Gucy1a1 (guanylate cyclase 1, soluble, alpha 1) - Rat Genome Database

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Gene: Gucy1a1 (guanylate cyclase 1, soluble, alpha 1) Mus musculus
Analyze
Symbol: Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
RGD ID: 68654
MGI Page MGI
Description: Predicted to enable guanylate cyclase activity and ion binding activity. Predicted to contribute to adenylate cyclase activity and cytidylate cyclase activity. Involved in retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Acts upstream of or within several processes, including cGMP biosynthetic process; positive regulation of nitric oxide mediated signal transduction; and relaxation of vascular associated smooth muscle. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study primary open angle glaucoma. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1200016O07Rik; alpha 1 sGC; GCS-alpha-1; GCS-alpha-3; guanylate cyclase 1, soluble, alpha 3; guanylate cyclase soluble subunit alpha-1; guanylate cyclase soluble subunit alpha-3; Gucy1a; Gucy1a3; sGC-a; sGC-alpha1; soluble guanylate cyclase large subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39381,999,734 - 82,053,253 (-)NCBIGRCm39mm39
GRCm39 Ensembl381,999,734 - 82,053,096 (-)Ensembl
GRCm38382,092,427 - 82,145,946 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,092,427 - 82,145,789 (-)EnsemblGRCm38mm10GRCm38
MGSCv37381,896,349 - 81,949,799 (-)NCBIGRCm37mm9NCBIm37
MGSCv36382,178,354 - 82,231,000 (-)NCBImm8
Celera382,117,270 - 82,170,809 (-)NCBICelera
Cytogenetic Map3E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3',5'-cyclic GMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
apocynin  (ISO)
aristolochic acid  (ISO)
arotinoid acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
calcitriol  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
CHIR 99021  (ISO)
chloroprene  (EXP,ISO)
cinaciguat  (ISO)
clobetasol  (EXP)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diethyl malate  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
ferroheme b  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
glafenine  (ISO)
GTP  (ISO)
heme b  (ISO)
hydrogen peroxide  (ISO)
hydroxocobalamin  (ISO)
isoflavones  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
menadione  (ISO)
methylseleninic acid  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nickel atom  (ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
nitroglycerin  (ISO)
nitroprusside  (ISO)
NONOate(1-)  (ISO)
oxaliplatin  (ISO)
p-toluidine  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
PhIP  (ISO)
pioglitazone  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (EXP)
potassium hexacyanoferrate(3-)  (ISO)
progesterone  (ISO)
protoporphyrin  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
sodium arsenate  (EXP)
Soman  (ISO)
taurine  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
tunicamycin  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
XAV939  (ISO)
zinc protoporphyrin  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:10984516   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14681479   PMID:14715267   PMID:16141072   PMID:16141073   PMID:16614755  
PMID:16707424   PMID:16886062   PMID:16934000   PMID:17251421   PMID:17610859   PMID:17679618   PMID:17717014   PMID:17855621   PMID:17954614   PMID:18287559   PMID:18339647   PMID:18550612  
PMID:19030180   PMID:19345227   PMID:19386638   PMID:19502556   PMID:19592461   PMID:19625524   PMID:19934018   PMID:20023176   PMID:20392955   PMID:21078983   PMID:21257915   PMID:21267068  
PMID:21394564   PMID:21410795   PMID:21536853   PMID:21677750   PMID:21873635   PMID:21931083   PMID:22095726   PMID:22565307   PMID:23201547   PMID:23448871   PMID:23527308   PMID:23934853  
PMID:23934926   PMID:24155296   PMID:24213632   PMID:26590321   PMID:27199131   PMID:27315776   PMID:27505125   PMID:27520736   PMID:28465505   PMID:28782641   PMID:28973329   PMID:30030528  
PMID:30213732   PMID:30260287   PMID:30635555   PMID:31624071   PMID:34830371   PMID:35175194  


Genomics

Comparative Map Data
Gucy1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39381,999,734 - 82,053,253 (-)NCBIGRCm39mm39
GRCm39 Ensembl381,999,734 - 82,053,096 (-)Ensembl
GRCm38382,092,427 - 82,145,946 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,092,427 - 82,145,789 (-)EnsemblGRCm38mm10GRCm38
MGSCv37381,896,349 - 81,949,799 (-)NCBIGRCm37mm9NCBIm37
MGSCv36382,178,354 - 82,231,000 (-)NCBImm8
Celera382,117,270 - 82,170,809 (-)NCBICelera
Cytogenetic Map3E3NCBI
GUCY1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,666,848 - 155,737,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4155,666,726 - 155,737,059 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,588,000 - 156,658,211 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,807,328 - 156,871,232 (+)NCBINCBI36hg18NCBI36
Build 344156,945,482 - 157,009,379NCBI
Celera4153,919,477 - 153,989,823 (+)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4152,327,271 - 152,397,264 (+)NCBIHuRef
CHM1_14156,565,607 - 156,635,931 (+)NCBICHM1_1
T2T-CHM13v2.04158,999,647 - 159,069,856 (+)NCBI
Gucy1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22167,418,615 - 167,482,293 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2167,418,640 - 167,481,671 (-)Ensembl
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,045,703 - 181,102,918 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBICelera
Cytogenetic Map2q34NCBI
Gucy1a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,424,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,367,318 - 11,422,199 (-)NCBIChiLan1.0ChiLan1.0
GUCY1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14159,850,092 - 159,920,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,850,107 - 159,913,338 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04148,032,167 - 148,102,757 (+)NCBIMhudiblu_PPA_v0panPan3
GUCY1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11553,172,914 - 53,236,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1553,174,157 - 53,234,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,510,720 - 53,570,219 (+)NCBI
ROS_Cfam_1.01553,880,516 - 53,943,086 (+)NCBI
ROS_Cfam_1.0 Ensembl1553,881,077 - 53,942,856 (+)Ensembl
UMICH_Zoey_3.11553,134,895 - 53,194,847 (+)NCBI
UNSW_CanFamBas_1.01553,244,742 - 53,304,495 (+)NCBI
UU_Cfam_GSD_1.01553,557,797 - 53,618,055 (+)NCBI
Gucy1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,135,116 - 37,192,728 (-)NCBI
SpeTri2.0NW_0049365762,353,874 - 2,411,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl844,449,232 - 44,518,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1844,448,758 - 44,520,737 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2846,457,572 - 46,537,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17102,206,438 - 102,310,535 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl7102,238,477 - 102,303,673 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603781,715,008 - 81,968,286 (+)NCBIVero_WHO_p1.0
Gucy1a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248482,525,153 - 2,560,025 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248482,522,935 - 2,588,758 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Gucy1a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E3UniSTS
cM Map3 UniSTS
Gucy1a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E3UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:792
Count of miRNA genes:451
Interacting mature miRNAs:530
Transcripts:ENSMUST00000048976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000048976   ⟹   ENSMUSP00000048918
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl381,999,744 - 82,053,094 (-)Ensembl
GRCm38.p6 Ensembl382,092,437 - 82,145,787 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191942
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,014,104 - 82,053,096 (-)Ensembl
GRCm38.p6 Ensembl382,106,797 - 82,145,789 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192289   ⟹   ENSMUSP00000141478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,001,859 - 82,009,418 (-)Ensembl
GRCm38.p6 Ensembl382,094,552 - 82,102,111 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193924   ⟹   ENSMUSP00000142138
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl381,999,734 - 82,052,380 (-)Ensembl
GRCm38.p6 Ensembl382,092,427 - 82,145,073 (-)Ensembl
RefSeq Acc Id: ENSMUST00000194788
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,026,475 - 82,052,912 (-)Ensembl
GRCm38.p6 Ensembl382,119,168 - 82,145,605 (-)Ensembl
RefSeq Acc Id: NM_001356987   ⟹   NP_001343916
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39381,999,734 - 82,052,380 (-)NCBI
GRCm38382,092,427 - 82,145,073 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001356988   ⟹   NP_001343917
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39381,999,734 - 82,052,957 (-)NCBI
GRCm38382,092,427 - 82,145,650 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021896   ⟹   NP_068696
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39381,999,734 - 82,053,253 (-)NCBI
GRCm38382,092,427 - 82,145,946 (-)NCBI
MGSCv37381,896,349 - 81,949,799 (-)RGD
Celera382,117,270 - 82,170,809 (-)RGD
cM Map3 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_068696   ⟸   NM_021896
- UniProtKB: Q9ERL9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001343917   ⟸   NM_001356988
RefSeq Acc Id: NP_001343916   ⟸   NM_001356987
RefSeq Acc Id: ENSMUSP00000048918   ⟸   ENSMUST00000048976
RefSeq Acc Id: ENSMUSP00000142138   ⟸   ENSMUST00000193924
RefSeq Acc Id: ENSMUSP00000141478   ⟸   ENSMUST00000192289
Protein Domains
Guanylate cyclase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERL9-F1-model_v2 AlphaFold Q9ERL9 1-691 view protein structure

Promoters
RGD ID:6849136
Promoter ID:MM_XEF:4580
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:NM_001017725
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36381,912,654 - 81,913,154 (-)MPROMDB
RGD ID:6833928
Promoter ID:MM_KWN:34673
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:UC008POT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36381,949,091 - 81,949,591 (-)MPROMDB
RGD ID:6880958
Promoter ID:EPDNEW_M3930
Type:initiation region
Name:Gucy1a1_1
Description:Mus musculus guanylate cyclase 1, soluble, alpha 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38382,145,778 - 82,145,838EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1926562 AgrOrtholog
Ensembl Genes ENSMUSG00000033910 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000048918 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141478.2 UniProtKB/TrEMBL
  ENSMUSP00000142138 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000048976 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000192289.2 UniProtKB/TrEMBL
  ENSMUST00000193924 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.450.260 UniProtKB/Swiss-Prot
  3.30.70.1230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1520.10 UniProtKB/Swiss-Prot
InterPro A/G_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/Swiss-Prot
  H-NOX_domain_sf UniProtKB/Swiss-Prot
  HNOB_dom_associated UniProtKB/Swiss-Prot
  HNOB_dom_associated_sf UniProtKB/Swiss-Prot
  NO_sig/Golgi_transp_ligand-bd UniProtKB/Swiss-Prot
  Nucleotide_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:60596 UniProtKB/Swiss-Prot
MGD MGI:1926562 ENTREZGENE
NCBI Gene 60596 ENTREZGENE
Pfam Guanylate_cyc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNOBA UniProtKB/Swiss-Prot
PhenoGen Gucy1a1 PhenoGen
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/Swiss-Prot
  GUANYLATE_CYCLASE_2 UniProtKB/Swiss-Prot
SMART CYCc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF111126 UniProtKB/Swiss-Prot
  SSF55073 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWB4_MOUSE UniProtKB/TrEMBL
  GCYA1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q6GTG0 UniProtKB/Swiss-Prot
  Q9DBQ3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-12 Gucy1a1  guanylate cyclase 1, soluble, alpha 1  Gucy1a3  guanylate cyclase 1, soluble, alpha 3  Symbol and/or name change 5135510 APPROVED