Gene: Hibadh (3-hydroxyisobutyrate dehydrogenase) Rattus norvegicus
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Symbol: Hibadh
Name: 3-hydroxyisobutyrate dehydrogenase
Description: ENCODES a protein that exhibits 3-hydroxyisobutyrate dehydrogenase activity (ortholog); INVOLVED IN valine catabolic process (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,4-dinitrotoluene
AGR Description: Predicted to have 3-hydroxyisobutyrate dehydrogenase activity; predicted to be involved in valine catabolic process; predicted to localize to the mitochondrion; orthologous to human HIBADH (3-hydroxyisobutyrate dehydrogenase).
Merged Description: Predicted to have 3-hydroxyisobutyrate dehydrogenase activity; predicted to be involved in valine catabolic process; predicted to localize to the mitochondrion; orthologous to human HIBADH (3-hydroxyisobutyrate dehydrogenase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-hydroxyisobutyrate dehydrogenase, mitochondrial
Orthologs:
Homo sapiens (human) : HIBADH (3-hydroxyisobutyrate dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Hibadh (3-hydroxyisobutyrate dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hibadh (3-hydroxyisobutyrate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HIBADH (3-hydroxyisobutyrate dehydrogenase)
Canis lupus familiaris (dog) : HIBADH (3-hydroxyisobutyrate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hibadh (3-hydroxyisobutyrate dehydrogenase)
Sus scrofa (pig) : HIBADH (3-hydroxyisobutyrate dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0482,604,369 - 82,702,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04147,270,733 - 147,368,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,850,300 - 80,948,361 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1481,134,949 - 81,232,983 (-)NCBI
Celera476,531,774 - 76,629,846 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hibadh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708399
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.