PMVK (phosphomevalonate kinase) - Rat Genome Database

Name: PMVK
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: PMVK (phosphomevalonate kinase) Sus scrofa

Analyze

Symbol:

PMVK

Name:

phosphomevalonate kinase

RGD ID:

14180302

Description:

ENCODES a protein that exhibits phosphomevalonate kinase activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); isopentenyl diphosphate biosynthetic process, mevalonate pathway (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); peroxisome (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

PMKase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PMVK (phosphomevalonate kinase)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PMVK (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pmvk (phosphomevalonate kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	94,861,712 - 94,874,771 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	94,861,500 - 94,913,743 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	103,634,269 - 103,685,533 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

porokeratosis (ISO)

Porokeratosis 1, Multiple Types (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol biosynthetic process (IBA,IEA,ISS)

isopentenyl diphosphate biosynthetic process, mevalonate pathway (IBA,IEA,ISO)

response to cholesterol (IEA)

sterol biosynthetic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISS)

peroxisome (ISO,ISS)

Molecular Function

ATP binding (IEA)

kinase activity (IEA)

phosphomevalonate kinase activity (IBA,IEA,ISO,ISS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:7814412	PMID:8663599	PMID:14681463	PMID:15679890	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PMVK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	94,861,712 - 94,874,771 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	94,861,500 - 94,913,743 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	103,634,269 - 103,685,533 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PMVK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	154,924,740 - 154,942,658 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	154,924,740 - 154,936,719 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	154,897,216 - 154,915,134 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	153,163,832 - 153,176,108 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	151,710,280 - 151,722,540	NCBI
Celera	1	127,968,233 - 127,980,509 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	126,259,154 - 126,271,445 (-)	NCBI		HuRef
CHM1_1	1	156,293,587 - 156,305,863 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	154,064,101 - 154,082,019 (-)	NCBI		T2T-CHM13v2.0

Pmvk
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	89,361,848 - 89,376,321 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	89,361,848 - 89,376,320 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	89,454,541 - 89,469,014 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	89,454,541 - 89,469,013 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	89,263,040 - 89,272,931 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	89,545,243 - 89,554,933 (+)	NCBI		MGSCv36	mm8
Celera	3	89,494,449 - 89,504,138 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.13	NCBI

Pmvk
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	177,174,344 - 177,184,076 (+)	NCBI		GRCr8
mRatBN7.2	2	174,876,586 - 174,886,365 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,876,657 - 174,886,364 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,022,396 - 182,031,869 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	180,044,785 - 180,054,258 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	174,645,467 - 174,654,973 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	188,784,329 - 188,793,890 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	188,784,222 - 188,793,895 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	208,198,238 - 208,207,794 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	181,655,658 - 181,665,214 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	181,605,763 - 181,615,319 (+)	NCBI
Celera	2	168,817,684 - 168,827,240 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Pmvk
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,421,562 - 1,440,038 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,421,562 - 1,440,038 (-)	NCBI	ChiLan1.0	ChiLan1.0

PMVK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	94,903,218 - 94,915,762 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	94,635,585 - 94,647,862 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	130,273,246 - 130,286,614 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	133,882,837 - 133,894,818 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	133,882,840 - 133,894,818 (-)	Ensembl	panpan1.1		panPan2

PMVK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	42,532,968 - 42,563,618 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	42,533,217 - 42,540,625 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	42,024,242 - 42,060,899 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	42,403,302 - 42,439,920 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	42,403,373 - 42,414,566 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	42,182,992 - 42,219,593 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	42,236,594 - 42,273,239 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	42,520,185 - 42,556,794 (+)	NCBI		UU_Cfam_GSD_1.0

Pmvk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,443,172 - 25,452,234 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	4,473,359 - 4,482,631 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	4,473,554 - 4,482,396 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PMVK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	8,893,297 - 8,906,882 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	8,894,786 - 8,906,873 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	8,229,305 - 8,242,091 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pmvk
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	2,543,862 - 2,553,237 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	2,544,136 - 2,552,591 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PMVK
1551 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	2					1	2	1
Low	8	4	3	5	2	22		2	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001168416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013996999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021088511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB530141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK232124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY609880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU207227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01005098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L77214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000007157 ⟹ ENSSSCP00000006964

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	94,861,694 - 94,878,921 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000096702 ⟹ ENSSSCP00000076215

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	94,861,712 - 94,874,771 (+)	Ensembl

RefSeq Acc Id:

NM_001168416 ⟹ NP_001161888

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	94,861,668 - 94,873,211 (+)	NCBI

Sequence:

show sequence

CCATTCTGTGCCGGGTGGCTCGATTTAAGGGGTAAGGGTTCAGGATCCGCTGTAGGGATCGCAA
AGCGTAGCGGCCCCATGGCACCCCTGGGAAGCGTCCCGCGGTTGGTGCTGCTTTTCAGCGGGAA
GAGGAAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGGCTCGGAGCTGATGTCTGT
GCCATCCTCCGGCTCTCGGGCCCACTCAAGGAGCAGTATGCTCAGGAGCATGGCTTGGACTTCC
AGAGACTCCTGGACGCCAGCACCTACAAGGAGTCCTATCGGAAGGACATGATCCGCTGGGGCCA
GGAGAAGCGCCAGGCTGACCCAGGTTTCTTCTGCAGGAAGATCGTGGAGGGCGTCTCCCAGCCC
ATCTGGCTGGTGAGTGACACTCGGAGACTGTCTGACATCCAGTGGTTTCAGGAGACCTATGGGG
CTGTGACGCAGACGGTCCGAGTGGTGGCCACGGAGCAGAGCCGCCAGCAGCGGGGCTGGGTGTT
CATACCAGGGGTGGATGATGCTGAGTCAGAGTGTGGCCTGGACGACTTCGGGGCCTTCGATTGG
GTCATCGAGAACCACGGAGATGAGCAGCACCTGGAGGAGCAGTTGGGGCACCTGATAGAATTTG
TTCACTCCAGGCTTTAGCTGGCATGTTCTAGGAGTGTGTCGGGGGCTGCCGGGGTAAAGGGGCG
CTGACTGTGCTGGACATAGGGTCACTGATGCTGGCGGAGGTCGAGGAGCAGACAGAGGGCCTGG
GTCTGGTGTCTGGGTGCTGTCAGGCATCAGACAGGTTAGGAACTCACCGGGGACCTCATTTCTT
TATGGAAAGGACAGCCCTACCTCTTTAGAGGGAGACTTAAAGAGCGAGGGGGTTGGGGGTGAGT
TGGCTGTGCTTAAAACTGAAGCATCACCATCTCTATGGGTACCAGGCCTGTCAGCCAGCAGCGG
CCTTGCTTCCCTGACCGGATGCTCTCAGCCCCTTGTTCTGTGCAAGAGCCCAGGGCTCCCCAGT
GTATAAGCTAATAAACCTCCTTGGAGCACCTGCTCAGAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_013996999 ⟹ XP_013852453

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	94,861,500 - 94,913,743 (+)	NCBI

Sequence:

show sequence

GAGAAAGCTGCCCAGGGACTTAACCTTCTTTCTCTCCACAGTCCATTTATGTAGGCTTTAGTGT
AAAGGCACAGAAGCACTTGTGCAGGTTGACCATCCTCTCCACGGCCATGGAGAAGACGGGCGGG
CGGAACCCCTTCTTGTTGCCGCTCCATCCAGTGGCCGCGTCCATTCTGTGCCGGGTGGCTCGAT
TTAAGGGGTAAGGGTTCAGGATCCGCTGTAGGGATCGCAAAGCGTAGCGGCCCCATGGCACCCC
TGGGAAGCGTCCCGCGGTTGGTGCTGCTTTTCAGCGGGAAGAGGAAATCCGGGAAGGACTTCGT
GACCGAGGCGCTGCAGAGCAGGCTCGGAGCTGATGTCTGTGCCATCCTCCGGCTCTCGGGCCCA
CTCAAGGAGCAGTATGCTCAGGAGCATGGCTTGGACTTCCAGAGACTCCTGGACGCCAGCACCT
ACAAGGAGTCCTATCGGAAGGACATGATCCGCTGGGGCCAGGAGAAGCGCCAGGCTGACCCAGG
TTTCTTCTGCAGGAAGATCGTGGAGGGCGTCTCCCAGCCCATCTGGCTGGTGAGTGACACTCGG
AGACTGTCTGACATCCAGTGGTTTCAGGAGACCTATGGGGCTGTGACGCAGACGGTCCGAGTGG
TGGCCACGGAGCAGAGCCGCCAGCAGCGGGGCTGGGTGTTCATACCAGACTTTTTGTGATGAGC
AAGCTTTTCCGATGAACATTCAGAAACATAAATAAGTTAAAACACTGGACCCCTCCGATGGCTT
CACATTGGCATAGATCAGAAGAGTCCTTCGAGGGATGGAAGAAGAGCTTGGCGATCATCAGATT
CTCTCGTCCACATGTGTAAAAAAACATACAGTGATAT

hide sequence

RefSeq Acc Id:

XM_021088511 ⟹ XP_020944170

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	94,864,459 - 94,873,211 (+)	NCBI

Sequence:

show sequence

ATGTCTGTGCCATCCTCCGGCTCTCGGGCCCACTCAAGGAGCAGTATGCTCAGGAAGATCGTGG
AGGGCGTCTCCCAGCCCATCTGGCTGGTGAGTGACACTCGGAGACTGTCTGACATCCAGTGGTT
TCAGGAGACCTATGGGGCTGTGACGCAGACGGTCCGAGTGGTGGCCACGGAGCAGAGCCGCCAG
CAGCGGGGCTGGGTGTTCATACCAGGGGTGGATGATGCTGAGTCAGAGTGTGGCCTGGACGACT
TCGGGGCCTTCGATTGGGTCATCGAGAACCACGGAGATGAGCAGCACCTGGAGGAGCAGTTGGG
GCACCTGATAGAATTTGTTCACTCCAGGCTTTAGCTGGCATGTTCTAGGAGTGTGTCGGGGGCT
GCCGGGGTAAAGGGGCGCTGACTGTGCTGGACATAGGGTCACTGATGCTGGCGGAGGTCGAGGA
GCAGACAGAGGGCCTGGGTCTGGTGTCTGGGTGCTGTCAGGCATCAGACAGGTTAGGAACTCAC
CGGGGACCTCATTTCTTTATGGAAAGGACAGCCCTACCTCTTTAGAGGGAGACTTAAAGAGCGA
GGGGGTTGGGGGTGAGTTGGCTGTGCTTAAAACTGAAGCATCACCATCTCTATGGGTACCAGGC
CTGTCAGCCAGCAGCGGCCTTGCTTCCCTGACCGGATGCTCTCAGCCCCTTGTTCTGTGCAAGA
GCCCAGGGCTCCCCAGTGTATAAGCTAATAAACCTCCTTGGAGCACCTGCTCAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001161888	(Get FASTA)	NCBI Sequence Viewer
	XP_013852453	(Get FASTA)	NCBI Sequence Viewer
	XP_020944170	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC37331	(Get FASTA)	NCBI Sequence Viewer
	BAI48089	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000076215
	ENSSSCP00000076215.1
	ENSSSCP00025016998.1
	ENSSSCP00035048279.1
	ENSSSCP00040046582.1
	ENSSSCP00045017945.1
	ENSSSCP00050011423.1
	ENSSSCP00055017104.1
	ENSSSCP00070047606.1
GenBank Protein	Q29081	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013852453 ⟸ XM_013996999
- Peptide Label:	isoform X1
- Sequence:	show sequence MAPLGSVPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQRLLD ASTYKESYRKDMIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQETYGAVTQT VRVVATEQSRQQRGWVFIPDFL hide sequence

RefSeq Acc Id:	NP_001161888 ⟸ NM_001168416
- UniProtKB:	F1RGP9 (UniProtKB/Swiss-Prot), Q29081 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAPLGSVPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQRLLD ASTYKESYRKDMIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQETYGAVTQT VRVVATEQSRQQRGWVFIPGVDDAESECGLDDFGAFDWVIENHGDEQHLEEQLGHLIEFVHSRL hide sequence

RefSeq Acc Id:	XP_020944170 ⟸ XM_021088511
- Peptide Label:	isoform X2
- Sequence:	show sequence MSVPSSGSRAHSRSSMLRKIVEGVSQPIWLVSDTRRLSDIQWFQETYGAVTQTVRVVATEQSRQ QRGWVFIPGVDDAESECGLDDFGAFDWVIENHGDEQHLEEQLGHLIEFVHSRL hide sequence

RefSeq Acc Id:

ENSSSCP00000006964 ⟸ ENSSSCT00000007157

RefSeq Acc Id:

ENSSSCP00000076215 ⟸ ENSSSCT00000096702

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000006535	Ensembl
	ENSSSCG00000055689	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSSSCG00025029408	UniProtKB/Swiss-Prot
	ENSSSCG00035080644	UniProtKB/Swiss-Prot
	ENSSSCG00040074485	UniProtKB/Swiss-Prot
	ENSSSCG00045015312	UniProtKB/Swiss-Prot
	ENSSSCG00050020471	UniProtKB/Swiss-Prot
	ENSSSCG00055010989	UniProtKB/Swiss-Prot
	ENSSSCG00070027918	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSSSCT00000096702	ENTREZGENE
	ENSSSCT00000096702.1	UniProtKB/Swiss-Prot
	ENSSSCT00025039977.1	UniProtKB/Swiss-Prot
	ENSSSCT00035110593.1	UniProtKB/Swiss-Prot
	ENSSSCT00040102979.1	UniProtKB/Swiss-Prot
	ENSSSCT00045026000.1	UniProtKB/Swiss-Prot
	ENSSSCT00050027646.1	UniProtKB/Swiss-Prot
	ENSSSCT00055021592.1	UniProtKB/Swiss-Prot
	ENSSSCT00070056028.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Pmev_kin_anim	UniProtKB/Swiss-Prot
KEGG Report	ssc:100152301	UniProtKB/Swiss-Prot
NCBI Gene	PMVK	ENTREZGENE
PANTHER	PHOSPHOMEVALONATE KINASE	UniProtKB/Swiss-Prot
	PTHR13101	UniProtKB/Swiss-Prot
Pfam	P-mevalo_kinase	UniProtKB/Swiss-Prot
PIRSF	PMK_anim	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	F1RGP9	ENTREZGENE
	PMVK_PIG	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	F1RGP9	UniProtKB/Swiss-Prot
VGNC ID	VGNC:98835	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB