Rab3b (RAB3B, member RAS oncogene family) - Rat Genome Database

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Gene: Rab3b (RAB3B, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab3b
Name: RAB3B, member RAS oncogene family
RGD ID: 620922
Description: Predicted to enable several functions, including GDP binding activity; GTP-dependent protein binding activity; and myosin V binding activity. Predicted to be involved in several processes, including positive regulation of dopamine uptake involved in synaptic transmission; regulation of synaptic vesicle cycle; and regulation of vesicle size. Predicted to act upstream of or within peptidyl-cysteine methylation and regulation of exocytosis. Is active in synaptic vesicle membrane. Orthologous to human RAB3B (RAB3B, member RAS oncogene family); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ras-related protein Rab-3B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,859,034 - 128,926,087 (+)NCBIGRCr8
mRatBN7.25123,629,562 - 123,697,410 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5123,644,423 - 123,697,401 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5126,253,240 - 126,320,296 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,976,344 - 128,043,394 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05128,027,632 - 128,094,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05128,501,789 - 128,568,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,501,847 - 128,568,188 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05132,343,152 - 132,408,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,185,155 - 130,284,038 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15130,229,349 - 130,288,894 (+)NCBI
Celera5122,364,678 - 122,431,394 (+)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Rab3bRat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactionsEXP 64804642,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RAB3B mRNA]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the more ...CTDPMID:19414516
Rab3bRat1,2-dimethylhydrazine decreases expressionISORGD:73658364804641,2-Dimethylhydrazine results in decreased expression of RAB3B mRNACTDPMID:22206623
Rab3bRat1,2-dimethylhydrazine multiple interactionsISORGD:7365836480464Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of RAB3B mRNA]CTDPMID:22206623
Rab3bRat17beta-estradiol multiple interactionsISORGD:7365826480464[Estradiol co-treated with TGFB1 protein] results in increased expression of RAB3B mRNACTDPMID:30165855
Rab3bRat17beta-hydroxy-5alpha-androstan-3-one increases expressionISORGD:7365826480464Dihydrotestosterone results in increased expression of RAB3B mRNACTDPMID:29581250
Rab3bRat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORGD:73658364804642,3',4,4',5-pentachlorobiphenyl results in increased expression of RAB3B mRNACTDPMID:31388691
Rab3bRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:7365836480464Tetrachlorodibenzodioxin affects the expression of RAB3B mRNACTDPMID:21570461|PMID:26377647
Rab3bRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RAB3B mRNACTDPMID:33387578
Rab3bRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:7365836480464Tetrachlorodibenzodioxin results in increased expression of RAB3B mRNACTDPMID:19933214|PMID:25975270|PMID:26290441
Rab3bRat2-bromohexadecanoic acid multiple interactionsISORGD:73658264804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ...CTDPMID:38195004
Rab3bRat2-hydroxypropanoic acid decreases expressionISORGD:7365826480464Lactic Acid results in decreased expression of RAB3B mRNACTDPMID:30851411
Rab3bRat3',5'-cyclic AMP multiple interactionsEXP 64804642,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RAB3B mRNA]CTDPMID:19414516
Rab3bRat3,3',5-triiodo-L-thyronine increases expressionISORGD:7365826480464Triiodothyronine results in increased expression of RAB3B mRNACTDPMID:15507505
Rab3bRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORGD:7365826480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...CTDPMID:28628672
Rab3bRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of RAB3B mRNACTDPMID:30047161
Rab3bRataflatoxin B1 affects expressionISORGD:7365826480464Aflatoxin B1 affects the expression of RAB3B proteinCTDPMID:20106945
Rab3bRatall-trans-retinoic acid increases expressionISORGD:7365826480464Tretinoin results in increased expression of RAB3B mRNACTDPMID:23724009
Rab3bRatalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of RAB3B mRNACTDPMID:35163327
Rab3bRatamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of RAB3B mRNACTDPMID:30047161
Rab3bRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RAB3B mRNACTDPMID:16483693

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Biological Process
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Object Symbol
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Original Reference(s)
Rab3bRatantigen processing and presentation involved_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatantigen processing and presentation involved_inISORGD:7365821624291 PMID:19717423RGDPMID:19717423
Rab3bRatexocytosis involved_inIBACGD:CAL0000186445|MGI:97843|PANTHER:PTN004664821|PomBase:SPAC9E9.07c|RGD:3528|SGD:S000001889|UniProtKB:P20336|UniProtKB:P61006|UniProtKB:P61026|WB:WBGene00004273|dictyBase:DDB_G02800431600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatpeptidyl-cysteine methylation acts_upstream_of_or_withinISORGD:7365831624291 PMID:11121396RGDPMID:11121396
Rab3bRatpositive regulation of dopamine uptake involved in synaptic transmission involved_inISORGD:7365821624291 PMID:20007772RGDPMID:20007772
Rab3bRatpositive regulation of dopamine uptake involved in synaptic transmission involved_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatregulation of exocytosis  TAS 729749 RGD 
Rab3bRatregulation of exocytosis acts_upstream_of_or_withinIEAUniProtKB:Q9CZT8|ensembl:ENSMUSP000001022611600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatregulation of exocytosis acts_upstream_of_or_withinISORGD:7365831624291 PMID:12167638RGDPMID:12167638
Rab3bRatregulation of synaptic vesicle cycle involved_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatregulation of synaptic vesicle cycle involved_inISORGD:7365821624291 PMID:20007772RGDPMID:20007772
Rab3bRatregulation of vesicle size involved_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatregulation of vesicle size involved_inISORGD:7365821624291 PMID:20007772RGDPMID:20007772
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Cellular Component
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Original Reference(s)
Rab3bRatcytoplasm located_inISORGD:7365821624291 PMID:20807725RGDPMID:20807725
Rab3bRatcytoplasm located_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatdopaminergic synapse is_active_inISORGD:7365821624291 PMID:20007772RGDPMID:20007772
Rab3bRatdopaminergic synapse is_active_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatendomembrane system located_inIEAARBA:ARBA000289531600115GO_REF:0000117UniProtGO_REF:0000117
Rab3bRatendosome is_active_inIBAFB:FBgn0262518|MGI:894284|MGI:96960|MGI:97843|PANTHER:PTN000635134|UniProtKB:F1PTE3|UniProtKB:P51153|UniProtKB:P61006|UniProtKB:Q92930|WB:WBGene000042721600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Rab3bRatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Rab3bRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatperinuclear region of cytoplasm located_inIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatperinuclear region of cytoplasm located_inISORGD:7365821624291 PMID:19717423RGDPMID:19717423
Rab3bRatplasma membrane is_active_inIBACGD:CAL0000186445|FB:FBgn0262518|MGI:96960|PANTHER:PTN000635134|UniProtKB:F1PTE3|UniProtKB:P51153|WB:WBGene000042721600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Rab3bRatsecretory granule located_inISORGD:7365831624291 PMID:16043482RGDPMID:16043482
Rab3bRatsecretory granule located_inIEAUniProtKB:Q9CZT8|ensembl:ENSMUSP000001022611600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatsecretory vesicle located_inIEAARBA:ARBA000266251600115GO_REF:0000117UniProtGO_REF:0000117
Rab3bRatsynaptic vesicle is_active_inIBAMGI:1914545|MGI:1917158|MGI:97843|PANTHER:PTN001530779|RGD:3528|RGD:620922|RGD:620923|UniProtKB:P20337|WB:WBGene000042671600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatsynaptic vesicle located_inIEAUniProtKB:Q9CZT8|ensembl:ENSMUSP000001022611600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Object Symbol
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Original Reference(s)
Rab3bRatGDP binding enablesIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatGDP binding enablesISORGD:7365821624291 PMID:22321395RGDPMID:22321395
Rab3bRatGTP binding  NAS 729749 RGD 
Rab3bRatGTP binding enablesIEAInterPro:IPR001806|InterPro:IPR0052251600115GO_REF:0000002InterProGO_REF:0000002
Rab3bRatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatGTP-dependent protein binding enablesISORGD:7365831624291PR:P35276 PMID:21262767RGDPMID:21262767
Rab3bRatGTP-dependent protein binding enablesIEAUniProtKB:Q9CZT8|ensembl:ENSMUSP000001022611600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
Rab3bRatGTPase activity enablesIEAInterPro:IPR001806|InterPro:IPR0378721600115GO_REF:0000002InterProGO_REF:0000002
Rab3bRatGTPase activity enablesIBACGD:CAL0000186445|FB:FBgn0030391|PANTHER:PTN000635132|PomBase:SPAC9E9.07c|SGD:S000001889|UniProtKB:P20336|UniProtKB:P20337|UniProtKB:P51153|UniProtKB:P61006|UniProtKB:Q96E171600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatGTPase activity enablesIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatGTPase activity enablesISORGD:7365821624291 PMID:24891604RGDPMID:24891604
Rab3bRatmyosin V binding enablesISORGD:7365821624291UniProtKB:Q9Y4I1 PMID:24006491RGDPMID:24006491
Rab3bRatmyosin V binding enablesIBAPANTHER:PTN001178498|UniProtKB:O95716|UniProtKB:P20336|UniProtKB:P20337|UniProtKB:Q96E171600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3bRatmyosin V binding enablesIEAUniProtKB:P20337|ensembl:ENSP000003607181600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3bRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Rab3bRatprotein binding enablesISORGD:7365831624291PR:Q768S4|PR:Q99NE5|PR:Q9EQZ7|UniProtKB:Q768S4 PMID:11598194, PMID:12578829, PMID:15159548RGDPMID:11598194|PMID:12578829|PMID:15159548
Rab3bRatprotein binding enablesISORGD:7365821624291UniProtKB:P47224|UniProtKB:Q15042|UniProtKB:Q9H8Y1 PMID:24891604, PMID:32296183, PMID:33961781RGDPMID:24891604|PMID:32296183|PMID:33961781
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Reference Title
Reference Citation
1. Insulin and okadaic acid induce Rab4 redistribution in adipocytes. Cormont M, etal., J Biol Chem. 1993 Sep 15;268(26):19491-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Differential expression of Rab3 isoforms during differentiation of pancreatic acinar cell line AR42J. Klengel R, etal., Biochem Biophys Res Commun 1997 Jul 30;236(3):719-22.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
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PMID:7508866   PMID:7532276   PMID:8889548   PMID:9252191   PMID:10748113   PMID:11121396   PMID:12167638   PMID:12192047   PMID:12477932   PMID:16043482   PMID:16822953   PMID:19056867  
PMID:19717423   PMID:20007772   PMID:20807725   PMID:21262767   PMID:22321395   PMID:23533145   PMID:24006491   PMID:24891604   PMID:29476059  



Rab3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,859,034 - 128,926,087 (+)NCBIGRCr8
mRatBN7.25123,629,562 - 123,697,410 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5123,644,423 - 123,697,401 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5126,253,240 - 126,320,296 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,976,344 - 128,043,394 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05128,027,632 - 128,094,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05128,501,789 - 128,568,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,501,847 - 128,568,188 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05132,343,152 - 132,408,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,185,155 - 130,284,038 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15130,229,349 - 130,288,894 (+)NCBI
Celera5122,364,678 - 122,431,394 (+)NCBICelera
Cytogenetic Map5q34NCBI
RAB3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38151,907,956 - 51,990,700 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl151,907,956 - 51,990,700 (-)EnsemblGRCh38hg38GRCh38
GRCh37152,373,628 - 52,456,372 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36152,157,420 - 52,228,936 (-)NCBINCBI36Build 36hg18NCBI36
Build 34152,096,857 - 52,168,369NCBI
Celera150,660,966 - 50,743,913 (-)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef150,490,781 - 50,573,849 (-)NCBIHuRef
CHM1_1152,491,166 - 52,573,953 (-)NCBICHM1_1
T2T-CHM13v2.0151,789,104 - 51,872,214 (-)NCBIT2T-CHM13v2.0
Rab3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394108,736,267 - 108,800,521 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4108,736,260 - 108,800,521 (+)EnsemblGRCm39 Ensembl
GRCm384108,879,070 - 108,943,324 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,879,063 - 108,943,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv374108,551,675 - 108,615,929 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364108,377,002 - 108,441,256 (+)NCBIMGSCv36mm8
Celera4107,216,795 - 107,279,795 (+)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.67NCBI
Rab3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554647,117,883 - 7,177,534 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554647,117,908 - 7,177,138 (+)NCBIChiLan1.0ChiLan1.0
RAB3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21174,868,518 - 174,951,571 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,010,062 - 174,093,098 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0151,170,956 - 51,242,828 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1152,655,120 - 52,737,856 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl152,666,713 - 52,723,975 (-)Ensemblpanpan1.1panPan2
RAB3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1159,305,495 - 9,378,003 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl159,319,057 - 9,372,518 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,452,491 - 9,534,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0159,425,030 - 9,507,475 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl159,386,741 - 9,503,119 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1159,235,627 - 9,317,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0159,324,977 - 9,407,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0159,342,565 - 9,424,929 (+)NCBIUU_Cfam_GSD_1.0
Rab3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505866,430,985 - 66,491,578 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365228,924,617 - 8,989,734 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365228,924,724 - 8,985,309 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6160,194,555 - 160,255,632 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16160,194,488 - 160,255,635 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26147,898,185 - 147,958,774 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12080,963,320 - 81,036,058 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2080,963,398 - 81,035,657 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603336,204,690 - 36,280,528 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248591,193,503 - 1,249,972 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248591,184,733 - 1,250,402 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rab3b
334 total Variants

Predicted Target Of
Summary Value
Count of predictions:278
Count of miRNA genes:179
Interacting mature miRNAs:200
Transcripts:ENSRNOT00000010645
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 49 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5119085612128034027Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat

1 to 10 of 49 rows
RH128978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25123,697,183 - 123,697,368 (+)MAPPERmRatBN7.2
Rnor_6.05128,567,944 - 128,568,128NCBIRnor6.0
Rnor_5.05132,408,612 - 132,408,796UniSTSRnor5.0
RGSC_v3.45130,283,815 - 130,283,999UniSTSRGSC3.4
Celera5122,431,171 - 122,431,355UniSTS
RH 3.4 Map5812.5UniSTS
Cytogenetic Map5q35UniSTS
RH136876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25123,697,117 - 123,697,267 (+)MAPPERmRatBN7.2
Rnor_6.05128,567,878 - 128,568,027NCBIRnor6.0
Rnor_5.05132,408,546 - 132,408,695UniSTSRnor5.0
RGSC_v3.45130,283,749 - 130,283,898UniSTSRGSC3.4
Celera5122,431,105 - 122,431,254UniSTS
RH 3.4 Map5812.7UniSTS
Cytogenetic Map5q35UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 61 60 30 24 30 6 187 95 93 45 59 30



Ensembl Acc Id: ENSRNOT00000010645   ⟹   ENSRNOP00000010645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5123,644,423 - 123,697,401 (+)Ensembl
Rnor_6.0 Ensembl5128,501,847 - 128,568,188 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098899   ⟹   ENSRNOP00000078014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5123,644,423 - 123,688,140 (+)Ensembl
RefSeq Acc Id: NM_031091   ⟹   NP_112353
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,859,091 - 128,926,087 (+)NCBI
mRatBN7.25123,630,402 - 123,697,407 (+)NCBI
Rnor_6.05128,501,833 - 128,568,167 (+)NCBI
Rnor_5.05132,343,152 - 132,408,838 (+)NCBI
RGSC_v3.45130,185,155 - 130,284,038 (+)RGD
Celera5122,364,678 - 122,431,394 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238531   ⟹   XP_006238593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,859,034 - 128,926,087 (+)NCBI
mRatBN7.25123,630,351 - 123,697,410 (+)NCBI
Rnor_6.05128,501,789 - 128,568,170 (+)NCBI
Rnor_5.05132,343,152 - 132,408,838 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063288471   ⟹   XP_063144541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,859,078 - 128,926,087 (+)NCBI
RefSeq Acc Id: XM_063288472   ⟹   XP_063144542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,859,093 - 128,926,087 (+)NCBI
1 to 11 of 11 rows
Protein RefSeqs NP_112353 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238593 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144541 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144542 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD53965 (Get FASTA)   NCBI Sequence Viewer  
  AAH60562 (Get FASTA)   NCBI Sequence Viewer  
  CAA74341 (Get FASTA)   NCBI Sequence Viewer  
  EDL90382 (Get FASTA)   NCBI Sequence Viewer  
  EDL90383 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010645
GenBank Protein Q63941 (Get FASTA)   NCBI Sequence Viewer  
1 to 11 of 11 rows
RefSeq Acc Id: NP_112353   ⟸   NM_031091
- UniProtKB: Q63941 (UniProtKB/Swiss-Prot),   A6JYX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238593   ⟸   XM_006238531
- Peptide Label: isoform X1
- UniProtKB: Q6P9W6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010645   ⟸   ENSRNOT00000010645
Ensembl Acc Id: ENSRNOP00000078014   ⟸   ENSRNOT00000098899
RefSeq Acc Id: XP_063144541   ⟸   XM_063288471
- Peptide Label: isoform X1
- UniProtKB: Q6P9W6 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-Q63941-F1-model_v2 AlphaFold Q63941 1-219 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693906
Promoter ID:EPDNEW_R4430
Type:initiation region
Name:Rab3b_1
Description:RAB3B, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05128,501,835 - 128,501,895EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40370 BioCyc
Ensembl Genes ENSRNOG00000008001 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010645 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918181 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Rab3 UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
  Small_GTPase_Rab UniProtKB/Swiss-Prot
KEGG Report rno:81755 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72799 IMAGE-MGC_LOAD
NCBI Gene 81755 ENTREZGENE
PANTHER LD44762P UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Rab3b PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008001 RatGTEx
SMART RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I5Y826_RAT UniProtKB/TrEMBL
  A6JYX0 ENTREZGENE, UniProtKB/TrEMBL
  A6JYX1_RAT UniProtKB/TrEMBL
  Q63941 ENTREZGENE
  Q6P9W6 ENTREZGENE, UniProtKB/TrEMBL
  Q9QYT8_RAT UniProtKB/TrEMBL
  RAB3B_RAT UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Rab3b  RAB3B, member RAS oncogene family    Rab3B protein  Name updated 1299863 APPROVED
2002-08-07 Rab3b  Rab3B protein      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_regulation mRNA expression is induced by dexamethasone in pancreatic acinar cells 729749