Msn (moesin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Msn (moesin) Rattus norvegicus
Analyze
Symbol: Msn
Name: moesin
RGD ID: 621260
Description: Enables actin binding activity. Involved in response to alcohol. Located in several cellular components, including T-tubule; cytoplasmic side of plasma membrane; and filopodium membrane. Used to study primary biliary cholangitis. Human ortholog(s) of this gene implicated in immunodeficiency 50. Orthologous to human MSN (moesin); PARTICIPATES IN measles pathway; INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: membrane-organizing extension spike protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X65,005,546 - 65,073,512 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX65,005,458 - 65,075,129 (+)EnsemblGRCr8
mRatBN7.2X60,996,043 - 61,064,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX60,995,951 - 61,065,628 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX62,461,999 - 62,529,852 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X65,962,516 - 66,030,370 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X63,527,452 - 63,595,461 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X65,226,834 - 65,294,192 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,226,748 - 65,295,810 (+)Ensemblrn6Rnor6.0
Rnor_5.0X66,068,480 - 66,135,838 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X83,716,068 - 83,784,214 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX61,409,205 - 61,477,230 (+)NCBICelera
RGSC_v3.1X83,789,359 - 83,857,506 (+)NCBI
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aniline  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
butan-1-ol  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
carvedilol  (EXP)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (EXP,ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
dioxygen  (EXP,ISO)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenamidone  (ISO)
flavonoids  (EXP)
folic acid  (EXP,ISO)
FR900359  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
furfural  (ISO)
Ganoderic acid A  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
heparin  (EXP)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
L-methionine  (EXP,ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP,ISO)
methimazole  (EXP)
microcystin-LR  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (EXP)
naphthalene  (ISO)
nitric oxide  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phosgene  (ISO)
quercitrin  (ISO)
razoxane  (EXP)
rotenone  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sorafenib  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tanespimycin  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
troglitazone  (EXP)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
Y-27632  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ERM proteins mediate the effects of Na+/H+ exchanger (NHE1) activation in cardiac myocytes. Darmellah A, etal., Cardiovasc Res. 2009 Feb 1;81(2):294-300. doi: 10.1093/cvr/cvn320. Epub 2008 Nov 21.
2. Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility. Gatto CL, etal., J Cell Physiol. 2007 Jan;210(1):122-32.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate. Jeon S, etal., J Biol Chem 2002 May 10;277(19):16576-84.
6. Effects of ethanol withdrawal on the activity of rho-kinase in rat brain. Kurt AH, etal., Bratisl Lek Listy. 2015;116(8):490-3. doi: 10.4149/bll_2015_093.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. ERMs colocalize transiently with L1 during neocortical axon outgrowth. Mintz CD, etal., J Comp Neurol 2003 Sep 29;464(4):438-48.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Cloning and cellular localization of the rat mast cell 78-kDa protein phosphorylated in response to the mast cell "stabilizer" cromolyn. Theoharides TC, etal., J Pharmacol Exp Ther 2000 Sep;294(3):810-21.
15. Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis. Zhou Q, etal., Gut. 2006 Sep;55(9):1296-305. Epub 2006 Feb 21.
Additional References at PubMed
PMID:9472040   PMID:9890997   PMID:11728336   PMID:12082081   PMID:12360288   PMID:12519789   PMID:14625387   PMID:15031678   PMID:15634677   PMID:15819698   PMID:15922359   PMID:16502470  
PMID:16791210   PMID:17170707   PMID:17292355   PMID:17634366   PMID:18541292   PMID:19056867   PMID:19190083   PMID:19199708   PMID:19255442   PMID:19460862   PMID:19783662   PMID:20458337  
PMID:20926777   PMID:21148287   PMID:21266579   PMID:21282464   PMID:21362503   PMID:21423176   PMID:22082260   PMID:22132106   PMID:22206666   PMID:22291017   PMID:22467863   PMID:22516433  
PMID:22708623   PMID:22871113   PMID:23264465   PMID:23533145   PMID:24065547   PMID:24127566   PMID:24184478   PMID:24862762   PMID:25486435   PMID:25775275   PMID:25854562   PMID:27342875  
PMID:27405666   PMID:30448045   PMID:35352799   PMID:37569454  


Genomics

Comparative Map Data
Msn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X65,005,546 - 65,073,512 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX65,005,458 - 65,075,129 (+)EnsemblGRCr8
mRatBN7.2X60,996,043 - 61,064,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX60,995,951 - 61,065,628 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX62,461,999 - 62,529,852 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X65,962,516 - 66,030,370 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X63,527,452 - 63,595,461 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X65,226,834 - 65,294,192 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,226,748 - 65,295,810 (+)Ensemblrn6Rnor6.0
Rnor_5.0X66,068,480 - 66,135,838 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X83,716,068 - 83,784,214 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX61,409,205 - 61,477,230 (+)NCBICelera
RGSC_v3.1X83,789,359 - 83,857,506 (+)NCBI
Cytogenetic MapXq22NCBI
MSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X65,588,377 - 65,741,931 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX65,588,377 - 65,741,931 (+)Ensemblhg38GRCh38
GRCh37X64,887,521 - 64,961,793 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X64,804,236 - 64,878,518 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X64,670,531 - 64,744,813NCBI
CeleraX65,234,645 - 65,308,924 (+)NCBICelera
Cytogenetic MapXq12NCBI
HuRefX58,715,854 - 58,790,104 (+)NCBIHuRef
CHM1_1X64,780,526 - 64,854,813 (+)NCBICHM1_1
T2T-CHM13v2.0X64,014,795 - 64,168,344 (+)NCBIT2T-CHM13v2.0
Msn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X95,139,651 - 95,212,159 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX95,139,648 - 95,212,158 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X96,096,045 - 96,168,553 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX96,096,042 - 96,168,552 (+)Ensemblmm10GRCm38
MGSCv37X93,291,384 - 93,363,892 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X92,298,764 - 92,371,272 (+)NCBIMGSCv36mm8
MGSCv36X78,937,756 - 79,010,624 (+)NCBIMGSCv36mm8
CeleraX83,101,832 - 83,174,019 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX42.65NCBI
Msn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554755,301,910 - 5,370,691 (+)Ensembl
ChiLan1.0NW_0049554755,301,856 - 5,370,378 (+)NCBIChiLan1.0ChiLan1.0
MSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X65,193,477 - 65,267,583 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X65,197,098 - 65,271,188 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X54,785,309 - 54,859,364 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X64,859,691 - 64,933,014 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX64,781,550 - 64,933,292 (+)EnsemblpanPan2panpan1.1
MSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X50,708,913 - 50,775,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX50,708,704 - 50,773,762 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX41,546,746 - 41,613,249 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X51,673,014 - 51,739,539 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX51,672,882 - 51,739,537 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X49,637,614 - 49,704,123 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X50,985,533 - 51,052,067 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X50,900,835 - 50,967,356 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Msn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X51,624,794 - 51,696,281 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366352,389,823 - 2,461,930 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366352,390,390 - 2,461,870 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX51,844,156 - 51,970,107 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X51,844,197 - 51,967,674 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X58,473,234 - 58,596,676 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MSN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X55,660,262 - 55,734,605 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX55,660,234 - 55,735,191 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660832,953,269 - 3,027,796 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Msn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248981,525,388 - 1,601,539 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248981,525,795 - 1,601,402 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Msn
154 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:471
Count of miRNA genes:257
Interacting mature miRNAs:330
Transcripts:ENSRNOT00000040148
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6103585667175160Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat

Markers in Region
DXRat57  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X65,019,436 - 65,019,653 (+)Marker Load Pipeline
mRatBN7.2X61,009,935 - 61,010,152 (+)MAPPERmRatBN7.2
Rnor_6.0X65,240,745 - 65,240,961NCBIRnor6.0
Rnor_5.0X66,082,391 - 66,082,607UniSTSRnor5.0
RGSC_v3.4X83,729,950 - 83,730,293RGDRGSC3.4
RGSC_v3.4X83,729,959 - 83,730,175UniSTSRGSC3.4
CeleraX61,423,096 - 61,423,312UniSTS
RGSC_v3.1X83,803,251 - 83,803,467RGD
RH 3.4 Map41029.3UniSTS
RH 3.4 Map41029.3RGD
SHRSP x BN MapX17.17UniSTS
SHRSP x BN MapX17.17RGD
FHH x ACI MapX22.4799RGD
Cytogenetic MapXq31UniSTS
RH128018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X61,065,298 - 61,065,479 (+)MAPPERmRatBN7.2
Rnor_6.0X65,295,480 - 65,295,660NCBIRnor6.0
Rnor_5.0X66,137,126 - 66,137,306UniSTSRnor5.0
RGSC_v3.4X83,785,502 - 83,785,682UniSTSRGSC3.4
CeleraX61,478,518 - 61,478,698UniSTS
RH 3.4 Map41028.88UniSTS
Cytogenetic MapXq31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000076178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX65,291,022 - 65,291,353 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076181   ⟹   ENSRNOP00000068359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX65,005,458 - 65,075,129 (+)Ensembl
mRatBN7.2 EnsemblX60,995,951 - 61,065,626 (+)Ensembl
Rnor_6.0 EnsemblX65,226,748 - 65,295,810 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX65,226,761 - 65,281,991 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093499   ⟹   ENSRNOP00000076229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX65,050,550 - 65,068,414 (+)Ensembl
mRatBN7.2 EnsemblX61,040,259 - 61,058,913 (+)Ensembl
Rnor_6.0 EnsemblX65,271,366 - 65,293,928 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103579   ⟹   ENSRNOP00000082468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX61,040,259 - 61,065,628 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106726   ⟹   ENSRNOP00000091455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX61,040,537 - 61,065,628 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117318   ⟹   ENSRNOP00000080802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX65,005,495 - 65,075,129 (+)Ensembl
mRatBN7.2 EnsemblX60,995,956 - 61,065,624 (+)Ensembl
RefSeq Acc Id: NM_030863   ⟹   NP_110490
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X65,005,546 - 65,073,512 (+)NCBI
mRatBN7.2X60,996,043 - 61,064,011 (+)NCBI
Rnor_6.0X65,226,834 - 65,294,192 (+)NCBI
Rnor_5.0X66,068,480 - 66,135,838 (+)NCBI
RGSC_v3.4X83,716,068 - 83,784,214 (+)RGD
CeleraX61,409,205 - 61,477,230 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_110490 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB61666 (Get FASTA)   NCBI Sequence Viewer  
  EDL95973 (Get FASTA)   NCBI Sequence Viewer  
  EDL95974 (Get FASTA)   NCBI Sequence Viewer  
  EDL95975 (Get FASTA)   NCBI Sequence Viewer  
  EDL95976 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068359
GenBank Protein O35763 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_110490   ⟸   NM_030863
- UniProtKB: O35763 (UniProtKB/Swiss-Prot),   A6IQ37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076229   ⟸   ENSRNOT00000093499
Ensembl Acc Id: ENSRNOP00000068359   ⟸   ENSRNOT00000076181
Ensembl Acc Id: ENSRNOP00000082468   ⟸   ENSRNOT00000103579
Ensembl Acc Id: ENSRNOP00000080802   ⟸   ENSRNOT00000117318
Ensembl Acc Id: ENSRNOP00000091455   ⟸   ENSRNOT00000106726
Protein Domains
FERM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35763-F1-model_v2 AlphaFold O35763 1-577 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701850
Promoter ID:EPDNEW_R12374
Type:initiation region
Name:Msn_1
Description:moesin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X65,226,746 - 65,226,806EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621260 AgrOrtholog
BioCyc Gene G2FUF-2194 BioCyc
Ensembl Genes ENSRNOG00000030118 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000076181 ENTREZGENE
Gene3D-CATH 1.20.5.450 UniProtKB/Swiss-Prot
  1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  6.10.360.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  ERM UniProtKB/Swiss-Prot
  ERM_C_dom UniProtKB/Swiss-Prot
  ERM_FERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  Moesin_tail_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:81521 UniProtKB/Swiss-Prot
NCBI Gene 81521 ENTREZGENE
PANTHER PTHR23281 UniProtKB/Swiss-Prot
Pfam ERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
PhenoGen Msn PhenoGen
PIRSF ERM UniProtKB/Swiss-Prot
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE FERM_1 UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000030118 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF48678 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A096MK30_RAT UniProtKB/TrEMBL
  A0A1W2Q6E9_RAT UniProtKB/TrEMBL
  A0A8I5ZR49_RAT UniProtKB/TrEMBL
  A0A8I5ZUJ9_RAT UniProtKB/TrEMBL
  A0A8I6ADR3_RAT UniProtKB/TrEMBL
  A6IQ37 ENTREZGENE, UniProtKB/TrEMBL
  A6IQ38_RAT UniProtKB/TrEMBL
  A6IQ39_RAT UniProtKB/TrEMBL
  A6IQ40_RAT UniProtKB/TrEMBL
  MOES_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Msn  moesin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Msn  moesin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized on the inner side of the plasma membrane 727296
gene_physical_interaction interacts with beta-actin 727296
gene_protein phosphorylated at the threonine 558 residue 633786