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Gene: Pmvk (phosphomevalonate kinase) Rattus norvegicus
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Symbol: Pmvk
Name: phosphomevalonate kinase
Description: Exhibits phosphomevalonate kinase activity. Involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to localize to the cytosol and peroxisome. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human PMVK (phosphomevalonate kinase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310645; MGC105660
Orthologs:
Homo sapiens (human) : PMVK (phosphomevalonate kinase)  HGNC  Alliance
Mus musculus (house mouse) : Pmvk (phosphomevalonate kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pmvk (phosphomevalonate kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : PMVK (phosphomevalonate kinase)
Canis lupus familiaris (dog) : PMVK (phosphomevalonate kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pmvk (phosphomevalonate kinase)
Sus scrofa (pig) : PMVK (phosphomevalonate kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,784,329 - 188,793,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02208,198,238 - 208,207,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,655,658 - 181,665,214 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12181,605,763 - 181,615,319 (+)NCBI
Celera2168,817,684 - 168,827,240 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pmvk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310812
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.