Copb2 (COPI coat complex subunit beta 2)

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Gene: Copb2 (COPI coat complex subunit beta 2) Rattus norvegicus

Analyze

Symbol:

Copb2

Name:

COPI coat complex subunit beta 2

RGD ID:

628746

Description:

Exhibits protein kinase C binding activity. Predicted to be involved in Golgi vesicle transport; intracellular protein transport; and toxin transport. Localizes to Golgi membrane. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 19. Orthologous to human COPB2 (COPI coat complex subunit beta 2); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

beta prime COP; beta'-coat protein; beta'-COP; coatomer protein complex subunit beta 2; coatomer protein complex, subunit beta 2 (beta prime); coatomer subunit beta'; MGC93460; p102; Rack2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COPB2 (COPI coat complex subunit beta 2)	HGNC	HomoloGene, NCBI, Panther
Mus musculus (house mouse):	Copb2 (coatomer protein complex, subunit beta 2 (beta prime))	HGNC	NCBI, HomoloGene, Panther
Chinchilla lanigera (long-tailed chinchilla):	Copb2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	COPB2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COPB2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Copb2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COPB2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	COPB2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Copb2 (COPI coat complex subunit beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	COPB2 (COPI coat complex subunit beta 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Copb2 (coatomer protein complex, subunit beta 2 (beta prime))	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	E03H4.8	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SEC27	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	beta'COP	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	copb-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	99,161,324 - 99,183,452 (+)	NCBI
Rnor_6.0	8	106,582,339 - 106,603,763 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	106,024,920 - 106,047,170 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	98,569,531 - 98,591,507 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

blepharophimosis, ptosis, and epicanthus inversus syndrome (ISO)

combined oxidative phosphorylation deficiency (ISO)

combined oxidative phosphorylation deficiency 5 (ISO)

COVID-19 (ISO)

microcephaly (ISS)

primary autosomal recessive microcephaly 19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4-hydroxyphenyl retinamide (ISO)

afimoxifene (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP)

bicalutamide (ISO)

bisphenol A (EXP)

captan (ISO)

cisplatin (ISO)

clofibrate (ISO)

cyclosporin A (ISO)

dexamethasone (EXP)

diarsenic trioxide (ISO)

diazinon (ISO)

dicrotophos (ISO)

ethanol (ISO)

flavonoids (EXP)

flutamide (EXP)

folic acid (ISO)

folpet (ISO)

fulvestrant (ISO)

hydrogen peroxide (ISO)

methamphetamine (EXP)

miconazole (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

paracetamol (ISO)

rac-lactic acid (ISO)

raloxifene (ISO)

Salinomycin (ISO)

sodium arsenate (ISO)

testosterone (EXP)

tetrachloromethane (ISO)

trichloroethene (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum to Golgi vesicle-mediated transport (IBA)

intra-Golgi vesicle-mediated transport (IBA,ISO)

intracellular protein transport (IBA)

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (IBA)

toxin transport (ISO)

Cellular Component

COPI vesicle coat (IBA,ISO)

cytosol (IEA)

exocytic vesicle (ISO)

Golgi apparatus (IDA,ISO)

Golgi membrane (IDA)

Molecular Function

protein binding (IPI,ISO)

protein kinase C binding (IPI)

structural molecule activity (IEA)

References

References - curated


1.	Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2.	Burman JL, etal., J Biol Chem. 2008 Aug 15;283(33):22774-86. doi: 10.1074/jbc.M801869200. Epub 2008 Jun 13.
3.	Csukai M, etal., J Biol Chem 1997 Nov 14;272(46):29200-6.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	GOA data from the GO Consortium
6.	Loh E, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1209-22. Epub 2005 Feb 22.
7.	MGD data from the GO Consortium
8.	RGD automated data pipeline
9.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8335000	PMID:8947846	PMID:12477932	PMID:14729954	PMID:15358183	PMID:16854843	PMID:18434597	PMID:18504258	PMID:19631211	PMID:20724702	PMID:20801885	PMID:22871113
PMID:23716698	PMID:24625528	PMID:25002582

Genomics

Comparative Map Data

Copb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	99,161,324 - 99,183,452 (+)	NCBI
Rnor_6.0	8	106,582,339 - 106,603,763 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	106,024,920 - 106,047,170 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	98,569,531 - 98,591,507 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

COPB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	139,353,946 - 139,389,736 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	3	139,355,600 - 139,389,680 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	139,355,595 - 139,389,680 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	139,076,433 - 139,108,522 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	3	139,076,248 - 139,108,522 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	140,559,123 - 140,591,151 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	140,559,132 - 140,591,159	NCBI
Celera	3	137,499,384 - 137,531,480 (-)	NCBI
Cytogenetic Map	3	q23	NCBI
HuRef	3	136,451,880 - 136,483,977 (-)	NCBI		HuRef
CHM1_1	3	139,039,998 - 139,072,089 (-)	NCBI		CHM1_1

Copb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	98,445,784 - 98,470,428 (+)	NCBI	GRCm39		mm39
GRCm38	9	98,563,731 - 98,588,375 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	98,563,721 - 98,588,382 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	98,464,150 - 98,488,794 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	98,373,083 - 98,397,727 (+)	NCBI			mm8
Celera	9	98,109,355 - 98,134,004 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI

Copb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955508	6,201,989 - 6,231,845 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955508	6,201,989 - 6,231,840 (+)	NCBI	ChiLan1.0	ChiLan1.0

COPB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	143,994,312 - 144,026,277 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	143,994,312 - 144,020,117 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	136,394,480 - 136,426,544 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

COPB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	23	35,536,615 - 35,566,569 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	23	35,536,520 - 35,604,708 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Copb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936540	1,467,169 - 1,493,218 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COPB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	80,218,984 - 80,264,764 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	80,220,460 - 80,264,808 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	87,894,952 - 87,931,027 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COPB2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	51,165,275 - 51,197,971 (+)	NCBI

Copb2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	15,908,551 - 15,936,886 (-)	NCBI

Position Markers

RH129978

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	8	106,603,550 - 106,603,754	NCBI	Rnor6.0
Celera	8	98,591,295 - 98,591,498	UniSTS
RH 3.4 Map	8	1051.7	UniSTS

AU048956

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	8	106,584,071 - 106,584,313	NCBI	Rnor6.0
Celera	8	98,571,234 - 98,571,480	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	9531047	119211942	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10938911	120496129	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	30918112	107206309	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	33558660	109028082	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	33558660	109028082	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	33558660	109028082	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	33558764	113580387	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	44458129	118087517	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	50529480	128036471	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	50529480	128036471	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	50529480	128036471	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	50529480	128036471	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	55435004	115812386	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	59234112	108068306	Rat
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	65717449	128033050	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	72849686	117849686	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight as a percentage of body weight (CMO:0000654)	8	74917593	121080545	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	76103982	127182642	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	78805083	123805083	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	78805083	123805083	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	78805083	123805083	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	78805083	123805083	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	80697934	125697934	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	83894304	128894304	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	89058229	132243842	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	95319530	115625029	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	95963141	122354314	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	100873811	133307652	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	100873811	133307652	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102051964	133307652	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	104682575	133307652	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	104682575	133307652	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	23
Count of miRNA genes:	22
Interacting mature miRNAs:	23
Transcripts:	ENSRNOT00000075603
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF002705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH004876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC064317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_021765 ⟹ NP_068533

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	99,161,324 - 99,183,452 (+)	NCBI
Rnor_6.0	8	106,582,339 - 106,603,763 (+)	NCBI
Rnor_5.0	8	106,024,920 - 106,047,170 (+)	NCBI
Celera	8	98,569,531 - 98,591,507 (+)	RGD

Sequence:

show sequence

AGGTTCCACTGCTCCGTGGGTCTGTGTGTTCTTGAGTACCAGTGTCGCTCGGAGCCTGTGAGAG
GCTGGGGCTCGGACAATCGGAGCCATGCCTCTTCGACTTGACATCAAGAGAAAGCTAACTGCTA
TGTCTGATCGGGTTAAGAGTGTGGATTTGCATCCGACTGAGCCATGGATGCTGGCTAGTCTTTA
CAATGGCAGTGTGTGTGTTTGGAATCATGAAACTCAGACGCTGGTGAAGACCTTTGAAGTGTGT
GATCTCCCTGTTCGAGCTGCGAAGTTTGTCGCAAGGAAGAACTGGGTGGTGACAGGAGCAGATG
ATATGCAGATTAGAGTGTTCAATTATAACACCCTGGAGAGGGTGCACATGTTTGAAGCACACTC
GGATTACATCCGTTGCATTGCTGTTCATCCCACCCAGCCGTTCATTCTCACAAGCAGTGATGAC
ATGCTTATTAAGCTCTGGGACTGGGACAAAAAATGGTCTTGTTCACAAGTGTTTGAAGGACACA
CGCATTATGTTATGCAGATTGTGATAAACCCCAAAGATAACAATCAGTTTGCCAGTGCATCTCT
CGACAGGACCATCAAGGTGTGGCAGCTGGGCTCTTCATCACCAAACTTTACGCTGGAGGGACAT
GAAAAAGGCGTGAATTGCATTGATTACTACAGTGGTGGTGATAAGCCATACCTCATTTCAGGTG
CAGATGACCGGCTCGTTAAAATATGGGATTATCAGAATAAAACTTGTGTGCAGACCCCGGAGGG
ACATGCCCAGAATGTGTCATGCGCAACGTTCCATCCTGAGCTGCCCATCATCATCACAGGGTCG
GAAGACGGAACGGTGCGAATTTGGCACTCCAGCACCTACCGGCTGGAGAGCACACTGAATTACG
GAATGGAGCGAGTGTGGTGTGTGGCCAGTCTGAGAGGCTCCAACAATGTCGCTCTGGGCTACGA
TGAAGGGAGCATCATTGTTAAGCTTGGTCGGGAGGAACCTGCCATGTCCATGGATGCCAATGGA
AAGATAATCTGGGCCAAGCATTCAGAGGTCCAGCAGGCCAACCTGAAAGCAATGGGTGACACCG
AAATTAAAGATGGAGAAAGACTGCCACTAGCAGTAAAGGATATGGGCAGCTGTGAAATATATCC
ACAGACCATTCAGCACAATCCTAATGGGAGGTTTGTCGTGGTGTGTGGTGATGGAGAATATATC
ATCTACACAGCAATGGCCTTGAGAAACAAGAGCTTTGGATCTGCCCAGGAGTTTGCATGGGCCC
ACGATTCTTCAGAGTATGCAATAAGAGAAAGCAACAGTGTTGTAAAGATATTTAAGAACTTTAA
GGAAAAGAAATCATTTAAACCTGATTTTGGAGCTGAAAGTATCTATGGGGGCTTCTTGCTGGGA
GTCAGGTCTGTAAATGGCTTAGCATTCTATGACTGGGAGAATACCGAACTCATCCGCAGAATTG
AAATTCAGCCCAAGCACATCTTCTGGTCTGACTCTGGAGAGCTGGTCTGTATTGCCACCGAGGA
GTCATTTTTTATTCTTAAATATCTGTCAGAAAAAGTCTTGGCTGCACAGGAAACCCACGAGGGA
GTTACTGAGGATGGCATTGAGGACGCCTTTGAGGTTCTTGGTGAAATTCAGGAAATTGTGAAAA
CTGGGCTGTGGGTAGGTGACTGCTTCATCTACACAAGTTCTGTGAACAGATTAAACTATTATGT
GGGAGGCGAGATTGTCACCATTGCCCACTTGGACAGGACAATGTACCTTCTGGGCTATATTCCA
AAAGACAATAGGCTTTATCTGGGAGATAAAGAATTGAACATAGTTAGCTACTCCCTGTTAGTTT
CAGTCCTGGAATACCAGACTGCTGTCATGCGGAGGGATTTCAGCATGGCTGATAAGGTGCTCCC
TACTATCCCAAAAGAACAGAGGACCAGAGTTGCACACTTTTTGGAAAAGCAGGGCTTCAAGCAG
CAAGCACTCACAGTATCCACAGATCCTGAACATCGTTTTGAGCTTGCTCTTCAACTTGGGGAGC
TGAAAATTGCTTACCAGTTAGCAGTGGAGGCAGAGTCGGAGCAGAAGTGGAAACAACTTGCCGA
ACTTGCCATTAGTAAATGTCAGTTCAGCCTAGCCCAGGAGTGTTTGCACCATGCCCAGGACTAC
GGTGGTCTGCTGCTCTTGGCCACTGCCTCTGGAAACGCTAGTATGGTGAACAAGCTGGCAGAAG
GTGCGGAGAGAGATGGCAAAAATAACGTGGCATTCATGAGCTATTTTTTACAGGGCAAGCTTGA
TGCTTGCCTAGAGCTCTTGATCAGAACAGGAAGACTCCCAGAAGCCGCCTTCCTGGCCCGAACT
TACTTACCCAGCCAGGTCTCAAGGGTAGTGAAGTTGTGGAGGGAGAATCTCTCAAAAGTCAACC
AGAAAGCAGCAGAATCCCTCGCTGACCCCACAGAGTATGAAAACCTTTTCCCTGGATTAAAAGA
AGCCTTTGTTGTTGAAGAATGGGTGAAGGAGACACATGCGGATCTGTGGCCAGCCAAGCAGTAC
CCTCTTGTCACGCCAAATGAAGAGAGAAATGTTATGGAAGAGGCAAAACGGTTTCAGCCCTCAA
GAGCCACAGCTCAGCAGGAACCTGATGGGAAACCAGCTTCTAGCCCAGTTATCATGGCCTCCCA
AACCACTCACAAAGAAGAAAAGAGTTTCCAGGAACTAGAAGATGATTTAGATACCATGGAATTA
GAGGATATTGATACAACAGACATCAATCTGGATGAAGATATTCTGGATGACTAAAGTTTGCCAT
TTACTCCAGTAAGAGATTATGATGGCACATACAAATCAGTCACCACCCTGACCAGAACTGTGGC
AATCCTTGCTCTGCACACGTAAACAAGGAGGAACATAGCCCCTTCATCTTCAGGGCAGAGTTTT
AACTGAAACAGACACTTGTGCTTTTTTCATATTGTCATTAAACCACCCCTCATAAAAAAAAAAA
AAAAAAAAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_068533	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB38315	(Get FASTA)	NCBI Sequence Viewer
	AAB88018	(Get FASTA)	NCBI Sequence Viewer
	AAH88397	(Get FASTA)	NCBI Sequence Viewer
	O35142	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_068533 ⟸ NM_021765

- Sequence:

show sequence

MPLRLDIKRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAK
FVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDW
DKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCID
YYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIW
HSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHS
EVQQANLKAMGDTEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALR
NKSFGSAQEFAWAHDSSEYAIRESNSVVKIFKNFKEKKSFKPDFGAESIYGGFLLGVRSVNGLA
FYDWENTELIRRIEIQPKHIFWSDSGELVCIATEESFFILKYLSEKVLAAQETHEGVTEDGIED
AFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLG
DKELNIVSYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQALTVSTD
PEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFSLAQECLHHAQDYGGLLLLAT
ASGNASMVNKLAEGAERDGKNNVAFMSYFLQGKLDACLELLIRTGRLPEAAFLARTYLPSQVSR
VVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEE
RNVMEEAKRFQPSRATAQQEPDGKPASSPVIMASQTTHKEEKSFQELEDDLDTMELEDIDTTDI
NLDEDILDD

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Protein Domains

WD_REPEATS_REGION

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628746	AgrOrtholog
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7190660	IMAGE-MGC_LOAD
InterPro	Coatomer_WD-assoc_reg	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	COPB2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60384	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93460	IMAGE-MGC_LOAD
NCBI Gene	60384	ENTREZGENE
Pfam	Coatomer_WDAD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Copb2	PhenoGen
PIRSF	Coatomer_beta'_subunit	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	WD_REPEATS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	COPB2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q5M7X1_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-11-11	Copb2	COPI coat complex subunit beta 2	Copb2	coatomer protein complex subunit beta 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-04-13	Copb2	coatomer protein complex subunit beta 2	Copb2	coatomer protein complex, subunit beta 2 (beta prime)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Copb2	coatomer protein complex, subunit beta 2 (beta prime)		beta prime COP	Name updated	1299863	APPROVED
2003-02-27	Copb2	beta prime COP			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM