Gene: Gss (glutathione synthetase) Rattus norvegicus
Analyze
Symbol:
Gss
Name:
glutathione synthetase
Description:
Exhibits anion binding activity; glutathione synthase activity; and identical protein binding activity. Involved in several processes, including glutathione biosynthetic process; response to amino acid; and response to tumor necrosis factor. Localizes to cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GSS (glutathione synthetase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
glutathione synthase; Glutathione synthetase gene; GSH synthetase; GSH-S
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GSS (glutathione synthetase) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Gss (glutathione synthetase) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Gss (glutathione synthetase)
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Homo sapiens (human):
GSS (glutathione synthetase)
Alliance
DIOPT (PANTHER|HGNC|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Danio rerio (zebrafish):
gss (glutathione synthetase)
Alliance
DIOPT (OMA|TreeFam|PhylomeDB|Ensembl Compara)
Saccharomyces cerevisiae (baker's yeast):
GSH2
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Drosophila melanogaster (fruit fly):
Gss1
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Caenorhabditis elegans (roundworm):
gss-1
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 3 151,076,254 - 151,106,557 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 151,076,254 - 151,106,557 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 157,443,738 - 157,474,042 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 146,057,517 - 146,087,820 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 3 145,963,138 - 145,993,442 (-) NCBI Celera 3 142,772,407 - 142,802,700 (-) NCBI Celera Cytogenetic Map 3 q42 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:11167850 more ... glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:10369661 more ... glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:14635114 , PMID:15717202 glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:12638941 more ... glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:15717202 more ... glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:15717202 , PMID:28492532 glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: Glutathione synthetase deficiency ClinVar glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by OMIM:266130 ClinVar PMID:8896573 glutathione synthetase deficiency ISO RGD:735330 8554872 ClinVar Annotator: match by term: 5-Oxoprolinuria ClinVar PMID:28492532 Hemolytic Anemia due to Glutathione Synthetase Deficiency of Erythrocytes ISO RGD:735330 8554872 ClinVar Annotator: match by term: Glutathione synthetase deficiency of erythrocytes, hemolytic anemia due to ClinVar PMID:11167850 more ... long QT syndrome ISO RGD:735330 8554872 ClinVar Annotator: match by term: Long QT syndrome ClinVar PMID:28492532
Imported Annotations - CTD
Animal Mammary Neoplasms ISO RGD:735330 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12376462 carcinoma ISO RGD:735330 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12376462 contact dermatitis ISO RGD:735330 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25724174 Mammary Neoplasms, Experimental ISO RGD:735330 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12376462 mouth disease ISO RGD:735330 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17682004 Imported Annotations - OMIM
glutathione synthetase deficiency ISO RGD:735330 7240710 OMIM Hemolytic Anemia due to Glutathione Synthetase Deficiency of Erythrocytes ISO RGD:735330 7240710 OMIM
(-)-epigallocatechin 3-gallate decreases expression ISO RGD:735330 6480464 epigallocatechin gallate results in decreased expression of GSS mRNA CTD PMID:18851785 (-)-epigallocatechin 3-gallate increases expression ISO RGD:10694 6480464 epigallocatechin gallate results in increased expression of GSS mRNA CTD PMID:25585349 (-)-quinic acid multiple interactions ISO RGD:735330 6480464 [Hydrogen Peroxide co-treated with Quinic Acid analog] results in increased expression of GSS mRNA CTD PMID:21751221 1,4-benzoquinone increases expression ISO RGD:735330 6480464 quinone results in increased expression of GSS protein CTD PMID:21059386 1,4-benzoquinone multiple interactions ISO RGD:735330 6480464 NFE2L2 mRNA affects the reaction [quinone results in increased expression of GSS protein] CTD PMID:21059386 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of GSS mRNA CTD PMID:20551477 17alpha-ethynylestradiol increases expression ISO RGD:10694 6480464 Ethinyl Estradiol results in increased expression of GSS mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:10694 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSS mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of GSS mRNA CTD PMID:17108234 , PMID:29097150 17beta-estradiol decreases expression ISO RGD:735330 6480464 Estradiol results in decreased expression of GSS mRNA CTD PMID:16705744 17beta-estradiol multiple interactions ISO RGD:10694 6480464 [Polyphenols co-treated with Estradiol] results in decreased expression of GSS mRNA CTD PMID:30077407 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:735330 6480464 Metribolone results in increased expression of GSS protein CTD PMID:17152098 1H-pyrazole increases expression ISO RGD:10694 6480464 pyrazole results in increased expression of GSS mRNA CTD PMID:17945193 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10694 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSS mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10694 6480464 Tetrachlorodibenzodioxin affects the expression of GSS mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GSS mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10694 6480464 Tetrachlorodibenzodioxin results in increased expression of GSS mRNA CTD PMID:15328365 , PMID:18163543 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 2-acetamidofluorene increases expression ISO RGD:10694 6480464 2-Acetylaminofluorene results in increased expression of GSS mRNA CTD PMID:17317680 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of GSS mRNA CTD PMID:15890375 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of GSS mRNA CTD PMID:10978506 2-tert-butylhydroquinone increases expression ISO RGD:10694 6480464 2-tert-butylhydroquinone results in increased expression of GSS mRNA CTD PMID:19183254 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3,7-dihydropurine-6-thione increases expression ISO RGD:735330 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin analog results in increased expression of GSS protein, alpha-Chlorohydrin results in increased expression of GSS protein CTD PMID:26072098 , PMID:26597043 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of GSS protein CTD PMID:26072098 3-methylcholanthrene increases activity ISO RGD:10694 6480464 Methylcholanthrene results in increased activity of GSS protein CTD PMID:23712962 3-methylcholanthrene increases expression ISO RGD:10694 6480464 Methylcholanthrene results in increased expression of GSS mRNA CTD PMID:23712962 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of GSS mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression ISO RGD:10694 6480464 4, 4'-diaminodiphenylmethane results in increased expression of GSS mRNA CTD PMID:18648102 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSS mRNA CTD PMID:15890375 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 4-hydroxynon-2-enal increases expression ISO RGD:10694 6480464 4-hydroxy-2-nonenal results in increased expression of GSS mRNA CTD PMID:19191707 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:12376462 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of GSS mRNA CTD PMID:22459607 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of GSS mRNA CTD PMID:15890375 aflatoxin B1 increases expression ISO RGD:10694 6480464 Aflatoxin B1 results in increased expression of GSS mRNA CTD PMID:19770486 alpha-D-galactose decreases expression ISO RGD:735330 6480464 Galactose results in decreased expression of GSS mRNA CTD PMID:23274001 alpha-D-galactose multiple interactions ISO RGD:735330 6480464 sodium bisulfide inhibits the reaction [Galactose results in decreased expression of GSS mRNA] CTD PMID:23274001 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GSS mRNA CTD PMID:16483693 Anetholtrithion increases activity ISO RGD:735330 6480464 Anethole Trithione results in increased activity of GSS protein CTD PMID:11213483 arecoline decreases expression ISO RGD:735330 6480464 Arecoline results in decreased expression of GSS mRNA CTD PMID:17682004 arsane increases expression ISO RGD:735330 6480464 Arsenic results in increased expression of GSS protein CTD PMID:18487201 arsane multiple interactions ISO RGD:735330 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 arsenic atom increases expression ISO RGD:735330 6480464 Arsenic results in increased expression of GSS protein CTD PMID:18487201 arsenic atom multiple interactions ISO RGD:735330 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 azathioprine increases expression ISO RGD:735330 6480464 Azathioprine results in increased expression of GSS mRNA CTD PMID:18222062 benzo[a]pyrene increases expression ISO RGD:10694 6480464 Benzo(a)pyrene results in increased expression of GSS mRNA CTD PMID:19770486 , PMID:21715664 benzo[a]pyrene multiple interactions ISO RGD:10694 6480464 [lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSS mRNA CTD PMID:28987381 bis(2-chloroethyl) sulfide increases expression ISO RGD:10694 6480464 Mustard Gas results in increased expression of GSS mRNA CTD PMID:18955075 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GSS mRNA CTD PMID:25181051 , PMID:30816183 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GSS gene CTD PMID:28505145 butan-1-ol multiple interactions ISO RGD:735330 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GSS mRNA CTD PMID:29432896 cadmium dichloride increases expression ISO RGD:735330 6480464 Cadmium Chloride results in increased expression of GSS protein CTD PMID:24527689 cadmium dichloride increases expression ISO RGD:10694 6480464 Cadmium Chloride results in increased expression of GSS mRNA CTD PMID:25528414 cadmium sulfide increases expression ISO RGD:735330 6480464 cadmium sulfide results in increased expression of GSS mRNA CTD PMID:27866839 celecoxib affects expression ISO RGD:10694 6480464 Celecoxib affects the expression of GSS mRNA CTD PMID:20562220 chloroprene increases expression ISO RGD:10694 6480464 Chloroprene results in increased expression of GSS mRNA CTD PMID:23125180 chlorpyrifos affects expression EXP 6480464 Chlorpyrifos affects the expression of GSS mRNA CTD PMID:19440498 cisplatin increases expression ISO RGD:735330 6480464 Cisplatin results in increased expression of GSS mRNA CTD PMID:27392435 , PMID:27594783 cisplatin multiple interactions ISO RGD:735330 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of GSS mRNA CTD PMID:27392435 clofibrate multiple interactions ISO RGD:10694 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA] CTD PMID:17585979 cobalt dichloride decreases expression ISO RGD:735330 6480464 cobaltous chloride results in decreased expression of GSS mRNA CTD PMID:19376846 copper atom decreases expression EXP 6480464 Copper results in decreased expression of GSS mRNA CTD PMID:22465980 copper atom affects binding ISO RGD:735330 6480464 GSS protein binds to Copper CTD PMID:15359738 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of GSS mRNA CTD PMID:22465980 copper(0) affects binding ISO RGD:735330 6480464 GSS protein binds to Copper CTD PMID:15359738 copper(II) sulfate decreases expression ISO RGD:735330 6480464 Copper Sulfate results in decreased expression of GSS mRNA CTD PMID:19549813 curcumin increases expression ISO RGD:10694 6480464 Curcumin results in increased expression of GSS mRNA CTD PMID:19183254 dextran sulfate multiple interactions ISO RGD:10694 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA CTD PMID:29950665 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of GSS mRNA CTD PMID:21266533 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA CTD PMID:18636392 dichlorine increases expression EXP 6480464 Chlorine results in increased expression of GSS mRNA CTD PMID:18636392 diethyl malate multiple interactions ISO RGD:10694 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA] CTD PMID:24814887 diethyl malate affects expression ISO RGD:10694 6480464 diethyl malate affects the expression of GSS mRNA CTD PMID:24814887 diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of GSS mRNA CTD PMID:15890375 enilconazole decreases expression ISO RGD:10694 6480464 enilconazole results in decreased expression of GSS mRNA CTD PMID:29451352 erdosteine increases expression ISO RGD:10694 6480464 erdosteine results in increased expression of GSS protein CTD PMID:26193055 ethanol multiple interactions ISO RGD:10694 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GSS mRNA CTD PMID:30517762 ethyl methanesulfonate increases expression ISO RGD:735330 6480464 Ethyl Methanesulfonate results in increased expression of GSS mRNA CTD PMID:23649840 fenamidone increases expression ISO RGD:10694 6480464 fenamidone results in increased expression of GSS mRNA CTD PMID:27029645 flutamide increases expression EXP 6480464 Flutamide results in increased expression of GSS mRNA CTD PMID:24136188 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of GSS mRNA CTD PMID:24793618 formaldehyde increases expression ISO RGD:735330 6480464 Formaldehyde results in increased expression of GSS mRNA CTD PMID:23649840 furan increases expression EXP 6480464 furan results in increased expression of GSS mRNA CTD PMID:25539665 , PMID:27402187 galactose multiple interactions ISO RGD:735330 6480464 sodium bisulfide inhibits the reaction [Galactose results in decreased expression of GSS mRNA] CTD PMID:23274001 galactose decreases expression ISO RGD:735330 6480464 Galactose results in decreased expression of GSS mRNA CTD PMID:23274001 genistein decreases expression ISO RGD:735330 6480464 Genistein results in decreased expression of GSS mRNA CTD PMID:16705744 glafenine increases expression EXP 6480464 Glafenine results in increased expression of GSS mRNA CTD PMID:24136188 glutathione multiple interactions ISO RGD:735330 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 Hexachloro-1,3-butadiene decreases activity EXP 6480464 hexachlorobutadiene results in decreased activity of GSS protein CTD PMID:15669050 hydrogen peroxide increases expression ISO RGD:735330 6480464 Hydrogen Peroxide results in increased expression of GSS mRNA CTD PMID:19902159 hydrogen peroxide multiple interactions ISO RGD:735330 6480464 [Hydrogen Peroxide co-treated with Quinic Acid analog] results in increased expression of GSS mRNA CTD PMID:21751221 hydroquinone increases expression ISO RGD:735330 6480464 hydroquinone results in increased expression of GSS protein CTD PMID:21059386 hydroquinone multiple interactions ISO RGD:735330 6480464 NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein] CTD PMID:21059386 hypochlorous acid increases expression ISO RGD:10694 6480464 Hypochlorous Acid results in increased expression of GSS mRNA CTD PMID:17980396 iron atom multiple interactions ISO RGD:735330 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GSS mRNA] CTD PMID:19073151 iron atom decreases expression ISO RGD:735330 6480464 Iron results in decreased expression of GSS mRNA CTD PMID:19073151 iron(0) decreases expression ISO RGD:735330 6480464 Iron results in decreased expression of GSS mRNA CTD PMID:19073151 iron(0) multiple interactions ISO RGD:735330 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GSS mRNA] CTD PMID:19073151 lead diacetate increases expression ISO RGD:10694 6480464 lead acetate results in increased expression of GSS mRNA CTD PMID:25270620 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of GSS mRNA CTD PMID:24136188 lithocholic acid affects expression ISO RGD:735330 6480464 Lithocholic Acid affects the expression of GSS mRNA, Lithocholic Acid affects the expression of GSS protein CTD PMID:20146260 lithocholic acid multiple interactions ISO RGD:735330 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA] more ... CTD PMID:20146260 LY294002 multiple interactions ISO RGD:735330 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GSS mRNA] CTD PMID:19073151 LY294002 decreases expression ISO RGD:735330 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of GSS mRNA CTD PMID:19073151 mercaptopurine increases expression ISO RGD:735330 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 mercury atom affects abundance ISO RGD:735330 6480464 GSS gene polymorphism affects the abundance of Mercury CTD PMID:21967774 mercury(0) affects abundance ISO RGD:735330 6480464 GSS gene polymorphism affects the abundance of Mercury CTD PMID:21967774 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of GSS mRNA CTD PMID:15890375 methyl methanesulfonate increases expression ISO RGD:735330 6480464 Methyl Methanesulfonate results in increased expression of GSS mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO RGD:10694 6480464 methylmercuric chloride results in increased expression of GSS mRNA CTD PMID:20061341 methylmercury chloride increases expression ISO RGD:735330 6480464 methylmercuric chloride results in increased expression of GSS protein CTD PMID:27180086 microcystin-LR increases expression ISO RGD:10694 6480464 cyanoginosin LR results in increased expression of GSS mRNA CTD PMID:17654400 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:10694 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSS mRNA CTD PMID:20061341 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:735330 6480464 Methylnitronitrosoguanidine results in decreased expression of GSS mRNA CTD PMID:12634122 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of GSS mRNA CTD PMID:19638242 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of GSS mRNA CTD PMID:15890375 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of GSS protein CTD PMID:19716841 naphthalene decreases expression ISO RGD:10694 6480464 naphthalene results in decreased expression of GSS mRNA CTD PMID:31020322 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of GSS mRNA CTD PMID:24136188 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of GSS mRNA CTD PMID:24136188 nitrogen dioxide decreases expression EXP 6480464 Nitrogen Dioxide results in decreased expression of GSS mRNA CTD PMID:16049373 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of GSS mRNA CTD PMID:12700408 more ... oligopeptide increases activity ISO RGD:10694 6480464 Oligopeptides results in increased activity of GSS protein CTD PMID:23796539 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA CTD PMID:18636392 paracetamol multiple interactions ISO RGD:10694 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA] CTD PMID:17585979 paracetamol increases expression ISO RGD:10694 6480464 Acetaminophen results in increased expression of GSS mRNA CTD PMID:25499718 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of GSS protein CTD PMID:16687475 paracetamol affects expression ISO RGD:10694 6480464 Acetaminophen affects the expression of GSS mRNA CTD PMID:17562736 paraoxon increases expression ISO RGD:735330 6480464 Paraoxon results in increased expression of GSS CTD PMID:24486155 pentachlorophenol increases expression ISO RGD:10694 6480464 Pentachlorophenol results in increased expression of GSS mRNA CTD PMID:23892564 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of GSS mRNA CTD PMID:19162173 phenobarbital affects expression ISO RGD:10694 6480464 Phenobarbital affects the expression of GSS mRNA CTD PMID:23091169 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of GSS mRNA CTD PMID:12376462 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of GSS mRNA CTD PMID:15890375 , PMID:22484513 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of GSS mRNA CTD PMID:15890375 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of GSS mRNA CTD PMID:16940010 purine-6-thiol increases expression ISO RGD:735330 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 quercetin increases expression ISO RGD:10694 6480464 Quercetin results in increased expression of GSS mRNA CTD PMID:19183254 rotenone increases expression ISO RGD:10694 6480464 Rotenone results in increased expression of GSS mRNA CTD PMID:23186747 S-adenosyl-L-methioninate multiple interactions ISO RGD:735330 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA], S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]] CTD PMID:20146260 S-adenosyl-L-methionine multiple interactions ISO RGD:735330 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA], S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]] CTD PMID:20146260 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases activity EXP 6480464 Buthionine Sulfoximine results in decreased activity of GSS protein CTD PMID:10904027 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP 6480464 Buthionine Sulfoximine results in increased expression of GSS mRNA CTD PMID:10978506 sodium arsenite decreases expression ISO RGD:735330 6480464 sodium arsenite results in decreased expression of GSS mRNA CTD PMID:12634122 sodium fluoride decreases expression ISO RGD:10694 6480464 Sodium Fluoride results in decreased expression of GSS protein CTD PMID:28918527 sunitinib increases expression ISO RGD:10694 6480464 sunitinib results in increased expression of GSS mRNA CTD PMID:30031043 T-2 Toxin affects expression EXP 6480464 T-2 Toxin affects the expression of GSS protein CTD PMID:26141394 tetrachloromethane increases expression ISO RGD:10694 6480464 Carbon Tetrachloride results in increased expression of GSS mRNA CTD PMID:27339419 , PMID:31870920 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of GSS mRNA CTD PMID:31150632 tetrachloromethane multiple interactions ISO RGD:10694 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GSS mRNA CTD PMID:30517762 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of GSS mRNA CTD PMID:10978506 titanium dioxide multiple interactions ISO RGD:10694 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA CTD PMID:29950665 toluene affects expression EXP 6480464 Toluene affects the expression of GSS mRNA CTD PMID:18653662 triclosan affects expression ISO RGD:735330 6480464 Triclosan affects the expression of GSS mRNA CTD PMID:31714634 tris(2-butoxyethyl) phosphate increases expression ISO RGD:10694 6480464 tris(2-butoxyethyl) phosphate results in increased expression of GSS mRNA CTD PMID:25808963 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of GSS mRNA CTD PMID:24136188 ursodeoxycholic acid multiple interactions ISO RGD:735330 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GSS mRNA] more ... CTD PMID:19073151 , PMID:20146260 ursodeoxycholic acid increases expression ISO RGD:735330 6480464 Ursodeoxycholic Acid results in increased expression of GSS mRNA CTD PMID:19073151 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of GSS mRNA CTD PMID:24136188 valproic acid affects expression ISO RGD:735330 6480464 Valproic Acid affects the expression of GSS mRNA CTD PMID:25979313 valproic acid decreases expression ISO RGD:735330 6480464 Valproic Acid results in decreased expression of GSS mRNA CTD PMID:28001369 zinc oxide multiple interactions ISO RGD:10694 6480464 Zinc Oxide affects the splicing of and results in increased expression of GSS mRNA CTD PMID:30500950
Gene-Chemical Interaction Annotations
