Gene: Rad18 (RAD18 E3 ubiquitin protein ligase) Rattus norvegicus
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Symbol: Rad18
Name: RAD18 E3 ubiquitin protein ligase
Description: ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); negative regulation of cell death (ortholog); negative regulation of DNA recombination (ortholog); FOUND IN centrosome (ortholog); chromatin (ortholog); nuclear body (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aflatoxin B1; bisphenol A
AGR Description: Predicted to have several functions, including Y-form DNA binding activity, identical protein binding activity, and polyubiquitin modification-dependent protein binding activity; predicted to be involved in several processes, including negative regulation of DNA recombination, negative regulation of cell death, and protein ubiquitination; predicted to localize to several cellular components, including the Rad6-Rad18 complex and intracellular organelle; orthologous to human RAD18 (RAD18 E3 ubiquitin protein ligase).
Merged Description: Predicted to have several functions, including Y-form DNA binding activity, identical protein binding activity, and polyubiquitin modification-dependent protein binding activity; predicted to be involved in several processes, including negative regulation of DNA recombination, negative regulation of cell death, and protein ubiquitination; predicted to localize to several cellular components, including the Rad6-Rad18 complex and intracellular organelle; orthologous to human RAD18 (RAD18 E3 ubiquitin protein ligase); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase RAD18; LOC362412; MGC156682; RAD18 homolog; RAD18 homolog (S. cerevisiae)
Orthologs:
Homo sapiens (human) : RAD18 (RAD18 E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Rad18 (RAD18 E3 ubiquitin protein ligase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rad18 (RAD18 E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : RAD18 (RAD18 E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : RAD18 (RAD18 E3 ubiquitin protein ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rad18 (RAD18 E3 ubiquitin protein ligase)
Sus scrofa (pig) : RAD18 (RAD18 E3 ubiquitin protein ligase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04144,537,329 - 144,620,606 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04207,837,216 - 207,920,089 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44148,452,664 - 148,543,743 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14148,697,688 - 148,788,534 (-)NCBI
Celera4134,304,974 - 134,388,922 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rad18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306993
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.