Ppil1 (peptidylprolyl isomerase like 1) - Rat Genome Database

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Gene: Ppil1 (peptidylprolyl isomerase like 1) Rattus norvegicus
Analyze
Symbol: Ppil1
Name: peptidylprolyl isomerase like 1
RGD ID: 1309119
Description: Predicted to enable cyclosporin A binding activity; disordered domain specific binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in embryonic brain development; mRNA splicing, via spliceosome; and protein peptidyl-prolyl isomerization. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 14. Orthologous to human PPIL1 (peptidylprolyl isomerase like 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC309651; MGC116359; peptidyl-prolyl cis-trans isomerase-like 1; peptidylprolyl isomerase (cyclophilin)-like 1; peptidylprolyl isomerase-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2207,302,292 - 7,322,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,302,621 - 7,322,354 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,013,297 - 8,028,144 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0207,375,155 - 7,390,002 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0207,850,087 - 7,864,954 (-)NCBIRnor_WKY
Rnor_6.0206,515,638 - 6,864,571 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,515,638 - 6,864,571 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,102,772 - 9,104,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0208,760,182 - 8,761,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,548,896 - 7,565,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,549,743 - 7,565,928 (-)NCBI
Celera208,852,048 - 8,866,821 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Splicing and beyond: the many faces of the Prp19 complex. Chanarat S and Strasser K, Biochim Biophys Acta. 2013 Oct;1833(10):2126-34. doi: 10.1016/j.bbamcr.2013.05.023. Epub 2013 Jun 3.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Spliceosomal immunophilins. Mesa A, etal., FEBS Lett. 2008 Jul 9;582(16):2345-51. doi: 10.1016/j.febslet.2008.06.006. Epub 2008 Jun 9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11991638   PMID:12477932   PMID:16595688   PMID:20007319   PMID:20676357   PMID:23376485   PMID:28076346  


Genomics

Comparative Map Data
Ppil1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2207,302,292 - 7,322,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,302,621 - 7,322,354 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,013,297 - 8,028,144 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0207,375,155 - 7,390,002 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0207,850,087 - 7,864,954 (-)NCBIRnor_WKY
Rnor_6.0206,515,638 - 6,864,571 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,515,638 - 6,864,571 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,102,772 - 9,104,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0208,760,182 - 8,761,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,548,896 - 7,565,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,549,743 - 7,565,928 (-)NCBI
Celera208,852,048 - 8,866,821 (-)NCBICelera
Cytogenetic Map20p12NCBI
PPIL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,854,829 - 36,874,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl636,854,827 - 36,874,803 (-)EnsemblGRCh38hg38GRCh38
GRCh37636,822,605 - 36,842,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,930,583 - 36,950,747 (-)NCBINCBI36Build 36hg18NCBI36
Build 34636,930,585 - 36,950,747NCBI
Celera638,377,637 - 38,397,836 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef636,540,910 - 36,561,109 (-)NCBIHuRef
CHM1_1636,824,537 - 36,844,718 (-)NCBICHM1_1
T2T-CHM13v2.0636,675,439 - 36,695,414 (-)NCBIT2T-CHM13v2.0
Ppil1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,469,809 - 29,482,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,469,777 - 29,483,160 (-)EnsemblGRCm39 Ensembl
GRCm381729,250,835 - 29,263,971 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,250,803 - 29,264,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv371729,387,780 - 29,400,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,977,847 - 28,990,983 (-)NCBIMGSCv36mm8
Celera1729,800,905 - 29,814,390 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
Ppil1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,131,013 - 6,143,529 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,131,013 - 6,143,474 (+)NCBIChiLan1.0ChiLan1.0
PPIL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1637,612,722 - 37,632,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl637,612,724 - 37,632,942 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0636,417,086 - 36,437,259 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PPIL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,916,524 - 5,936,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,917,228 - 5,942,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,265,627 - 6,290,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBIUU_Cfam_GSD_1.0
Ppil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,389,370 - 41,407,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647622,552,566 - 22,571,001 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647622,552,484 - 22,570,860 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,522,733 - 32,547,839 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1732,522,736 - 32,547,874 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,426,210 - 37,451,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPIL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,260,471 - 35,281,367 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604436,798,831 - 36,819,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppil1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475420,976,515 - 20,985,393 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475420,976,765 - 20,985,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppil1
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:50
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000068527
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat

Markers in Region
203J18-Sp6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2207,303,689 - 7,303,848 (+)MAPPERmRatBN7.2
Rnor_6.0206,517,033 - 6,517,191NCBIRnor6.0
Rnor_5.0208,761,577 - 8,761,735UniSTSRnor5.0
RGSC_v3.4207,550,291 - 7,550,449UniSTSRGSC3.4
Celera208,853,443 - 8,853,601UniSTS
Cytogenetic Map20p12UniSTS
RH127896  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2207,317,958 - 7,318,140 (+)MAPPERmRatBN7.2
Rnor_6.0206,865,375 - 6,865,556NCBIRnor6.0
Rnor_5.0209,105,410 - 9,105,591UniSTSRnor5.0
RGSC_v3.4207,566,442 - 7,566,623UniSTSRGSC3.4
Celera208,867,623 - 8,867,804UniSTS
RH 3.4 Map2077.5UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 47 31 19 31 1 2 74 35 41 11 1
Low 7 10 10 10 7 9 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000068527   ⟹   ENSRNOP00000061533
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl206,516,264 - 6,864,387 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093253   ⟹   ENSRNOP00000076232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl207,302,621 - 7,322,354 (-)Ensembl
Rnor_6.0 Ensembl206,515,638 - 6,864,571 (-)Ensembl
RefSeq Acc Id: NM_001034188   ⟹   NP_001029360
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2207,302,295 - 7,317,157 (-)NCBI
Rnor_6.0206,515,638 - 6,864,571 (-)NCBI
Rnor_5.0208,760,182 - 8,761,633 (-)NCBI
Rnor_5.0209,102,772 - 9,104,606 (-)NCBI
RGSC_v3.4207,548,896 - 7,565,640 (-)RGD
Celera208,852,048 - 8,866,821 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098710   ⟹   XP_038954638
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2207,302,292 - 7,322,349 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001029360 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954638 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99188 (Get FASTA)   NCBI Sequence Viewer  
  EDL96958 (Get FASTA)   NCBI Sequence Viewer  
  EDL96959 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001029360   ⟸   NM_001034188
- UniProtKB: Q4KLI4 (UniProtKB/TrEMBL),   F7FJ93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061533   ⟸   ENSRNOT00000068527
RefSeq Acc Id: ENSRNOP00000076232   ⟸   ENSRNOT00000093253
RefSeq Acc Id: XP_038954638   ⟸   XM_039098710
- Peptide Label: isoform X1
- UniProtKB: F7FJ93 (UniProtKB/TrEMBL)
Protein Domains
PPIase cyclophilin-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLI4-F1-model_v2 AlphaFold Q4KLI4 1-166 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701443
Promoter ID:EPDNEW_R11965
Type:multiple initiation site
Name:Ppil1_1
Description:peptidylprolyl isomerase like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0206,864,418 - 6,864,478EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309119 AgrOrtholog
BioCyc Gene G2FUF-4385 BioCyc
Ensembl Genes ENSRNOG00000000523 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000076232 ENTREZGENE
  ENSRNOP00000076232.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000093253 ENTREZGENE
  ENSRNOT00000093253.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7383385 IMAGE-MGC_LOAD
InterPro Cyclophilin-like_dom UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin_A-like UniProtKB/TrEMBL
  Pep-Pro_Isoase_cyclophilin_CS UniProtKB/TrEMBL
  PPIase_cyclophilin UniProtKB/TrEMBL
KEGG Report rno:309651 UniProtKB/TrEMBL
MGC_CLONE MGC:116359 IMAGE-MGC_LOAD
NCBI Gene 309651 ENTREZGENE
PANTHER PTHR45625 UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PhenoGen Ppil1 PhenoGen
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt F7FJ93 ENTREZGENE
  Q4KLI4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7FJ93 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Ppil1  peptidylprolyl isomerase like 1  Ppil1  peptidylprolyl isomerase (cyclophilin)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ppil1  peptidylprolyl isomerase (cyclophilin)-like 1  Ppil1_predicted  peptidylprolyl isomerase (cyclophilin)-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ppil1_predicted  peptidylprolyl isomerase (cyclophilin)-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED