Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of JPT2 mRNA | CTD | PMID:28960355 | 17beta-estradiol | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [JPT2 protein binds to ESR1 protein] | CTD | PMID:27156127 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Jpt2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of JPT2 mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of JPT2 mRNA | CTD | PMID:33387578 | 2-hydroxypropanoic acid | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of JPT2 mRNA | CTD | PMID:30851411 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of JPT2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of HN1L mRNA and Propylthiouracil results in increased expression of JPT2 mRNA | CTD | PMID:24780913 and PMID:30047161 | aflatoxin B1 | increases methylation | ISO | JPT2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of JPT2 gene | CTD | PMID:27153756 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of HN1L mRNA | CTD | PMID:30047161 | arsane | affects methylation | ISO | JPT2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of JPT2 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | JPT2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of JPT2 gene | CTD | PMID:25304211 | benzatropine | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein | CTD | PMID:34122009 | benzo[a]pyrene | increases methylation | ISO | Jpt2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of JPT2 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | JPT2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of JPT2 mRNA | CTD | PMID:20678512 | bisphenol A | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of JPT2 protein | CTD | PMID:37567409 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of JPT2 mRNA | CTD | PMID:25181051 | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of JPT2 mRNA | CTD | PMID:24136188 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of JPT2 promoter | CTD | PMID:22457795 | carbamazepine | affects expression | ISO | JPT2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of JPT2 mRNA | CTD | PMID:25979313 | carbon nanotube | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | copper atom | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of JPT2 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of JPT2 mRNA | CTD | PMID:20971185 | Cuprizon | affects expression | EXP | | 6480464 | Cuprizone affects the expression of JPT2 mRNA | CTD | PMID:26577399 | Cuprizon | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein | CTD | PMID:34122009 | cyclosporin A | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of JPT2 mRNA | CTD | PMID:25562108 | diazinon | increases methylation | ISO | JPT2 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of JPT2 gene | CTD | PMID:22964155 | dibutyl phthalate | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of JPT2 mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Jpt2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of JPT2 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of JPT2 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of JPT2 protein | CTD | PMID:23301498 | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of JPT2 mRNA | CTD | PMID:34044035 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of JPT2 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of JPT2 mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | ISO | JPT2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of JPT2 protein | CTD | PMID:37730182 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of JPT2 gene | CTD | PMID:22079235 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of JPT2 mRNA | CTD | PMID:24136188 | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of JPT2 mRNA | CTD | PMID:24915197 | ivermectin | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of JPT2 protein | CTD | PMID:32959892 | lead diacetate | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | lead acetate results in decreased expression of JPT2 mRNA | CTD | PMID:22613225 | lead(0) | affects expression | ISO | JPT2 (Homo sapiens) | 6480464 | Lead affects the expression of JPT2 mRNA | CTD | PMID:28903495 | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of JPT2 protein | CTD | PMID:30467583 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of HN1L mRNA | CTD | PMID:30047161 | methotrexate | increases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of JPT2 mRNA | CTD | PMID:24449571 | miconazole | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Miconazole results in increased expression of JPT2 mRNA | CTD | PMID:27462272 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of JPT2 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | Jpt2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of JPT2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of JPT2 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Jpt2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of JPT2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of JPT2 mRNA | CTD | PMID:29246445 | paracetamol | multiple interactions | ISO | Jpt2 (Mus musculus) | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of JPT2 mRNA] | CTD | PMID:29246445 | pentachlorophenol | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of JPT2 mRNA | CTD | PMID:23892564 | perfluorohexanesulfonic acid | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of JPT2 mRNA | CTD | PMID:37995155 | phenobarbital | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of JPT2 mRNA | CTD | PMID:19270015 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of HN1L mRNA | CTD | PMID:30047161 | quercitrin | increases expression | ISO | JPT2 (Homo sapiens) | 6480464 | quercitrin results in increased expression of JPT2 mRNA | CTD | PMID:25193878 | rac-lactic acid | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of JPT2 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenate | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of JPT2 mRNA | CTD | PMID:30953684 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of HN1L mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of JPT2 mRNA | CTD | PMID:31533062 | tert-butyl hydroperoxide | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of JPT2 mRNA | CTD | PMID:15336504 | tetrachloromethane | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of JPT2 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of JPT2 mRNA | CTD | PMID:31150632 | tetrahydropalmatine | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | tetrahydropalmatine results in decreased expression of JPT2 protein | CTD | PMID:20109541 | titanium dioxide | increases expression | ISO | Jpt2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of JPT2 mRNA | CTD | PMID:23557971 | titanium dioxide | decreases expression | ISO | Jpt2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of JPT2 mRNA | CTD | PMID:29264374 | topotecan | affects response to substance | ISO | JPT2 (Homo sapiens) | 6480464 | JPT2 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | torcetrapib | increases expression | ISO | JPT2 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of JPT2 mRNA | CTD | PMID:23228038 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of JPT2 gene | CTD | PMID:27618143 | trichostatin A | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of JPT2 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JPT2 mRNA | CTD | PMID:27188386 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of JPT2 mRNA | CTD | PMID:30589522 | valproic acid | affects expression | ISO | JPT2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of JPT2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | JPT2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of JPT2 mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | ISO | JPT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JPT2 mRNA | CTD | PMID:27188386 | |