GSS (glutathione synthetase) - Rat Genome Database

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Gene: GSS (glutathione synthetase) Sus scrofa
Analyze
Symbol: GSS
Name: glutathione synthetase
RGD ID: 14049682
Description: ENCODES a protein that exhibits ATP binding (ortholog); glutathione binding (ortholog); glutathione synthase activity (ortholog); INVOLVED IN aging (ortholog); glutathione biosynthetic process (ortholog); response to amino acid (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); Alzheimer's disease (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH ethanol; folic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,312,720 - 38,342,304 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,316,199 - 38,342,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,511,098 - 43,539,281 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ethanol  (EXP)
folic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
GSS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,312,720 - 38,342,304 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,316,199 - 38,342,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,511,098 - 43,539,281 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2034,928,432 - 34,956,027 (-)EnsemblGRCh38hg38GRCh38
GRCh382034,928,432 - 34,956,027 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372033,516,235 - 33,543,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,979,897 - 33,007,262 (-)NCBINCBI36hg18NCBI36
Build 342032,979,897 - 33,007,262NCBI
Celera2030,265,329 - 30,292,695 (-)NCBI
Cytogenetic Map20q11.22NCBI
HuRef2030,294,556 - 30,321,979 (-)NCBIHuRef
CHM1_12033,417,456 - 33,444,826 (-)NCBICHM1_1
Gss
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,405,101 - 155,434,730 (-)NCBIGRCm39mm39
GRCm39 Ensembl2155,405,101 - 155,434,730 (-)Ensembl
GRCm382155,563,181 - 155,592,810 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,563,181 - 155,592,810 (-)EnsemblGRCm38mm10GRCm38
MGSCv372155,388,919 - 155,418,442 (-)NCBIGRCm37mm9NCBIm37
MGSCv362155,254,624 - 155,284,147 (-)NCBImm8
Celera2161,495,432 - 161,524,969 (-)NCBICelera
Cytogenetic Map2H1NCBI
Gss
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23144,047,849 - 144,078,197 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3144,047,850 - 144,078,198 (-)Ensembl
Rnor_6.03151,076,254 - 151,106,557 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,076,254 - 151,106,557 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,443,738 - 157,474,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43146,057,517 - 146,087,820 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13145,963,138 - 145,993,442 (-)NCBI
Celera3142,772,407 - 142,802,700 (-)NCBICelera
Cytogenetic Map3q42NCBI
Gss
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,427,581 - 26,463,781 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,427,581 - 26,483,380 (+)NCBIChiLan1.0ChiLan1.0
GSS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12032,381,745 - 32,409,327 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,381,745 - 32,409,297 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02031,256,734 - 31,284,356 (-)NCBIMhudiblu_PPA_v0panPan3
GSS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12423,973,807 - 24,000,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2423,901,045 - 23,997,286 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,619,971 - 23,646,466 (-)NCBI
ROS_Cfam_1.02424,665,657 - 24,692,375 (-)NCBI
UMICH_Zoey_3.12423,952,937 - 23,979,420 (-)NCBI
UNSW_CanFamBas_1.02424,048,251 - 24,074,736 (-)NCBI
UU_Cfam_GSD_1.02424,487,171 - 24,513,688 (-)NCBI
Gss
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640172,955,595 - 172,983,992 (-)NCBI
SpeTri2.0NW_0049365615,765,637 - 5,793,951 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1239,230,629 - 39,258,511 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl239,230,487 - 39,254,648 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605087,554,278 - 87,582,240 (+)NCBIVero_WHO_p1.0
Gss
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248424,445,015 - 4,470,124 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 3 2 5 2 1
Low 7 4 3 2 18 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007972   ⟹   ENSSSCP00000007759
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1738,317,533 - 38,342,304 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000053407   ⟹   ENSSSCP00000034338
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1738,312,720 - 38,342,262 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000067800   ⟹   ENSSSCP00000067789
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1738,312,720 - 38,342,262 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000068272   ⟹   ENSSSCP00000065814
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1738,331,691 - 38,342,253 (-)Ensembl
RefSeq Acc Id: NM_001244625   ⟹   NP_001231554
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11738,316,199 - 38,342,253 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001231554 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001231554   ⟸   NM_001244625
- Sequence:
RefSeq Acc Id: ENSSSCP00000065814   ⟸   ENSSSCT00000068272
RefSeq Acc Id: ENSSSCP00000007759   ⟸   ENSSSCT00000007972
RefSeq Acc Id: ENSSSCP00000067789   ⟸   ENSSSCT00000067800
RefSeq Acc Id: ENSSSCP00000034338   ⟸   ENSSSCT00000053407
Protein Domains
GSH_synthase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007287 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000007759 UniProtKB/TrEMBL
  ENSSSCP00000034338 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000065814 UniProtKB/TrEMBL
  ENSSSCP00000067789 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007972 UniProtKB/TrEMBL
  ENSSSCT00000053407 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000067800 UniProtKB/TrEMBL
  ENSSSCT00000068272 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1080.10 UniProtKB/TrEMBL
  3.30.1490.50 UniProtKB/TrEMBL
  3.30.1490.80 UniProtKB/TrEMBL
  3.40.50.1760 UniProtKB/TrEMBL
InterPro Glutathione_synthase UniProtKB/TrEMBL
  Glutathione_synthase_a-hlx UniProtKB/TrEMBL
  Glutathione_synthase_C_euk UniProtKB/TrEMBL
  Glutathione_synthase_N_euk UniProtKB/TrEMBL
  GSH-S_sub-bd_sf UniProtKB/TrEMBL
  GSH_synth_subst-bd UniProtKB/TrEMBL
  PreATP-grasp_dom_sf UniProtKB/TrEMBL
NCBI Gene GSS ENTREZGENE
PANTHER PTHR11130 UniProtKB/TrEMBL
Pfam GSH_synth_ATP UniProtKB/TrEMBL
  GSH_synthase UniProtKB/TrEMBL
PIRSF GSHase UniProtKB/TrEMBL
Superfamily-SCOP SSF52440 UniProtKB/TrEMBL
TIGRFAMs glut_syn_euk UniProtKB/TrEMBL
UniProt A0A286ZRS0_PIG UniProtKB/TrEMBL
  A0A5G2QUF4_PIG UniProtKB/TrEMBL
  A0A5G2R5F9_PIG UniProtKB/TrEMBL
  F1S4X9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:96338 ENTREZGENE