Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | multiple interactions | EXP | | 6480464 | 2 more ... | CTD | PMID:19414516 | 1,2-dimethylhydrazine | decreases expression | ISO | Rab3b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of RAB3B mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rab3b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of RAB3B mRNA] | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of RAB3B mRNA | CTD | PMID:30165855 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of RAB3B mRNA | CTD | PMID:29581250 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rab3b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAB3B mRNA | CTD | PMID:21570461 and PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAB3B mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAB3B mRNA | CTD | PMID:19933214 more ... | 2-hydroxypropanoic acid | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of RAB3B mRNA | CTD | PMID:30851411 | 3',5'-cyclic AMP | multiple interactions | EXP | | 6480464 | 2 more ... | CTD | PMID:19414516 | 3,3',5-triiodo-L-thyronine | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Triiodothyronine results in increased expression of RAB3B mRNA | CTD | PMID:15507505 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RAB3B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of RAB3B mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RAB3B mRNA | CTD | PMID:30047161 | aflatoxin B1 | affects expression | ISO | RAB3B (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of RAB3B protein | CTD | PMID:20106945 | all-trans-retinoic acid | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RAB3B mRNA | CTD | PMID:23724009 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of RAB3B mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RAB3B mRNA | CTD | PMID:16483693 | arsenite(3-) | affects expression | ISO | RAB3B (Homo sapiens) | 6480464 | arsenite affects the expression of RAB3B mRNA | CTD | PMID:22959463 | atrazine | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Atrazine results in increased expression of RAB3B mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of RAB3B mRNA | CTD | PMID:20106945 more ... | benzo[a]pyrene | affects methylation | ISO | RAB3B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RAB3B promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RAB3B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RAB3B 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RAB3B mRNA | CTD | PMID:15034205 and PMID:32417428 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | bisphenol A | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RAB3B mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RAB3B protein | CTD | PMID:31675489 | butanal | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of RAB3B mRNA | CTD | PMID:26079696 | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of RAB3B mRNA | CTD | PMID:19167457 | carbon nanotube | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of RAB3B mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RAB3B gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RAB3B mRNA | CTD | PMID:32715474 and PMID:37019170 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of RAB3B mRNA | CTD | PMID:23558232 | cisplatin | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of RAB3B mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | EXP | | 6480464 | trichostatin A inhibits the reaction [Cisplatin results in decreased expression of RAB3B mRNA] | CTD | PMID:23558232 | copper(II) sulfate | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of RAB3B mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RAB3B mRNA | CTD | PMID:20106945 more ... | decabromodiphenyl ether | multiple interactions | EXP | | 6480464 | [Flame Retardants co-treated with pentabromodiphenyl ether co-treated with decabromobiphenyl ether co-treated with hexabromocyclododecane] results in decreased expression of RAB3B mRNA | CTD | PMID:32207525 | dexamethasone | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RAB3B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of RAB3B mRNA | CTD | PMID:28628672 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA | CTD | PMID:18636392 | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | diethylstilbestrol | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of RAB3B mRNA | CTD | PMID:36621641 | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein | CTD | PMID:31199487 and PMID:37690569 | disodium selenite | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of RAB3B mRNA | CTD | PMID:18514395 | dorsomorphin | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB3B mRNA | CTD | PMID:27188386 | doxorubicin | affects response to substance | ISO | RAB3B (Homo sapiens) | 6480464 | RAB3B protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | doxorubicin | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RAB3B mRNA | CTD | PMID:30031762 | ethanol | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Ethanol results in increased expression of RAB3B mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | Rab3b (Mus musculus) | 6480464 | Ethanol affects the splicing of RAB3B mRNA | CTD | PMID:30319688 | fenamidone | decreases expression | ISO | Rab3b (Mus musculus) | 6480464 | fenamidone results in decreased expression of RAB3B mRNA | CTD | PMID:27029645 | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of RAB3B mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | ISO | Rab3b (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of RAB3B mRNA] | CTD | PMID:22206623 | geldanamycin | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | geldanamycin results in increased expression of RAB3B mRNA | CTD | PMID:26705709 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RAB3B mRNA | CTD | PMID:22061828 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RAB3B mRNA | CTD | PMID:33387578 | hydroquinone | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | hydroquinone results in increased expression of RAB3B mRNA | CTD | PMID:31256213 | indometacin | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RAB3B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of RAB3B mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RAB3B protein | CTD | PMID:32959892 | ketoconazole | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Ketoconazole results in increased expression of RAB3B mRNA | CTD | PMID:36621641 | L-ascorbic acid | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of RAB3B mRNA | CTD | PMID:17639512 | L-ascorbic acid | increases expression | EXP | | 6480464 | Ascorbic Acid results in increased expression of RAB3B mRNA | CTD | PMID:15372504 | lead(0) | affects expression | ISO | RAB3B (Homo sapiens) | 6480464 | Lead affects the expression of RAB3B mRNA | CTD | PMID:28903495 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of RAB3B mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of RAB3B mRNA | CTD | PMID:26272509 and PMID:28001369 | nickel atom | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Nickel results in decreased expression of RAB3B mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA | CTD | PMID:18636392 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RAB3B mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RAB3B mRNA | CTD | PMID:32680482 | pentanal | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | pentanal results in increased expression of RAB3B mRNA | CTD | PMID:26079696 | perfluorohexanesulfonic acid | decreases expression | ISO | Rab3b (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of RAB3B mRNA | CTD | PMID:37995155 | phenylephrine | decreases expression | EXP | | 6480464 | Phenylephrine results in decreased expression of RAB3B mRNA | CTD | PMID:18158353 | pirinixic acid | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RAB3B mRNA | CTD | PMID:19710929 | progesterone | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Progesterone results in decreased expression of RAB3B mRNA | CTD | PMID:20864642 | propanal | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of RAB3B mRNA | CTD | PMID:26079696 | quercetin | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of RAB3B mRNA | CTD | PMID:17639512 | quercetin | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Quercetin results in increased expression of RAB3B mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of RAB3B mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB3B mRNA | CTD | PMID:27188386 | Se-methyl-L-selenocysteine | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | selenomethylselenocysteine results in increased expression of RAB3B mRNA | CTD | PMID:18514395 | Se-methylselenocysteine | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | selenomethylselenocysteine results in increased expression of RAB3B mRNA | CTD | PMID:18514395 | silicon dioxide | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of RAB3B mRNA and Silicon Dioxide results in increased expression of RAB3B mRNA | CTD | PMID:25351596 and PMID:25895662 | sodium fluoride | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of RAB3B protein | CTD | PMID:27548804 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of RAB3B mRNA | CTD | PMID:30047161 | temozolomide | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of RAB3B mRNA | CTD | PMID:31758290 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of RAB3B mRNA | CTD | PMID:16239168 | thapsigargin | decreases expression | EXP | | 6480464 | Thapsigargin results in decreased expression of RAB3B protein | CTD | PMID:35544339 | thimerosal | affects expression | ISO | RAB3B (Homo sapiens) | 6480464 | Thimerosal affects the expression of RAB3B mRNA | CTD | PMID:27188386 | torcetrapib | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | torcetrapib results in increased expression of RAB3B mRNA | CTD | PMID:23228038 | triadimefon | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | triadimefon results in decreased expression of RAB3B mRNA | CTD | PMID:26705709 | tributylstannane | increases expression | EXP | | 6480464 | tributyltin results in increased expression of RAB3B mRNA | CTD | PMID:21683754 | trichostatin A | multiple interactions | EXP | | 6480464 | trichostatin A inhibits the reaction [Cisplatin results in decreased expression of RAB3B mRNA] | CTD | PMID:23558232 | trichostatin A | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB3B mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RAB3B mRNA | CTD | PMID:26272509 | trichostatin A | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of RAB3B mRNA | CTD | PMID:26705709 | urethane | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Urethane results in increased expression of RAB3B mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Rab3b (Mus musculus) | 6480464 | Valproic Acid affects the expression of RAB3B mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | RAB3B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RAB3B mRNA | CTD | PMID:19101580 more ... | valproic acid | affects expression | ISO | RAB3B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RAB3B mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | Rab3b (Mus musculus) | 6480464 | Valproic Acid results in increased expression of RAB3B mRNA | CTD | PMID:21427059 | vorinostat | decreases expression | ISO | RAB3B (Homo sapiens) | 6480464 | vorinostat results in decreased expression of RAB3B mRNA | CTD | PMID:27188386 | zidovudine | multiple interactions | ISO | RAB3B (Homo sapiens) | 6480464 | [Zidovudine co-treated with IFNA1 protein] results in decreased expression of RAB3B mRNA | CTD | PMID:20370541 | |