Pcbd1 (pterin-4 alpha-carbinolamine dehydratase 1) - Rat Genome Database

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Gene: Pcbd1 (pterin-4 alpha-carbinolamine dehydratase 1) Rattus norvegicus
Analyze
Symbol: Pcbd1
Name: pterin-4 alpha-carbinolamine dehydratase 1
RGD ID: 3263
Description: Enables 4-alpha-hydroxytetrahydrobiopterin dehydratase activity and transcription coactivator activity. Involved in L-phenylalanine metabolic process. Acts upstream of or within positive regulation of transcription, DNA-templated and regulation of protein binding activity. Located in nucleus. Orthologous to human PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4-alpha-hydroxy-tetrahydropterin dehydratase; 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha; 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1); DCOH; dimerization cofactor of hepatocyte nuclear factor 1-alpha; dimerization cofactor of hepatocyte nuclear factor-1-alpha; dimerization cofactor of HNF1; PCBD; PCD; phenylalanine hydroxylase-stimulating protein; PHS; pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1; pterin carbinolamine dehydratase; pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha; pterin-4-alpha-carbinolamine dehydratase; TCF1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22029,037,545 - 29,044,322 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2028,953,864 - 29,044,292 (+)Ensembl
mRatBN7.2 Ensembl2028,953,864 - 29,044,321 (+)Ensembl
Rnor_6.02030,689,690 - 30,696,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2030,690,810 - 30,696,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,484,965 - 32,491,740 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,448,703 - 28,454,184 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12028,462,435 - 28,467,964 (+)NCBI
Celera2030,472,263 - 30,477,776 (+)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (IEA)
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IPI,ISO)

References

Additional References at PubMed
PMID:7744010   PMID:8444860   PMID:8897596   PMID:9865610   PMID:15182178   PMID:16189514   PMID:19056867   PMID:21047120   PMID:21516116   PMID:23376485   PMID:23533145   PMID:25416956  


Genomics

Comparative Map Data
Pcbd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22029,037,545 - 29,044,322 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2028,953,864 - 29,044,292 (+)Ensembl
mRatBN7.2 Ensembl2028,953,864 - 29,044,321 (+)Ensembl
Rnor_6.02030,689,690 - 30,696,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2030,690,810 - 30,696,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,484,965 - 32,491,740 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,448,703 - 28,454,184 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12028,462,435 - 28,467,964 (+)NCBI
Celera2030,472,263 - 30,477,776 (+)NCBICelera
Cytogenetic Map20q11NCBI
PCBD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381070,882,280 - 70,888,565 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1070,882,280 - 70,888,565 (-)EnsemblGRCh38hg38GRCh38
GRCh371072,642,037 - 72,648,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361072,313,273 - 72,318,547 (-)NCBINCBI36hg18NCBI36
Celera1065,925,552 - 65,930,826 (-)NCBI
Cytogenetic Map10q22.1NCBI
HuRef1066,637,269 - 66,642,544 (-)NCBIHuRef
CHM1_11072,926,052 - 72,931,326 (-)NCBICHM1_1
T2T-CHM13v2.01071,752,084 - 71,758,371 (-)NCBI
Pcbd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391060,925,110 - 60,930,108 (+)NCBIGRCm39mm39
GRCm39 Ensembl1060,925,110 - 60,930,103 (+)Ensembl
GRCm381061,089,331 - 61,094,329 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,089,331 - 61,094,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv371060,552,091 - 60,557,077 (+)NCBIGRCm37mm9NCBIm37
MGSCv361060,484,716 - 60,489,676 (+)NCBImm8
Celera1062,189,905 - 62,194,954 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.14NCBI
Pcbd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,482,589 - 20,488,249 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,482,589 - 20,487,337 (+)NCBIChiLan1.0ChiLan1.0
PCBD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11069,877,545 - 69,884,030 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,878,773 - 69,881,174 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01067,353,903 - 67,359,073 (-)NCBIMhudiblu_PPA_v0panPan3
PCBD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,719,863 - 21,723,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,719,863 - 21,721,574 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,854,056 - 21,858,488 (-)NCBI
ROS_Cfam_1.0421,997,912 - 22,002,345 (-)NCBI
ROS_Cfam_1.0 Ensembl421,997,904 - 22,002,274 (-)Ensembl
UMICH_Zoey_3.1421,893,535 - 21,897,967 (-)NCBI
UNSW_CanFamBas_1.0422,098,728 - 22,103,182 (-)NCBI
UU_Cfam_GSD_1.0422,451,020 - 22,455,453 (-)NCBI
Pcbd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,351,220 - 59,355,096 (+)NCBI
SpeTri2.0NW_0049365217,843,945 - 7,847,827 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCBD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,772,835 - 73,807,281 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,769,339 - 73,807,278 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,648,886 - 79,655,375 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PCBD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1960,417,301 - 60,422,313 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604821,141,594 - 21,146,607 (+)NCBIVero_WHO_p1.0
Pcbd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247544,893,868 - 4,898,363 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247544,893,868 - 4,898,410 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH128638  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22029,044,003 - 29,044,188 (+)MAPPERmRatBN7.2
Rnor_6.02030,696,147 - 30,696,331NCBIRnor6.0
Rnor_5.02032,491,422 - 32,491,606UniSTSRnor5.0
RGSC_v3.42028,453,876 - 28,454,060UniSTSRGSC3.4
Celera2030,477,459 - 30,477,643UniSTS
Cytogenetic Map20q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
4889870Pur30Proteinuria QTL 30190.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:199
Count of miRNA genes:133
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000000687
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 10 41 41 41 42 35 20 3
Low 33 16 19 8 11 32 21 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000687   ⟹   ENSRNOP00000000687
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2029,041,484 - 29,044,321 (+)Ensembl
Rnor_6.0 Ensembl2030,690,810 - 30,696,476 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102353   ⟹   ENSRNOP00000094935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2029,038,844 - 29,044,321 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107746   ⟹   ENSRNOP00000086732
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2029,037,483 - 29,044,321 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115927   ⟹   ENSRNOP00000080781
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2028,953,864 - 29,044,292 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000120036   ⟹   ENSRNOP00000085944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2028,953,864 - 29,044,292 (+)Ensembl
RefSeq Acc Id: NM_001007601   ⟹   NP_001007602
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22029,038,806 - 29,044,321 (+)NCBI
Rnor_6.02030,690,951 - 30,696,464 (+)NCBI
Rnor_5.02032,484,965 - 32,491,740 (+)NCBI
RGSC_v3.42028,448,703 - 28,454,184 (+)RGD
Celera2030,472,263 - 30,477,776 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256414   ⟹   XP_006256476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22029,037,545 - 29,044,322 (+)NCBI
Rnor_6.02030,689,690 - 30,696,465 (+)NCBI
Rnor_5.02032,484,965 - 32,491,740 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001007602 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256476 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40609 (Get FASTA)   NCBI Sequence Viewer  
  CAA06587 (Get FASTA)   NCBI Sequence Viewer  
  EDL93037 (Get FASTA)   NCBI Sequence Viewer  
  P61459 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001007602   ⟸   NM_001007601
- UniProtKB: P61459 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256476   ⟸   XM_006256414
- Peptide Label: isoform X1
- UniProtKB: P61459 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000000687   ⟸   ENSRNOT00000000687
RefSeq Acc Id: ENSRNOP00000080781   ⟸   ENSRNOT00000115927
RefSeq Acc Id: ENSRNOP00000086732   ⟸   ENSRNOT00000107746
RefSeq Acc Id: ENSRNOP00000094935   ⟸   ENSRNOT00000102353
RefSeq Acc Id: ENSRNOP00000085944   ⟸   ENSRNOT00000120036

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61459-F1-model_v2 AlphaFold P61459 1-104 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701599
Promoter ID:EPDNEW_R12122
Type:initiation region
Name:Pcbd1_1
Description:pterin-4 alpha-carbinolamine dehydratase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02030,690,963 - 30,691,023EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3263 AgrOrtholog
BioCyc Gene G2FUF-3730 BioCyc
BioCyc Pathway PWY-8099 [tetrahydropteridine recycling] BioCyc
Ensembl Genes ENSRNOG00000000566 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000067614 Ensembl, ENTREZGENE
Ensembl Protein ENSRNOP00000000687 UniProtKB/Swiss-Prot
  ENSRNOP00000080781 ENTREZGENE
Ensembl Transcript ENSRNOT00000000687 UniProtKB/Swiss-Prot
  ENSRNOT00000115927 ENTREZGENE
Gene3D-CATH 3.30.1360.20 UniProtKB/Swiss-Prot
InterPro PCD_sf UniProtKB/Swiss-Prot
  Pterin_deHydtase UniProtKB/Swiss-Prot
KEGG Report rno:29700 UniProtKB/Swiss-Prot
NCBI Gene 29700 ENTREZGENE
PANTHER PTHR12599 UniProtKB/Swiss-Prot
Pfam Pterin_4a UniProtKB/Swiss-Prot
PhenoGen Pcbd1 PhenoGen
Superfamily-SCOP SSF55248 UniProtKB/Swiss-Prot
UniProt P61459 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P70519 UniProtKB/Swiss-Prot
  P80095 UniProtKB/Swiss-Prot
  Q9D930 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Pcbd1  pterin-4 alpha-carbinolamine dehydratase 1  Pcbd1  pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-26 Pcbd1  pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha  Pcbd1  pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-08-22 Pcbd1  pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1  Pcbd  6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)  Name updated 1299863 APPROVED
2004-09-10 Pcbd  6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)    6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha  Name updated 1299863 APPROVED
2002-06-10 Pcbd  6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha      Name updated 70584 APPROVED