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Gene: Hnrnpa2b1 (heterogeneous nuclear ribonucleoprotein A2/B1) Rattus norvegicus
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Symbol: Hnrnpa2b1
Name: heterogeneous nuclear ribonucleoprotein A2/B1
Description: Exhibits DNA polymerase binding activity; G-rich strand telomeric DNA binding activity; and RNA binding activity. Involved in several processes, including G-quadruplex DNA unwinding; mRNA export from nucleus; and positive regulation of DNA metabolic process. Localizes to several cellular components, including the chromosome; cytoplasm; and nucleus. Used to study rheumatoid arthritis. Biomarker of hepatocellular carcinoma; pancreatic carcinoma; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in inclusion body myopathy with Paget disease of bone and frontotemporal dementia. Orthologous to human HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heterogeneous nuclear ribonucleoprotein A2; heterogeneous nuclear ribonucleoprotein B0a; heterogeneous nuclear ribonucleoprotein B0b; heterogeneous nuclear ribonucleoprotein B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP; hnRNP A2 / hnRNP B1; hnRNP A2/B1; Hnrpa2; Hnrpa2b1; nuclear ribonucleoprotein particle A2 protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0481,237,496 - 81,241,281 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04145,903,680 - 145,907,465 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,700,327 - 79,704,116 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1479,975,786 - 79,982,624 (-)NCBI
Celera475,439,774 - 75,443,559 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hnrnpa2b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310403
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.