Myo16 (myosin XVI) - Rat Genome Database

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Gene: Myo16 (myosin XVI) Rattus norvegicus
Analyze
Symbol: Myo16
Name: myosin XVI
RGD ID: 621561
Description: Enables actin filament binding activity and protein phosphatase binding activity. Involved in cerebellum development; negative regulation of G1/S transition of mitotic cell cycle; and negative regulation of cell population proliferation. Located in nucleoplasm; perinuclear region of cytoplasm; and plasma membrane. Part of myosin complex. Orthologous to human MYO16 (myosin XVI); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Loc192253; myosin heavy chain Myr 8; myosin-XVI; Myr8; neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3; unconventional myosin-16; unconventional myosin-XVI
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81685,586,428 - 86,066,537 (-)NCBIGRCr8
mRatBN7.21678,884,405 - 79,364,445 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1678,884,406 - 79,248,388 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1684,164,793 - 84,528,736 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01687,617,465 - 87,981,387 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01682,861,492 - 83,225,010 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01684,575,149 - 85,177,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1684,575,150 - 84,939,323 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01684,230,049 - 84,387,681 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01684,026,826 - 84,196,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41683,812,189 - 84,174,521 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11683,798,041 - 84,160,561 (-)NCBI
Celera1676,676,597 - 77,035,726 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
myosin complex  (IBA,IDA,IEA)
nucleoplasm  (IBA,IDA,ISO)
perinuclear region of cytoplasm  (IBA,IDA,ISO)
plasma membrane  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression. Cameron RS, etal., Cell Motil Cytoskeleton. 2007 Jan;64(1):19-48.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1. Patel KG, etal., J Neurosci 2001 Oct 15;21(20):7954-68.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16025302   PMID:21946561   PMID:23596177  


Genomics

Comparative Map Data
Myo16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81685,586,428 - 86,066,537 (-)NCBIGRCr8
mRatBN7.21678,884,405 - 79,364,445 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1678,884,406 - 79,248,388 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1684,164,793 - 84,528,736 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01687,617,465 - 87,981,387 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01682,861,492 - 83,225,010 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01684,575,149 - 85,177,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1684,575,150 - 84,939,323 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01684,230,049 - 84,387,681 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01684,026,826 - 84,196,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41683,812,189 - 84,174,521 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11683,798,041 - 84,160,561 (-)NCBI
Celera1676,676,597 - 77,035,726 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
MYO16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813108,495,716 - 109,208,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13108,596,152 - 109,208,005 (+)EnsemblGRCh38hg38GRCh38
GRCh3713109,248,253 - 109,860,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613108,046,501 - 108,658,356 (+)NCBINCBI36Build 36hg18NCBI36
Celera1390,093,241 - 90,704,849 (+)NCBICelera
Cytogenetic Map13q33.3NCBI
HuRef1389,841,420 - 90,459,347 (+)NCBIHuRef
CHM1_113109,217,125 - 109,828,656 (+)NCBICHM1_1
T2T-CHM13v2.013107,723,546 - 108,435,400 (+)NCBIT2T-CHM13v2.0
Myo16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39810,203,911 - 10,684,742 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl810,203,911 - 10,684,742 (+)EnsemblGRCm39 Ensembl
GRCm38810,153,911 - 10,634,742 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl810,153,911 - 10,634,742 (+)EnsemblGRCm38mm10GRCm38
MGSCv37810,153,923 - 10,633,950 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36810,153,883 - 10,634,716 (+)NCBIMGSCv36mm8
Celera810,328,629 - 10,808,123 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map84.77NCBI
MYO16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214110,112,484 - 110,698,180 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113108,792,576 - 109,377,691 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01389,754,451 - 90,338,658 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113108,927,287 - 109,474,930 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13108,922,993 - 109,473,752 (+)Ensemblpanpan1.1panPan2
MYO16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12257,313,714 - 57,794,415 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2257,198,283 - 57,648,949 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2257,085,190 - 57,565,676 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02257,839,484 - 58,412,897 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12257,435,509 - 57,915,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02257,308,927 - 57,905,949 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02257,461,062 - 57,942,253 (+)NCBIUU_Cfam_GSD_1.0
Myo16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945192,377,582 - 192,794,647 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364723,212,773 - 3,574,114 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364723,157,508 - 3,548,164 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11175,739,783 - 76,271,958 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21183,414,995 - 83,584,583 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYO16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1386,850,362 - 87,550,840 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604643,511,471 - 44,211,261 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247932,956,643 - 3,399,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myo16
4313 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:657
Count of miRNA genes:268
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000022742
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat

Markers in Region
RH138613  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21678,965,558 - 78,965,743 (+)MAPPERmRatBN7.2
Rnor_6.01684,656,213 - 84,656,397NCBIRnor6.0
Rnor_5.01684,107,935 - 84,108,119UniSTSRnor5.0
RGSC_v3.41683,893,463 - 83,893,647UniSTSRGSC3.4
Celera1676,757,844 - 76,758,028UniSTS
RH 3.4 Map16760.5UniSTS
Cytogenetic Map16q12.5UniSTS
BF388471  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21678,884,581 - 78,884,794 (+)MAPPERmRatBN7.2
Rnor_6.01684,575,326 - 84,575,538NCBIRnor6.0
Rnor_5.01684,027,002 - 84,027,214UniSTSRnor5.0
RGSC_v3.41683,812,365 - 83,812,577UniSTSRGSC3.4
Celera1676,676,773 - 76,676,985UniSTS
RH 3.4 Map16762.4UniSTS
Cytogenetic Map16q12.5UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 54
Low 1 35 2 2 2 20 24 1 2
Below cutoff 1 20 7 18 7 5 8 34 17 10 5

Sequence


RefSeq Acc Id: ENSRNOT00000022742   ⟹   ENSRNOP00000022741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1678,884,406 - 79,248,388 (-)Ensembl
Rnor_6.0 Ensembl1684,575,150 - 84,939,323 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1678,884,406 - 79,248,388 (-)Ensembl
Rnor_6.0 Ensembl1684,648,540 - 84,939,323 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099053   ⟹   ENSRNOP00000096592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1678,884,406 - 79,248,388 (-)Ensembl
RefSeq Acc Id: NM_138893   ⟹   NP_620248
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81685,586,429 - 85,950,368 (-)NCBI
mRatBN7.21678,884,406 - 79,248,388 (-)NCBI
Rnor_6.01684,575,150 - 84,939,323 (-)NCBI
Rnor_5.01684,026,826 - 84,196,088 (-)NCBI
Rnor_5.01684,230,049 - 84,387,681 (-)NCBI
RGSC_v3.41683,812,189 - 84,174,521 (-)RGD
Celera1676,676,597 - 77,035,726 (-)RGD
Sequence:
RefSeq Acc Id: XM_008771384   ⟹   XP_008769606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81685,586,428 - 85,974,200 (-)NCBI
mRatBN7.21678,884,405 - 79,272,216 (-)NCBI
Rnor_6.01684,575,149 - 84,963,529 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599990   ⟹   XP_017455479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81685,586,428 - 86,066,537 (-)NCBI
mRatBN7.21678,884,405 - 79,364,445 (-)NCBI
Rnor_6.01684,575,149 - 85,177,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094188   ⟹   XP_038950116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81685,586,428 - 85,974,200 (-)NCBI
mRatBN7.21678,884,405 - 79,272,218 (-)NCBI
RefSeq Acc Id: NP_620248   ⟸   NM_138893
- UniProtKB: Q9QXI0 (UniProtKB/Swiss-Prot),   Q9ERC1 (UniProtKB/Swiss-Prot),   A6IWR4 (UniProtKB/TrEMBL),   A0A8I6ANW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769606   ⟸   XM_008771384
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ANW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455479   ⟸   XM_017599990
- Peptide Label: isoform X3
- UniProtKB: Q9QXI0 (UniProtKB/Swiss-Prot),   Q9ERC1 (UniProtKB/Swiss-Prot),   A6IWR4 (UniProtKB/TrEMBL),   A0A8I6ANW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022741   ⟸   ENSRNOT00000022742
RefSeq Acc Id: XP_038950116   ⟸   XM_039094188
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ANW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096592   ⟸   ENSRNOT00000099053
Protein Domains
IQ   Myosin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERC1-F1-model_v2 AlphaFold Q9ERC1 1-1912 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621561 AgrOrtholog
BioCyc Gene G2FUF-10617 BioCyc
Ensembl Genes ENSRNOG00000016483 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055014411 UniProtKB/Swiss-Prot
  ENSRNOG00060003978 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022742.4 UniProtKB/Swiss-Prot
  ENSRNOT00000076341.2 UniProtKB/TrEMBL
  ENSRNOT00000099053.1 UniProtKB/TrEMBL
  ENSRNOT00055024752 UniProtKB/Swiss-Prot
  ENSRNOT00060006656 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYSc_Myo16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NYAP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:192253 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 192253 ENTREZGENE
PANTHER UNCONVENTIONAL MYOSIN-XVI UniProtKB/Swiss-Prot
  UNCONVENTIONAL MYOSIN-XVI UniProtKB/Swiss-Prot
  UNCONVENTIONAL MYOSIN-XVI UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-XVI UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NYAP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myo16 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016483 RatGTEx
  ENSRNOG00055014411 RatGTEx
  ENSRNOG00060003978 RatGTEx
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ANW7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATL1_RAT UniProtKB/TrEMBL
  A6IWR4 ENTREZGENE, UniProtKB/TrEMBL
  MYO16_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9QXI0 ENTREZGENE
UniProt Secondary Q9QXI0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-09-11 Myo16  myosin XVI  Myr8  myosin heavy chain Myr 8  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-01-20 Myr8  myosin heavy chain Myr 8  Loc192253    Symbol updated 1299863 APPROVED
2002-08-07 Loc192253  myosin heavy chain Myr 8      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains head domain contains a large N-terminal extension composed of multiple ankyrin repeats 633234
gene_physical_interaction associated with the protein phosphatase catalytic subunits 1alpha and 1gamma1; binds to F-actin in an ATP-sensitive manner 633234