Mbnl2 (muscleblind-like splicing regulator 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Mbnl2 (muscleblind-like splicing regulator 2) Rattus norvegicus
Analyze
Symbol: Mbnl2
Name: muscleblind-like splicing regulator 2
RGD ID: 1591755
Description: Predicted to enable RNA binding activity and sequence-specific double-stranded DNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human MBNL2 (muscleblind like splicing regulator 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC680445; muscleblind-like 2; muscleblind-like protein 2; similar to muscleblind-like 2 isoform 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815103,792,134 - 103,949,827 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl15103,792,152 - 103,949,827 (+)EnsemblGRCr8
mRatBN7.21597,385,278 - 97,542,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1597,385,244 - 97,542,937 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx15101,311,923 - 101,471,980 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015102,414,054 - 102,574,110 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01599,354,320 - 99,514,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.015105,640,097 - 105,797,933 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15105,640,097 - 105,797,932 (+)Ensemblrn6Rnor6.0
Rnor_5.015109,043,305 - 109,200,834 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.415105,356,456 - 105,514,135 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1596,204,034 - 96,361,422 (+)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
captan  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
clorgyline  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
Mesaconitine  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
miconazole  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
nickel dichloride  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rimonabant  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
nucleoplasm  (IBA,IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers. Nakagaki-Silva EE, etal., Elife. 2019 Jul 8;8:e46327. doi: 10.7554/eLife.46327.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:15257297   PMID:16946708   PMID:19457059   PMID:19720736   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Mbnl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815103,792,134 - 103,949,827 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl15103,792,152 - 103,949,827 (+)EnsemblGRCr8
mRatBN7.21597,385,278 - 97,542,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1597,385,244 - 97,542,937 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx15101,311,923 - 101,471,980 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015102,414,054 - 102,574,110 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01599,354,320 - 99,514,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.015105,640,097 - 105,797,933 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15105,640,097 - 105,797,932 (+)Ensemblrn6Rnor6.0
Rnor_5.015109,043,305 - 109,200,834 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.415105,356,456 - 105,514,135 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1596,204,034 - 96,361,422 (+)NCBICelera
Cytogenetic Map15q24NCBI
MBNL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381397,141,834 - 97,394,120 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1397,221,434 - 97,394,120 (+)Ensemblhg38GRCh38
GRCh371397,794,088 - 98,046,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361396,672,575 - 96,844,375 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1378,721,989 - 78,893,793 (+)NCBICelera
Cytogenetic Map13q32.1NCBI
HuRef1378,471,234 - 78,643,205 (+)NCBIHuRef
CHM1_11397,844,925 - 98,016,876 (+)NCBICHM1_1
T2T-CHM13v2.01396,345,880 - 96,600,426 (+)NCBIT2T-CHM13v2.0
Mbnl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914120,513,077 - 120,669,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14120,513,081 - 120,669,109 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3814120,275,652 - 120,431,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14120,275,669 - 120,431,697 (+)Ensemblmm10GRCm38
MGSCv3714120,674,891 - 120,830,920 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3614119,410,851 - 119,566,877 (+)NCBIMGSCv36mm8
Celera14118,828,759 - 118,986,361 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1464.44NCBI
Mbnl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,979,235 - 13,132,361 (-)Ensembl
ChiLan1.0NW_00495540412,979,671 - 13,132,239 (-)NCBIChiLan1.0ChiLan1.0
MBNL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21498,657,810 - 98,912,156 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11397,326,508 - 97,580,896 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01378,301,339 - 78,555,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11397,538,615 - 97,711,843 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1397,591,686 - 97,711,843 (+)EnsemblpanPan2panpan1.1
MBNL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12247,568,335 - 47,729,901 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2247,619,002 - 47,727,550 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2247,348,675 - 47,510,527 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02247,994,403 - 48,156,428 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2247,994,663 - 48,156,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12247,657,892 - 47,819,727 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02247,691,268 - 47,853,427 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02247,727,618 - 47,889,505 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mbnl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,095,913 - 183,246,351 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647212,705,804 - 12,856,048 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647212,705,804 - 12,856,058 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBNL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1166,481,923 - 66,641,653 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11166,481,923 - 66,641,653 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21173,458,684 - 73,590,555 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MBNL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1375,936,438 - 76,108,163 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl375,987,751 - 76,109,519 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604632,387,044 - 32,558,863 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbnl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248793,768,084 - 3,922,407 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248793,768,073 - 3,921,251 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:129
Interacting mature miRNAs:141
Transcripts:ENSRNOT00000014300
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1582194914108192169Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1574735564106469153Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1588677086104695021Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1582503470108192169Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1582714037106778197Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)1588677086104695021Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
7411646Foco21Food consumption QTL 2123.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1584278281108192169Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1583700787108192169Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1567399137108192169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1582194914108192169Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA818999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI602815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE111982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ202225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB576955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB757029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK603100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN540999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO405101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV108304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000014300   ⟹   ENSRNOP00000014300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,949,827 (+)Ensembl
mRatBN7.2 Ensembl1597,385,244 - 97,542,923 (+)Ensembl
Rnor_6.0 Ensembl15105,640,097 - 105,797,932 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095906   ⟹   ENSRNOP00000089857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,949,827 (+)Ensembl
mRatBN7.2 Ensembl1597,385,244 - 97,542,937 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109835   ⟹   ENSRNOP00000077342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,949,827 (+)Ensembl
mRatBN7.2 Ensembl1597,385,244 - 97,542,923 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116108   ⟹   ENSRNOP00000094173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,949,827 (+)Ensembl
mRatBN7.2 Ensembl1597,385,278 - 97,542,908 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000138409   ⟹   ENSRNOP00000112083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,947,734 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160527   ⟹   ENSRNOP00000112436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,925,275 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166586   ⟹   ENSRNOP00000101419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,188 - 103,941,640 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173246   ⟹   ENSRNOP00000099124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15103,792,152 - 103,947,734 (+)Ensembl
RefSeq Acc Id: NM_001111064   ⟹   NP_001104534
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
Rnor_6.015105,640,097 - 105,797,933 (+)NCBI
Rnor_5.015109,043,305 - 109,200,834 (+)NCBI
RGSC_v3.415105,356,456 - 105,514,135 (+)RGD
Celera1596,204,034 - 96,361,422 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415043   ⟹   NP_001401972
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
RefSeq Acc Id: NM_001415044   ⟹   NP_001401973
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
RefSeq Acc Id: NM_001415045   ⟹   NP_001401974
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
RefSeq Acc Id: NM_001415046   ⟹   NP_001401975
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
RefSeq Acc Id: NM_001415047   ⟹   NP_001401976
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,188 - 103,949,827 (+)NCBI
mRatBN7.21597,385,278 - 97,542,924 (+)NCBI
RefSeq Acc Id: NM_001415048   ⟹   NP_001401977
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,822,824 - 103,949,827 (+)NCBI
mRatBN7.21597,415,915 - 97,542,924 (+)NCBI
RefSeq Acc Id: XM_063274619   ⟹   XP_063130689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,134 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274620   ⟹   XP_063130690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,805,419 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274621   ⟹   XP_063130691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,822,773 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274622   ⟹   XP_063130692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,792,134 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274624   ⟹   XP_063130694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,822,773 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274625   ⟹   XP_063130695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,822,773 - 103,949,827 (+)NCBI
RefSeq Acc Id: XM_063274626   ⟹   XP_063130696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815103,805,265 - 103,949,827 (+)NCBI
RefSeq Acc Id: NP_001104534   ⟸   NM_001111064
- Peptide Label: isoform 1
- UniProtKB: F2Z3T4 (UniProtKB/Swiss-Prot),   A6HUI3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014300   ⟸   ENSRNOT00000014300
Ensembl Acc Id: ENSRNOP00000089857   ⟸   ENSRNOT00000095906
Ensembl Acc Id: ENSRNOP00000077342   ⟸   ENSRNOT00000109835
Ensembl Acc Id: ENSRNOP00000094173   ⟸   ENSRNOT00000116108
RefSeq Acc Id: NP_001401972   ⟸   NM_001415043
- Peptide Label: isoform 2
- UniProtKB: A0A8I5Y5P3 (UniProtKB/TrEMBL),   A6HUI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401973   ⟸   NM_001415044
- Peptide Label: isoform 3
- UniProtKB: A0A8I6AKC8 (UniProtKB/TrEMBL),   A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401974   ⟸   NM_001415045
- Peptide Label: isoform 4
- UniProtKB: A6HUI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401976   ⟸   NM_001415047
- Peptide Label: isoform 6
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401975   ⟸   NM_001415046
- Peptide Label: isoform 5
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401977   ⟸   NM_001415048
- Peptide Label: isoform 6
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130689   ⟸   XM_063274619
- Peptide Label: isoform X1
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130692   ⟸   XM_063274622
- Peptide Label: isoform X2
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130696   ⟸   XM_063274626
- Peptide Label: isoform X5
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130690   ⟸   XM_063274620
- Peptide Label: isoform X1
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130691   ⟸   XM_063274621
- Peptide Label: isoform X1
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130694   ⟸   XM_063274624
- Peptide Label: isoform X3
- UniProtKB: A6HUI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130695   ⟸   XM_063274625
- Peptide Label: isoform X4
- UniProtKB: A6HUI3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000099124   ⟸   ENSRNOT00000173246
Ensembl Acc Id: ENSRNOP00000101419   ⟸   ENSRNOT00000166586
Ensembl Acc Id: ENSRNOP00000112083   ⟸   ENSRNOT00000138409
Ensembl Acc Id: ENSRNOP00000112436   ⟸   ENSRNOT00000160527
Protein Domains
C3H1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F2Z3T4-F1-model_v2 AlphaFold F2Z3T4 1-373 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699877
Promoter ID:EPDNEW_R10400
Type:multiple initiation site
Name:Mbnl2_1
Description:muscleblind-like splicing regulator 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.015105,640,131 - 105,640,191EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591755 AgrOrtholog
BioCyc Gene G2FUF-12401 BioCyc
Ensembl Genes ENSRNOG00000010737 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014300 ENTREZGENE
  ENSRNOT00000014300.8 UniProtKB/Swiss-Prot
  ENSRNOT00000095906 ENTREZGENE
  ENSRNOT00000109835 ENTREZGENE
  ENSRNOT00000116108 ENTREZGENE
  ENSRNOT00000160527 ENTREZGENE
  ENSRNOT00000173246 ENTREZGENE
Gene3D-CATH 3.30.1370.210 UniProtKB/Swiss-Prot
InterPro Znf-CCCH_Muscleblind-like UniProtKB/Swiss-Prot
  Znf_CCCH UniProtKB/Swiss-Prot
KEGG Report rno:680445 UniProtKB/Swiss-Prot
NCBI Gene 680445 ENTREZGENE
PANTHER MUSCLEBLIND-LIKE PROTEIN UniProtKB/Swiss-Prot
  MUSCLEBLIND-LIKE PROTEIN 2 UniProtKB/Swiss-Prot
Pfam zf-CCCH UniProtKB/Swiss-Prot
  zf-CCCH_10 UniProtKB/Swiss-Prot
PhenoGen Mbnl2 PhenoGen
PROSITE ZF_C3H1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010737 RatGTEx
SMART ZnF_C3H1 UniProtKB/Swiss-Prot
UniProt A0A8I5Y5P3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ACI9_RAT UniProtKB/TrEMBL
  A0A8I6AKC8 ENTREZGENE, UniProtKB/TrEMBL
  A6HUI2 ENTREZGENE, UniProtKB/TrEMBL
  A6HUI3 ENTREZGENE, UniProtKB/TrEMBL
  F2Z3T4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Mbnl2  muscleblind-like splicing regulator 2  Mbnl2  muscleblind-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-16 Mbnl2  muscleblind-like 2   LOC680445  similar to muscleblind-like 2 isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC680445  similar to muscleblind-like 2 isoform 1  LOC686892  similar to muscleblind-like 1 isoform d  Data merged from RGD:1592466 1643240 APPROVED
2006-11-20 LOC680445  similar to muscleblind-like 2 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC686892  similar to muscleblind-like 1 isoform d      Symbol and Name status set to provisional 70820 PROVISIONAL