Pmvk (phosphomevalonate kinase) - Rat Genome Database

Name: Pmvk
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Pmvk (phosphomevalonate kinase) Ictidomys tridecemlineatus

Analyze

Symbol:

Pmvk

Name:

phosphomevalonate kinase

RGD ID:

12468155

Description:

ENCODES a protein that exhibits phosphomevalonate kinase activity (ortholog); INVOLVED IN isopentenyl diphosphate biosynthetic process, mevalonate pathway (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN peroxisome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

phosphomevalonate kinase, transcript variant X1; phosphomevalonate kinase, transcript variant X2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PMVK (phosphomevalonate kinase)	NCBI	Ortholog
Mus musculus (house mouse):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,234 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	4,473,359 - 4,482,631 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	4,473,554 - 4,482,396 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

porokeratosis (ISO)

Porokeratosis 1, Multiple Types (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol biosynthetic process (IEA)

cholesterol metabolic process (IEA)

isopentenyl diphosphate biosynthetic process, mevalonate pathway (IEA,ISO)

lipid metabolic process (IEA)

response to cholesterol (IEA)

steroid biosynthetic process (IEA)

steroid metabolic process (IEA)

sterol biosynthetic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

peroxisome (IEA,ISO)

Molecular Function

ATP binding (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

phosphomevalonate kinase activity (IEA,ISO)

protein binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Pmvk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,234 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	4,473,359 - 4,482,631 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	4,473,554 - 4,482,396 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PMVK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	154,924,740 - 154,942,658 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	154,924,740 - 154,936,719 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	154,897,216 - 154,915,134 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	153,163,832 - 153,176,108 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	151,710,280 - 151,722,540	NCBI
Celera	1	127,968,233 - 127,980,509 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	126,259,154 - 126,271,445 (-)	NCBI		HuRef
CHM1_1	1	156,293,587 - 156,305,863 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	154,064,101 - 154,082,019 (-)	NCBI		T2T-CHM13v2.0

Pmvk
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	89,361,848 - 89,376,321 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	89,361,848 - 89,376,320 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	89,454,541 - 89,469,014 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	89,454,541 - 89,469,013 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	89,263,040 - 89,272,931 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	89,545,243 - 89,554,933 (+)	NCBI		MGSCv36	mm8
Celera	3	89,494,449 - 89,504,138 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.13	NCBI

Pmvk
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	177,174,344 - 177,184,076 (+)	NCBI		GRCr8
mRatBN7.2	2	174,876,586 - 174,886,365 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,876,657 - 174,886,364 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,022,396 - 182,031,869 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	180,044,785 - 180,054,258 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	174,645,467 - 174,654,973 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	188,784,329 - 188,793,890 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	188,784,222 - 188,793,895 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	208,198,238 - 208,207,794 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	181,655,658 - 181,665,214 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	181,605,763 - 181,615,319 (+)	NCBI
Celera	2	168,817,684 - 168,827,240 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Pmvk
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,421,562 - 1,440,038 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,421,562 - 1,440,038 (-)	NCBI	ChiLan1.0	ChiLan1.0

PMVK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	94,903,218 - 94,915,762 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	94,635,585 - 94,647,862 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	130,273,246 - 130,286,614 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	133,882,837 - 133,894,818 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	133,882,840 - 133,894,818 (-)	Ensembl	panpan1.1		panPan2

PMVK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	42,532,968 - 42,563,618 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	42,533,217 - 42,540,625 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	42,024,242 - 42,060,899 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	42,403,302 - 42,439,920 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	42,403,373 - 42,414,566 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	42,182,992 - 42,219,593 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	42,236,594 - 42,273,239 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	42,520,185 - 42,556,794 (+)	NCBI		UU_Cfam_GSD_1.0

PMVK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	94,861,712 - 94,874,771 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	94,861,500 - 94,913,743 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	103,634,269 - 103,685,533 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PMVK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	8,893,297 - 8,906,882 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	8,894,786 - 8,906,873 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	8,229,305 - 8,242,091 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pmvk
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	2,543,862 - 2,553,237 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	2,544,136 - 2,552,591 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005331310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013361222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000003632 ⟹ ENSSTOP00000003252

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936580	4,473,359 - 4,482,631 (-)	Ensembl

RefSeq Acc Id:

XM_005331310 ⟹ XP_005331367

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,028 (-)	NCBI
SpeTri2.0	NW_004936580	4,473,554 - 4,482,396 (-)	NCBI

Sequence:

show sequence

GCGCGGAGTGGCCCGATTTCAGGGGTACGATGGGTCCGCGTTAGGGATAGGAAAGCCGAGTGGC
CTCATGGCCCCGCAGGGAGGCGCCCCCCGACTGGTGCTGCTGTTTAGCGGGAAGAGAAAATCCG
GGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGACTTGGAGCTGACATCTGTGCTATTCTCCG
GCTCTCTGGCCCACTCAAGGAGCAGTATGCTCAGGAGCACAGCCTGGACTTCCAGAGACTTCTG
GACGCCAGCACCTACAAGGAGGCTTATCGGAGCGACATGATCCGCTGGGGGGAGGAGAAGCGCC
GGGCCGACCCGGGCTTTTTCTGCAGGAAGATCGTAGAAGGCGTCTCCCAGCCCATCTGGCTGGT
GAGTGACACACGGAGGGTGTCTGACATCCAGTGGTTCCGGGAGGCCTACGGGGCTGCGATGCAG
ACGGTCCGCGTGTTCGCCTCGGAGCAGAGCCGGCAGCAGCGGGGCTGGGTGTTCACGCCAGGGG
TGGATGACGCTGAGTCGGAATGTGGCCTGGACGACTTTGGGGACTTTGACTGGGTCATCGAGAA
CCACGGAGATGAGCAGCACCTGGAGCAGCAGTTGGCCAACCTGCTGAAATTCGTCCACTCAAGA
CTTTAGCTGTCAGGCTCCCGAAGTGAGCTGGGCGTGCTGGGCTGGCACGGGGTTGGCTCTGCAG
GACGTGGGGGTCCCCACCCTGACCAAGGTGGGGGAGCAGGCAGGGCCTGTCCAGATTTCTTGGG
GTGAGGGCGGGTGGTTGTCAGGCGAGTTAGAGAACCTTGAGGGAGCTGGCTCTCTGTGGAGAAG
GCGCCCGACTTCCCTGCCTCCTCAGGAGGACACTTGGAGGGCGCAGGAGGGAGGATTCTGTGTG
CTTGAAGCAGGAACATGGCCATTGCCACGGGAGCCAGGCCTGGTGGCTCTGGTGGCCCCTCCCT
GTCTGGATGTTCTCAGCCCCTTGTTCTGGGCAAGGACCCAGAGCTCCCTGGTGTGCTTACTAAT
AAACCTCCTGGGAACACA

hide sequence

RefSeq Acc Id:

XM_013361222 ⟹ XP_013216676

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,443,172 - 25,446,902 (-)	NCBI
SpeTri2.0	NW_004936580	4,473,554 - 4,477,482 (-)	NCBI

Sequence:

show sequence

TGGAACAGGGCATCAGGTGGGGACCAAGGGGCTGAGAGCTGCTGCAGATGCAGTGGCACAAGTC
CCACTGGCTCCCGAGGCAGGAGGATCACAAGTTTGAGGTCAGCTGGGCACCTTCGCGAGTAAGT
GAAAAAGGCTGGGAATGTGGCTCCGTGGTGCGTGCCTCTGGCTCAGTCTCCATCCCTACCCTCA
TCCCAGAAAAGCAGGAGGAGAGAGGGAGCCTGGGGCGGAGGCCTTGCTGAAGGGGAACCTGACC
TTTCACACCCGTTCCTGGCCCGGACCCTCTGGCTGTGCCCCTCTGGCTGTCAGGATCCTGGAGA
AGGGGAGGCCAGGAGCACAGCCTGGACTTCCAGAGACTTCTGGACGCCAGCACCTACAAGGAGG
CTTATCGGAGCGACATGATCCGCTGGGGGGAGGAGAAGCGCCGGGCCGACCCGGGCTTTTTCTG
CAGGAAGATCGTAGAAGGCGTCTCCCAGCCCATCTGGCTGGTGAGTGACACACGGAGGGTGTCT
GACATCCAGTGGTTCCGGGAGGCCTACGGGGCTGCGATGCAGACGGTCCGCGTGTTCGCCTCGG
AGCAGAGCCGGCAGCAGCGGGGCTGGGTGTTCACGCCAGGGGTGGATGACGCTGAGTCGGAATG
TGGCCTGGACGACTTTGGGGACTTTGACTGGGTCATCGAGAACCACGGAGATGAGCAGCACCTG
GAGCAGCAGTTGGCCAACCTGCTGAAATTCGTCCACTCAAGACTTTAGCTGTCAGGCTCCCGAA
GTGAGCTGGGCGTGCTGGGCTGGCACGGGGTTGGCTCTGCAGGACGTGGGGGTCCCCACCCTGA
CCAAGGTGGGGGAGCAGGCAGGGCCTGTCCAGATTTCTTGGGGTGAGGGCGGGTGGTTGTCAGG
CGAGTTAGAGAACCTTGAGGGAGCTGGCTCTCTGTGGAGAAGGCGCCCGACTTCCCTGCCTCCT
CAGGAGGACACTTGGAGGGCGCAGGAGGGAGGATTCTGTGTGCTTGAAGCAGGAACATGGCCAT
TGCCACGGGAGCCAGGCCTGGTGGCTCTGGTGGCCCCTCCCTGTCTGGATGTTCTCAGCCCCTT
GTTCTGGGCAAGGACCCAGAGCTCCCTGGTGTGCTTACTAATAAACCTCCTGGGAACACA

hide sequence

RefSeq Acc Id:

XM_040287646 ⟹ XP_040143580

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,191 (-)	NCBI

RefSeq Acc Id:

XM_040287647 ⟹ XP_040143581

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,443,172 - 25,451,991 (-)	NCBI

RefSeq Acc Id:

XM_040287648 ⟹ XP_040143582

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,234 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005331367	(Get FASTA)	NCBI Sequence Viewer
	XP_013216676	(Get FASTA)	NCBI Sequence Viewer
	XP_040143580	(Get FASTA)	NCBI Sequence Viewer
	XP_040143581	(Get FASTA)	NCBI Sequence Viewer
	XP_040143582	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003252.2
GenBank Protein	KAG3281697	(Get FASTA)	NCBI Sequence Viewer
	KAG3281698	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005331367 ⟸ XM_005331310
- Peptide Label:	isoform X1
- UniProtKB:	I3M2M8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPQGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADICAILRLSGPLKEQYAQEHSLDFQRLLD ASTYKEAYRSDMIRWGEEKRRADPGFFCRKIVEGVSQPIWLVSDTRRVSDIQWFREAYGAAMQT VRVFASEQSRQQRGWVFTPGVDDAESECGLDDFGDFDWVIENHGDEQHLEQQLANLLKFVHSRL hide sequence

RefSeq Acc Id:	XP_013216676 ⟸ XM_013361222
- Peptide Label:	isoform X2
- Sequence:	show sequence MIRWGEEKRRADPGFFCRKIVEGVSQPIWLVSDTRRVSDIQWFREAYGAAMQTVRVFASEQSRQ QRGWVFTPGVDDAESECGLDDFGDFDWVIENHGDEQHLEQQLANLLKFVHSRL hide sequence

RefSeq Acc Id:	XP_040143582 ⟸ XM_040287648
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040143580 ⟸ XM_040287646
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040143581 ⟸ XM_040287647
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSSTOP00000003252 ⟸ ENSSTOT00000003632

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000003639	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000003632.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Pmev_kin_anim	UniProtKB/TrEMBL
NCBI Gene	Pmvk	ENTREZGENE
PANTHER	PHOSPHOMEVALONATE KINASE	UniProtKB/TrEMBL
	PTHR13101	UniProtKB/TrEMBL
Pfam	P-mevalo_kinase	UniProtKB/TrEMBL
PIRSF	PMK_anim	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	I3M2M8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB