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Gene: Tmem106b (transmembrane protein 106B) Rattus norvegicus
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Symbol: Tmem106b
Name: transmembrane protein 106B
Description: Predicted to be involved in several processes, including generation of neurons; lysosome localization; and lysosome organization. Predicted to localize to the endosome and lysosomal membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LRRGT00101; MGC94135; similar to RIKEN cDNA 2310036D22
Orthologs:
Homo sapiens (human) : TMEM106B (transmembrane protein 106B)  HGNC  Alliance
Mus musculus (house mouse) : Tmem106b (transmembrane protein 106B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmem106b (transmembrane protein 106B)
Pan paniscus (bonobo/pygmy chimpanzee) : TMEM106B (transmembrane protein 106B)
Canis lupus familiaris (dog) : TMEM106B (transmembrane protein 106B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmem106b (transmembrane protein 106B)
Sus scrofa (pig) : TMEM106B (transmembrane protein 106B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0439,517,679 - 39,534,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0439,352,537 - 39,371,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4438,398,245 - 38,415,059 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1438,516,785 - 38,533,599 (-)NCBI
Celera436,699,886 - 36,716,700 (+)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tmem106b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303037
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.