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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isoconazole
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Accession:CHEBI:82865 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-isoconazole. A broad-spectrum antibacterial drug used (as its nitrate salt) for treatment of dermatomycoses.
Synonyms:exact_synonym: rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (RS)-isoconazole;   1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole;   Formula=C18H14Cl4N2O;   isoconazol;   isoconazolum;   rac-isoconazole;   racemic isoconazole
 xref: CAS:27523-40-6;   KEGG:D04624
 xref_mesh: MESH:C020382
 xref: PMID:21391489;   PMID:22285524;   PMID:23135097;   PMID:23563768;   PMID:23574019;   PMID:23574020;   PMID:23574021;   PMID:23574022;   PMID:23574023;   PMID:23574025;   PMID:23574026;   PMID:3043949;   PMID:3537934;   PMID:3606700;   PMID:3910548;   PMID:460303;   PMID:470977;   PMID:582987;   Reaxys:6442235;   Wikipedia:Isoconazole


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isoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO isoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      chemical substance 14383
        mixture 13700
          racemate 12074
            isoconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  heteroarene 17114
                                    monocyclic heteroarene 14850
                                      azole 14355
                                        diazole 10467
                                          imidazoles 9870
                                            1-\{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl\}imidazole 1
                                              (R)-isoconazole 1
                                                isoconazole 1
paths to the root