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Gene: Erc1 (ELKS/RAB6-interacting/CAST family member 1) Rattus norvegicus
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Symbol: Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Description: Exhibits PDZ domain binding activity. Predicted to be involved in I-kappaB phosphorylation; retrograde transport, endosome to Golgi; and synaptic vesicle priming. Localizes to the cytoplasm; membrane; and postsynaptic density. Orthologous to human ERC1 (ELKS/RAB6-interacting/CAST family member 1); PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAST; Cast2; CAZ-associated structural protein 2; Elks; ERC; ERC protein 1; ERC-1; ERC1b; Rab6 interacting protein 2; Rab6-interacting protein 2; Rab6ip2; RIM-Binding Protein
Orthologs:
Homo sapiens (human) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)  HGNC  Alliance
Mus musculus (house mouse) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Canis lupus familiaris (dog) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Sus scrofa (pig) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04152,087,393 - 152,380,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04219,174,705 - 219,465,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44155,931,377 - 156,221,104 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14156,234,169 - 156,465,945 (-)NCBI
Celera4141,623,820 - 141,910,539 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Erc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628733
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.