Gene: Gucy1a3 (guanylate cyclase 1 soluble subunit alpha 3) Rattus norvegicus
Symbol: Gucy1a3
Name: guanylate cyclase 1 soluble subunit alpha 3
Description: ENCODES a protein that exhibits adenylate cyclase activity; cytidylate cyclase activity; GTP binding; INVOLVED IN cGMP biosynthetic process; nitric oxide mediated signal transduction; response to herbicide; PARTICIPATES IN long term depression; purine metabolic pathway; ASSOCIATED WITH Carcinoma, Adenoid Cystic (ortholog); Colonic Neoplasms (ortholog); Coronary Artery Disease (ortholog); FOUND IN guanylate cyclase complex, soluble; protein complex; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
Also known as: GCS-alpha-1; GCS-alpha-3; guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit alpha-3; Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase); Gucy1a1; SGC; soluble guanylate cyclase; soluble guanylate cyclase large subunit
Homo sapiens (human) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)  HGNC  AGR
Mus musculus (house mouse) : Gucy1a1 (guanylate cyclase 1, soluble, alpha 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
Canis lupus familiaris (dog) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1)
more info ...
Allele / Splice: Gucy1a3em1Mcwi  
Genetic Models: SS-Gucy1a3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gucy1a3
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68436
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE