTTGCTCATAAACCAGAGGGGCGAACAAGAAGATCAATATTTGAGAATCTAATGAAA
TATGCATTTCCTGTGTCTAACGGCTTGCCTCTTTTTGCTTTTGAGTATAAAGAAGTATTCCCTG
AAAATGGGTGGAAACTGTATGACCCCCTTCTAGAGTACAGAAGACAGGGGATTCCAAATGAAAG
CTGGAGAATAACAAAGGTCAATGAACGCTATGAACTCTGTGACACATATCCTGCCCTCTTGGCC
GTGCCAGCAAACATTCCTGATGAGGAACTCAAGAGAGTGGCATCCTTCAGGTCCCGGGGCCGGA
TCCCAGTTTTATCATGGATTCATCCTGAAAGTCAGGCCACAGTCACCCGCTGCAGCCAGCCCAT
GGTTGGAGTGAGTGGGAAGCGCAGCAAAGAGGATGAGAAGTATCTTCAGGCCATCATGGACTCC
AATGCCCAGTCTCACAAAATATTTATATTTGATGCTCGGCCAAGTGTCAATGCTGTTGCCAATA
AGGCAAAGGGCGGAGGTTATGAAAGTGAAGACGCTTATCAAAATGCAGAACTCGTTTTCCTGGA
CATTCATAATATCCATGTTATGAGAGAATCATTACGGAAGCTTAAGGAGATTGTGTACCCCAAC
ATTGAGGAAACTCACTGGTTGTCTAACTTAGAATCTACACACTGGCTGGAACACATCAAGCTCA
TTCTTGCGGGGGCTCTTCGGATTGCTGACAAGGTGGAGTCTGGGAAGACGTCTGTGGTGGTGCA
CTGCAGTGATGGGTGGGATCGCACAGCTCAGCTCACGTCCCTGGCCATGCTTATGCTGGATGGA
TACTATCGAACCATACGAGGATTTGAAGTCCTTGTGGAGAAAGAGTGGCTAAGCTTTGGACATC
GATTCCAACTAAGAGTTGGCCATGGCGATAAGAACCATGCTGATGCAGACCGATCACCTGTTTT
CCTTCAGTTCATTGACTGTGTCTGGCAGATGACAAGACAGTTCCCTACCGCATTTGAATTCAAT
GAGTATTTTCTCATTACCATCCTGGACCACTTGTACAGCTGTCTATTTGGGACATTCCTCTGTA
ACAGTGAACAGCAGAGGGGAAAAGAGAATCTTCCTAAGAAGACAGTGTCACTGTGGTCCTATAT
AAACAGCCAGCTGGAAGACTTCACTAATCCTCTTTTTGGGAGCTACTCCAATCATGTCCTTTAC
CCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGGTGGGCTATTATATAAGGTGGAACCCCCGGA
TGAAACCACAGGAACCTATCCACAGCAGATACAAAGAACTTCTTGCCAAAAGAACAGAGCTTCA
AAGAAAAGTAGAGGAACTTCAGAGAGAAATTTCCAACCGCTCAACCTCCTCTTCAGAGAGAGCC
AGCTCTCCCGCACAGTGTGTGACTCCTGTCCAAACTGTTGTATGAAAGAACTAGGCATGTTGCC
AGGAACTTGACATTACAGCACCTTATGCGTAGAAAGCCTTCTGTGTTTTAAACCCATCTGTGGG
AGAATCCTTCAGATGCTGTATTTATTTCAAATCTCTCTTAGATGAGTTTAGAAACATAGCGGTG
CAAGTGACAATGAAGATGATCTCATTTGTAATTAAAGATGACACTAATCTGAAGTCCCCCAAAG
AATACTAAAGTACTGCAGTCCTGTGCTCACCCTGGGAGCCAGCTTTTCATTTAAAGCTGTCTTA
AAAGCACTGCTAAGAGCTCTAGGTGGGGAGAAAAGCAAGGCTGTTCTTGCACCTGAGAGCATAC
ATACCAAGCCTTGATCTCAACTGTCCCATTTTTTGTGGTATTTAATATAGTAAAAAGCATTGTC
TTAAAATTGTTACAGCATAGTAGTAGTTGGAAATTGCTGCTGACATTGTAATTAGCGTATTTTC
AACAGCAGTTAGGAAACGATGCCTTATATATTTGCTTTGGGGGTGAAGGGACAAAGTAACTGTC
ATCCAGGAATTCAAAAATATTCTTTCCCGTCAGCCAATTTCCATTTGTATGTTGATCACAAATA
CCACAGACACTTTAAAACCTTACCATTACTCCACTTATCTTAATGCTGATTGGCAAGTTTTAAA
AACTTAAGTGCTATATTTAAATTTCACATGAACATTTTATCAAAGACCACTCTGCATGTGAGTT
AGTCTCGGTGCCAGCAAGTAAAGCCTCGCTTCTCTGCTCGCCTGAGTTGGGTGCTGGTGTGAAC
AGTTGACTCCTGGTGTCTGTTTCACTCTGTATAAGAGCCATATGTAATGTACTGTAACAAACGA
GCTTCTTACCACTTGGTCTTTTAATTAAATGACTTCAAACTT

hide sequence

RefSeq Acc Id:

XM_006242521 ⟹ XP_006242583

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	10,618,080 - 10,670,724 (+)	NCBI
Rnor_6.0	8	12,283,471 - 12,334,014 (+)	NCBI
Rnor_5.0	8	12,233,710 - 12,284,290 (+)	NCBI

Sequence:

show sequence

TTAGAGAGATTCCTCTAGTACTGTCCTTCCTGTGCCCTGAGTAACATAAAGTCATGGTATTAAC
GTTCTCCCTTCACCCAGTTCCTGTCGCTTATCTCATTCCATCCCCACACTCCCTTCCTGCTCTG
CAAGGGAATATGAAGGCGCACACAGGAGAGAAGTCTGTTCTCTATGTTGCACCAGGCATTCAGC
AGTGTCTCTAATTCTTTTATGAGTTTAACAGATTCTTCCTCTTTCTCACTTCAATACTTAGTAC
GCCTTACAGGGTGGTGTCAAAGTGCTTATCAGTTACAGACACACTTCCCGGCCACTTTAACCCA
TACTCTTGTCACAGGAGGCCTGAAAACTTCAACTCCATTCTCACTTTCCTTTGTATAACGCTGT
TTAGAGGTGTAAACATTAGAAATGTAATTTTCAGCGTTTTCCCTCCCCTCCCCCGGTGGGTGTT
ATTACCTTTCTCCTACCAACTACTTGTTAATGGTCTGCCATCCTTTAGTTTTCTTTCTTTAACA
GTAACCATTTATTAAATTTGTTAGGTTGTTTATATATGCGCACCCATTGACTACAGCCTGAGCG
CTTCTTAAGCAGGCATTGCTTTAGGCATTTTACATTTATCAACACATTCTGTGATGCTAACACA
CGTACACAGAAGGAAGCAAATGTAAACGCAAGGTAACTGGAGGCCGTGGAATCTGAATCTGCTT
ATCTTCACTGTGACCTCTACAAAATAGGTTCTCACATCACGTATGACATACGTTTCACTATTTC
TAACCTCATCCTTAAATACTTTTACTCCTTAATCTCCCACCTCACCCCCTCATCCCATAGGCCG
CCCACATTCCTCTCATTTCCCTCGAGTCAGCCGCTTCCAAGCCTTCACATCTTGTCTCTTTTCT
TTGACGTACTGGTGTCCTCTTCCTTATGAAGGCTTTCCTTGTAGCTGAAAGTATCCACCAGACT
CTTAGGCTGCCTCTCACTGGGTGGCCAGGGCGCGTGCGCACCGCACCGCTTTGTAGAGCCAAGG
GGGCCCGACTCCCAACAGCCCCCGCGCGCAGTGCAGGCTGGGGGAACATGGCCGCTTCCGGTCT
CGCAGTCTTCCTGGCGAGGGGTTGACAGCGGCTGCGGCCCTGCGCGCTCCTCCCTCTGCATCTC
GCGCCGGCGGCCGCGGAGGGCGCAGCGGCCTCCTGTTCTCGCGCCATGGAGAAGAGCTCGAGCT
GCGAGAGTCTTGGCGCGCAGCTCCCGGCGGCAAGGCTTCCCAGCGAGGACTCACTGTCCAGTTC
ATGTGTTAAGAACCATTGACATTTGAAGATCGTCAGAACTGAAGATAAAACATCTCAAAAAGTA
TAATTGCTTCCACTTCTCATTCAGAGAACTCGGTTCATACCAAATCAGTTTCTGCTATATCATC
AGATTCTATTTCAACCTCTGCAGACAACTTCTCTCCTGATCTGAGGGTCCTGAGGGAGGCAAAC
AAATTAGCAGAAATGGAGGAACCAGCCCTGCTTCCAGGAGAGAACATCAAAGATATGGCCAAAG
ATGTGACTTACATATGTCCGTTCACTGGTGCTGTACGAGGGACGCTGACTGTCACAAATTACAG
ATTATATTTCAAGAGCATGGAACGGGACCCTCCGTTTGTTCTAGATGCTTCTCTTGGGGTGATA
AGTAGAGTAGAAAAAATCGGTGGTGCATCTAGCCGTGGTGAAAATTCTTATGGCCTGGAAACGG
TGTGCAAGGATATCAGGAATTTACGATTTGCTCATAAACCAGAGGGGCGAACAAGAAGATCAAT
ATTTGAGAATCTAATGAAATATGCATTTCCTGTGTCTAACGGCTTGCCTCTTTTTGCTTTTGAG
TATAAAGAAGTATTCCCTGAAAATGGGTGGAAACTGTATGACCCCCTTCTAGAGTACAGAAGAC
AGGGGATTCCAAATGAAAGCTGGAGAATAACAAAGGTCAATGAACGCTATGAACTCTGTGACAC
ATATCCTGCCCTCTTGGCCGTGCCAGCAAACATTCCTGATGAGGAACTCAAGAGAGTGGCATCC
TTCAGGTCCCGGGGCCGGATCCCAGTTTTATCATGGATTCATCCTGAAAGTCAGGCCACAGTCA
CCCGCTGCAGCCAGCCCATGGTTGGAGTGAGTGGGAAGCGCAGCAAAGAGGATGAGAAGTATCT
TCAGGCCATCATGGACTCCAATGCCCAGTCTCACAAAATATTTATATTTGATGCTCGGCCAAGT
GTCAATGCTGTTGCCAATAAGGCAAAGGGCGGAGGTTATGAAAGTGAAGACGCTTATCAAAATG
CAGAACTCGTTTTCCTGGACATTCATAATATCCATGTTATGAGAGAATCATTACGGAAGCTTAA
GGAGATTGTGTACCCCAACATTGAGGAAACTCACTGGTTGTCTAACTTAGAATCTACACACTGG
CTGGAACACATCAAGCTCATTCTTGCGGGGGCTCTTCGGATTGCTGACAAGGTGGAGTCTGGGA
AGACGTCTGTGGTGGTGCACTGCAGTGATGGGTGGGATCGCACAGCTCAGCTCACGTCCCTGGC
CATGCTTATGCTGGATGGATACTATCGAACCATACGAGGATTTGAAGTCCTTGTGGAGAAAGAG
TGGCTAAGCTTTGGACATCGATTCCAACTAAGAGTTGGCCATGGCGATAAGAACCATGCTGATG
CAGACCGATCACCTGTTTTCCTTCAGTTCATTGACTGTGTCTGGCAGATGACAAGACAGTTCCC
TACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATCCTGGACCACTTGTACAGCTGTCTA
TTTGGGACATTCCTCTGTAACAGTGAACAGCAGAGGGGAAAAGAGAATCTTCCTAAGAAGACAG
TGTCACTGTGGTCCTATATAAACAGCCAGCTGGAAGACTTCACTAATCCTCTTTTTGGGAGCTA
CTCCAATCATGTCCTTTACCCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGGTGGGCTATTAT
ATAAGGTGGAACCCCCGGATGAAACCACAGGAACCTATCCACAGCAGATACAAAGAACTTCTTG
CCAAAAGAACAGAGCTTCAAAGAAAAGTAGAGGAACTTCAGAGAGAAATTTCCAACCGCTCAAC
CTCCTCTTCAGAGAGAGCCAGCTCTCCCGCACAGTGTGTGACTCCTGTCCAAACTGTTGTATGA
AAGAACTAGGCATGTTGCCAGGAACTTGACATTACAGCACCTTATGCGTAGAAAGCCTTCTGTG
TTTTAAACCCATCTGTGGGAGAATCCTTCAGATGCTGTATTTATTTCAAATCTCTCTTAGATGA
GTTTAGAAACATAGCGGTGCAAGTGACAATGAAGATGATCTCATTTGTAATTAAAGATGACACT
AATCTGAAGTCCCCCAAAGAATACTAAAGTACTGCAGTCCTGTGCTCACCCTGGGAGCCAGCTT
TTCATTTAAAGCTGTCTTAAAAGCACTGCTAAGAGCTCTAGGTGGGGAGAAAAGCAAGGCTGTT
CTTGCACCTGAGAGCATACATACCAAGCCTTGATCTCAACTGTCCCATTTTTTGTGGTATTTAA
TATAGTAAAAAGCATTGTCTTAAAATTGTTACAGCATAGTAGTAGTTGGAAATTGCTGCTGACA
TTGTAATTAGCGTATTTTCAACAGCAGTTAGGAAACGATGCCTTATATATTTGCTTTGGGGGTG
AAGGGACAAAGTAACTGTCATCCAGGAATTCAAAAATATTCTTTCCCGTCAGCCAATTTCCATT
TGTATGTTGATCACAAATACCACAGACACTTTAAAACCTTACCATTACTCCACTTATCTTAATG
CTGATTGGCAAGTTTTAAAAACTTAAGTGCTATATTTAAATTTCACATGAACATTTTATCAAAG
ACCACTCTGCATGTGAGTTAGTCTCGGTGCCAGCAAGTAAAGCCTCGCTTCTCTGCTCGCCTGA
GTTGGGTGCTGGTGTGAACAGTTGACTCCTGGTGTCTGTTTCACTCTGTATAAGAGCCATATGT
AATGTACTGTAACAAACGAGCTTCTTACCACTTGGTCTTTTAATTAAATGACTTCAAACTTTA

hide sequence

RefSeq Acc Id:

XM_006242522 ⟹ XP_006242584

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	10,631,752 - 10,670,724 (+)	NCBI
Rnor_6.0	8	12,296,569 - 12,334,014 (+)	NCBI
Rnor_5.0	8	12,233,710 - 12,284,290 (+)	NCBI

Sequence:

show sequence

CCCACGAAATAGAGTCCTGGTGTTCATTTGTTTTTTTGTGCTTGCTGAGATTAGAGAGCTGCCC
AGGTCAAAGCTTACTGACTAAGCTGACTACCCTGCCAGTTAACCTGAGATACATTCTGACAAAG
TTCACCTTAGAATATTTTTCTCAATTAACTGATACACATAAGAAAGTTTTCCTTGTAGGCCACA
CTTGTGAGTCTACTTAAGCACTAATTTAAATTGTTTGCTGAATGCAGATTGCTGAATAAAATGG
ATTTTGAGGAGTTGTTTTAGGACTGATGTAGCTACTGGGTTCGACCTGAAGCTCAGGAGTCCCT
GCTCCTGGCCTCACCCCACCTCATGTTGACATTCATTTTGATTACAGTACATTGGTGTTTACTG
GTTTTGTTAAACTTCTAAATATGATCTTTGCAAAACCTTCTGTGGGGGAAAGTCTTCTAAGCTG
TTATCAGTATAAATCGGTTCAGATTTTTATTGGAATTAACATCACATGCACTGAACTGATCTGG
AAATAAAATACTTACAATCTAACCATGTGTCCTGGATGACCTGTTCTTCCTTGGCATTTTCCAA
AAGTGCCAATAAACACCAGCCAAGGCTAGCAGAGCTCAGATTCATCTTGTTCTCTGAGTGAAGA
CTCTCATCTCTGTCAGTTCCCTTGATAAAACATCAATTCTGACACTCTTGTCCTTTACATTGGT
TAAGTTTAAACCCATAGATCTGGCATGGCATTTAAAAGAGATTAAACATGAACATTACCATGTT
CTGGTGAAGTTGTTTTTCTGATTTGGAGACAGATATTCTGACAGTAGGTTTTTGTTTTATGAAA
CACACTGCAGGCCTTTTATTACTTTTTTAAGTAAATTTTTCAACAGAATGACTAACAGGCACAA
GCACATACAGTGCTTAGGAAGAACACTGCAGTCCATTGTGTGAGTGCTGAGAACAAAATTTGCA
TTCCTAGAAAAATTTTCTTCCAATCACAATTCAGAAGGCATTCTTTAATATTCATGGACAGATG
ACATTAATAACCGGAGAACACTCAGAAAGCACCTCTTCGTTTCATGGGATATTCAACAGAAATT
GAATTGGCAGTGAAAAGAGCTGTTTAAACAAAGCAAGTGGTTTAGATCTCACTGTAACAACTGT
GGCCAGCTGCAGACTGGGAGTAGAAGAAGCATGGCTGATCCTGCACCCTCTTGAGACTTGTTCA
CTAGGAGTGTGAAAATGCTTCCACTTCTCATTCAGAGAACTCGGTTCATACCAAATCAGTTTCT
GCTATATCATCAGATTCTATTTCAACCTCTGCAGACAACTTCTCTCCTGATCTGAGGGTCCTGA
GGGAGGCAAACAAATTAGCAGAAATGGAGGAACCAGCCCTGCTTCCAGGAGAGAACATCAAAGA
TATGGCCAAAGATGTGACTTACATATGTCCGTTCACTGGTGCTGTACGAGGGACGCTGACTGTC
ACAAATTACAGATTATATTTCAAGAGCATGGAACGGGACCCTCCGTTTGTTCTAGATGCTTCTC
TTGGGGTGATAAGTAGAGTAGAAAAAATCGGTGGTGCATCTAGCCGTGGTGAAAATTCTTATGG
CCTGGAAACGGTGTGCAAGGATATCAGGAATTTACGATTTGCTCATAAACCAGAGGGGCGAACA
AGAAGATCAATATTTGAGAATCTAATGAAATATGCATTTCCTGTGTCTAACGGCTTGCCTCTTT
TTGCTTTTGAGTATAAAGAAGTATTCCCTGAAAATGGGTGGAAACTGTATGACCCCCTTCTAGA
GTACAGAAGACAGGGGATTCCAAATGAAAGCTGGAGAATAACAAAGGTCAATGAACGCTATGAA
CTCTGTGACACATATCCTGCCCTCTTGGCCGTGCCAGCAAACATTCCTGATGAGGAACTCAAGA
GAGTGGCATCCTTCAGGTCCCGGGGCCGGATCCCAGTTTTATCATGGATTCATCCTGAAAGTCA
GGCCACAGTCACCCGCTGCAGCCAGCCCATGGTTGGAGTGAGTGGGAAGCGCAGCAAAGAGGAT
GAGAAGTATCTTCAGGCCATCATGGACTCCAATGCCCAGTCTCACAAAATATTTATATTTGATG
CTCGGCCAAGTGTCAATGCTGTTGCCAATAAGGCAAAGGGCGGAGGTTATGAAAGTGAAGACGC
TTATCAAAATGCAGAACTCGTTTTCCTGGACATTCATAATATCCATGTTATGAGAGAATCATTA
CGGAAGCTTAAGGAGATTGTGTACCCCAACATTGAGGAAACTCACTGGTTGTCTAACTTAGAAT
CTACACACTGGCTGGAACACATCAAGCTCATTCTTGCGGGGGCTCTTCGGATTGCTGACAAGGT
GGAGTCTGGGAAGACGTCTGTGGTGGTGCACTGCAGTGATGGGTGGGATCGCACAGCTCAGCTC
ACGTCCCTGGCCATGCTTATGCTGGATGGATACTATCGAACCATACGAGGATTTGAAGTCCTTG
TGGAGAAAGAGTGGCTAAGCTTTGGACATCGATTCCAACTAAGAGTTGGCCATGGCGATAAGAA
CCATGCTGATGCAGACCGATCACCTGTTTTCCTTCAGTTCATTGACTGTGTCTGGCAGATGACA
AGACAGTTCCCTACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATCCTGGACCACTTGT
ACAGCTGTCTATTTGGGACATTCCTCTGTAACAGTGAACAGCAGAGGGGAAAAGAGAATCTTCC
TAAGAAGACAGTGTCACTGTGGTCCTATATAAACAGCCAGCTGGAAGACTTCACTAATCCTCTT
TTTGGGAGCTACTCCAATCATGTCCTTTACCCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGG
TGGGCTATTATATAAGGTGGAACCCCCGGATGAAACCACAGGAACCTATCCACAGCAGATACAA
AGAACTTCTTGCCAAAAGAACAGAGCTTCAAAGAAAAGTAGAGGAACTTCAGAGAGAAATTTCC
AACCGCTCAACCTCCTCTTCAGAGAGAGCCAGCTCTCCCGCACAGTGTGTGACTCCTGTCCAAA
CTGTTGTATGAAAGAACTAGGCATGTTGCCAGGAACTTGACATTACAGCACCTTATGCGTAGAA
AGCCTTCTGTGTTTTAAACCCATCTGTGGGAGAATCCTTCAGATGCTGTATTTATTTCAAATCT
CTCTTAGATGAGTTTAGAAACATAGCGGTGCAAGTGACAATGAAGATGATCTCATTTGTAATTA
AAGATGACACTAATCTGAAGTCCCCCAAAGAATACTAAAGTACTGCAGTCCTGTGCTCACCCTG
GGAGCCAGCTTTTCATTTAAAGCTGTCTTAAAAGCACTGCTAAGAGCTCTAGGTGGGGAGAAAA
GCAAGGCTGTTCTTGCACCTGAGAGCATACATACCAAGCCTTGATCTCAACTGTCCCATTTTTT
GTGGTATTTAATATAGTAAAAAGCATTGTCTTAAAATTGTTACAGCATAGTAGTAGTTGGAAAT
TGCTGCTGACATTGTAATTAGCGTATTTTCAACAGCAGTTAGGAAACGATGCCTTATATATTTG
CTTTGGGGGTGAAGGGACAAAGTAACTGTCATCCAGGAATTCAAAAATATTCTTTCCCGTCAGC
CAATTTCCATTTGTATGTTGATCACAAATACCACAGACACTTTAAAACCTTACCATTACTCCAC
TTATCTTAATGCTGATTGGCAAGTTTTAAAAACTTAAGTGCTATATTTAAATTTCACATGAACA
TTTTATCAAAGACCACTCTGCATGTGAGTTAGTCTCGGTGCCAGCAAGTAAAGCCTCGCTTCTC
TGCTCGCCTGAGTTGGGTGCTGGTGTGAACAGTTGACTCCTGGTGTCTGTTTCACTCTGTATAA
GAGCCATATGTAATGTACTGTAACAAACGAGCTTCTTACCACTTGGTCTTTTAATTAAATGACT
TCAAACTTTA

hide sequence

RefSeq Acc Id:

XM_039081338 ⟹ XP_038937266

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	10,617,993 - 10,670,724 (+)	NCBI

RefSeq Acc Id:

XM_039081339 ⟹ XP_038937267

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	10,619,130 - 10,670,724 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101593	(Get FASTA)	NCBI Sequence Viewer
	XP_006242583	(Get FASTA)	NCBI Sequence Viewer
	XP_006242584	(Get FASTA)	NCBI Sequence Viewer
	XP_038937266	(Get FASTA)	NCBI Sequence Viewer
	XP_038937267	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL78490	(Get FASTA)	NCBI Sequence Viewer
	EDL78491	(Get FASTA)	NCBI Sequence Viewer
	EDL78492	(Get FASTA)	NCBI Sequence Viewer
	EDL78493	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001101593 ⟸ NM_001108123

- UniProtKB:

D3ZA31 (UniProtKB/TrEMBL), A0A8I5ZTB8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEKSSSCESLGAQLPAARLPSEDSLSSASTSHSENSVHTKSVSAISSDSISTSADNFSPDLRVL
REANKLAEMEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDAS
LGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPL
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKVNERYELCDTYPALLAVPANIPDEELK
RVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFD
ARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLE
STHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVL
VEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHL
YSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLFGSYSNHVLYPVASMRHLELW
VGYYIRWNPRMKPQEPIHSRYKELLAKRTELQRKVEELQREISNRSTSSSERASSPAQCVTPVQ
TVV

hide sequence

RefSeq Acc Id:	XP_006242583 ⟸ XM_006242521
- Peptide Label:	isoform X2
- UniProtKB:	D3ZA31 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVISRVE KIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEV FPENGWKLYDPLLEYRRQGIPNESWRITKVNERYELCDTYPALLAVPANIPDEELKRVASFRSR GRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAV ANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHI KLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTF LCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLFGSYSNHVLYPVASMRHLELWVGYYIRWN PRMKPQEPIHSRYKELLAKRTELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV hide sequence

RefSeq Acc Id:	XP_006242584 ⟸ XM_006242522
- Peptide Label:	isoform X2
- UniProtKB:	D3ZA31 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVISRVE KIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEV FPENGWKLYDPLLEYRRQGIPNESWRITKVNERYELCDTYPALLAVPANIPDEELKRVASFRSR GRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAV ANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHI KLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTF LCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLFGSYSNHVLYPVASMRHLELWVGYYIRWN PRMKPQEPIHSRYKELLAKRTELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV hide sequence

RefSeq Acc Id:

ENSRNOP00000008566 ⟸ ENSRNOT00000008566

RefSeq Acc Id:	XP_038937266 ⟸ XM_039081338
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZTB8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937267 ⟸ XM_039081339
- Peptide Label:	isoform X2
- UniProtKB:	D3ZA31 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000082304 ⟸ ENSRNOT00000096205

RefSeq Acc Id:

ENSRNOP00000080784 ⟸ ENSRNOT00000098206

RefSeq Acc Id:

ENSRNOP00000090683 ⟸ ENSRNOT00000106341

Protein Domains

Myotubularin phosphatase Tyrosine specific protein phosphatases

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZA31-F1-model_v2	AlphaFold	D3ZA31	1-643	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695742

Promoter ID:

EPDNEW_R6265

Type:

initiation region

Name:

Mtmr2_1

Description:

myotubularin related protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	12,284,518 - 12,284,578	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311865	AgrOrtholog
BioCyc Gene	G2FUF-31707	BioCyc
Ensembl Genes	ENSRNOG00000005923	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000008566	ENTREZGENE
	ENSRNOP00000008566.3	UniProtKB/TrEMBL
	ENSRNOP00000080784	ENTREZGENE
	ENSRNOP00000080784.1	UniProtKB/TrEMBL
	ENSRNOP00000082304	ENTREZGENE
	ENSRNOP00000082304.1	UniProtKB/TrEMBL
	ENSRNOP00000090683.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008566	ENTREZGENE
	ENSRNOT00000008566.6	UniProtKB/TrEMBL
	ENSRNOT00000096205	ENTREZGENE
	ENSRNOT00000096205.1	UniProtKB/TrEMBL
	ENSRNOT00000098206	ENTREZGENE
	ENSRNOT00000098206.1	UniProtKB/TrEMBL
	ENSRNOT00000106341.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
InterPro	GRAM	UniProtKB/TrEMBL
	Myotub-related	UniProtKB/TrEMBL
	Myotubularin_fam	UniProtKB/TrEMBL
	PH_like_dom	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	Tyr/Dual-sp_Pase	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/TrEMBL
KEGG Report	rno:315422	UniProtKB/TrEMBL
NCBI Gene	315422	ENTREZGENE
PANTHER	MYOTUBULARIN-RELATED PROTEIN 2	UniProtKB/TrEMBL
	PTHR10807	UniProtKB/TrEMBL
Pfam	GRAM	UniProtKB/TrEMBL
	Myotub-related	UniProtKB/TrEMBL
PhenoGen	Mtmr2	PhenoGen
PROSITE	PPASE_MYOTUBULARIN	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
SMART	GRAM	UniProtKB/TrEMBL
	PTPc_motif	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF52799	UniProtKB/TrEMBL
UniProt	A0A8I5ZQN1_RAT	UniProtKB/TrEMBL
	A0A8I5ZTB8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ABE9_RAT	UniProtKB/TrEMBL
	D3ZA31	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Mtmr2	myotubularin related protein 2	Mtmr2_predicted	myotubularin related protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Mtmr2_predicted	myotubularin related protein 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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