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Gene: Pdyn (prodynorphin) Mus musculus
Symbol: Pdyn
Name: prodynorphin
Description: Predicted to have neuropeptide hormone activity and opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Predicted to localize to several cellular components, including axon terminus; neuronal cell body; and secretory vesicle. Is expressed in several structures, including central nervous system and retina. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 23 and temporal lobe epilepsy. Orthologous to human PDYN (prodynorphin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-neoendorphin; beta-neoendorphin; beta-neoendorphin-dynorphin; big dynorphin; Dy; Dyn; dynorphin A(1-13); dynorphin A(1-17); dynorphin A(1-8); leu-enkephalin; leumorphin; preprodynorphin; proenkephalin-B; rimorphin
Homo sapiens (human) : PDYN (prodynorphin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdyn (prodynorphin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdyn (prodynorphin)
Pan paniscus (bonobo/pygmy chimpanzee) : PDYN (prodynorphin)
Canis lupus familiaris (dog) : PDYN (prodynorphin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdyn (prodynorphin)
Sus scrofa (pig) : PDYN (prodynorphin)
Chlorocebus sabaeus (African green monkey) : PDYN (prodynorphin)
Heterocephalus glaber (naked mole-rat) : Pdyn (prodynorphin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2129,686,565 - 129,699,844 (-)EnsemblGRCm38mm10GRCm38
GRCm382129,686,549 - 129,699,938 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372129,513,737 - 129,515,604 (-)NCBIGRCm37mm9NCBIm37
MGSCv362129,378,007 - 129,391,274 (-)NCBImm8
Celera2130,916,433 - 130,918,300 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pdyn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62346
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.