Srsf11 (serine and arginine rich splicing factor 11) - Rat Genome Database
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Gene: Srsf11 (serine and arginine rich splicing factor 11) Rattus norvegicus
Analyze
Symbol: Srsf11
Name: serine and arginine rich splicing factor 11
RGD ID: 1559953
Description: Predicted to have identical protein binding activity. Predicted to be involved in RNA splicing. Predicted to localize to nuclear speck. Orthologous to human SRSF11 (serine and arginine rich splicing factor 11); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC502603; MGC116323; serine/arginine-rich splicing factor 11; Sfrs11; similar to splicing factor p54; splicing factor, arginine/serine-rich 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02264,837,463 - 264,864,296 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02283,477,393 - 283,504,112 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42256,154,645 - 256,175,169 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2238,874,964 - 238,894,383 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:22658674   PMID:22681889   PMID:31505169  


Genomics

Comparative Map Data
Srsf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02264,837,463 - 264,864,296 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02283,477,393 - 283,504,112 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42256,154,645 - 256,175,169 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2238,874,964 - 238,894,383 (-)NCBICelera
Cytogenetic Map2q45NCBI
SRSF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl170,205,682 - 70,253,052 (+)EnsemblGRCh38hg38GRCh38
GRCh38170,205,696 - 70,253,052 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37170,671,379 - 70,718,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36170,443,953 - 70,490,272 (+)NCBINCBI36hg18NCBI36
Build 34170,383,385 - 70,429,705NCBI
Celera168,961,312 - 69,007,634 (+)NCBI
Cytogenetic Map1p31.1NCBI
HuRef168,782,549 - 68,828,871 (+)NCBIHuRef
CHM1_1170,786,765 - 70,833,100 (+)NCBICHM1_1
Srsf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,716,552 - 157,742,311 (-)NCBIGRCm39mm39
GRCm39 Ensembl3157,716,110 - 157,742,276 (-)Ensembl
GRCm383158,010,915 - 158,036,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3158,010,473 - 158,036,639 (-)EnsemblGRCm38mm10GRCm38
MGSCv373157,673,457 - 157,699,603 (-)NCBIGRCm37mm9NCBIm37
MGSCv363157,945,937 - 157,958,504 (-)NCBImm8
Celera3164,477,852 - 164,503,994 (-)NCBICelera
Cytogenetic Map3H4NCBI
Srsf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542321,669,471 - 21,706,327 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542321,669,925 - 21,706,260 (-)NCBIChiLan1.0ChiLan1.0
SRSF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1171,426,668 - 71,472,580 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,442,600 - 71,471,361 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0169,441,043 - 69,488,427 (+)NCBIMhudiblu_PPA_v0panPan3
SRSF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl675,464,957 - 75,492,103 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1675,473,794 - 75,495,860 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Srsf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365911,789,358 - 1,825,854 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6142,621,924 - 142,642,073 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16142,621,904 - 142,668,107 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26132,193,667 - 132,240,416 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRSF11
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12062,885,980 - 62,932,394 (-)NCBI
ChlSab1.1 Ensembl2062,883,026 - 62,916,436 (-)Ensembl
Srsf11
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474225,761,410 - 25,787,195 (-)NCBI

Position Markers
WI-18827  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02264,838,193 - 264,838,314NCBIRnor6.0
Rnor_5.02283,478,119 - 283,478,240UniSTSRnor5.0
RGSC_v3.42256,155,371 - 256,155,492UniSTSRGSC3.4
Celera2238,875,690 - 238,875,811UniSTS
Cytogenetic Map2q45UniSTS
RH143041  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02264,854,522 - 264,854,756NCBIRnor6.0
Rnor_5.02283,494,360 - 283,494,594UniSTSRnor5.0
RGSC_v3.42256,172,684 - 256,172,918UniSTSRGSC3.4
Celera2238,891,898 - 238,892,132UniSTS
RH 3.4 Map21646.11UniSTS
Cytogenetic Map2q45UniSTS
UniSTS:225095  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02264,837,514 - 264,837,617NCBIRnor6.0
Rnor_5.02283,477,440 - 283,477,543UniSTSRnor5.0
RGSC_v3.42256,154,692 - 256,154,795UniSTSRGSC3.4
Celera2238,875,011 - 238,875,114UniSTS
Cytogenetic Map2q45UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2236318496264899009Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2236318496264899009Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2228712271266435125Rat
631563Hcuc3Hepatic copper content QTL 33.87hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2245893572266435125Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2229793522266435125Rat
631514Scl8Serum cholesterol level QTL84.4blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)2231621666266435125Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2229606682264899009Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2228712271266435125Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2240679103266435125Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2228712271266435125Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2240679103266435125Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2228712271266435125Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2228712271266435125Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:180
Count of miRNA genes:132
Interacting mature miRNAs:155
Transcripts:ENSRNOT00000044236
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001035255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000044236   ⟹   ENSRNOP00000043202
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)Ensembl
RefSeq Acc Id: NM_001035255   ⟹   NP_001030332
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,627 - 247,094,168 (-)NCBI
Rnor_6.02264,837,467 - 264,857,007 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
RGSC_v3.42256,154,645 - 256,175,169 (-)RGD
Celera2238,874,964 - 238,894,383 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233540   ⟹   XP_006233602
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233541   ⟹   XP_006233603
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,295 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233542   ⟹   XP_006233604
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233543   ⟹   XP_006233605
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,353 (-)NCBI
Rnor_6.02264,837,463 - 264,864,258 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761567   ⟹   XP_008759789
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761568   ⟹   XP_008759790
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02264,837,463 - 264,864,258 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761569   ⟹   XP_008759791
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,101,354 (-)NCBI
Rnor_6.02264,837,463 - 264,864,258 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102967   ⟹   XP_038958895
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,089,896 (-)NCBI
RefSeq Acc Id: XM_039102968   ⟹   XP_038958896
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,623 - 247,089,896 (-)NCBI
RefSeq Acc Id: XR_005500353
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,627 - 247,101,460 (-)NCBI
RefSeq Acc Id: XR_005500354
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22247,074,627 - 247,101,460 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001030332   ⟸   NM_001035255
- UniProtKB: Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233604   ⟸   XM_006233542
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006233602   ⟸   XM_006233540
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006233603   ⟸   XM_006233541
- Peptide Label: isoform X3
- UniProtKB: A0A0G2QC38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233605   ⟸   XM_006233543
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008759789   ⟸   XM_008761567
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008759791   ⟸   XM_008761569
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008759790   ⟸   XM_008761568
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000043202   ⟸   ENSRNOT00000044236
RefSeq Acc Id: XP_038958895   ⟸   XM_039102967
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038958896   ⟸   XM_039102968
- Peptide Label: isoform X8
Protein Domains
RRM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691843
Promoter ID:EPDNEW_R2367
Type:initiation region
Name:Srsf11_1
Description:serine and arginine rich splicing factor 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02264,864,261 - 264,864,321EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559953 AgrOrtholog
Ensembl Genes ENSRNOG00000029592 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000043202 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044236 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381485 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SRSF11 UniProtKB/TrEMBL
KEGG Report rno:502603 UniProtKB/TrEMBL
MGC_CLONE MGC:116323 IMAGE-MGC_LOAD
NCBI Gene 502603 ENTREZGENE
PANTHER PTHR32343:SF6 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Srsf11 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2QC38 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLK1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3ZBT0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Srsf11  serine and arginine rich splicing factor 11  Srsf11  serine/arginine-rich splicing factor 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Srsf11  serine/arginine-rich splicing factor 11  Sfrs11  splicing factor, arginine/serine-rich 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Sfrs11  splicing factor, arginine/serine-rich 11  Srsf11  serine/arginine-rich splicing factor 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srsf11  serine/arginine-rich splicing factor 11  Sfrs11  splicing factor, arginine/serine-rich 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-20 Sfrs11  splicing factor, arginine/serine-rich 11  Srsf11  serine/arginine-rich splicing factor 11   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-14 Srsf11  serine/arginine-rich splicing factor 11   Sfrs11  splicing factor, arginine/serine-rich 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Sfrs11  splicing factor, arginine/serine-rich 11  LOC502603  similar to splicing factor p54  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC502603  similar to splicing factor p54      Symbol and Name status set to provisional 70820 PROVISIONAL