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Gene: Ninj1 (ninjurin 1) Rattus norvegicus

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Symbol:

Ninj1

Name:

ninjurin 1

RGD ID:

3179

Description:

Enables cell adhesion mediator activity. Involved in cell adhesion and positive regulation of angiogenesis. Predicted to be located in filopodium membrane and synaptic membrane. Predicted to be active in extracellular region and plasma membrane. Orthologous to human NINJ1 (ninjurin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; 2-methoxyethanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

nerve injury-induced protein 1; Ninjurin; ninjurin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NINJ1 (ninjurin 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ninj1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ninj1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NINJ1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NINJ1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ninj1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NINJ1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NINJ1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ninj1 (ninjurin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ninj1 (ninjurin 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NINJ1 (ninjurin 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch1073-278o19.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	NijA	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	NijB	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER)
Drosophila melanogaster (fruit fly):	NijC	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ninj1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	15,659,208 - 15,668,115 (-)	NCBI		GRCr8
mRatBN7.2	17	15,452,804 - 15,461,684 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	15,452,813 - 15,461,704 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	15,339,900 - 15,348,710 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	16,944,942 - 16,953,752 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	15,266,672 - 15,275,482 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	15,866,235 - 15,881,284 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,866,237 - 15,881,327 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	17,930,052 - 17,945,126 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	21,410,701 - 21,419,472 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	21,410,700 - 21,419,472 (-)	NCBI
Celera	17	15,182,635 - 15,191,450 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

RGD Manual Disease Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	COVID-19		ISO	RGD:737046	9068941	mRNA:increased expression:bronchoalveolar lavage (human)	RGD	PMID:32407669\|REF_RGD_ID:30296672

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	allergic contact dermatitis		ISO	RGD:737046	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17374397

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	(-)-demecolcine	increases expression	ISO	RGD:737046	6480464	Demecolcine results in increased expression of NINJ1 mRNA	CTD	PMID:23649840
Ninj1	Rat	1,4-phenylenediamine	increases expression	ISO	RGD:737046	6480464	4-phenylenediamine results in increased expression of NINJ1 mRNA	CTD	PMID:16314067
Ninj1	Rat	1-chloro-2,4-dinitrobenzene	increases expression	ISO	RGD:737046	6480464	Dinitrochlorobenzene results in increased expression of NINJ1 mRNA	CTD	PMID:16314067\|PMID:17374397
Ninj1	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	RGD:10985	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NINJ1 mRNA	CTD	PMID:17942748
Ninj1	Rat	17beta-estradiol	multiple interactions	ISO	RGD:737046	6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of NINJ1 mRNA	CTD	PMID:30165855
Ninj1	Rat	2,2'-Methylenebis(4-methyl-6-tert-butylphenol)	multiple interactions	ISO	RGD:737046	6480464	[CYP3A4 protein affects the susceptibility to 2,2'-methylenebis(4-methyl-6-tert-butylphenol)] which affects the expression of NINJ1 mRNA	CTD	PMID:38160208
Ninj1	Rat	2,3',4,4',5-Pentachlorobiphenyl	decreases expression	ISO	RGD:10985	6480464	2,3',4,4',5-pentachlorobiphenyl results in decreased expression of NINJ1 mRNA	CTD	PMID:31388691
Ninj1	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:10985	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NINJ1 mRNA	CTD	PMID:17942748
Ninj1	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of NINJ1 mRNA	CTD	PMID:33387578
Ninj1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of NINJ1 mRNA	CTD	PMID:34747641
Ninj1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:10985	6480464	Tetrachlorodibenzodioxin affects the expression of NINJ1 mRNA	CTD	PMID:21570461
Ninj1	Rat	2-acetamidofluorene	multiple interactions	EXP		6480464	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] more ...	CTD	PMID:14656948\|PMID:16158176
Ninj1	Rat	2-hydroxypropanoic acid	increases expression	ISO	RGD:737046	6480464	Lactic Acid results in increased expression of NINJ1 mRNA	CTD	PMID:30851411
Ninj1	Rat	2-methoxyethanol	increases expression	EXP		6480464	methyl cellosolve results in increased expression of NINJ1 mRNA	CTD	PMID:21061450
Ninj1	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	RGD:10985	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of NINJ1 mRNA	CTD	PMID:20188158
Ninj1	Rat	3,4-methylenedioxymethamphetamine	increases expression	EXP		6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of NINJ1 mRNA	CTD	PMID:30071829
Ninj1	Rat	4-(ethoxymethylene)-2-phenyloxazol-5-one	increases expression	ISO	RGD:737046	6480464	Oxazolone results in increased expression of NINJ1 mRNA	CTD	PMID:17374397
Ninj1	Rat	5-fluorouracil	multiple interactions	ISO	RGD:737046	6480464	TP53 protein affects the reaction [Fluorouracil results in increased expression of NINJ1 mRNA]	CTD	PMID:15016801
Ninj1	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of NINJ1 mRNA	CTD	PMID:24780913\|PMID:30047161
Ninj1	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of NINJ1 mRNA	CTD	PMID:36843608
Ninj1	Rat	acetylsalicylic acid	decreases expression	ISO	RGD:737046	6480464	Aspirin results in decreased expression of NINJ1 mRNA	CTD	PMID:15928584
Ninj1	Rat	actinomycin D	multiple interactions	ISO	RGD:737046	6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of NINJ1 mRNA	CTD	PMID:38460933
Ninj1	Rat	adefovir pivoxil	increases expression	ISO	RGD:737046	6480464	adefovir dipivoxil results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	all-trans-retinoic acid	increases expression	ISO	RGD:737046	6480464	Tretinoin results in increased expression of NINJ1 mRNA	CTD	PMID:12875902\|PMID:33167477
Ninj1	Rat	all-trans-retinoic acid	multiple interactions	ISO	RGD:737046	6480464	[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNA	CTD	PMID:16443354
Ninj1	Rat	amitrole	increases expression	EXP		6480464	Amitrole results in increased expression of NINJ1 mRNA	CTD	PMID:30047161
Ninj1	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of NINJ1 mRNA	CTD	PMID:16483693
Ninj1	Rat	arsane	decreases expression	ISO	RGD:737046	6480464	Arsenic results in decreased expression of NINJ1 mRNA	CTD	PMID:27838757
Ninj1	Rat	arsenic atom	decreases expression	ISO	RGD:737046	6480464	Arsenic results in decreased expression of NINJ1 mRNA	CTD	PMID:27838757
Ninj1	Rat	benzo[a]pyrene	increases expression	ISO	RGD:10985	6480464	Benzo(a)pyrene results in increased expression of NINJ1 mRNA	CTD	PMID:21569818\|PMID:22228805
Ninj1	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:737046	6480464	Benzo(a)pyrene affects the methylation of NINJ1 promoter	CTD	PMID:27901495
Ninj1	Rat	benzo[e]pyrene	increases methylation	ISO	RGD:737046	6480464	benzo(e)pyrene results in increased methylation of NINJ1 intron	CTD	PMID:30157460
Ninj1	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:10985	6480464	Diethylhexyl Phthalate results in increased expression of NINJ1 mRNA	CTD	PMID:33162236
Ninj1	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:10985	6480464	Diethylhexyl Phthalate results in decreased expression of NINJ1 mRNA	CTD	PMID:34319233
Ninj1	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of NINJ1 mRNA	CTD	PMID:25181051
Ninj1	Rat	bisphenol A	increases expression	ISO	RGD:10985	6480464	bisphenol A results in increased expression of NINJ1 mRNA	CTD	PMID:32156529
Ninj1	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of NINJ1 mRNA	CTD	PMID:34947998
Ninj1	Rat	bisphenol A	affects expression	ISO	RGD:737046	6480464	bisphenol A affects the expression of NINJ1 mRNA	CTD	PMID:30903817
Ninj1	Rat	cadmium dichloride	affects expression	EXP		6480464	Cadmium Chloride affects the expression of NINJ1 mRNA	CTD	PMID:22110744
Ninj1	Rat	cadmium dichloride	affects expression	ISO	RGD:737046	6480464	Cadmium Chloride affects the expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	calcitriol	increases expression	ISO	RGD:737046	6480464	Calcitriol results in increased expression of NINJ1 mRNA	CTD	PMID:12875902
Ninj1	Rat	camptothecin	increases expression	ISO	RGD:737046	6480464	Camptothecin results in increased expression of NINJ1 mRNA	CTD	PMID:38460933
Ninj1	Rat	carbon nanotube	increases expression	ISO	RGD:10985	6480464	Nanotubes, Carbon analog results in increased expression of NINJ1 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
Ninj1	Rat	carbon nanotube	decreases expression	ISO	RGD:10985	6480464	Nanotubes, Carbon results in decreased expression of NINJ1 mRNA	CTD	PMID:25620056
Ninj1	Rat	chloroacetaldehyde	increases expression	ISO	RGD:737046	6480464	chloroacetaldehyde results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	chlorpromazine	increases expression	EXP		6480464	Chlorpromazine results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	chlorpyrifos	increases expression	EXP		6480464	Chlorpyrifos results in increased expression of NINJ1 mRNA	CTD	PMID:18668222
Ninj1	Rat	cidofovir anhydrous	increases expression	ISO	RGD:737046	6480464	Cidofovir results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	cisplatin	increases expression	ISO	RGD:737046	6480464	Cisplatin results in increased expression of NINJ1 mRNA	CTD	PMID:21532991\|PMID:25596134\|PMID:27392435\|PMID:27594783
Ninj1	Rat	cisplatin	multiple interactions	ISO	RGD:737046	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of NINJ1 mRNA	CTD	PMID:27392435
Ninj1	Rat	clobetasol	increases expression	ISO	RGD:10985	6480464	Clobetasol results in increased expression of NINJ1 mRNA	CTD	PMID:27462272
Ninj1	Rat	clofibrate	decreases expression	ISO	RGD:10985	6480464	Clofibrate results in decreased expression of NINJ1 mRNA	CTD	PMID:17585979
Ninj1	Rat	copper(II) sulfate	decreases expression	ISO	RGD:737046	6480464	Copper Sulfate results in decreased expression of NINJ1 mRNA	CTD	PMID:19549813
Ninj1	Rat	cyclosporin A	increases expression	EXP		6480464	Cyclosporine results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	cyclosporin A	decreases expression	ISO	RGD:737046	6480464	Cyclosporine results in decreased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	DDE	decreases expression	ISO	RGD:737046	6480464	Dichlorodiphenyl Dichloroethylene results in decreased expression of NINJ1 mRNA	CTD	PMID:38568856
Ninj1	Rat	diazinon	increases methylation	ISO	RGD:737046	6480464	Diazinon results in increased methylation of NINJ1 gene	CTD	PMID:22964155
Ninj1	Rat	Dibutyl phosphate	affects expression	ISO	RGD:737046	6480464	di-n-butylphosphoric acid affects the expression of NINJ1 mRNA	CTD	PMID:37042841
Ninj1	Rat	dibutyl phthalate	increases expression	EXP		6480464	Dibutyl Phthalate results in increased expression of NINJ1 mRNA	CTD	PMID:21266533
Ninj1	Rat	dicyclanil	increases expression	ISO	RGD:10985	6480464	dicyclanil results in increased expression of NINJ1 mRNA	CTD	PMID:15664270
Ninj1	Rat	diethylstilbestrol	increases expression	EXP		6480464	Diethylstilbestrol results in increased expression of NINJ1 mRNA	CTD	PMID:17005392
Ninj1	Rat	diethylstilbestrol	increases expression	ISO	RGD:737046	6480464	Diethylstilbestrol results in increased expression of NINJ1 mRNA	CTD	PMID:36621641
Ninj1	Rat	dimethylarsinic acid	increases expression	EXP		6480464	Cacodylic Acid results in increased expression of NINJ1 mRNA	CTD	PMID:16122865
Ninj1	Rat	dioxygen	decreases expression	ISO	RGD:737046	6480464	Oxygen deficiency results in decreased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	disodium selenite	increases expression	ISO	RGD:737046	6480464	Sodium Selenite results in increased expression of NINJ1 mRNA	CTD	PMID:24383545
Ninj1	Rat	diuron	increases expression	EXP		6480464	Diuron results in increased expression of NINJ1 mRNA	CTD	PMID:21551480
Ninj1	Rat	doxorubicin	decreases expression	ISO	RGD:737046	6480464	Doxorubicin results in decreased expression of NINJ1 mRNA	CTD	PMID:29803840
Ninj1	Rat	elemental selenium	increases expression	ISO	RGD:737046	6480464	Selenium results in increased expression of NINJ1 mRNA	CTD	PMID:19244175
Ninj1	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of NINJ1 mRNA	CTD	PMID:29391264
Ninj1	Rat	ethyl methanesulfonate	increases expression	ISO	RGD:737046	6480464	Ethyl Methanesulfonate results in increased expression of NINJ1 mRNA	CTD	PMID:23649840
Ninj1	Rat	fenofibrate	affects expression	EXP		6480464	Fenofibrate affects the expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of NINJ1 mRNA	CTD	PMID:24136188
Ninj1	Rat	formaldehyde	increases expression	ISO	RGD:737046	6480464	Formaldehyde results in increased expression of NINJ1 mRNA	CTD	PMID:23649840
Ninj1	Rat	genistein	increases expression	ISO	RGD:737046	6480464	Genistein results in increased expression of NINJ1 mRNA	CTD	PMID:18847459
Ninj1	Rat	glafenine	increases expression	EXP		6480464	Glafenine results in increased expression of NINJ1 mRNA	CTD	PMID:24136188
Ninj1	Rat	isoprenaline	increases expression	ISO	RGD:10985	6480464	Isoproterenol results in increased expression of NINJ1 mRNA	CTD	PMID:20003209
Ninj1	Rat	ketoconazole	increases expression	ISO	RGD:737046	6480464	Ketoconazole results in increased expression of NINJ1 mRNA	CTD	PMID:36621641
Ninj1	Rat	L-ascorbic acid	multiple interactions	ISO	RGD:737046	6480464	[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNA	CTD	PMID:16443354
Ninj1	Rat	lead(0)	affects expression	ISO	RGD:737046	6480464	Lead affects the expression of NINJ1 mRNA	CTD	PMID:28903495
Ninj1	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:737046	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of NINJ1 mRNA	CTD	PMID:35811015
Ninj1	Rat	lipopolysaccharide	increases expression	ISO	RGD:737046	6480464	Lipopolysaccharides results in increased expression of NINJ1 mRNA	CTD	PMID:35811015
Ninj1	Rat	malathion	decreases expression	ISO	RGD:737046	6480464	Malathion results in decreased expression of NINJ1 mRNA	CTD	PMID:32069766
Ninj1	Rat	metformin	increases expression	EXP		6480464	Metformin results in increased expression of NINJ1 mRNA	CTD	PMID:25596134
Ninj1	Rat	methapyrilene	increases methylation	ISO	RGD:737046	6480464	Methapyrilene results in increased methylation of NINJ1 intron	CTD	PMID:30157460
Ninj1	Rat	methapyrilene	increases expression	EXP		6480464	Methapyrilene results in increased expression of NINJ1 mRNA	CTD	PMID:30467583
Ninj1	Rat	methimazole	increases expression	EXP		6480464	Methimazole results in increased expression of NINJ1 mRNA	CTD	PMID:30047161
Ninj1	Rat	methyl methanesulfonate	increases expression	ISO	RGD:737046	6480464	Methyl Methanesulfonate results in increased expression of NINJ1 mRNA	CTD	PMID:23649840
Ninj1	Rat	morphine	increases expression	ISO	RGD:737046	6480464	Morphine results in increased expression of NINJ1 mRNA	CTD	PMID:19397953
Ninj1	Rat	N-methyl-4-phenylpyridinium	increases expression	ISO	RGD:10985	6480464	1-Methyl-4-phenylpyridinium results in increased expression of NINJ1 mRNA	CTD	PMID:22776087
Ninj1	Rat	N-methyl-4-phenylpyridinium	increases expression	ISO	RGD:737046	6480464	1-Methyl-4-phenylpyridinium results in increased expression of NINJ1 mRNA	CTD	PMID:24810058
Ninj1	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] more ...	CTD	PMID:14656948\|PMID:16158176
Ninj1	Rat	nickel atom	increases expression	ISO	RGD:737046	6480464	Nickel results in increased expression of NINJ1 mRNA	CTD	PMID:23195993
Ninj1	Rat	nickel sulfate	increases expression	ISO	RGD:737046	6480464	nickel sulfate results in increased expression of NINJ1 mRNA	CTD	PMID:16314067\|PMID:16780908\|PMID:17374397\|PMID:22714537
Ninj1	Rat	nitrates	multiple interactions	ISO	RGD:10985	6480464	[Particulate Matter results in increased abundance of Nitrates] which results in increased expression of NINJ1 more ...	CTD	PMID:35964746
Ninj1	Rat	Nutlin-3	multiple interactions	ISO	RGD:737046	6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of NINJ1 mRNA	CTD	PMID:38460933
Ninj1	Rat	organophosphorus compound	multiple interactions	EXP		6480464	[Dust results in increased abundance of Organophosphorus Compounds] which results in decreased expression of NINJ1 more ...	CTD	PMID:39658253
Ninj1	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of NINJ1 mRNA	CTD	PMID:25729387
Ninj1	Rat	ozone	decreases expression	ISO	RGD:10985	6480464	Ozone results in decreased expression of NINJ1 mRNA	CTD	PMID:12763052
Ninj1	Rat	paracetamol	affects expression	ISO	RGD:737046	6480464	Acetaminophen affects the expression of NINJ1 mRNA	CTD	PMID:25458485
Ninj1	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of NINJ1 mRNA	CTD	PMID:33387578
Ninj1	Rat	paraquat	increases expression	EXP		6480464	Paraquat results in increased expression of NINJ1 mRNA	CTD	PMID:32680482
Ninj1	Rat	pentachlorophenol	increases expression	ISO	RGD:10985	6480464	Pentachlorophenol results in increased expression of NINJ1 mRNA	CTD	PMID:23892564
Ninj1	Rat	pinostrobin	increases expression	ISO	RGD:737046	6480464	pinostrobin results in increased expression of NINJ1 mRNA	CTD	PMID:37777166
Ninj1	Rat	propiconazole	increases expression	EXP		6480464	propiconazole results in increased expression of NINJ1 mRNA	CTD	PMID:30047161
Ninj1	Rat	rac-lactic acid	increases expression	ISO	RGD:737046	6480464	Lactic Acid results in increased expression of NINJ1 mRNA	CTD	PMID:30851411
Ninj1	Rat	raloxifene	multiple interactions	ISO	RGD:737046	6480464	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA	CTD	PMID:19059307
Ninj1	Rat	rotenone	increases expression	ISO	RGD:737046	6480464	Rotenone results in increased expression of NINJ1 mRNA	CTD	PMID:29955902
Ninj1	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	RGD:737046	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of NINJ1 mRNA	CTD	PMID:35811015
Ninj1	Rat	selenium atom	increases expression	ISO	RGD:737046	6480464	Selenium results in increased expression of NINJ1 mRNA	CTD	PMID:19244175
Ninj1	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of NINJ1 mRNA	CTD	PMID:19281266
Ninj1	Rat	succimer	multiple interactions	ISO	RGD:10985	6480464	[Succimer binds to Magnetite Nanoparticles] which results in increased expression of NINJ1 mRNA	CTD	PMID:21641980
Ninj1	Rat	sulfadimethoxine	increases expression	EXP		6480464	Sulfadimethoxine results in increased expression of NINJ1 mRNA	CTD	PMID:30047161
Ninj1	Rat	sunitinib	increases expression	ISO	RGD:737046	6480464	Sunitinib results in increased expression of NINJ1 mRNA	CTD	PMID:31533062
Ninj1	Rat	tamoxifen	multiple interactions	ISO	RGD:737046	6480464	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA	CTD	PMID:19059307
Ninj1	Rat	temozolomide	decreases expression	ISO	RGD:737046	6480464	Temozolomide results in decreased expression of NINJ1 mRNA	CTD	PMID:31758290
Ninj1	Rat	testosterone	decreases expression	ISO	RGD:737046	6480464	Testosterone results in decreased expression of NINJ1 mRNA	CTD	PMID:33359661
Ninj1	Rat	thiram	decreases expression	ISO	RGD:737046	6480464	Thiram results in decreased expression of NINJ1 mRNA	CTD	PMID:38568856
Ninj1	Rat	titanium dioxide	increases methylation	ISO	RGD:10985	6480464	titanium dioxide results in increased methylation of NINJ1 gene	CTD	PMID:35295148
Ninj1	Rat	titanium dioxide	decreases methylation	ISO	RGD:10985	6480464	titanium dioxide results in decreased methylation of NINJ1 gene	CTD	PMID:35295148
Ninj1	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of NINJ1 mRNA	CTD	PMID:25729387
Ninj1	Rat	topotecan	increases expression	EXP		6480464	Topotecan results in increased expression of NINJ1 mRNA	CTD	PMID:25729387
Ninj1	Rat	trichloroethene	increases methylation	EXP		6480464	Trichloroethylene results in increased methylation of NINJ1 gene	CTD	PMID:27618143
Ninj1	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of NINJ1 mRNA	CTD	PMID:33387578
Ninj1	Rat	triphenyl phosphate	affects expression	ISO	RGD:737046	6480464	triphenyl phosphate affects the expression of NINJ1 mRNA	CTD	PMID:37042841
Ninj1	Rat	tunicamycin	increases expression	ISO	RGD:737046	6480464	Tunicamycin results in increased expression of NINJ1 mRNA	CTD	PMID:22378314
Ninj1	Rat	valproic acid	affects expression	ISO	RGD:737046	6480464	Valproic Acid affects the expression of NINJ1 mRNA	CTD	PMID:25979313
Ninj1	Rat	valproic acid	decreases expression	ISO	RGD:737046	6480464	Valproic Acid results in decreased expression of NINJ1 mRNA	CTD	PMID:29154799
Ninj1	Rat	valproic acid	increases methylation	ISO	RGD:737046	6480464	Valproic Acid results in increased methylation of NINJ1 gene	CTD	PMID:29154799
Ninj1	Rat	vinclozolin	decreases expression	EXP		6480464	vinclozolin results in decreased expression of NINJ1 mRNA	CTD	PMID:23034163
Ninj1	Rat	vincristine	increases expression	ISO	RGD:737046	6480464	Vincristine results in increased expression of NINJ1 mRNA	CTD	PMID:23649840
Ninj1	Rat	zoledronic acid	decreases expression	ISO	RGD:737046	6480464	zoledronic acid results in decreased expression of NINJ1 mRNA	CTD	PMID:25596134

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	angiogenesis	involved_in	IEA	UniProtKB-KW:KW-0037	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	cell adhesion	involved_in	ISO	RGD:737046	1624291	PMID:33028854	RGD	PMID:33028854
Ninj1	Rat	cell adhesion	involved_in	IEA	UniProtKB-KW:KW-0130	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	cell adhesion	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	cell adhesion	involved_in	ISO	RGD:10985	1624291	PMID:24347169, PMID:24917672	RGD	PMID:24347169\|PMID:24917672
Ninj1	Rat	cell adhesion	involved_in	IBA	FB:FBgn0036101\|MGI:1196617\|PANTHER:PTN000960117\|RGD:3179\|UniProtKB:Q92982	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ninj1	Rat	cell adhesion	involved_in	IEA	InterPro:IPR007007	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ninj1	Rat	cell adhesion	involved_in	IDA		126781729	PMID:33028854	UniProt
Ninj1	Rat	cellular hyperosmotic response	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	cellular hyperosmotic response	involved_in	ISO	RGD:10985	1624291	PMID:37980412	RGD	PMID:37980412
Ninj1	Rat	chemotaxis	involved_in	ISO	RGD:10985,UniProtKB:O70131-PRO_0000452825	1624291	PMID:23142597	RGD	PMID:23142597
Ninj1	Rat	cytolysis	involved_in	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	cytolysis	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	cytolysis	involved_in	ISO	RGD:737046	1624291	PMID:33472215, PMID:38614101, PMID:39667936	RGD	PMID:33472215\|PMID:38614101\|PMID:39667936
Ninj1	Rat	cytolysis	involved_in	ISO	RGD:10985	1624291	PMID:33472215, PMID:37980412, PMID:38396301, PMID:39476863	RGD	PMID:33472215\|PMID:37980412\|PMID:38396301\|PMID:39476863
Ninj1	Rat	cytolysis	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	ferroptosis	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	ferroptosis	involved_in	ISO	RGD:10985	1624291	PMID:38396301	RGD	PMID:38396301
Ninj1	Rat	heterotypic cell-cell adhesion	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	heterotypic cell-cell adhesion	involved_in	ISO	RGD:10985	1624291	PMID:25766274	RGD	PMID:25766274
Ninj1	Rat	hyaloid vascular plexus regression	acts_upstream_of_or_within	ISO	RGD:10985	1624291	PMID:19557008	RGD	PMID:19557008
Ninj1	Rat	inflammatory response	involved_in	ISS	UniProtKB:Q92982-PRO_0000452824	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	inflammatory response	involved_in	IEA	UniProtKB-KW:KW-0395	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	inflammatory response	involved_in	ISO	RGD:10985	1624291	PMID:24347169	RGD	PMID:24347169
Ninj1	Rat	inflammatory response	involved_in	ISO	RGD:10985,UniProtKB:O70131-PRO_0000452825	1624291	PMID:32883094	RGD	PMID:32883094
Ninj1	Rat	inflammatory response	involved_in	ISO	RGD:737046,UniProtKB:Q92982-PRO_0000452824	1624291	PMID:32883094	RGD	PMID:32883094
Ninj1	Rat	killing of cells of another organism	involved_in	IEA	UniProtKB-KW:KW-0204	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	leukocyte chemotaxis involved in inflammatory response	involved_in	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	leukocyte chemotaxis involved in inflammatory response	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	leukocyte chemotaxis involved in inflammatory response	involved_in	ISO	RGD:10985	1624291	PMID:24917672, PMID:30510259	RGD	PMID:24917672\|PMID:30510259
Ninj1	Rat	leukocyte chemotaxis involved in inflammatory response	involved_in	ISO	RGD:737046	1624291	PMID:22162058	RGD	PMID:22162058
Ninj1	Rat	macrophage chemotaxis	involved_in	ISO	RGD:10985	1624291	PMID:24917672	RGD	PMID:24917672
Ninj1	Rat	muscle cell differentiation	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	muscle cell differentiation	involved_in	ISO	RGD:10985	1624291	PMID:31091274	RGD	PMID:31091274
Ninj1	Rat	pericyte cell migration	involved_in	ISO	RGD:10985	1624291	PMID:25766274	RGD	PMID:25766274
Ninj1	Rat	positive regulation of angiogenesis	involved_in	ISO	RGD:737046	1624291	PMID:33028854	RGD	PMID:33028854
Ninj1	Rat	positive regulation of angiogenesis	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	positive regulation of angiogenesis	involved_in	IDA		126781729	PMID:33028854	UniProt
Ninj1	Rat	positive regulation of cell-matrix adhesion	acts_upstream_of_or_within	ISO	RGD:10985	1624291	PMID:19557008	RGD	PMID:19557008
Ninj1	Rat	positive regulation of inflammatory response	involved_in	ISO	RGD:10985	1624291	PMID:26677008	RGD	PMID:26677008
Ninj1	Rat	positive regulation of inflammatory response	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	positive regulation of inflammatory response	involved_in	ISO	RGD:737046	1624291	PMID:26677008	RGD	PMID:26677008
Ninj1	Rat	positive regulation of inflammatory response	involved_in	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	positive regulation of osteoclast development	involved_in	ISO	RGD:10985	1624291	PMID:30700695	RGD	PMID:30700695
Ninj1	Rat	positive regulation of toll-like receptor 4 signaling pathway	involved_in	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	positive regulation of toll-like receptor 4 signaling pathway	involved_in	ISO	RGD:10985	1624291	PMID:25860173	RGD	PMID:25860173
Ninj1	Rat	programmed necrotic cell death	involved_in	ISO	RGD:737046	1624291	PMID:33472215	RGD	PMID:33472215
Ninj1	Rat	programmed necrotic cell death	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	programmed necrotic cell death	involved_in	ISO	RGD:10985	1624291	PMID:37980412	RGD	PMID:37980412
Ninj1	Rat	protein homooligomerization	involved_in	ISO	RGD:737046	1624291	PMID:33472215, PMID:37196676, PMID:37198476, PMID:38396301, PMID:38614101	RGD	PMID:33472215\|PMID:37196676\|PMID:37198476\|PMID:38396301\|PMID:38614101
Ninj1	Rat	protein homooligomerization	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	protein homooligomerization	involved_in	ISO	RGD:10985	1624291	PMID:24917672, PMID:33472215, PMID:38396301	RGD	PMID:24917672\|PMID:33472215\|PMID:38396301
Ninj1	Rat	pyroptotic cell death	involved_in	ISO	RGD:737046	1624291	PMID:36468682, PMID:37196676, PMID:37198476, PMID:38614101	RGD	PMID:36468682\|PMID:37196676\|PMID:37198476\|PMID:38614101
Ninj1	Rat	pyroptotic cell death	involved_in	ISO	RGD:10985	1624291	PMID:36468682, PMID:37196676, PMID:37198476	RGD	PMID:36468682\|PMID:37196676\|PMID:37198476
Ninj1	Rat	pyroptotic cell death	involved_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	regulation of angiogenesis	involved_in	ISO	RGD:10985	1624291	PMID:25766274	RGD	PMID:25766274
Ninj1	Rat	regulation of monocyte chemotaxis	involved_in	ISO	RGD:10985,UniProtKB:O70131-PRO_0000452825	1624291	PMID:32883094	RGD	PMID:32883094
Ninj1	Rat	regulation of monocyte chemotaxis	involved_in	ISS	UniProtKB:Q92982-PRO_0000452824	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	regulation of monocyte chemotaxis	involved_in	ISO	RGD:737046,UniProtKB:Q92982-PRO_0000452824	1624291	PMID:32883094	RGD	PMID:32883094
Ninj1	Rat	tissue regeneration	involved_in	IEA	InterPro:IPR007007	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	extracellular region	is_active_in	ISO	RGD:737046,UniProtKB:Q92982-PRO_0000452824	1624291	PMID:32883094	RGD	PMID:32883094
Ninj1	Rat	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ninj1	Rat	extracellular region	located_in	ISO	RGD:10985,UniProtKB:O70131-PRO_0000452825	1624291	PMID:23142597, PMID:32883094	RGD	PMID:23142597\|PMID:32883094
Ninj1	Rat	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	extracellular region	is_active_in	ISS	UniProtKB:Q92982-PRO_0000452824	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	filopodium membrane	located_in	ISO	RGD:10985	1624291	PMID:24917672	RGD	PMID:24917672
Ninj1	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	membrane	located_in	IEA	InterPro:IPR007007	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ninj1	Rat	plasma membrane	is_active_in	ISO	RGD:10985	1624291	PMID:38396301	RGD	PMID:38396301
Ninj1	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ninj1	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	plasma membrane	is_active_in	ISO	RGD:737046	1624291	PMID:37198476, PMID:38396301, PMID:38614101, PMID:39667936	RGD	PMID:37198476\|PMID:38396301\|PMID:38614101\|PMID:39667936
Ninj1	Rat	plasma membrane	located_in	ISO	RGD:10985	1624291	PMID:27815839, PMID:31091274, PMID:33472215	RGD	PMID:27815839\|PMID:31091274\|PMID:33472215
Ninj1	Rat	plasma membrane	is_active_in	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	plasma membrane	is_active_in	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	synapse	located_in	IEA	UniProtKB-KW:KW-0770	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ninj1	Rat	synaptic membrane	located_in	ISO	RGD:10985	1624291	PMID:27815839	RGD	PMID:27815839
Ninj1	Rat	synaptic membrane	located_in	IEA	UniProtKB-SubCell:SL-0531	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ninj1	Rat	cell adhesion mediator activity	enables	ISO	RGD:737046	1624291	PMID:33028854	RGD	PMID:33028854
Ninj1	Rat	cell adhesion mediator activity	enables	ISO	RGD:10985	1624291	PMID:24347169, PMID:24917672	RGD	PMID:24347169\|PMID:24917672
Ninj1	Rat	cell adhesion mediator activity	enables	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	cell adhesion mediator activity	enables	IDA		126781729	PMID:33028854	UniProt
Ninj1	Rat	cell-cell adhesion mediator activity	enables	ISO	RGD:10985	1624291	PMID:25766274	RGD	PMID:25766274
Ninj1	Rat	lipopolysaccharide binding	enables	ISO	RGD:737046	1624291	PMID:26677008	RGD	PMID:26677008
Ninj1	Rat	lipopolysaccharide binding	enables	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	lipopolysaccharide binding	enables	ISO	RGD:10985	1624291	PMID:26677008	RGD	PMID:26677008
Ninj1	Rat	lipopolysaccharide binding	enables	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	membrane destabilizing activity	enables	ISS	UniProtKB:O70131	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	membrane destabilizing activity	enables	ISO	RGD:737046	1624291	PMID:33472215, PMID:36468682, PMID:37196676, PMID:37198476, PMID:38614101, PMID:39667936	RGD	PMID:33472215\|PMID:36468682\|PMID:37196676\|PMID:37198476\|PMID:38614101\|PMID:39667936
Ninj1	Rat	membrane destabilizing activity	enables	ISO	RGD:10985	1624291	PMID:33472215, PMID:36468682, PMID:37196676, PMID:37198476, PMID:37980412, PMID:39476863	RGD	PMID:33472215\|PMID:36468682\|PMID:37196676\|PMID:37198476\|PMID:37980412\|PMID:39476863
Ninj1	Rat	membrane destabilizing activity	enables	IEA	UniProtKB:Q92982\|ensembl:ENSP00000364595	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ninj1	Rat	membrane destabilizing activity	enables	ISS	UniProtKB:Q92982	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Ninj1	Rat	protein binding	enables	ISO	RGD:737046	1624291	UniProtKB:P00387\|UniProtKB:P12314\|UniProtKB:P15151\|UniProtKB:P15941-11\|UniProtKB:P40198\|UniProtKB:Q13520\|UniProtKB:Q15125\|UniProtKB:Q16585\|UniProtKB:Q6A162\|UniProtKB:Q8NBJ4\|UniProtKB:Q8TBE3\|UniProtKB:Q8TD46-4\|UniProtKB:Q8TED1\|UniProtKB:Q96BA8\|UniProtKB:Q96MV1\|UniProtKB:Q9H400\|UniProtKB:Q9NPL8\|UniProtKB:Q9NUH8 PMID:25416956, PMID:32296183	RGD	PMID:25416956\|PMID:32296183

Disease Annotations Click to see Annotation Detail View

allergic contact dermatitis (ISO)

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,4-phenylenediamine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-acetamidofluorene (EXP)

2-hydroxypropanoic acid (ISO)

2-methoxyethanol (EXP)

3,4-methylenedioxymethamphetamine (EXP,ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetylsalicylic acid (ISO)

actinomycin D (ISO)

adefovir pivoxil (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

chlorpromazine (EXP)

chlorpyrifos (EXP)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

cyclosporin A (EXP,ISO)

DDE (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dicyclanil (ISO)

diethylstilbestrol (EXP,ISO)

dimethylarsinic acid (EXP)

dioxygen (ISO)

disodium selenite (ISO)

diuron (EXP)

doxorubicin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

ethyl methanesulfonate (ISO)

fenofibrate (EXP)

flutamide (EXP)

formaldehyde (ISO)

genistein (ISO)

glafenine (EXP)

isoprenaline (ISO)

ketoconazole (ISO)

L-ascorbic acid (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

malathion (ISO)

metformin (EXP)

methapyrilene (EXP,ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

morphine (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

nitrates (ISO)

Nutlin-3 (ISO)

organophosphorus compound (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

pentachlorophenol (ISO)

pinostrobin (ISO)

propiconazole (EXP)

rac-lactic acid (ISO)

raloxifene (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

selenium atom (ISO)

Soman (EXP)

succimer (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

triphenyl phosphate (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

cell adhesion (IBA,IDA,IEA,ISO)

cellular hyperosmotic response (ISO,ISS)

chemotaxis (ISO)

cytolysis (IEA,ISO,ISS)

ferroptosis (ISO,ISS)

heterotypic cell-cell adhesion (ISO,ISS)

hyaloid vascular plexus regression (ISO)

inflammatory response (IEA,ISO,ISS)

killing of cells of another organism (IEA)

leukocyte chemotaxis involved in inflammatory response (IEA,ISO,ISS)

macrophage chemotaxis (ISO)

muscle cell differentiation (ISO,ISS)

pericyte cell migration (ISO)

positive regulation of angiogenesis (IDA,IEA,ISO)

positive regulation of cell-matrix adhesion (ISO)

positive regulation of inflammatory response (IEA,ISO,ISS)

positive regulation of osteoclast development (ISO)

positive regulation of toll-like receptor 4 signaling pathway (ISO,ISS)

programmed necrotic cell death (IEA,ISO)

protein homooligomerization (IEA,ISO)

pyroptotic cell death (IEA,ISO)

regulation of angiogenesis (ISO)

regulation of monocyte chemotaxis (ISO,ISS)

tissue regeneration (IEA)

Cellular Component

extracellular region (IEA,ISO,ISS)

filopodium membrane (ISO)

membrane (IEA)

plasma membrane (IEA,ISO,ISS)

synapse (IEA)

synaptic membrane (IEA,ISO)

Molecular Function

cell adhesion mediator activity (IDA,IEA,ISO)

cell-cell adhesion mediator activity (ISO)

lipopolysaccharide binding (IEA,ISO,ISS)

membrane destabilizing activity (IEA,ISO,ISS)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth.	Araki T and Milbrandt J, Neuron 1996 Aug;17(2):353-61.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Ninjurin 1 dodecamer peptide containing the N-terminal adhesion motif (N-NAM) exerts proangiogenic effects in HUVECs and in the postischemic brain.	Kim SW, etal., Sci Rep. 2020 Oct 7;10(1):16656. doi: 10.1038/s41598-020-73340-5.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:19557008	PMID:19595672	PMID:33472215

Genomics

Comparative Map Data

Ninj1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	15,659,208 - 15,668,115 (-)	NCBI		GRCr8
mRatBN7.2	17	15,452,804 - 15,461,684 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	15,452,813 - 15,461,704 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	15,339,900 - 15,348,710 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	16,944,942 - 16,953,752 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	15,266,672 - 15,275,482 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	15,866,235 - 15,881,284 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,866,237 - 15,881,327 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	17,930,052 - 17,945,126 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	21,410,701 - 21,419,472 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	21,410,700 - 21,419,472 (-)	NCBI
Celera	17	15,182,635 - 15,191,450 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

NINJ1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	93,121,496 - 93,134,251 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	93,121,496 - 93,134,251 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	95,883,778 - 95,896,533 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	94,923,592 - 94,936,391 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	92,963,334 - 92,976,125	NCBI
Celera	9	66,325,478 - 66,338,278 (-)	NCBI		Celera
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	65,560,157 - 65,572,990 (-)	NCBI		HuRef
CHM1_1	9	96,030,378 - 96,043,177 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	105,288,107 - 105,300,864 (-)	NCBI		T2T-CHM13v2.0

Ninj1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	49,341,005 - 49,349,727 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	49,340,961 - 49,349,720 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	49,187,529 - 49,196,251 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	49,187,485 - 49,196,244 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	49,282,916 - 49,291,620 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	49,199,484 - 49,208,188 (+)	NCBI		MGSCv36	mm8
Celera	13	50,277,705 - 50,286,409 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	25.14	NCBI

Ninj1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	4,892,039 - 4,907,323 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955515	4,892,748 - 4,905,627 (+)	NCBI	ChiLan1.0	ChiLan1.0

NINJ1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	46,293,062 - 46,306,329 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	46,295,457 - 46,308,713 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	64,245,086 - 64,258,614 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	92,311,502 - 92,324,025 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	92,311,502 - 92,324,030 (-)	Ensembl	panpan1.1		panPan2

NINJ1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	98,566,520 - 98,576,668 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	98,567,680 - 98,576,657 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	98,960,941 - 98,970,738 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	99,183,728 - 99,193,686 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	1	98,797,064 - 98,806,858 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	98,532,406 - 98,542,206 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	99,288,008 - 99,297,814 (+)	NCBI		UU_Cfam_GSD_1.0

Ninj1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	8,270,364 - 8,275,943 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	2,487,904 - 2,491,827 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	2,486,831 - 2,531,943 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NINJ1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	42,654,228 - 42,672,778 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	42,654,536 - 42,672,830 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

NINJ1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	103,509,950 - 103,523,158 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	103,510,454 - 103,523,084 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	91,784,589 - 91,798,519 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ninj1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	3,430,209 - 3,445,542 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624868	3,430,539 - 3,442,205 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ninj1
26 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	93
Count of miRNA genes:	80
Interacting mature miRNAs:	86
Transcripts:	ENSRNOT00000022341
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	69599340	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9991286	40540197	Rat
631499	Stl1	Serum triglyceride level QTL 1	3.6		blood triglyceride amount (VT:0002644)	blood triglyceride level (CMO:0000118)	17	3271398	27389946	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4354487	27028127	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2115149	34551001	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9201365	23653323	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1354651	Lmblg2	Limb length QTL 2	6		tibia length (VT:0004357)	tibia length (CMO:0000450)	17	4299130	69599340	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31701463	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4528038	49528038	Rat
1354630	Cm34	Cardiac mass QTL 34	8.7		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	4299130	69599340	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9201365	23653323	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	4299130	69599340	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	13986773	21975515	Rat
1331720	Rf43	Renal function QTL 43	2.881		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	17	15330613	23017269	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	4299130	35837242	Rat
1331765	Hrtrt15	Heart rate QTL 15	4.094		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	17	15330613	55836425	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	4299130	21293263	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4528038	49528038	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	1	31990913	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7979968	16317111	Rat
2303561	Bw91	Body weight QTL 91	2		body mass (VT:0001259)	body weight (CMO:0000012)	17	8868462	53868462	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	37830672	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9201365	23653323	Rat
1354596	Bw32	Body weight QTL 32	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	17	4299130	60781592	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	69599340	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4354487	27028127	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	60781592	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2115149	21881669	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22871563	Rat

Markers in Region

RH128424

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	15,452,994 - 15,453,192 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	15,866,419 - 15,866,616	NCBI	Rnor6.0
Rnor_5.0	17	17,930,236 - 17,930,433	UniSTS	Rnor5.0
RGSC_v3.4	17	21,410,885 - 21,411,082	UniSTS	RGSC3.4
Celera	17	15,182,819 - 15,183,016	UniSTS
RH 3.4 Map	17	175.3	UniSTS
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063276077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063276078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U72660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022341 ⟹ ENSRNOP00000022341

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	15,452,813 - 15,461,704 (-)	Ensembl
Rnor_6.0 Ensembl	17	15,866,237 - 15,881,327 (-)	Ensembl

RefSeq Acc Id:

NM_012867 ⟹ NP_036999

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,659,208 - 15,668,031 (-)	NCBI
mRatBN7.2	17	15,452,811 - 15,461,635 (-)	NCBI
Rnor_6.0	17	15,866,235 - 15,881,284 (-)	NCBI
Rnor_5.0	17	17,930,052 - 17,945,126 (-)	NCBI
RGSC_v3.4	17	21,410,701 - 21,419,472 (-)	RGD
Celera	17	15,182,635 - 15,191,450 (-)	RGD

Sequence:

show sequence

CCATGGATCCCGGCACCGAGGAGTACGAGCTCAACGGCGACCTGCGCCCTGGCTCTCCCGGTTC
CCCCGACGCCTCGCCACCCCGCTGGGGTTTGAGGAACCGGCCCATCAATGTAAACCATTACGCC
AACAAGAAGAGCGCCGCGGAGAGCATGCTGGACATCGCACTGCTCATGGCCAACGCGTCGCAGC
TCAAGGCCGTGGTGGAGCAGGGCAATGAGTTCGCCTTCTTCGTGCCCCTCGTGGTGCTCATCTC
CATCTCTCTCGTGCTGCAGATCGGAGTGGGCGTGCTGCTCATCTTCCTGGTCAAGTATGACCTC
AACAACCCAGCCAAGCACGCCAAGCTGGACTTCCTTAACAACCTGGCCACGGGGCTGGTTTTCA
TCATCGTGGTGGTCAACATCTTCATTACGGCCTTTGGAGTCCAGAAGCCTGTCATGGACGTGGC
ACCCCGGCAGTAGGATGCCCAGAGACCTTGAAGGTATCTGACCTGCAGCCCAGCTGTCCAGACC
CCTGCAACTGCTGTATCCCCAAGGCATCCCTCTCCTGTTCACAGCCCAAGGTGGCCTCCGCTGG
ACCATGGTCAAGGATGGACTTCCGTCCACCTGTGACTGCTGCGTGGGCGGCCACCCGAGGCGTG
TGGGAACTGGATGCAAAGCCATGAAGATCAGAACTGGACAGTTCCACCGAAACCCACGCCCAGA
GGATGATCACTGCCCGCCCAAGGACATGCAGGAAATCCATGATTGGACTCGATGAGGGGCCAGA
ACTGATCTCTGTCTCAGGACATTCCAGAAGGACCAGGATATGCCCCTCCCTTTGCTGATACACC
AGTGACCCTACTTCTCATGGAGCATGCACAGGTCACCCTGGAGACTGCTCCCTTTGTTGTTTCC
TGACCCAGGGACCTTGGACAGTCATCAGTACCTGCTGGCTCCAGCCTCAGTGCCTGGGCTTGGC
AGTGTCTCTTGGCATCGAGAGGCAGCCATGCCTGTGGGGGCTGCAGGTCATCCTGGTACCTTCT
ACCAGTAGTGACTTGGGAAGAGCCCCACCCCCCAACCCAGGGGCTCAGGCCCCAATTTTCTAAT
CAGGAATGACAATAAAGCTTATGTCTTCCCCC

hide sequence

RefSeq Acc Id:

XM_063276077 ⟹ XP_063132147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,659,208 - 15,668,115 (-)	NCBI

RefSeq Acc Id:

XM_063276078 ⟹ XP_063132148

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,659,208 - 15,664,277 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_036999	(Get FASTA)	NCBI Sequence Viewer
	XP_063132147	(Get FASTA)	NCBI Sequence Viewer
	XP_063132148	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB17559	(Get FASTA)	NCBI Sequence Viewer
	EDL98126	(Get FASTA)	NCBI Sequence Viewer
	EDL98127	(Get FASTA)	NCBI Sequence Viewer
	EDL98128	(Get FASTA)	NCBI Sequence Viewer
	EDL98129	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022341
	ENSRNOP00000022341.1
GenBank Protein	P70617	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_036999 ⟸ NM_012867
- UniProtKB:	P70617 (UniProtKB/Swiss-Prot), A6J6X6 (UniProtKB/TrEMBL), A6J6X8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDPGTEEYELNGDLRPGSPGSPDASPPRWGLRNRPINVNHYANKKSAAESMLDIALLMANASQL KAVVEQGNEFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFI IVVVNIFITAFGVQKPVMDVAPRQ hide sequence

Ensembl Acc Id:

ENSRNOP00000022341 ⟸ ENSRNOT00000022341

RefSeq Acc Id:	XP_063132147 ⟸ XM_063276077
- Peptide Label:	isoform X1
- UniProtKB:	P70617 (UniProtKB/Swiss-Prot), A6J6X6 (UniProtKB/TrEMBL), A6J6X8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063132148 ⟸ XM_063276078
- Peptide Label:	isoform X2
- UniProtKB:	A6J6X9 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P70617-F1-model_v2	AlphaFold	P70617	1-152	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700357

Promoter ID:

EPDNEW_R10881

Type:

initiation region

Name:

Ninj1_1

Description:

ninjurin 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	15,881,316 - 15,881,376	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3179	AgrOrtholog
BioCyc Gene	G2FUF-9989	BioCyc
Ensembl Genes	ENSRNOG00000016587	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022341	ENTREZGENE
	ENSRNOT00000022341.5	UniProtKB/Swiss-Prot
InterPro	Ninjurin	UniProtKB/Swiss-Prot
KEGG Report	rno:25338	UniProtKB/Swiss-Prot
NCBI Gene	25338	ENTREZGENE
PANTHER	PTHR12316	UniProtKB/Swiss-Prot
	PTHR12316:SF19	UniProtKB/Swiss-Prot
Pfam	Ninjurin	UniProtKB/Swiss-Prot
PhenoGen	Ninj1	PhenoGen
RatGTEx	ENSRNOG00000016587	RatGTEx
TIGR	TC205662
UniProt	A6J6X6	ENTREZGENE, UniProtKB/TrEMBL
	A6J6X7_RAT	UniProtKB/TrEMBL
	A6J6X8	ENTREZGENE, UniProtKB/TrEMBL
	A6J6X9	ENTREZGENE, UniProtKB/TrEMBL
	NINJ1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-11-06	Ninj1	ninjurin 1		Ninjurin	Symbol and Name updated	625702	APPROVED
2002-06-10	Ninj1	Ninjurin			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to the cell surface	729059
gene_process	may play a role in nerve regeneration	729059

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD