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Gene: Gabrq (gamma-aminobutyric acid type A receptor subunit theta) Rattus norvegicus

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Symbol:

Gabrq

Name:

gamma-aminobutyric acid type A receptor subunit theta

RGD ID:

68331

Description:

Predicted to enable GABA-A receptor activity and GABA-gated chloride ion channel activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of GABA-A receptor complex. Orthologous to human GABRQ (gamma-aminobutyric acid type A receptor subunit theta); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

gamma-aminobutyric acid (GABA) A receptor theta; gamma-aminobutyric acid (GABA) A receptor, theta; gamma-aminobutyric acid (GABA) receptor, theta; gamma-aminobutyric acid (GABA-A) receptor, subunit theta; gamma-aminobutyric acid A receptor, theta; gamma-aminobutyric acid receptor subunit theta; gamma-aminobutyric acid type A receptor theta subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	155,737,838 - 155,755,225 (+)	NCBI		GRCr8
mRatBN7.2	X	150,696,161 - 150,712,948 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	150,696,427 - 150,709,919 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	152,888,448 - 152,900,925 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	156,420,788 - 156,433,265 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	153,963,894 - 153,976,377 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	152,852,230 - 152,869,012 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	152,852,506 - 152,864,975 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	148,583,050 - 148,599,817 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	158,843,492 - 158,855,961 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	158,916,924 - 158,929,394 (+)	NCBI
Celera	1	131,660,367 - 131,672,836 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

factor VIII deficiency (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

6-propyl-2-thiouracil (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

diazepam (EXP)

diethylstilbestrol (EXP)

fructose (ISO)

gamma-aminobutyric acid (EXP)

glucose (ISO)

glyphosate (ISO)

ketoconazole (EXP)

lead diacetate (EXP)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transmembrane transport (IBA)

chloride transport (IEA)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

Cellular Component

chloride channel complex (IEA)

GABA-A receptor complex (IBA)

membrane (IEA)

plasma membrane (IEA)

receptor complex (IEA,ISO)

Molecular Function

chloride channel activity (IBA,IEA)

extracellular ligand-gated monoatomic ion channel activity (IEA)

GABA-A receptor activity (IBA,IEA,ISO)

GABA-gated chloride ion channel activity (IEA,ISO)

monoatomic ion channel activity (IEA)

protein binding (ISO)

transmembrane signaling receptor activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus.	Sinkkonen ST, etal., J Neurosci 2000 May 15;20(10):3588-95.

Additional References at PubMed

PMID:19249336	PMID:23382219

Genomics

Comparative Map Data

Gabrq
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	155,737,838 - 155,755,225 (+)	NCBI		GRCr8
mRatBN7.2	X	150,696,161 - 150,712,948 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	150,696,427 - 150,709,919 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	152,888,448 - 152,900,925 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	156,420,788 - 156,433,265 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	153,963,894 - 153,976,377 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	152,852,230 - 152,869,012 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	152,852,506 - 152,864,975 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	148,583,050 - 148,599,817 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	158,843,492 - 158,855,961 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	158,916,924 - 158,929,394 (+)	NCBI
Celera	1	131,660,367 - 131,672,836 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

GABRQ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	152,637,895 - 152,658,965 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	152,637,895 - 152,657,542 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	151,806,349 - 151,826,007 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	151,557,293 - 151,572,481 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	151,477,204 - 151,492,393	NCBI
Celera	X	152,051,839 - 152,067,018 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	140,659,584 - 140,674,760 (+)	NCBI		HuRef
CHM1_1	X	151,681,317 - 151,696,496 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	150,904,491 - 150,933,803 (+)	NCBI		T2T-CHM13v2.0

Gabrq
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	71,868,769 - 71,886,213 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	71,868,784 - 71,886,208 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	72,825,163 - 72,842,607 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	72,825,178 - 72,842,602 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	70,070,775 - 70,083,883 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	69,078,156 - 69,091,264 (+)	NCBI		MGSCv36	mm8
Celera	X	63,768,918 - 63,782,292 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	37.29	NCBI

Gabrq
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955498	8,048,265 - 8,064,239 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955498	8,048,012 - 8,064,239 (+)	NCBI	ChiLan1.0	ChiLan1.0

GABRQ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	152,695,806 - 152,715,495 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	152,699,409 - 152,719,101 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	142,205,996 - 142,225,571 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	152,160,173 - 152,179,774 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	152,159,961 - 152,179,774 (+)	Ensembl	panpan1.1		panPan2

GABRQ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	120,607,815 - 120,630,251 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	120,607,686 - 120,628,343 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	105,986,731 - 106,009,002 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	122,830,162 - 122,852,448 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	122,829,884 - 122,850,544 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	119,549,100 - 119,571,365 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	122,039,877 - 122,062,152 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	121,914,807 - 121,937,084 (+)	NCBI		UU_Cfam_GSD_1.0

Gabrq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	117,923,763 - 117,940,883 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936714	318,676 - 332,357 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936714	315,585 - 332,629 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GABRQ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	123,834,997 - 123,850,278 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	123,834,884 - 123,855,187 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	141,305,459 - 141,323,254 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GABRQ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	127,201,371 - 127,217,964 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	127,210,446 - 127,219,804 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	65,060,292 - 65,079,959 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gabrq
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624883	3,903,661 - 3,918,836 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624883	3,903,389 - 3,922,736 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gabrq
3 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	17
Count of miRNA genes:	17
Interacting mature miRNAs:	17
Transcripts:	ENSRNOT00000022880
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat

Markers in Region

UniSTS:496008

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	X	155,749,641 - 155,749,733 (+)	Marker Load Pipeline
mRatBN7.2	X	150,707,366 - 150,707,457 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	152,863,431 - 152,863,521	NCBI	Rnor6.0
Rnor_5.0	1	148,594,236 - 148,594,326	UniSTS	Rnor5.0
RGSC_v3.4	X	158,854,417 - 158,854,507	UniSTS	RGSC3.4
Celera	1	131,671,292 - 131,671,382	UniSTS
Cytogenetic Map	X	q37	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
4	6	44	102	42	47	20	14	20	2	122	67	93	26	49	27

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF189261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF419333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000078419 ⟹ ENSRNOP00000068820

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	150,696,427 - 150,708,911 (+)	Ensembl
Rnor_6.0 Ensembl	X	152,852,506 - 152,864,975 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107625 ⟹ ENSRNOP00000089871

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	150,696,427 - 150,709,919 (+)	Ensembl

RefSeq Acc Id:

NM_031733 ⟹ NP_113921

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	155,738,436 - 155,755,223 (+)	NCBI
mRatBN7.2	X	150,696,161 - 150,712,948 (+)	NCBI
Rnor_6.0	X	152,852,506 - 152,864,975 (+)	NCBI
Rnor_5.0	1	148,583,050 - 148,599,817 (+)	NCBI
RGSC_v3.4	X	158,843,492 - 158,855,961 (+)	RGD
Celera	1	131,660,367 - 131,672,836 (+)	NCBI

Sequence:

show sequence

ATGCTGCGAGCCGCTGAGCTCCTGCTGCTCATTAGGACTTGGCTGGCAGAGAGTAACGACCCCA
GTCCCACCCCAAAATTCCACTTCGAGCTCTCCTCCAGCATGCCTGAAGTCATCCTGGATCTCTT
CAACTGCAAAAATTGTGCAAATGAAGCTGTTGTTCAAAAGATTTTGGACAGGGTCCTGTCAACA
TATGATGTCCGACTGAGACCAAATTTTGGAGGAGCACCTGTGCCTGTGTCAATATCTATCTATG
TCTCCAGTATTGAACAGATCTCAGAAATAAACATGGACTATACCATCACAATGTTTCTGCATCA
GACTTGGAAGGACACGCGCTTAGCTTACTATGAGACCAACCTGAACCTGACTCTGGACTATCGG
ATGCATGAGAAGCTCTGGGTCCCTGACTGCTACTTTGTGAATAGCAAAGATGCCTTTGTGCATG
ATGTAACTGCGGAGAATCGTGTATTTCAACTTCACCCAGATGGGACAGTGCAATATGGCATCCG
ACTTACCACAACAGCAGCCTGTTCCCTGGATCTGCAAAAATTCCCTATGGACAAACAATCCTGC
AAGCTGGAGGTGGAGAGCTATGGCTACACTGTCGAAGACATTGTGTTATCCTGGGAAGATGATA
ATGCCATCCACATTACTGACGAGCTACACATCCCTCAGTACACCTACCTGGGGAGGACAATTAC
CAGCAAGGAGGTGTACTTCTACACAGGCTCCTACATGCGCCTGATAGTGAAGTTCCAGGTTCAG
AGGGAAGTCCGCAGTTACCTTGTGCAGGTCTATTGGCCCACAGTCCTCACCACCATTCTCTCCT
GGATATCATTTTGGATGAACTATGGTTCCTCTGCAGCCAGGGTAACTATTGGACTAACTTCAAT
CCTTGTCCTGACTACCATCGACTCACATATGCGGGATAAACTCCCCCATATTTCCTGTATCAAA
GCCATTGACATCTACATCCTTGTGTGCCTGTTCTTCGTTTTCCTGTCCCTGCTGGAGTATGTCT
ACATCAACTACCTTTTCTTCAGCCAAGCACCTCGGCGTAATCACAGGAGATGCAGGAAACCCAG
GAGAGTTGTTGCCCGATACCGCTACCAAGAAGTGGTGGTAGCACATGTGCAGGATGGCCTGATA
AATGTGGAAGACAGAGTGGAAGACAGAGCTGGTCCCCTTCCTGACAGCCCCATGCAGGCTCATC
TGGCAAGCCAGGAAAGTCTAGGATCTTTGTTGTTCACTTCAGAGGAGGCTCAACTGGCTACTTC
AGAAAGCCTCAGCCTACTCTCGTCTGCCTCAAGCCAGGTCCAATTGGCCACTGGAGAAAGCCTG
GGTGATCTGCCCTCCACCTCTGAGCAAACACTGCCTGACTATACCATTCACTTTCATGGTTTTC
TCACTAATGACAGTATTCTCCCCATCAAAATCCGCAGCCATTCTGATGCCCTGGGTGATGAAGA
CTCCGAAGAAAGCCTAAGCTCTGAGGAGAGCTATGGCCATGGAGGCAGCCCCACTGGAAGGCTC
AAGCTCCAGATTAGCCAGAGGTGTGTGCAAGAAGCAAGTTGGGACATTGATAAGATTGAGAGCT
TACAGGATGACATCAGTATCAAGAGCAGCTGGCTTGGCCTTGATGAACAACGCAAAGGGGATGC
TGACAGTATCTGGAGCCTTACTGATGAGGAGCTCATGGCCTGTGACCAAGAGAAGGACAGTAGC
AGTAGCTCAGAGTCTGAGGAGAGTTGCTCCCCAAGCCCTGGGTGCTCCTTCAATGAAGGGTTCT
CTTTTCAGCTCTTTAACCCTAACCGGGTCCCTAAGGTTGACAGGTGGTCCCGTTTCCTCTTCCC
TCTTTCCTTTGGGTTGTTCAATGTGGTTTACTGGTTATACCATATGTATTAG

hide sequence

RefSeq Acc Id:

XM_063280286 ⟹ XP_063136356

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	155,737,838 - 155,755,225 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_113921	(Get FASTA)	NCBI Sequence Viewer
	XP_063136356	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF70382	(Get FASTA)	NCBI Sequence Viewer
	AAL15939	(Get FASTA)	NCBI Sequence Viewer
	EDL82834	(Get FASTA)	NCBI Sequence Viewer
	EDL82835	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068820
	ENSRNOP00000068820.2
	ENSRNOP00000089871
	ENSRNOP00000089871.1

RefSeq Acc Id:	NP_113921 ⟸ NM_031733
- Peptide Label:	precursor
- UniProtKB:	Q91ZM7 (UniProtKB/TrEMBL), G3V875 (UniProtKB/TrEMBL), A6KSY1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLRAAELLLLIRTWLAESNDPSPTPKFHFELSSSMPEVILDLFNCKNCANEAVVQKILDRVLST YDVRLRPNFGGAPVPVSISIYVSSIEQISEINMDYTITMFLHQTWKDTRLAYYETNLNLTLDYR MHEKLWVPDCYFVNSKDAFVHDVTAENRVFQLHPDGTVQYGIRLTTTAACSLDLQKFPMDKQSC KLEVESYGYTVEDIVLSWEDDNAIHITDELHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQ REVRSYLVQVYWPTVLTTILSWISFWMNYGSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIK AIDIYILVCLFFVFLSLLEYVYINYLFFSQAPRRNHRRCRKPRRVVARYRYQEVVVAHVQDGLI NVEDRVEDRAGPLPDSPMQAHLASQESLGSLLFTSEEAQLATSESLSLLSSASSQVQLATGESL GDLPSTSEQTLPDYTIHFHGFLTNDSILPIKIRSHSDALGDEDSEESLSSEESYGHGGSPTGRL KLQISQRCVQEASWDIDKIESLQDDISIKSSWLGLDEQRKGDADSIWSLTDEELMACDQEKDSS SSSESEESCSPSPGCSFNEGFSFQLFNPNRVPKVDRWSRFLFPLSFGLFNVVYWLYHMY hide sequence

Ensembl Acc Id:

ENSRNOP00000068820 ⟸ ENSRNOT00000078419

Ensembl Acc Id:

ENSRNOP00000089871 ⟸ ENSRNOT00000107625

RefSeq Acc Id:	XP_063136356 ⟸ XM_063280286
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GHR1 (UniProtKB/TrEMBL)

Protein Domains

Neurotransmitter-gated ion-channel ligand-binding Neurotransmitter-gated ion-channel transmembrane

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V875-F1-model_v2	AlphaFold	G3V875	1-635	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:68331	AgrOrtholog
BioCyc Gene	G2FUF-696	BioCyc
Ensembl Genes	ENSRNOG00000053402	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000078419	ENTREZGENE
	ENSRNOT00000078419.2	UniProtKB/TrEMBL
	ENSRNOT00000107625	ENTREZGENE
	ENSRNOT00000107625.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.390	UniProtKB/TrEMBL
	2.70.170.10	UniProtKB/TrEMBL
InterPro	GABAA_rcpt	UniProtKB/TrEMBL
	GABAAt_rcpt	UniProtKB/TrEMBL
	Neur_chan_lig-bd	UniProtKB/TrEMBL
	Neur_chan_lig-bd_sf	UniProtKB/TrEMBL
	Neur_channel	UniProtKB/TrEMBL
	Neuro-gated_channel_TM_sf	UniProtKB/TrEMBL
	Neuro_actylchol_rec	UniProtKB/TrEMBL
	Neurotrans-gated_channel_TM	UniProtKB/TrEMBL
	Neurotransmitter_ion_chnl_CS	UniProtKB/TrEMBL
KEGG Report	rno:65187	UniProtKB/TrEMBL
NCBI Gene	65187	ENTREZGENE
PANTHER	PTHR18945	UniProtKB/TrEMBL
Pfam	Neur_chan_LBD	UniProtKB/TrEMBL
	Neur_chan_memb	UniProtKB/TrEMBL
PhenoGen	Gabrq	PhenoGen
PRINTS	GABAARECEPTR	UniProtKB/TrEMBL
	GABAARTHETA	UniProtKB/TrEMBL
	NRIONCHANNEL	UniProtKB/TrEMBL
PROSITE	NEUROTR_ION_CHANNEL	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000053402	RatGTEx
Superfamily-SCOP	Neu_channel_TM	UniProtKB/TrEMBL
	Neur_chan_LBD	UniProtKB/TrEMBL
UniProt	A0A8I6GHR1	ENTREZGENE, UniProtKB/TrEMBL
	A6KSY1	ENTREZGENE, UniProtKB/TrEMBL
	A6KSY2_RAT	UniProtKB/TrEMBL
	G3V875	ENTREZGENE, UniProtKB/TrEMBL
	Q91ZM7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-12-06	Gabrq	gamma-aminobutyric acid type A receptor subunit theta	Gabrq	gamma-aminobutyric acid type A receptor theta subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Gabrq	gamma-aminobutyric acid type A receptor theta subunit	Gabrq	gamma-aminobutyric acid (GABA) A receptor, theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-16	Gabrq	gamma-aminobutyric acid (GABA) A receptor, theta	Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-17	Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	Gabrq	gamma-aminobutyric acid (GABA-A) receptor, subunit theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-11	Gabrq	gamma-aminobutyric acid (GABA-A) receptor, subunit theta	Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-18	Gabrq	gamma-aminobutyric acid (GABA) receptor, theta	Gabrq	gamma-aminobutyric acid A receptor, theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Gabrq	gamma-aminobutyric acid A receptor, theta			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	mRNA localized in the rat locus ceruleus and the hypothalamus	68250
gene_homology	has low sequence conservation with human protein and may have significantly different functions	68250

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar