Vamp5 (vesicle-associated membrane protein 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Vamp5 (vesicle-associated membrane protein 5) Rattus norvegicus
Analyze
Symbol: Vamp5
Name: vesicle-associated membrane protein 5
RGD ID: 620419
Description: Predicted to be involved in Golgi to plasma membrane protein transport. Predicted to act upstream of or within skeletal muscle tissue development. Located in trans-Golgi network. Orthologous to human VAMP5 (vesicle associated membrane protein 5); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: myobrevin; VAMP-5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,982,004 - 105,993,247 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4105,982,009 - 105,993,247 (-)EnsemblGRCr8
mRatBN7.24104,423,813 - 104,435,059 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4104,423,820 - 104,426,212 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4109,804,079 - 109,815,395 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,579,195 - 105,590,508 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04104,193,451 - 104,204,843 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04100,231,561 - 100,232,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4100,231,561 - 100,232,559 (-)Ensemblrn6Rnor6.0
Rnor_5.04165,002,320 - 165,003,319 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44105,673,889 - 105,674,892 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera493,578,068 - 93,579,067 (-)NCBICelera
RGSC_v3.14105,918,369 - 105,919,371 (-)NCBI
Cytogenetic Map4q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
crocidolite asbestos  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
flavonoids  (EXP)
fulvestrant  (ISO)
gentamycin  (EXP)
ketoconazole  (EXP)
lead diacetate  (EXP)
maneb  (ISO)
melatonin  (ISO)
methimazole  (EXP)
nickel sulfate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network. Zeng Q, etal., J Biol Chem 2003 Jun 20;278(25):23046-54. Epub 2003 Apr 6.
7. A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. Zeng Q, etal., Mol Biol Cell 1998 Sep;9(9):2423-37.
Additional References at PubMed
PMID:19675279   PMID:20458337   PMID:20582536   PMID:21151919   PMID:23180306   PMID:23376485   PMID:31505169  


Genomics

Comparative Map Data
Vamp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,982,004 - 105,993,247 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4105,982,009 - 105,993,247 (-)EnsemblGRCr8
mRatBN7.24104,423,813 - 104,435,059 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4104,423,820 - 104,426,212 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4109,804,079 - 109,815,395 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,579,195 - 105,590,508 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04104,193,451 - 104,204,843 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04100,231,561 - 100,232,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4100,231,561 - 100,232,559 (-)Ensemblrn6Rnor6.0
Rnor_5.04165,002,320 - 165,003,319 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44105,673,889 - 105,674,892 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera493,578,068 - 93,579,067 (-)NCBICelera
RGSC_v3.14105,918,369 - 105,919,371 (-)NCBI
Cytogenetic Map4q32NCBI
VAMP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38285,584,431 - 85,593,406 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl285,584,431 - 85,593,406 (+)Ensemblhg38GRCh38
GRCh37285,811,554 - 85,820,529 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,665,042 - 85,674,022 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34285,723,188 - 85,732,169NCBI
Celera285,639,815 - 85,648,795 (+)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef285,708,672 - 85,717,650 (+)NCBIHuRef
CHM1_1285,741,337 - 85,750,317 (+)NCBICHM1_1
T2T-CHM13v2.0285,586,491 - 85,595,466 (+)NCBIT2T-CHM13v2.0
Vamp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,345,032 - 72,357,451 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl672,345,777 - 72,357,451 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38672,368,049 - 72,380,468 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,368,794 - 72,380,468 (-)Ensemblmm10GRCm38
MGSCv37672,318,043 - 72,330,462 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36672,298,537 - 72,309,901 (-)NCBIMGSCv36mm8
Celera674,458,535 - 74,470,793 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
Vamp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,911,711 - 1,912,874 (-)Ensembl
ChiLan1.0NW_0049554241,911,711 - 1,912,865 (-)NCBIChiLan1.0ChiLan1.0
VAMP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21240,789,269 - 40,798,238 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A40,792,030 - 40,801,023 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A85,634,555 - 85,646,120 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A87,187,569 - 87,196,530 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,187,569 - 87,196,532 (+)EnsemblpanPan2panpan1.1
VAMP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11739,488,877 - 39,495,795 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1739,488,938 - 39,495,730 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1739,160,247 - 39,167,171 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01740,235,506 - 40,242,449 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11739,365,034 - 39,371,972 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01739,437,087 - 39,443,998 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01739,836,669 - 39,843,611 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vamp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,172,258 - 79,179,181 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,679,232 - 1,686,268 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,679,276 - 1,686,157 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAMP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl359,175,872 - 59,178,861 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1359,177,460 - 59,185,703 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2362,238,570 - 62,246,620 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VAMP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,563,300 - 21,572,651 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,562,847 - 21,572,340 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604590,896,395 - 90,905,527 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vamp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474917,546,713 - 17,556,010 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474917,546,713 - 17,556,045 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Vamp5
39 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:58
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000016984
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4103194805112478794Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat

Markers in Region
RH141198  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24104,423,930 - 104,424,116 (+)MAPPERmRatBN7.2
Rnor_6.04100,231,431 - 100,231,616NCBIRnor6.0
Rnor_5.04165,002,190 - 165,002,375UniSTSRnor5.0
RGSC_v3.44105,673,759 - 105,673,944UniSTSRGSC3.4
Celera493,577,938 - 93,578,123UniSTS
RH 3.4 Map4648.2UniSTS
Cytogenetic Map4q33UniSTS
RH140679  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84105,982,285 - 105,983,191 (+)Marker Load Pipeline
mRatBN7.24104,424,094 - 104,425,000 (+)MAPPERmRatBN7.2
Rnor_6.04100,231,595 - 100,232,500NCBIRnor6.0
Rnor_5.04165,002,354 - 165,003,259UniSTSRnor5.0
RGSC_v3.44105,673,923 - 105,674,830UniSTSRGSC3.4
Celera493,578,102 - 93,579,007UniSTS
RH 3.4 Map4649.61UniSTS
Cytogenetic Map4q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 152 88 90 59 92 59 6 354 191 11 132 81 83 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000016984   ⟹   ENSRNOP00000016984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4105,982,009 - 105,993,247 (-)Ensembl
mRatBN7.2 Ensembl4104,423,820 - 104,426,212 (-)Ensembl
Rnor_6.0 Ensembl4100,231,561 - 100,232,559 (-)Ensembl
RefSeq Acc Id: NM_053555   ⟹   NP_446007
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,982,004 - 105,993,247 (-)NCBI
mRatBN7.24104,423,813 - 104,435,059 (-)NCBI
Rnor_6.04100,231,561 - 100,232,560 (-)NCBI
Rnor_5.04165,002,320 - 165,003,319 (-)NCBI
RGSC_v3.44105,673,889 - 105,674,892 (-)RGD
Celera493,578,068 - 93,579,067 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_446007 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC97474 (Get FASTA)   NCBI Sequence Viewer  
  EDL91033 (Get FASTA)   NCBI Sequence Viewer  
  EDL91034 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016984
GenBank Protein Q9Z2J5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446007   ⟸   NM_053555
- UniProtKB: Q9Z2J5 (UniProtKB/Swiss-Prot),   A6IAB5 (UniProtKB/TrEMBL),   A0A140TAB7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016984   ⟸   ENSRNOT00000016984
Protein Domains
v-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2J5-F1-model_v2 AlphaFold Q9Z2J5 1-102 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620419 AgrOrtholog
BioCyc Gene G2FUF-44149 BioCyc
Ensembl Genes ENSRNOG00000012659 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000016984 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
InterPro Synaptobrevin UniProtKB/Swiss-Prot
  Synaptobrevin/VAMP UniProtKB/Swiss-Prot
  V_SNARE_CC UniProtKB/Swiss-Prot
  Vamp5 UniProtKB/Swiss-Prot
  VAMP5_R-SNARE_ UniProtKB/Swiss-Prot
KEGG Report rno:89818 UniProtKB/Swiss-Prot
NCBI Gene 89818 ENTREZGENE
PANTHER PTHR47462 UniProtKB/Swiss-Prot
  VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 UniProtKB/Swiss-Prot
Pfam Synaptobrevin UniProtKB/Swiss-Prot
PhenoGen Vamp5 PhenoGen
PIRSF Synaptobrevin_euk UniProtKB/Swiss-Prot
PRINTS SYNAPTOBREVN UniProtKB/Swiss-Prot
PROSITE SYNAPTOBREVIN UniProtKB/Swiss-Prot
  V_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012659 RatGTEx
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
UniProt A0A140TAB7 ENTREZGENE, UniProtKB/TrEMBL
  A6IAB5 ENTREZGENE, UniProtKB/TrEMBL
  A6IAB6_RAT UniProtKB/TrEMBL
  Q9Z2J5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Vamp5  vesicle-associated membrane protein 5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Vamp5  vesicle-associated membrane protein 5      Symbol and Name status set to provisional 70820 PROVISIONAL