Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Tut7 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TUT7 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TUT7 mRNA and ethylene dichloride results in decreased expression of ZCCHC6 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Tut7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TUT7 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZCCHC6 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of ZCCHC6 mRNA | CTD | PMID:32145629 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of ZCCHC6 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TUT7 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TUT7 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tut7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TUT7 mRNA | CTD | PMID:21570461 and PMID:24680724 | 2-hydroxypropanoic acid | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ZCCHC6 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Tut7 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of TUT7 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Tut7 (Mus musculus) | 6480464 | bisphenol S affects the methylation of ZCCHC6 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ZCCHC6 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases methylation | ISO | TUT7 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TUT7 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TUT7 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ZCCHC6 mRNA | CTD | PMID:33167477 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of ZCCHC6 mRNA | CTD | PMID:30047161 | antimycin A | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of TUT7 mRNA | CTD | PMID:33512557 | antirheumatic drug | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TUT7 mRNA | CTD | PMID:24449571 | atrazine | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of TUT7 mRNA | CTD | PMID:22378314 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of TUT7 gene | CTD | PMID:35440735 | benzo[a]pyrene | increases mutagenesis | ISO | TUT7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TUT7 gene | CTD | PMID:25435355 | benzo[a]pyrene | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TUT7 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | Tut7 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of ZCCHC6 exon and Benzo(a)pyrene results in increased methylation of ZCCHC6 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | TUT7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ZCCHC6 promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TUT7 mRNA and bisphenol A affects the expression of ZCCHC6 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TUT7 mRNA | CTD | PMID:33221593 | chlorpyrifos | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of TUT7 mRNA | CTD | PMID:37019170 | clorgyline | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of TUT7 mRNA | CTD | PMID:19691856 | copper atom | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Copper results in increased expression of TUT7 mRNA | CTD | PMID:16629173 | copper(0) | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Copper results in increased expression of TUT7 mRNA | CTD | PMID:16629173 | copper(II) sulfate | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TUT7 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TUT7 mRNA | CTD | PMID:25562108 | diethylstilbestrol | affects expression | ISO | TUT7 (Homo sapiens) | 6480464 | Diethylstilbestrol affects the expression of TUT7 mRNA | CTD | PMID:36621641 | dioxygen | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of TUT7 mRNA | CTD | PMID:22629407 | dioxygen | multiple interactions | ISO | Tut7 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of TUT7 mRNA] | CTD | PMID:22629407 | elemental selenium | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Selenium results in decreased expression of TUT7 mRNA | CTD | PMID:19244175 | fenthion | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | Fenthion results in decreased expression of TUT7 mRNA | CTD | PMID:34813904 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of TUT7 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Tut7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TUT7 mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | TUT7 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TUT7 protein | CTD | PMID:37730182 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of TUT7 mRNA | CTD | PMID:24136188 | ketoconazole | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Ketoconazole results in increased expression of TUT7 mRNA | CTD | PMID:36621641 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of ZCCHC6 mRNA | CTD | PMID:30467583 | methidathion | affects expression | ISO | Tut7 (Mus musculus) | 6480464 | methidathion affects the expression of TUT7 mRNA | CTD | PMID:34813904 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of ZCCHC6 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TUT7 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TUT7 mRNA | CTD | PMID:28001369 | methylparaben | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | methylparaben results in increased expression of TUT7 mRNA | CTD | PMID:31745603 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of TUT7 mRNA | CTD | PMID:24136188 | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of TUT7 mRNA | CTD | PMID:24136188 | paracetamol | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TUT7 mRNA | CTD | PMID:21420995 and PMID:26690555 | pentachlorophenol | increases expression | ISO | Tut7 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TUT7 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of TUT7 mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tut7 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TUT7 mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | Tut7 (Mus musculus) | 6480464 | Phenobarbital affects the expression of TUT7 mRNA | CTD | PMID:23091169 | picoxystrobin | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of TUT7 mRNA | CTD | PMID:33512557 | progesterone | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Progesterone results in increased expression of TUT7 mRNA | CTD | PMID:20864642 | propiconazole | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TUT7 mRNA | CTD | PMID:21278054 | rac-lactic acid | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ZCCHC6 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | TUT7 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TUT7 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TUT7 mRNA | CTD | PMID:33512557 | selenium atom | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Selenium results in decreased expression of TUT7 mRNA | CTD | PMID:19244175 | silver atom | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Silver results in increased expression of TUT7 mRNA | CTD | PMID:26014281 | silver(0) | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Silver results in increased expression of TUT7 mRNA | CTD | PMID:26014281 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of ZCCHC6 mRNA | CTD | PMID:30047161 | tebufenpyrad | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of TUT7 mRNA | CTD | PMID:33512557 | temozolomide | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of TUT7 mRNA | CTD | PMID:31758290 | testosterone | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of ZCCHC6 mRNA | CTD | PMID:33359661 | thifluzamide | decreases expression | ISO | TUT7 (Homo sapiens) | 6480464 | thifluzamide results in decreased expression of TUT7 mRNA | CTD | PMID:33512557 | torcetrapib | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of TUT7 mRNA | CTD | PMID:23228038 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of TUT7 mRNA | CTD | PMID:33387578 | tungsten | decreases expression | ISO | Tut7 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ZCCHC6 mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | TUT7 (Homo sapiens) | 6480464 | Urethane results in increased expression of TUT7 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | TUT7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TUT7 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Tut7 (Mus musculus) | 6480464 | Valproic Acid affects the expression of TUT7 mRNA | CTD | PMID:17963808 | zinc atom | multiple interactions | ISO | TUT7 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of TUT7 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | TUT7 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of TUT7 mRNA | CTD | PMID:18593933 | |