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Gene: Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1) Rattus norvegicus
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Symbol: Gucy1a1
Name: guanylate cyclase 1 soluble subunit alpha 1
Description: Exhibits ion binding activity and protein heterodimerization activity. Contributes to adenylate cyclase activity and cytidylate cyclase activity. Involved in response to herbicide and response to organic cyclic compound. Localizes to the guanylate cyclase complex, soluble. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1); PARTICIPATES IN long term depression; purine metabolic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GCS-alpha-1; GCS-alpha-3; guanylate cyclase 1 soluble subunit alpha 3; guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit alpha-1; guanylate cyclase soluble subunit alpha-3; Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase); Gucy1a3; SGC; soluble guanylate cyclase; soluble guanylate cyclase large subunit
Orthologs:
Homo sapiens (human) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Gucy1a1 (guanylate cyclase 1, soluble, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
Canis lupus familiaris (dog) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1)
Sus scrofa (pig) : GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
more info ...
Allele / Splice: Gucy1a3em1Mcwi  
Genetic Models: SS-Gucy1a3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gucy1a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68436
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.