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Gene: Foxl2 (forkhead box L2) Rattus norvegicus
Symbol: Foxl2
Name: forkhead box L2
RGD ID: 1310041
Description: Predicted to have several functions, including estrogen receptor binding activity; molecular function regulator; and ubiquitin conjugating enzyme binding activity. Predicted to be involved in several processes, including animal organ development; positive regulation of gonadotropin secretion; and regulation of transcription by RNA polymerase II. Predicted to localize to intercellular bridge; nuclear chromatin; and nucleoplasm. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and premature ovarian failure. Orthologous to human FOXL2 (forkhead box L2); INTERACTS WITH all-trans-retinoic acid; mono(2-ethylhexyl) phthalate; oxybenzone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: forkhead box protein L2; LOC367152
Homo sapiens (human) : FOXL2 (forkhead box L2)  HGNC  Alliance
Mus musculus (house mouse) : Foxl2 (forkhead box L2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxl2 (forkhead box L2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXL2 (forkhead box L2)
Canis lupus familiaris (dog) : FOXL2 (forkhead box L2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxl2 (forkhead box L2)
Sus scrofa (pig) : FOXL2 (forkhead box L2)
Chlorocebus sabaeus (African green monkey) : FOXL2 (forkhead box L2)
Heterocephalus glaber (naked mole-rat) : Foxl2 (forkhead box L2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08107,194,492 - 107,197,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,194,551 - 107,195,675 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,618,909 - 106,622,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,804,019 - 103,805,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18103,818,892 - 103,825,932 (+)NCBI
Celera898,919,088 - 98,922,240 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Foxl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310041
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.