Micb (MHC class I polypeptide-related sequence B)

Advanced Search (OLGA)

Gene: Micb (MHC class I polypeptide-related sequence B) Rattus norvegicus

Analyze

Symbol:

Micb

Name:

MHC class I polypeptide-related sequence B

RGD ID:

1564508

Description:

Predicted to enable natural killer cell lectin-like receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; positive regulation of immune response; and response to retinoic acid. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MICA (MHC class I polypeptide-related sequence A) and MICB (MHC class I polypeptide-related sequence B); INTERACTS WITH acrylamide; bisphenol A; glycidol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MHC class I-like located near the leukocyte receptor complex 2; MHC class I-like located near the LRC, 2; MHC class I-like protein MILL2; MHC I like leukocyte 2; Mill2; Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

NCBI Annotation Information:

Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	87,623,826 - 87,641,075 (+)	NCBI		GRCr8
mRatBN7.2	1	78,495,779 - 78,513,030 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	78,495,779 - 78,512,827 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	83,884,920 - 83,902,263 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,441,736 - 92,459,267 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	85,640,035 - 85,657,377 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,754,587 - 79,772,092 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,754,587 - 79,772,092 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	81,016,678 - 81,033,651 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,199,668 - 78,216,687 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	72,962,833 - 72,979,882 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dengue hemorrhagic fever (ISO)

megacolon (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

8-Br-cAMP (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

erlotinib hydrochloride (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gefitinib (ISO)

glycidol (EXP)

ketoconazole (ISO)

L-methionine (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

paclitaxel (ISO)

panobinostat (ISO)

paracetamol (ISO)

pentanal (ISO)

propanal (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

temozolomide (ISO)

thapsigargin (ISO)

thiram (ISO)

triadimefon (ISO)

tributylstannane (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (IBA)

antigen processing and presentation of endogenous peptide antigen via MHC class Ib (IBA)

gamma-delta T cell activation (ISO)

immune response (IBA)

immune response-activating cell surface receptor signaling pathway (ISO)

positive regulation of T cell mediated cytotoxicity (IBA)

response to heat (ISO)

response to oxidative stress (ISO)

response to retinoic acid (ISO)

Cellular Component

external side of plasma membrane (IBA,ISO)

extracellular space (IBA)

Molecular Function

natural killer cell lectin-like receptor binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9497295	PMID:11239445	PMID:11287116	PMID:11491531	PMID:12569559	PMID:12782710	PMID:15162429

Genomics

Comparative Map Data

Micb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	87,623,826 - 87,641,075 (+)	NCBI		GRCr8
mRatBN7.2	1	78,495,779 - 78,513,030 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	78,495,779 - 78,512,827 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	83,884,920 - 83,902,263 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,441,736 - 92,459,267 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	85,640,035 - 85,657,377 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,754,587 - 79,772,092 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,754,587 - 79,772,092 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	81,016,678 - 81,033,651 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,199,668 - 78,216,687 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	72,962,833 - 72,979,882 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

MICB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,494,918 - 31,511,124 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,494,881 - 31,511,124 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,462,695 - 31,478,901 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,573,945 - 31,586,880 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,573,944 - 31,586,879	NCBI
Celera	6	33,071,633 - 33,077,144 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,252,690 - 31,265,723 (+)	NCBI		HuRef
CHM1_1	6	31,468,019 - 31,481,042 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,345,743 - 31,364,224 (+)	NCBI		T2T-CHM13v2.0

Mill2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	18,573,878 - 18,603,621 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	18,573,891 - 18,599,327 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	18,839,958 - 18,869,696 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	18,839,966 - 18,865,402 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	19,425,315 - 19,444,002 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	17,998,488 - 18,021,211 (+)	NCBI		MGSCv36	mm8
Celera	7	16,239,887 - 16,258,480 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.35	NCBI

MICB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	45,966,186 - 45,983,414 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	41,929,429 - 41,944,967 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,151,935 - 31,167,567 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,042,011 - 32,057,761 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

MICB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,518,365 - 40,532,637 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666044	31,347,368 - 31,422,297 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Micb
163 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53895117	82174945	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49361465	82174945	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	34836858	79836858	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53895117	82174945	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	78430754	91209302	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	90	89	58	25	58	6	217	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001017468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_190833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB113963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB114035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC093995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC110846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CM042093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000083211 ⟹ ENSRNOP00000074366

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	78,495,779 - 78,512,827 (+)	Ensembl
Rnor_6.0 Ensembl	1	79,754,587 - 79,772,092 (+)	Ensembl

RefSeq Acc Id:

NM_001017468 ⟹ NP_001017468

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	87,623,826 - 87,641,075 (+)	NCBI
mRatBN7.2	1	78,495,779 - 78,513,030 (+)	NCBI
Rnor_6.0	1	79,754,587 - 79,772,092 (+)	NCBI
Rnor_5.0	1	81,016,678 - 81,033,651 (+)	NCBI
RGSC_v3.4	1	78,199,668 - 78,216,687 (+)	RGD
Celera	1	72,962,833 - 72,979,882 (+)	RGD

Sequence:

show sequence

AAGTATGTGCCCACACAAAGGAGGAAAATGGAAGCCAGTTCTGGAACAGCAGGACCAGCAGTCC
TACTGTTGATCTTAGCGCTGCTCCTGACAGAGTCACAGGGATCCAGGAGCCAGGGAACCCACAC
TCTGCGCTATGATGTCACAGCCTGTTTTCTGGAGGGCTCTGAGCAGACCAGGCTCCTGGTCCTA
ATATACGTAGACGATGAGCTCTTCCTGAGGTACAATGGAGACAGGAGGAGTGCAAAGCCCTGGG
CATGCTGGATTAAGGGCCATGGGGGAGATGAGACGTGTGCAAGAGAGGTTGAGAATCTGCCGAA
GGAGGAGGAGAGACTCAGGGAGATGATGGCTGAGATGATAAACCAGAAGGGCCACGACAAAGGC
CCATACACTCTTCAGGCAACCCTGGGCTGTGAGCTTCAAAGAAACGGAAGCACTAGAGGCTTCT
GGCACCTGGGCTACGAAGGGCGGAACCTCCTCACCTTCGACCAGAAGACTCTCACATGGACAAT
GGATGTGCCCTTCACCCAGCAGAAGAAGACGTTCTGGGAGCCACGTGCACCCAAAGCTGACCTA
GTTAAGACGTTCTTGGATGAGACATGTCCTGCTCGGCTCCAGAGACACCTGGCTTCCTTGAGTA
ATGTTCTGCCGGATACAGGTTCCCCAGTGGTGATTGTGACCTGCAGGAATTATCCCGTGGGCAG
GATCACGCTGACATGCCGGGCTTTTAATCTGAGTTCCCATGTGGCCACCCTGCTCTGGCTTCGG
GACGGGAAGCCGGTACAGCAGGATGTCTTTGGGCCTGGGACCATCCTGCCCAGTGGGGACGGGA
CCTACCAGACCTGGGTGTCCATTCGGGTTCTTCCTGGACAGGAACCACAGTTCGCCTGCAACCT
GAGGCATAGCAACCGCACCATCATGCAGACCGCTGTCTCTGGCGAGAGCATGGGATGGCCATCC
GCCTCATGGGCTACGAGGCAAGAGGCGGAAGGACCCCATAGGACACACAATGACCACGTGGTTG
ATGGCGGACTGGTTACGGGGAATGCTAATAAGGACAGTCCAGATGCTTCCAGCTGTGCTACAGC
CTCAGCCATATCTGCGTTCCCCGTTGTCGTGTTGTCTGTGGCACTGCCCAGAGCCAACTGAATC
CAGAGCCCAAAGGATAAGAAGCTTCCAGTTAGGAGGGACAGGACGTGAGT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001017468	(Get FASTA)	NCBI Sequence Viewer
	NP_001416892	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A0A0G2K7V7	(Get FASTA)	NCBI Sequence Viewer
	BAD54799	(Get FASTA)	NCBI Sequence Viewer
	BAD54800	(Get FASTA)	NCBI Sequence Viewer
	BAD54801	(Get FASTA)	NCBI Sequence Viewer
	BAD54802	(Get FASTA)	NCBI Sequence Viewer
	BAD54803	(Get FASTA)	NCBI Sequence Viewer
	BAD54804	(Get FASTA)	NCBI Sequence Viewer
	BAD54805	(Get FASTA)	NCBI Sequence Viewer
	BAD54806	(Get FASTA)	NCBI Sequence Viewer
	BAD54807	(Get FASTA)	NCBI Sequence Viewer
	BAD54808	(Get FASTA)	NCBI Sequence Viewer
	BAD54809	(Get FASTA)	NCBI Sequence Viewer
	BAD54810	(Get FASTA)	NCBI Sequence Viewer
	BAD54811	(Get FASTA)	NCBI Sequence Viewer
	BAD54812	(Get FASTA)	NCBI Sequence Viewer
	BAD54813	(Get FASTA)	NCBI Sequence Viewer
	BAD54814	(Get FASTA)	NCBI Sequence Viewer
	BAD54815	(Get FASTA)	NCBI Sequence Viewer
	BAD54816	(Get FASTA)	NCBI Sequence Viewer
	BAD54817	(Get FASTA)	NCBI Sequence Viewer
	BAD54818	(Get FASTA)	NCBI Sequence Viewer
	BAD54819	(Get FASTA)	NCBI Sequence Viewer
	BAD54820	(Get FASTA)	NCBI Sequence Viewer
	BAD54821	(Get FASTA)	NCBI Sequence Viewer
	BAD54822	(Get FASTA)	NCBI Sequence Viewer
	BAD54823	(Get FASTA)	NCBI Sequence Viewer
	EDM08254	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074366.2

RefSeq Acc Id:

NP_001017468 ⟸ NM_001017468

- Peptide Label:

precursor

- Sequence:

show sequence

MEASSGTAGPAVLLLILALLLTESQGSRSQGTHTLRYDVTACFLEGSEQTRLLVLIYVDDELFL
RYNGDRRSAKPWACWIKGHGGDETCAREVENLPKEEERLREMMAEMINQKGHDKGPYTLQATLG
CELQRNGSTRGFWHLGYEGRNLLTFDQKTLTWTMDVPFTQQKKTFWEPRAPKADLVKTFLDETC
PARLQRHLASLSNVLPDTGSPVVIVTCRNYPVGRITLTCRAFNLSSHVATLLWLRDGKPVQQDV
FGPGTILPSGDGTYQTWVSIRVLPGQEPQFACNLRHSNRTIMQTAVSGESMGWPSASWATRQEA
EGPHRTHNDHVVDGGLVTGNANKDSPDASSCATASAISAFPVVVLSVALPRAN

hide sequence

Ensembl Acc Id:

ENSRNOP00000074366 ⟸ ENSRNOT00000083211

Protein Domains

Ig-like Ig-like C1-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K7V7-F1-model_v2	AlphaFold	A0A0G2K7V7	1-372	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689750

Promoter ID:

EPDNEW_R274

Type:

single initiation site

Name:

Micb_1

Description:

MHC class I polypeptide-related sequence B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	79,754,588 - 79,754,648	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564508	AgrOrtholog
BioCyc Gene	G2FUF-60552	BioCyc
Ensembl Genes	ENSRNOG00000057645	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000083211.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.500.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_C1-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_class-I_related	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I-like_Ag-recog	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I-like_Ag-recog_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I/II-like_Ag-recog	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:365212	UniProtKB/Swiss-Prot
NCBI Gene	365212	ENTREZGENE
PANTHER	MHC CLASS I-LIKE PROTEIN MILL2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC CLASS I-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	C1-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Micb	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000057645	RatGTEx
SMART	IGc1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54452	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K7V7	ENTREZGENE
	A0A8L2R8P8_RAT	UniProtKB/TrEMBL
	MILL2_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q60I19	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-02-18	Micb	MHC class I polypeptide-related sequence B	Mill2	MHC I like leukocyte 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	Mill2	MHC I like leukocyte 2	Mill2	Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	Mill2	Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD