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ONTOLOGY REPORT - ANNOTATIONS


Term:econazole
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Accession:CHEBI:4754 term browser browse the term
Definition:A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
Synonyms:exact_synonym: rac-1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (RS)-econazole;   1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole;   Formula=C18H15Cl3N2O;   rac-econazole
 xref: CAS:27220-47-9 "ChemIDplus";   CAS:27220-47-9 "KEGG COMPOUND";   DrugBank:DB01127;   HMDB:HMDB0015259;   KEGG:C08068;   KEGG:D03936
 xref_mesh: MESH:D004464
 xref: PMID:11065186 "Europe PMC";   PMID:15094063 "Europe PMC";   PMID:24374794 "Europe PMC";   PMID:24530389 "Europe PMC";   Reaxys:964150 "Reaxys";   Wikipedia:Econazole


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econazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Kcna3 potassium voltage-gated channel subfamily A member 3 JBrowse link 2 209,766,767 209,768,344 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 6 28,677,563 28,931,844 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6480464
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:6480464
G Ulk1 unc-51 like autophagy activating kinase 1 JBrowse link 12 51,908,105 51,934,704 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    chemical entity 19660
      chemical substance 10732
        mixture 9938
          racemate 8667
            econazole 11
              econazole nitrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic heterocyclic compound 18164
                                  heteroarene 15170
                                    monocyclic heteroarene 11624
                                      azole 10480
                                        diazole 8045
                                          imidazoles 7596
                                            1-\{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl\}imidazole 11
                                              (S)-econazole 11
                                                econazole 11
                                                  econazole nitrate 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.