Gene: Mep1b (meprin A subunit beta) Rattus norvegicus
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Symbol: Mep1b
Name: meprin A subunit beta
Description: ENCODES a protein that exhibits metalloendopeptidase activity; identical protein binding (ortholog); INVOLVED IN toxin transport (ortholog); FOUND IN integral component of plasma membrane (ortholog); membrane (ortholog); meprin A complex (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; bisphenol A
AGR Description: Exhibits metalloendopeptidase activity; predicted to be involved in toxin transport; predicted to localize to the integral component of plasma membrane and meprin A complex; orthologous to human MEP1B (meprin A subunit beta).
Merged Description: Exhibits metalloendopeptidase activity; predicted to be involved in toxin transport; predicted to localize to the integral component of plasma membrane and meprin A complex; orthologous to human MEP1B (meprin A subunit beta); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endopeptidase-2; meprin; meprin 1 beta; meprin A beta; meprin B
Orthologs:
Homo sapiens (human) : MEP1B (meprin A subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Mep1b (meprin 1 beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mep1b (meprin A subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : MEP1B (meprin A subunit beta)
Canis lupus familiaris (dog) : MEP1B (meprin A subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mep1b (meprin A subunit beta)
Sus scrofa (pig) : MEP1B (meprin A subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01815,063,159 - 15,090,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01814,847,661 - 14,874,235 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1812,357,847 - 12,384,551 (+)NCBICelera
Cytogenetic Map18p12NCBI
RH 3.4 Map18131.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mep1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3081
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.