Pdyn (prodynorphin) - Rat Genome Database

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Gene: Pdyn (prodynorphin) Rattus norvegicus
Symbol: Pdyn
Name: prodynorphin
RGD ID: 62054
Description: Predicted to enable opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Located in neuronal cell body. Is active in neuronal dense core vesicle lumen and synaptic vesicle. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 23 and temporal lobe epilepsy. Orthologous to human PDYN (prodynorphin); INTERACTS WITH (R,R)-tramadol; (S)-amphetamine; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-neoendorphin-dynorphin; preprodynorphin; proenkephalin B; proenkephalin-B
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.23116,900,990 - 116,913,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,900,992 - 116,913,334 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,798,229 - 120,810,577 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03129,393,853 - 129,406,201 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03127,054,324 - 127,066,672 (-)NCBIRnor_WKY
Rnor_6.03122,194,327 - 122,206,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,194,329 - 122,206,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,809,688 - 127,822,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,291,025 - 117,303,367 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,196,597 - 117,208,923 (-)NCBI
Celera3115,716,443 - 115,728,785 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R)-tramadol  (EXP)
(S)-amphetamine  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP)
2-hydroxypropanoic acid  (EXP)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
alpha-Neoendorphin  (EXP)
amiodarone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP,ISO)
baclofen  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP,ISO)
cisplatin  (ISO)
cocaine  (EXP,ISO)
corticosterone  (EXP,ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diazepam  (EXP)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Dynorphin B  (EXP)
entinostat  (ISO)
epoxomicin  (EXP,ISO)
ethanol  (ISO)
fentanyl  (EXP)
fluoxetine  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
ginsenoside Re  (ISO)
glyphosate  (EXP)
heroin  (ISO)
hydrogen peroxide  (ISO)
kainic acid  (EXP)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
maneb  (EXP)
methamphetamine  (EXP,ISO)
methoxychlor  (EXP)
morphine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
Nandrolone decanoate  (EXP)
Norbinaltorphimine  (ISO)
oxidopamine  (EXP,ISO)
Oxymorphone  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentobarbital  (EXP)
pirinixic acid  (ISO)
potassium atom  (ISO)
prochloraz  (EXP)
rac-lactic acid  (EXP)
raloxifene  (EXP)
resveratrol  (ISO)
ritanserin  (EXP)
SB 431542  (ISO)
scopolamine  (EXP,ISO)
SL-327  (EXP)
sodium arsenite  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
tramadol  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
U69593  (EXP)
valproic acid  (EXP,ISO)
vanoxerine dihydrochloride  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function


References - curated
# Reference Title Reference Citation
1. Sequence and expression of the rat prodynorphin gene. Civelli O, etal., Proc Natl Acad Sci U S A 1985 Jun;82(12):4291-5.
2. Characterization of the rat prodynorphin gene. Douglass J, etal., Mol Endocrinol 1989 Dec;3(12):2070-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens. Hubert GW and Kuhar MJ, Neuropeptides. 2006 Dec;40(6):409-15. Epub 2006 Oct 24.
5. Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats. Jolivalt CG, etal., Diabetologia. 2006 Nov;49(11):2775-85. Epub 2006 Aug 19.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Expression of the prodynorphin gene after experimental brain injury and its role in behavioral dysfunction. Redell JB, etal., Exp Biol Med (Maywood) 2003 Mar;228(3):261-9.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. A functional polymorphism in the prodynorphin gene promotor is associated with temporal lobe epilepsy. Stogmann E, etal., Ann Neurol 2002 Feb;51(2):260-3.
14. Dynorphin-immunoreactive terminals in the rat nucleus accumbens: cellular sites for modulation of target neurons and interactions with catecholamine afferents. Van Bockstaele EJ, etal., J Comp Neurol. 1994 Mar 1;341(1):1-15. doi: 10.1002/cne.903410102.
15. Further studies on possible dynorphin involvement in the ovulatory luteinizing hormone surge in the proestrous rat. Zhang Q, etal., Endocrine 2002 Aug;18(3):231-8.
Additional References at PubMed
PMID:8276115   PMID:9047294   PMID:12373547   PMID:14960343   PMID:14997015   PMID:15300902   PMID:15894804   PMID:16966485   PMID:17401159   PMID:17722034   PMID:18381633   PMID:18472331  
PMID:20531238   PMID:20728507   PMID:20973986   PMID:21171319   PMID:21723305   PMID:21958458   PMID:22508514   PMID:22641014   PMID:22698692   PMID:23391862   PMID:23877505   PMID:23959730  
PMID:24021806   PMID:24231353   PMID:24816773   PMID:25766322   PMID:27072528   PMID:27074815   PMID:30207304   PMID:30218420   PMID:31155522   PMID:33908346   PMID:36244036  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.23116,900,990 - 116,913,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,900,992 - 116,913,334 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,798,229 - 120,810,577 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03129,393,853 - 129,406,201 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03127,054,324 - 127,066,672 (-)NCBIRnor_WKY
Rnor_6.03122,194,327 - 122,206,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,194,329 - 122,206,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,809,688 - 127,822,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,291,025 - 117,303,367 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,196,597 - 117,208,923 (-)NCBI
Celera3115,716,443 - 115,728,785 (-)NCBICelera
Cytogenetic Map3q36NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38201,978,756 - 1,994,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl201,978,757 - 1,994,285 (-)EnsemblGRCh38hg38GRCh38
GRCh37201,959,402 - 1,974,931 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,907,402 - 1,922,702 (-)NCBINCBI36Build 36hg18NCBI36
Build 34201,907,402 - 1,922,702NCBI
Celera202,023,375 - 2,038,860 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,909,347 - 1,924,873 (-)NCBIHuRef
CHM1_1201,959,620 - 1,975,149 (-)NCBICHM1_1
T2T-CHM13v2.0202,008,889 - 2,024,418 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392129,528,469 - 129,541,858 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,528,485 - 129,541,764 (-)EnsemblGRCm39 Ensembl
GRCm382129,686,549 - 129,699,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,686,565 - 129,699,844 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,513,737 - 129,515,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,378,007 - 129,391,274 (-)NCBIMGSCv36mm8
Celera2130,916,433 - 130,918,300 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495541513,106,062 - 13,119,515 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,106,087 - 13,119,497 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1202,969,613 - 2,985,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,092,171 - 2,108,141 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,856,850 - 1,872,452 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl201,856,850 - 1,872,452 (-)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.12419,043,955 - 19,057,413 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2419,053,870 - 19,056,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,871,870 - 18,885,766 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02419,500,321 - 19,514,217 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2419,498,268 - 19,514,210 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12419,056,568 - 19,070,465 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,167,367 - 19,181,264 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02419,495,948 - 19,509,844 (+)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024408640168,127,664 - 168,140,097 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648516,559,217 - 16,571,678 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648516,559,371 - 16,571,461 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1733,505,079 - 33,521,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11733,505,075 - 33,521,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1254,535,516 - 54,551,085 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl254,535,240 - 54,551,104 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666087951,337 - 967,337 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_0046247413,237,942 - 3,253,503 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,239,101 - 3,253,507 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Pdyn
74 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:425
Count of miRNA genes:226
Interacting mature miRNAs:282
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Medium 7 26 6
Low 1 40 16 28
Below cutoff 3 21 18 10 9 10 3 3 6 2 6 6 3


Reference Sequences
RefSeq Acc Id: ENSRNOT00000037576   ⟹   ENSRNOP00000038921
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3116,900,992 - 116,913,334 (-)Ensembl
Rnor_6.0 Ensembl3122,194,329 - 122,206,671 (-)Ensembl
RefSeq Acc Id: NM_019374   ⟹   NP_062247
RefSeq Status: VALIDATED
Rat AssemblyChrPosition (strand)Source
mRatBN7.23116,900,992 - 116,913,334 (-)NCBI
Rnor_6.03122,194,329 - 122,206,671 (-)NCBI
Rnor_5.03127,809,688 - 127,822,296 (+)NCBI
RGSC_v3.43117,291,025 - 117,303,367 (-)RGD
Celera3115,716,443 - 115,728,785 (-)RGD
RefSeq Acc Id: XM_017591511   ⟹   XP_017447000
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23116,900,990 - 116,904,600 (-)NCBI
Rnor_6.03122,194,327 - 122,197,725 (-)NCBI
Protein Sequences
Protein RefSeqs NP_062247 (Get FASTA)   NCBI Sequence Viewer  
  XP_017447000 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41118 (Get FASTA)   NCBI Sequence Viewer  
  EDL80169 (Get FASTA)   NCBI Sequence Viewer  
  EDL80170 (Get FASTA)   NCBI Sequence Viewer  
  P06300 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_062247   ⟸   NM_019374
- Peptide Label: preproprotein
- UniProtKB: F1M7S3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447000   ⟸   XM_017591511
- Peptide Label: isoform X1
- UniProtKB: F1M7S3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000038921   ⟸   ENSRNOT00000037576

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06300-F1-model_v2 AlphaFold P06300 1-248 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62054 AgrOrtholog
BioCyc Gene G2FUF-47892 BioCyc
Ensembl Genes ENSRNOG00000026036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000038921 ENTREZGENE
  ENSRNOP00000038921.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037576 ENTREZGENE
  ENSRNOT00000037576.4 UniProtKB/TrEMBL
InterPro Opioid_neupept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proenkphlin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29190 UniProtKB/TrEMBL
PANTHER PTHR11438 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11438:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Opiods_neuropep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pdyn PhenoGen
  PENKBPRCRSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P06300 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q63193 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Pdyn  prodynorphin      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference