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Gene: Adcy2 (adenylate cyclase 2) Rattus norvegicus
Symbol: Adcy2
Name: adenylate cyclase 2
Description: Exhibits several functions, including G-protein beta/gamma-subunit complex binding activity; adenylate cyclase binding activity; and metal ion binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and cellular response to forskolin. Localizes to the integral component of plasma membrane; membrane raft; and protein-containing complex. Orthologous to human ADCY2 (adenylate cyclase 2); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; endothelin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 4,4'-sulfonyldiphenol; acrylamide.
Type: protein-coding
Also known as: AC2; adenylate cyclase 2 (brain); adenylate cyclase type 2; adenylate cyclase type II; adenylyl cyclase 2; ATP pyrophosphate-lyase 2
Homo sapiens (human) : ADCY2 (adenylate cyclase 2)  HGNC  Alliance
Mus musculus (house mouse) : Adcy2 (adenylate cyclase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy2 (adenylate cyclase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY2 (adenylate cyclase 2)
Canis lupus familiaris (dog) : ADCY2 (adenylate cyclase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy2 (adenylate cyclase 2)
Sus scrofa (pig) : ADCY2 (adenylate cyclase 2)
Chlorocebus sabaeus (green monkey) : ADCY2 (adenylate cyclase 2)
Heterocephalus glaber (naked mole-rat) : Adcy2 (adenylate cyclase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0137,043,071 - 37,698,390 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl137,507,276 - 37,698,390 (+)Ensembl
Rnor_5.0139,075,253 - 39,080,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0138,434,800 - 39,001,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4174,543,466 - 5,040,433 (+)NCBIRGSC3.4rn4RGSC3.4
Celera132,960,049 - 33,391,637 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adcy2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619965
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.