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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoconazole
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Accession:CHEBI:82865 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-isoconazole. A broad-spectrum antibacterial drug used (as its nitrate salt) for treatment of dermatomycoses.
Synonyms:exact_synonym: rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (RS)-isoconazole;   1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole;   Formula=C18H14Cl4N2O;   isoconazol;   isoconazolum;   rac-isoconazole;   racemic isoconazole
 xref: CAS:27523-40-6;   KEGG:D04624
 xref_mesh: MESH:C020382
 xref: PMID:21391489;   PMID:22285524;   PMID:23135097;   PMID:23563768;   PMID:23574019;   PMID:23574020;   PMID:23574021;   PMID:23574022;   PMID:23574023;   PMID:23574025;   PMID:23574026;   PMID:3043949;   PMID:3537934;   PMID:3606700;   PMID:3910548;   PMID:460303;   PMID:470977;   PMID:582987;   Reaxys:6442235;   Wikipedia:Isoconazole


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isoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO isoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    chemical entity 19791
      chemical substance 11945
        mixture 10866
          racemate 9761
            isoconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic molecule 19483
                              organic cyclic compound 19252
                                organic heterocyclic compound 18422
                                  heteroarene 16462
                                    monocyclic heteroarene 13315
                                      azole 12480
                                        diazole 8135
                                          imidazoles 7662
                                            1-\{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl\}imidazole 1
                                              (R)-isoconazole 1
                                                isoconazole 1
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