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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoconazole
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Accession:CHEBI:82865 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-isoconazole. A broad-spectrum antibacterial drug used (as its nitrate salt) for treatment of dermatomycoses.
Synonyms:exact_synonym: rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (RS)-isoconazole;   1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole;   Formula=C18H14Cl4N2O;   isoconazol;   isoconazolum;   rac-isoconazole;   racemic isoconazole
 xref: CAS:27523-40-6;   KEGG:D04624
 xref_mesh: MESH:C020382
 xref: PMID:21391489;   PMID:22285524;   PMID:23135097;   PMID:23563768;   PMID:23574019;   PMID:23574020;   PMID:23574021;   PMID:23574022;   PMID:23574023;   PMID:23574025;   PMID:23574026;   PMID:3043949;   PMID:3537934;   PMID:3606700;   PMID:3910548;   PMID:460303;   PMID:470977;   PMID:582987;   Reaxys:6442235;   Wikipedia:Isoconazole



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isoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO isoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      chemical substance 13190
        mixture 12396
          racemate 10478
            isoconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  heteroarene 16542
                                    monocyclic heteroarene 13505
                                      azole 12710
                                        diazole 8598
                                          imidazoles 7695
                                            1-\{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl\}imidazole 1
                                              (R)-isoconazole 1
                                                isoconazole 1
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