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Gene: Foxl2 (forkhead box L2) Rattus norvegicus
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Symbol: Foxl2
Name: forkhead box L2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; estrogen receptor binding activity; and ubiquitin conjugating enzyme binding activity. Predicted to be involved in several processes, including animal organ development; positive regulation of gonadotropin secretion; and regulation of transcription by RNA polymerase II. Predicted to localize to the intercellular bridge and nucleus. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and premature ovarian failure. Orthologous to human FOXL2 (forkhead box L2); INTERACTS WITH all-trans-retinoic acid; mono(2-ethylhexyl) phthalate; oxybenzone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: forkhead box protein L2; LOC367152
Orthologs:
Homo sapiens (human) : FOXL2 (forkhead box L2)  HGNC  Alliance
Mus musculus (house mouse) : Foxl2 (forkhead box L2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxl2 (forkhead box L2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXL2 (forkhead box L2)
Canis lupus familiaris (dog) : FOXL2 (forkhead box L2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxl2 (forkhead box L2)
Sus scrofa (pig) : FOXL2 (forkhead box L2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08107,194,492 - 107,197,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,618,909 - 106,622,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,804,019 - 103,805,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18103,818,892 - 103,825,932 (+)NCBI
Celera898,919,088 - 98,922,240 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Foxl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310041
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.