Wdr26 (WD repeat domain 26) - Rat Genome Database

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Gene: Wdr26 (WD repeat domain 26) Rattus norvegicus
Analyze
Symbol: Wdr26
Name: WD repeat domain 26
RGD ID: 1565589
Description: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of GID complex. Orthologous to human WDR26 (WD repeat domain 26); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498301; RGD1565589; similar to myocardial ischemic preconditioning upregulated protein 2; WD repeat-containing protein 26
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,930,282 - 92,972,061 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1392,930,285 - 92,977,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1395,435,602 - 95,477,016 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01396,835,504 - 96,876,919 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01394,011,130 - 94,052,465 (-)NCBIRnor_WKY
Rnor_6.01399,493,117 - 99,532,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,493,120 - 99,531,959 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,488,124 - 104,526,797 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,944,266 - 96,984,348 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1392,471,633 - 92,510,631 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA,ISO)
GID complex  (IBA)
mitochondrion  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)
ubiquitin ligase complex  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15378603   PMID:23625927   PMID:27797717   PMID:29253592   PMID:29911972   PMID:34981336  


Genomics

Comparative Map Data
Wdr26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,930,282 - 92,972,061 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1392,930,285 - 92,977,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1395,435,602 - 95,477,016 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01396,835,504 - 96,876,919 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01394,011,130 - 94,052,465 (-)NCBIRnor_WKY
Rnor_6.01399,493,117 - 99,532,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,493,120 - 99,531,959 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,488,124 - 104,526,797 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,944,266 - 96,984,348 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1392,471,633 - 92,510,631 (-)NCBICelera
Cytogenetic Map13q26NCBI
WDR26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381224,385,146 - 224,434,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1224,385,146 - 224,437,033 (-)EnsemblGRCh38hg38GRCh38
GRCh371224,572,848 - 224,622,499 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361222,639,815 - 222,688,335 (-)NCBINCBI36Build 36hg18NCBI36
Build 341220,879,927 - 220,928,447NCBI
Celera1197,763,775 - 197,812,936 (-)NCBICelera
Cytogenetic Map1q42.11-q42.12NCBI
HuRef1195,092,877 - 195,142,018 (-)NCBIHuRef
CHM1_11225,845,217 - 225,894,316 (-)NCBICHM1_1
T2T-CHM13v2.01223,573,956 - 223,623,646 (-)NCBIT2T-CHM13v2.0
Wdr26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391181,000,791 - 181,046,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1181,000,793 - 181,039,566 (-)EnsemblGRCm39 Ensembl
GRCm381181,173,226 - 181,220,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1181,173,228 - 181,212,001 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,103,357 - 183,142,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,014,368 - 183,048,045 (-)NCBIMGSCv36mm8
Celera1188,240,133 - 188,279,705 (-)NCBICelera
Cytogenetic Map1H4NCBI
Wdr26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955520950,502 - 986,929 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955520950,505 - 983,963 (+)NCBIChiLan1.0ChiLan1.0
WDR26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11204,861,784 - 204,911,148 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1204,861,784 - 204,914,538 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01199,853,860 - 199,903,474 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
WDR26
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1739,968,183 - 40,003,221 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl739,967,576 - 39,997,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha739,447,756 - 39,487,509 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0739,800,017 - 39,839,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl739,799,505 - 39,837,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1739,641,020 - 39,680,775 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0739,648,499 - 39,688,230 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0739,917,284 - 39,957,066 (+)NCBIUU_Cfam_GSD_1.0
Wdr26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934453,273,000 - 53,317,076 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365261,429,972 - 1,474,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1012,713,769 - 12,756,549 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11012,713,528 - 12,756,713 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21015,136,567 - 15,179,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,339,056 - 5,393,173 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660555,522,246 - 5,571,153 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr26
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248356,005,173 - 6,041,915 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248356,000,566 - 6,041,917 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
AU048745  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q32UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map13q26UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map1q54UniSTS
Cytogenetic Map1q36UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map13p13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map10q31UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map3p13UniSTS
RH130354  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,933,033 - 92,933,214 (+)MAPPERmRatBN7.2
Rnor_6.01399,495,869 - 99,496,049NCBIRnor6.0
Rnor_5.013104,490,873 - 104,491,053UniSTSRnor5.0
RGSC_v3.41396,947,015 - 96,947,195UniSTSRGSC3.4
Celera1392,474,382 - 92,474,562UniSTS
RH 3.4 Map13631.8UniSTS
Cytogenetic Map13q26UniSTS
RH130922  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,932,144 - 92,932,364 (+)MAPPERmRatBN7.2
Rnor_6.01399,494,980 - 99,495,199NCBIRnor6.0
Rnor_5.013104,489,984 - 104,490,203UniSTSRnor5.0
RGSC_v3.41396,946,126 - 96,946,345UniSTSRGSC3.4
Celera1392,473,493 - 92,473,712UniSTS
RH 3.4 Map13658.1UniSTS
Cytogenetic Map13q26UniSTS
RH140570  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,934,037 - 92,934,257 (+)MAPPERmRatBN7.2
Rnor_6.01399,496,873 - 99,497,092NCBIRnor6.0
Rnor_5.013104,491,877 - 104,492,096UniSTSRnor5.0
RGSC_v3.41396,948,019 - 96,948,238UniSTSRGSC3.4
Celera1392,475,386 - 92,475,605UniSTS
RH 3.4 Map14158.87UniSTS
Cytogenetic Map13q26UniSTS
AI179677  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,930,317 - 92,930,407 (+)MAPPERmRatBN7.2
Rnor_6.01399,493,153 - 99,493,242NCBIRnor6.0
Rnor_5.013104,488,157 - 104,488,246UniSTSRnor5.0
RGSC_v3.41396,944,299 - 96,944,388UniSTSRGSC3.4
Celera1392,471,666 - 92,471,755UniSTS
RH 3.4 Map13618.0UniSTS
Cytogenetic Map13q26UniSTS
BE104590  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,936,903 - 92,937,101 (+)MAPPERmRatBN7.2
Rnor_6.01399,499,740 - 99,499,937NCBIRnor6.0
Rnor_5.013104,494,744 - 104,494,941UniSTSRnor5.0
RGSC_v3.41396,950,886 - 96,951,083UniSTSRGSC3.4
Celera1392,478,253 - 92,478,450UniSTS
RH 3.4 Map13629.5UniSTS
Cytogenetic Map13q26UniSTS
AI103728  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,937,039 - 92,937,243 (+)MAPPERmRatBN7.2
Rnor_6.01399,499,876 - 99,500,079NCBIRnor6.0
Rnor_5.013104,494,880 - 104,495,083UniSTSRnor5.0
RGSC_v3.41396,951,022 - 96,951,225UniSTSRGSC3.4
Celera1392,478,389 - 92,478,592UniSTS
RH 3.4 Map13628.6UniSTS
Cytogenetic Map13q26UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:571
Count of miRNA genes:276
Interacting mature miRNAs:373
Transcripts:ENSRNOT00000005059
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000005059   ⟹   ENSRNOP00000005059
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,930,285 - 92,977,295 (-)Ensembl
Rnor_6.0 Ensembl1399,493,120 - 99,531,959 (-)Ensembl
RefSeq Acc Id: NM_001109081   ⟹   NP_001102551
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,930,285 - 92,969,448 (-)NCBI
Rnor_6.01399,493,120 - 99,531,959 (-)NCBI
Rnor_5.013104,488,124 - 104,526,797 (-)NCBI
RGSC_v3.41396,944,266 - 96,984,348 (-)RGD
Celera1392,471,633 - 92,510,631 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090991   ⟹   XP_038946919
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,934,125 - 92,971,691 (-)NCBI
RefSeq Acc Id: XM_039090992   ⟹   XP_038946920
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,930,282 - 92,971,691 (-)NCBI
RefSeq Acc Id: XM_039090993   ⟹   XP_038946921
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,930,282 - 92,972,059 (-)NCBI
RefSeq Acc Id: XR_005492274
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,934,125 - 92,971,691 (-)NCBI
RefSeq Acc Id: XR_005492275
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,934,125 - 92,972,061 (-)NCBI
RefSeq Acc Id: XR_005492276
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,934,125 - 92,969,221 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102551   ⟸   NM_001109081
- Sequence:
RefSeq Acc Id: ENSRNOP00000005059   ⟸   ENSRNOT00000005059
RefSeq Acc Id: XP_038946921   ⟸   XM_039090993
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946920   ⟸   XM_039090992
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946919   ⟸   XM_039090991
- Peptide Label: isoform X1
Protein Domains
CTLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LTR1-F1-model_v2 AlphaFold F1LTR1 1-514 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565589 AgrOrtholog
BioCyc Gene G2FUF-17095 BioCyc
Ensembl Genes ENSRNOG00000003723 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005059 ENTREZGENE
  ENSRNOP00000005059.6 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005059 ENTREZGENE
  ENSRNOT00000005059.6 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
InterPro CTLH_C UniProtKB/Swiss-Prot
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
NCBI Gene 498301 ENTREZGENE
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Wdr26 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE CTLH UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART CTLH UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8L2Q1C0_RAT UniProtKB/TrEMBL
  F1LTR1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Wdr26  WD repeat domain 26  RGD1565589_predicted  similar to myocardial ischemic preconditioning upregulated protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565589_predicted  similar to myocardial ischemic preconditioning upregulated protein 2 (predicted)  LOC498301  similar to myocardial ischemic preconditioning upregulated protein 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498301  similar to myocardial ischemic preconditioning upregulated protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL