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ONTOLOGY REPORT - ANNOTATIONS


Term:arasertaconazole
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Accession:CHEBI:83685 term browser browse the term
Definition:A 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole that is the active R-enantiomer of sertaconazole and is used (as its nitrate salt) for treatment of vulvovaginal candidiasis. The racemate itself is also used as a broad-spectrum antifungal drug.
Synonyms:exact_synonym: 1-[(2R)-2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
 related_synonym: (R)-sertaconazole;   Formula=C20H15Cl3N2OS;   InChI=1S/C20H15Cl3N2OS/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22/h1-8,11-12,19H,9-10H2/t19-/m0/s1;   InChIKey=JLGKQTAYUIMGRK-IBGZPJMESA-N;   SMILES=Clc1ccc([C@H](Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1;   arasertaconazol;   arasertaconazolum
 xref: CAS:583057-48-1 "ChemIDplus";   Patent:EP2436374;   Patent:WO2012041966;   Reaxys:11333066 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:83699;   is_enantiomer_of CHEBI:83684


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sertaconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        anti-inflammatory agent 14919
          anti-inflammatory drug 13601
            non-steroidal anti-inflammatory drug 12683
              arasertaconazole 1
                sertaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                organic heterocyclic compound 18170
                                  heteroarene 15165
                                    monocyclic heteroarene 11620
                                      azole 10477
                                        diazole 8044
                                          imidazoles 7594
                                            imidazole antifungal agent 1231
                                              imidazole antifungal drug 763
                                                arasertaconazole 1
                                                  sertaconazole 1
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